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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GRQKARGAATRARQKQRASLETMDKAVQRFRLQNPDLDSEALLTLPLLQLVQKLQSGELSPEAVFFTYLGKAWEVNKGTN
CVTSYLTDCETQLSQAPRQGLLYGVPVSLKECFSYKGHDSTLGLSLNEGMPSESDCVVVQVLKLQGAVPFVHTNVPQSMF
SYDCSNPLFGQTMNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSAFCGICGLKPTGNRLSKSGLKGCVYG
QTAVQLSLGPMARDVESLALCLKALLCEHLFTLDPTVPPLPFREEVYRSSRPLRVGYYETDNYTMPSPAMRRALIETKQR
LEAAGHTLIPFLPNNIPYALEVLSTGGLFSDGGRSFLQNFKGDFVDPCLGDLILILRLPSWFKRLLSLLLKPLFPRLAAF
LNNMRPRSAEKLWKLQHEIEMYRQSVIAQWKAMNLDVLLTPMLGPALDLNTPGRATGAVSYTMLYNCLDFPAGVVPVTTV
TAEDDAQMELYKGYFGDIWDIILKKAMKNSVGLPVAVQCVALPWQEELCLRFMREVEQLMTPQK

The query sequence (length=544) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3qj9:A 549 544 0.9890 0.9800 0.9890 0.0 4do3:A, 4do3:B, 4hbp:A, 4hbp:B, 4j5p:A, 4j5p:B, 3k7f:A, 3k7f:B, 3k83:A, 3k83:B, 3k84:A, 3k84:B, 3lj6:A, 3lj6:B, 3lj7:A, 3lj7:B, 6mrg:A, 6mrg:B, 6mrg:C, 6mrg:D, 1mt5:A, 1mt5:B, 1mt5:C, 1mt5:D, 1mt5:E, 1mt5:F, 1mt5:G, 1mt5:H, 1mt5:I, 1mt5:J, 1mt5:K, 1mt5:L, 1mt5:M, 1mt5:N, 1mt5:O, 1mt5:P, 3oj8:A, 3oj8:B, 3ppm:A, 3ppm:B, 3pr0:A, 3pr0:B, 3qj9:B, 3qk5:A, 3qk5:B, 3qkv:A, 3qkv:B, 2vya:A, 2vya:B, 2wap:A, 2wap:B, 2wj1:A, 2wj1:B, 2wj2:A, 2wj2:B
2 5h6s:C 457 226 0.1176 0.1400 0.2832 9.58e-26 5h6s:A, 5h6s:B, 5h6s:D
3 3h0l:A 478 302 0.1636 0.1862 0.2947 5.05e-23 3h0l:D, 3h0l:G, 3h0l:J, 3h0l:M, 3h0l:P, 3h0l:S, 3h0l:V, 3h0m:A, 3h0m:D, 3h0m:G, 3h0m:J, 3h0m:M, 3h0m:P, 3h0m:S, 3h0m:V, 3h0r:A, 3h0r:D, 3h0r:G, 3h0r:J, 3h0r:M, 3h0r:P, 3h0r:S, 3h0r:V
4 3kfu:E 468 272 0.1728 0.2009 0.3456 1.54e-19 3kfu:H
5 6c6g:A 457 165 0.1213 0.1444 0.4000 1.31e-18 6c6g:B
6 6c6g:A 457 20 0.0221 0.0263 0.6000 0.22 6c6g:B
7 6dii:H 616 185 0.1121 0.0990 0.3297 4.16e-17 6dii:A, 6dii:B, 6dii:C, 6dii:D, 6dii:E, 6dii:F, 6dii:G, 6dii:I, 6dii:J, 6dii:K, 6dii:L, 8ey1:D, 8ey1:F, 8ey1:H, 8ey1:J, 8ey1:L, 8ey9:B, 8ey9:E, 8ey9:F, 8ey9:G, 8ey9:H, 8ey9:I
8 2dqn:A 485 207 0.1232 0.1381 0.3237 1.47e-16 2f2a:A
9 1m21:A 487 255 0.1415 0.1581 0.3020 1.51e-15 1m21:B
10 1o9o:A 412 211 0.1140 0.1505 0.2938 1.37e-11 1o9o:B, 1ocm:A, 1ocm:B
11 4yji:A 490 312 0.1599 0.1776 0.2788 2.28e-11
12 3a1i:A 508 167 0.1011 0.1083 0.3293 6.15e-11
13 3a2q:A 482 183 0.1066 0.1203 0.3169 1.16e-10
14 4n0i:A 450 212 0.1103 0.1333 0.2830 5.31e-07
15 6te4:A 564 269 0.1232 0.1188 0.2491 4.40e-05
16 4gys:B 461 138 0.0827 0.0976 0.3261 4.87e-05 4gys:A
17 3t7c:A 278 87 0.0496 0.0971 0.3103 0.88 3t7c:B, 3t7c:C, 3t7c:D
18 7mq8:NN 42 36 0.0257 0.3333 0.3889 2.3 7mq9:NN
19 7qep:D6 101 35 0.0257 0.1386 0.4000 5.1
20 8d4a:A 1207 89 0.0441 0.0199 0.2697 5.7 8d4b:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218