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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GRLRVVVLGSTGSIGTQALQVIADNPDRFEVVGLAAGGAHLDTLLRQRAQTGVTNIAVADEDIPYHGSDAATRLVEQTEA
DVVLNALVGALGLRPTLAALKTGARLALANKESLVAGGSLVLRAARPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTAS
GGPFRGWSAADLEHVTPEQAGAHPNTLNSASLVNKGLEVIETHLLFGIPYDRIDVVVHPQSIIHSMVTFIDGSTIAQASP
PDMKLPISLALGWPRRVSGAAAACDFHTASSWEFEPLDTDVFPAVELARQAGVAGGCMTAVYNAANEEAAAAFLAGRIGF
PAIVGIIADVLHAADQWAVEPATVDDVLDAQRWARERAQRAVSGM

The query sequence (length=365) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4aic:A 379 379 1.0000 0.9631 0.9631 0.0 4a03:A, 4a03:B, 4aic:B, 2c82:A, 2c82:B, 2jcv:A, 2jcv:B, 2jcx:A, 2jcx:B, 2jd0:A, 2jd1:A, 2jd1:B, 2jd2:A, 2jd2:B, 4ooe:A, 4ooe:B, 4ooe:C, 4ooe:D, 4oof:A, 4oof:B, 3ras:A, 3ras:B, 4rcv:A, 4rcv:B, 2y1c:A, 2y1c:B, 2y1d:B, 2y1e:A, 2y1e:B, 2y1f:A, 2y1f:B, 2y1g:A, 2y1g:B, 3zhx:A, 3zhx:B, 3zhy:A, 3zhy:B, 3zhz:A, 3zi0:A, 3zi0:B
2 2y1d:A 359 365 0.9836 1.0000 0.9836 0.0
3 7s04:A 396 395 0.4493 0.4141 0.4152 3.07e-89
4 1r0l:B 379 372 0.4192 0.4037 0.4113 5.46e-83 1r0l:A, 1r0l:C, 1r0l:D
5 8s65:B 411 403 0.4575 0.4063 0.4144 8.42e-79 8s65:A
6 6mh5:B 375 373 0.3753 0.3653 0.3673 1.21e-76 6mh5:A
7 3anl:A 400 395 0.4247 0.3875 0.3924 7.60e-72 3anl:B, 3anm:A, 3anm:B, 3ann:A, 3ann:B, 2egh:A, 2egh:B, 1jvs:A, 1jvs:B, 1ono:A, 1ono:B, 1onp:A, 1onp:B, 1q0h:A, 1q0l:A, 1q0q:A, 1q0q:B, 3r0i:A, 3r0i:B, 1t1r:A, 1t1r:B, 1t1s:A, 1t1s:B
8 5kqo:A 398 367 0.4055 0.3719 0.4033 6.37e-70 5kqo:B, 5krr:A, 5krr:B, 5ks1:A, 5ks1:B
9 4gae:A 416 402 0.3616 0.3173 0.3284 1.45e-69 3au8:A, 3au8:B, 3au9:A, 3au9:B, 3aua:A, 3aua:B, 4gae:B, 5jaz:A, 5jaz:B, 5jbi:A, 5jbi:B, 5jc1:A, 5jc1:B, 5jmp:A, 5jmp:B, 5jmw:A, 5jmw:B, 5jnl:A, 5jnl:B, 8jnv:A, 8jnv:B, 8jnw:A, 8jnw:B, 5jo0:A, 5jo0:B, 4kp7:A, 4kp7:B, 3wqq:A, 3wqq:B, 3wqr:A, 3wqr:B, 3wqs:B, 4y67:A, 4y67:B, 4y6p:A, 4y6p:B, 4y6r:A, 4y6r:B, 4y6s:A, 4y6s:B
10 3a06:B 373 372 0.3726 0.3646 0.3656 9.66e-65 3a06:A, 3a14:A, 3a14:B
11 5dul:B 390 391 0.3918 0.3667 0.3657 1.52e-64 5dul:A, 5dul:D, 3iie:A, 3iie:B
12 4zqg:A 408 384 0.3644 0.3260 0.3464 1.30e-62 4zqf:A, 4zqf:B, 4zqg:B, 4zqh:A, 4zqh:B
13 5dul:C 367 377 0.3644 0.3624 0.3528 3.48e-55
14 1ys4:A 348 154 0.1096 0.1149 0.2597 0.017 1ys4:B
15 8gjh:A 639 66 0.0575 0.0329 0.3182 0.26 8gjh:B, 8gjh:C, 8gjh:D, 8gjh:E, 8gjh:F
16 7p8p:B 147 73 0.0658 0.1633 0.3288 0.82 7p8p:D
17 1vef:A 387 101 0.0849 0.0801 0.3069 0.85 1vef:B, 1wkg:A, 1wkg:B, 1wkh:A, 1wkh:B
18 2vn8:A 358 87 0.0658 0.0670 0.2759 0.91 2vn8:B
19 2fit:A 130 68 0.0630 0.1769 0.3382 1.5 1fhi:A, 2fhi:A, 1fit:A, 3fit:A, 5fit:A, 6fit:A, 7p8p:A, 7p8p:C
20 1c7i:A 483 135 0.0959 0.0725 0.2593 3.6 1qe3:A
21 6tj5:A 131 41 0.0329 0.0916 0.2927 5.5
22 1uqw:A 487 149 0.0904 0.0678 0.2215 8.2 1uqw:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218