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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GRRPARCYRYIKNKPYPKSRFCRGVPDAKIRIFDLGNKRANVDTFPACVHMMSNEREHLSSEALEAARICANKYMVKNCG
KDGFHLRVRKHPFHVTRINKMLSCAGADRLQTGMRGAYGKPQGLVARVDIGDILFSMRIKEGNVKHAIEAFRRAKFKFPG
RQIIVSSRKWGFTKWDREDYERMRAEGRLRSDGVGVQLQREHGPLTKWIENPI

The query sequence (length=213) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 9bh5:CI 213 213 1.0000 1.0000 1.0000 3.26e-161 9cai:CI
2 8btk:BI 213 208 0.7230 0.7230 0.7404 4.33e-112 7a01:L2, 7a01:X2, 8a3d:p, 5aj0:AI, 8b5l:I, 8b6c:I, 9bdl:AL10, 9bdn:AL10, 9bdp:AL10, 7bhp:LI, 8bhf:r3, 8bpo:I2, 7cpu:LI, 7cpv:LI, 4d5y:I, 4d67:I, 6d90:I, 6d9j:I, 9f1b:BI, 9f1c:BI, 9f1d:BI, 7f5s:LI, 6frk:I, 6ftg:I, 6fti:I, 6ftj:I, 8g5y:LI, 8g5z:LI, 8g60:LI, 8g61:LI, 8g6j:LI, 8glp:LI, 6gz3:AI, 6gz4:AI, 6gz5:AI, 6hcf:I3, 6hcj:I3, 6hcm:I3, 6hcq:I3, 8ifd:2D, 8ife:2D, 6ip5:2D, 6ip6:2D, 6ip8:2D, 3j7o:I, 3j7p:I, 3j7q:I, 3j7r:I, 3j92:I, 3jag:I, 3jah:I, 3jai:I, 3jaj:I, 3jan:I, 8jdj:O, 8jdk:O, 8jdl:O, 8jdm:O, 8k2c:LI, 5lks:LI, 7ls1:D1, 7ls2:D1, 5lzs:I, 5lzt:I, 5lzu:I, 5lzv:I, 5lzw:I, 5lzx:I, 5lzy:I, 5lzz:I, 7mdz:I, 6mtb:I, 6mtc:I, 6mtd:I, 6mte:I, 7nfx:I, 7nwg:I3, 7nwh:I, 7nwi:I, 7o7y:BI, 7o7z:BI, 7o80:BI, 7o81:BI, 7obr:I, 8ohd:LI, 8oj0:LI, 8oj5:LI, 8oj8:LI, 6ole:K, 6olf:K, 6olg:AI, 6oli:K, 6olz:AI, 6om0:K, 6om7:K, 7oya:I1, 7oyb:I1, 7oyc:I1, 7oyd:I, 8p2k:BI, 6p5i:AI, 6p5j:AI, 6p5k:AI, 6p5n:AI, 8q7z:BI, 8q87:BI, 8qfd:I, 7qgg:K, 8qoi:LI, 7qvp:LI, 7qvp:MI, 7qwq:I, 7qwr:I, 7qws:I, 6qzp:LI, 6r5q:I, 6r6g:I, 6r6p:I, 6r7q:I, 8rjb:I, 8rjc:I, 8rjd:I, 8scb:I, 6sgc:I2, 6swa:I, 5t2c:p, 6t59:I3, 7tm3:I, 7toq:AL10, 7tor:AL10, 7tut:I, 7ucj:I, 7uck:I, 4ug0:LI, 4ujc:BI, 4ujd:AI, 4uje:CI, 4v5z:Bh, 4v6x:CI, 6xa1:LI, 7xnx:LI, 7xny:LI, 8xsx:LI, 8xsy:LI, 8xsz:LI, 6y0g:LI, 8y0w:LI, 8y0x:LI, 6y2l:LI, 6y57:LI, 6y6x:LI, 8yoo:LI, 8yop:LI, 6z6l:LI, 6z6m:LI, 6z6n:LI, 7zjw:LL, 7zjx:LL, 6zm7:LI, 6zme:LI, 6zmi:LI, 6zmo:LI, 6zvk:L2, 6zvk:X2
3 4v6w:CI 217 208 0.6808 0.6682 0.6971 7.62e-107 6xu6:CI, 6xu7:CI, 6xu8:CI
4 7olc:LI 217 205 0.6761 0.6636 0.7024 1.48e-104 7old:LI, 8oo0:LI, 7z3n:LI, 7z3o:LI
5 5an9:F 217 211 0.6338 0.6221 0.6398 2.28e-103 5anb:F, 5anc:F, 6qkl:F
6 7r81:L1 217 207 0.6620 0.6498 0.6812 3.42e-102
7 4v3p:LI 184 183 0.6479 0.7500 0.7541 1.17e-101 4v7e:CI
8 7azy:o 220 209 0.6385 0.6182 0.6507 7.91e-100 8aaf:r, 8agt:r, 8agu:r, 8agv:r, 8agw:r, 8agx:r, 8agz:r, 5apn:I, 5apo:I, 7b7d:LL, 8bip:LI, 8bjq:LI, 8bn3:M0, 8bqd:BD, 8bqx:BD, 8ccs:MM, 8cdl:MM, 8cdr:MM, 8ceh:MM, 8cf5:MM, 8cg8:MM, 8cgn:MM, 8civ:MM, 8cku:MM, 8cmj:MM, 5dat:M0, 5dat:m0, 5dc3:M0, 5dc3:m0, 5dge:M0, 5dge:m0, 5dgf:M0, 5dgf:m0, 5dgv:M0, 5dgv:m0, 8eub:AI, 8evp:AI, 8evq:AI, 8evr:AI, 8evs:AI, 8evt:AI, 8ewb:AI, 8ewc:AI, 5fci:M0, 5fci:m0, 5fcj:M0, 5fcj:m0, 5gak:s, 6gq1:I, 6gqb:I, 6gqv:I, 6hd7:s, 6hhq:r, 6hhq:CL, 5i4l:M0, 5i4l:m0, 6i7o:BD, 6i7o:YD, 5it7:II, 3j0l:J, 3j0q:J, 3j6x:50, 3j6y:50, 3j77:60, 3j78:60, 5juo:N, 5jup:N, 5jus:N, 5jut:N, 5juu:N, 8k2d:LI, 8k82:LI, 5lyb:M0, 5lyb:m0, 5m1j:I5, 5mc6:BD, 5mei:r, 5mei:CL, 7mpi:AI, 7mpj:AI, 6n8o:Z, 7n8b:AI, 5ndg:M0, 5ndg:m0, 5ndv:M0, 5ndv:m0, 5ndw:M0, 5ndw:m0, 7nrc:LL, 7nrd:LL, 5obm:M0, 5obm:m0, 6oig:I, 5on6:r, 5on6:CL, 7osa:uL16, 7osm:uL16, 8p8m:LN, 8p8n:LN, 8p8u:LN, 8pfr:LN, 6q8y:BD, 6qt0:q, 6qtz:q, 6r84:s, 6r86:s, 6r87:s, 6ri5:q, 7rr5:LI, 6s47:AL, 6snt:p, 6sv4:BD, 6sv4:YD, 6sv4:ZD, 6t4q:LI, 5t62:L, 5t6r:L, 6t7i:LI, 6t7t:LI, 6t83:Iy, 6t83:La, 5tbw:r, 5tbw:CL, 6tb3:BD, 5tga:M0, 5tga:m0, 5tgm:M0, 5tgm:m0, 6tnu:BD, 7too:AL10, 7top:AL10, 4u3m:M0, 4u3m:m0, 4u3n:M0, 4u3n:m0, 4u3u:M0, 4u3u:m0, 4u4n:M0, 4u4n:m0, 4u4o:M0, 4u4o:m0, 4u4q:M0, 4u4q:m0, 4u4r:M0, 4u4r:m0, 4u4u:M0, 4u4u:m0, 4u4y:M0, 4u4y:m0, 4u4z:M0, 4u4z:m0, 4u50:M0, 4u50:m0, 4u51:M0, 4u51:m0, 4u52:M0, 4u52:m0, 4u53:M0, 4u53:m0, 4u55:M0, 4u55:m0, 4u56:M0, 4u56:m0, 4u6f:M0, 4u6f:m0, 6uz7:AI, 4v4b:BI, 4v6i:BI, 4v7h:BI, 4v7r:BJ, 4v7r:DJ, 4v88:BI, 4v88:DI, 4v8t:I, 4v8y:BI, 4v8z:BI, 4v91:I, 6woo:I, 6xiq:I, 6xir:I, 8y0u:LI, 6z6j:LI, 6z6k:LI, 7zpq:BI, 7zrs:BI, 7zs5:BK, 7zuw:BI, 7zux:EI, 7zw0:LM
9 4v8m:BK 212 208 0.6338 0.6368 0.6490 1.87e-97 8ova:BK, 8ove:BK
10 8btd:LK 206 206 0.6338 0.6553 0.6553 3.10e-97 8bsi:LK, 8bsj:LK, 8btr:LK, 8fru:I, 7pwg:I, 7pwo:I2
11 3jcs:N 213 206 0.6385 0.6385 0.6602 4.25e-97 6az3:N, 8ovj:N, 8rxh:LN, 8rxx:LN, 5t2a:J
12 8ip8:HB 205 207 0.6385 0.6634 0.6570 2.50e-96 8ipa:HB, 8ipb:HB, 8jiv:CI
13 5xxb:I 193 205 0.6385 0.7047 0.6634 1.79e-95
14 8azw:g 209 206 0.6385 0.6507 0.6602 8.18e-95 8b2l:g3, 7qiw:L, 7qiz:L
15 3j79:Q 189 205 0.5822 0.6561 0.6049 1.39e-87 3jbn:AQ, 3jbo:AQ, 3jbp:AQ, 8tpu:AQ, 5umd:Q
16 6zu5:LI0 209 210 0.5915 0.6029 0.6000 1.70e-85
17 8c3a:r 208 205 0.5728 0.5865 0.5951 1.14e-84 8c3a:BE, 8cq7:r, 8cq7:BE, 8cqw:r, 8cqw:BE, 8cre:r, 8cre:BE, 8oeq:r, 8oeq:BE, 7pzy:r, 7q08:r, 7q0f:r, 7q0p:r, 7q0r:r, 8q5i:r
18 8p5d:LI0 217 216 0.5540 0.5438 0.5463 5.13e-83 8p60:LI0, 8p60:KI0, 7qca:LI0
19 4v8p:BH 201 207 0.5681 0.6020 0.5845 6.07e-83 4v8p:CH, 4v8p:EH, 4v8p:GH
20 6zj3:Lc 203 205 0.5446 0.5714 0.5659 1.47e-80
21 6rm3:LI0 216 210 0.5117 0.5046 0.5190 2.70e-79
22 7qep:M0 211 208 0.5493 0.5545 0.5625 9.63e-77
23 6w6l:K 152 175 0.5258 0.7368 0.6400 1.30e-74
24 5xy3:I 195 197 0.4836 0.5282 0.5228 6.59e-71
25 8fld:BE 160 181 0.4883 0.6500 0.5746 6.50e-65 8fle:BE, 8flf:BE, 6lqm:J, 7ow7:p
26 8eug:I 170 185 0.4366 0.5471 0.5027 3.80e-60 8eui:I
27 8br8:LK 156 181 0.4085 0.5577 0.4807 6.53e-53 8brm:LK
28 4v4n:AN 168 157 0.2958 0.3750 0.4013 4.05e-33 4v6u:BN
29 8hku:L10E 164 164 0.3005 0.3902 0.3902 6.36e-32 8hkv:L10E, 8hky:L10E, 8hkz:L10E, 8hl1:L10E, 8hl2:L10E, 8hl3:L10E, 8hl4:L10E, 8hl5:L10E
30 4v9f:H 165 153 0.2488 0.3212 0.3464 3.11e-25 3cc2:H, 3cc4:H, 3cc7:H, 3cce:H, 3ccj:H, 3ccl:H, 3ccm:H, 3ccq:H, 3ccr:H, 3ccs:H, 3ccu:H, 3ccv:H, 3cd6:H, 3cma:H, 3cme:H, 3cpw:H, 3g4s:H, 3g6e:H, 3g71:H, 3i55:H, 3i56:H, 2otj:H, 2otl:H, 2qa4:H, 2qex:H, 1s72:H, 1vq4:H, 1vq5:H, 1vq6:H, 1vq7:H, 1vq8:H, 1vq9:H, 1vqk:H, 1vql:H, 1vqm:H, 1vqn:H, 1vqo:H, 1vqp:H, 1yhq:H, 1yi2:H, 1yij:H, 1yit:H, 1yj9:H, 1yjn:H, 1yjw:H
31 6skg:BJ 171 157 0.2629 0.3275 0.3567 3.16e-25 6skf:BJ, 6th6:BJ
32 3cxc:H 156 156 0.2629 0.3590 0.3590 5.36e-22 1jj2:H, 1k73:J, 1k8a:J, 1k9m:J, 1kc8:J, 1kd1:J, 1kqs:H, 1m1k:J, 1m90:J, 1n8r:J, 1nji:J, 3ow2:H, 1q7y:J, 1q81:J, 1q82:J, 1q86:J, 1qvf:H, 1qvg:H, 1w2b:H
33 1ffk:F 157 156 0.2254 0.3057 0.3077 1.64e-11 4v4p:AP, 4v4r:BQ, 4v4s:BQ, 4v4t:BQ
34 6o8w:N 141 121 0.1596 0.2411 0.2810 0.059 8a57:P, 8a5i:P, 8a63:P, 7nhk:P, 7nhn:P, 6o8x:N, 6o8y:N, 6o8z:N, 6o90:N, 7p7q:P, 7p7r:P, 7p7s:P, 7p7t:P, 7p7u:P, 8uu4:O, 8uu5:O, 8uu6:O, 8uu7:O, 8uu8:O, 8uu9:O, 8uua:O, 6w6p:N, 6wu9:N
35 7aqc:M 138 109 0.1549 0.2391 0.3028 0.079 7aqd:M, 7as8:Q, 7as9:Q, 8buu:M, 6ha1:M, 6ha8:M, 6htq:M, 3j9w:BP, 5njt:f, 7o5b:j, 7ope:Q, 8qcq:M, 7qgu:M, 7qh4:M, 8qpp:j, 7qv1:M, 7qv2:M, 7qv3:M, 8r55:j, 8s1p:M, 8s1u:M, 6tnn:f, 6tpq:f
36 5myj:BP 134 111 0.1408 0.2239 0.2703 0.17
37 6ag0:C 483 62 0.0986 0.0435 0.3387 0.65 6ag0:A, 1hvx:A, 4uzu:A
38 2die:A 481 49 0.0845 0.0374 0.3673 0.68
39 6wte:A 567 49 0.0657 0.0247 0.2857 0.75 6wte:B
40 6wtf:A 542 49 0.0657 0.0258 0.2857 0.76 6wtf:B
41 6dzi:N 136 112 0.1408 0.2206 0.2679 0.77 6dzp:N, 7f0d:M, 8fr8:N, 8kab:N, 7kgb:M, 7msc:M, 7msh:M, 7msm:M, 7msz:M, 7mt2:M, 7mt3:M, 7mt7:M, 5o60:N, 5o61:N, 7s0s:O, 7sfr:M, 5v7q:M, 5v93:M, 8v9j:O, 8v9k:O, 8v9l:O, 7xam:N, 5xym:M, 8xz3:N, 7y41:N, 5zeb:N, 5zep:N, 5zet:N
42 8h3v:S 304 45 0.0657 0.0461 0.3111 0.83 8h3v:T, 8h3v:U, 8h3v:V
43 2d3l:A 481 47 0.0845 0.0374 0.3830 0.91 2d3n:A, 1wp6:A, 1wpc:A
44 3j6b:K 195 42 0.0845 0.0923 0.4286 0.93 5mrc:K, 5mre:K, 5mrf:K
45 9c4g:l 136 120 0.1408 0.2206 0.2500 0.96 8crx:l, 8cvm:l
46 5li0:P 141 123 0.1596 0.2411 0.2764 1.6 7asm:K, 7asn:Y, 7aso:P, 7asp:K, 6ddd:Y, 6ddg:Y, 6fxc:AK, 6fxc:BK, 5hkv:J, 5hl7:J, 6hma:K, 5nd8:P, 5nd9:P, 5ngm:AK, 7nhl:P, 7nhm:P, 5nrg:J, 8p2f:P, 8p2g:P, 8p2h:P, 7p48:K, 6s0x:K, 6s0z:K, 6s12:K, 6s13:K, 6sj6:P, 5t7v:LP, 5tcu:LP, 7ttu:Y, 7ttw:Y, 4wce:J, 4wf9:J, 4wfa:J, 4wfb:J, 6wqn:Y, 6wqq:Y, 6wrs:Y, 6wru:Y, 8y36:K, 8y37:K, 8y38:K, 8y39:K, 6yef:P
47 2gjp:A 481 47 0.0798 0.0353 0.3617 2.0 2gjr:A, 1w9x:A
48 6xyw:Am 142 19 0.0516 0.0775 0.5789 2.9
49 1bli:A 481 45 0.0704 0.0312 0.3333 3.2 1ob0:A, 6toy:A, 6toz:A, 6tp0:A, 6tp1:A, 6tp2:A
50 3bh4:A 483 52 0.0751 0.0331 0.3077 3.7 3bh4:B, 1e3x:A, 1e3z:A, 1e40:A, 1e43:A
51 8bip:B 796 69 0.0798 0.0214 0.2464 6.1 8bjq:B, 8bjq:D
52 7yjk:A 445 55 0.0751 0.0360 0.2909 8.0 7yjk:E, 7yjn:A, 7yjo:A
53 8p4e:O 695 80 0.0986 0.0302 0.2625 8.5 4n48:A, 4n48:B, 4n49:A, 8p4f:O
54 6hun:A 428 85 0.1033 0.0514 0.2588 9.3
55 2fty:A 532 54 0.0704 0.0282 0.2778 9.6 2fty:B, 2fty:C, 2fty:D, 2fvk:A, 2fvk:B, 2fvk:C, 2fvk:D, 2fvm:A, 2fvm:B, 2fvm:C, 2fvm:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218