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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GRLIIVSNRVAPISEGGPAAGGLAVGVYDALKETGGMWFGWSGDVLSSGQPQIKVEERGPVTFATIALMRRDYDQYYRGF
SNATLWPAFHYRADLLQYDRHDFEGYWRVNAWLAQQLVPLLREDDVIWVHDYHLIPFAQALRAAGVKNRIGFFLHIPFPA
SQVLLAVPPHRELVEALCSFDLLGFQTAPDLRAFCDYIVNEANGTADPGPLTIHAFGRTLRAAAYPIGVYPDEIAELAKA
GERGKPVRTMKATLHSRKLIMSVDRLDYSKGLVERFRAFERLLEHSTAQRNKVSFLQIAPPTRADMHAYQDIRLQLEGES
GRINGRFAELDWTPILYIHKQYERSVLAALFRTAHVGYVTPLRDGMNLVAKEYVSAQDPENPGVLVLSRFAGAAQELDGA
LIVNPVDIDGMAEALARALDMPLAERQARHRDMMVQLRENNVSVWRDNFMRDLQG

The query sequence (length=455) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5v0t:E 457 457 0.9978 0.9934 0.9934 0.0 5v0t:A, 5v0t:B, 5v0t:C, 5v0t:D, 5v0t:F, 5v0t:G, 5v0t:H
2 5tvg:A 468 453 0.6308 0.6132 0.6336 0.0 5tvg:B, 5tvg:C, 5tvg:D, 5tvg:E, 5tvg:F, 5tvg:G, 5tvg:H, 5uof:B
3 2wtx:D 457 454 0.5385 0.5361 0.5396 1.17e-166 1gz5:A, 1gz5:B, 1gz5:C, 1gz5:D, 1uqt:A, 1uqt:B, 1uqu:A, 2wtx:A, 2wtx:B, 2wtx:C
4 5hut:A 469 467 0.3495 0.3390 0.3405 2.26e-93 5hut:B, 5huu:A, 5huu:B, 5huv:A, 5huv:B, 5hvl:A, 5hvl:B
5 5hvo:A 459 465 0.3429 0.3399 0.3355 1.31e-83 5hvo:B, 5hvo:C, 5hvo:D
6 6jbr:A 465 481 0.3516 0.3441 0.3326 8.75e-83 6jbr:B, 6jbr:D, 6jbr:F, 6jbr:H, 6jbr:K, 6jbr:M, 6jbr:O, 6jbw:A, 6jbw:B
7 5hvm:B 452 466 0.3495 0.3518 0.3412 8.89e-83 5hvm:A
8 8fhw:A 432 455 0.3341 0.3519 0.3341 9.43e-80 8fhw:B, 8fhw:C, 8fhw:D
9 5jio:A 467 461 0.3385 0.3298 0.3341 4.69e-70 5k41:A, 5k42:A, 5k44:A, 5k5c:A, 5l3k:A, 5l3k:B, 5l3k:C, 5l3k:D, 5l3k:E, 5l3k:F, 5l3k:G, 5l3k:H
10 8iye:A 475 291 0.1451 0.1389 0.2268 1.77e-04 4f96:B, 4f96:A, 4f97:A, 4f97:B, 4f9f:A, 4f9f:D, 4f9f:B, 4f9f:C, 4f9f:E, 4f9f:F, 8iye:B, 8iyf:A, 8iyf:B, 3t5t:A, 3t5t:B, 3t7d:A, 3t7d:B, 3vdn:B
11 6hyj:B 223 104 0.0637 0.1300 0.2788 0.13 6hyj:A, 6hyy:A, 6hyy:B, 1l8l:A, 1l8l:B, 1l8o:A, 1l8o:B, 1nnl:A, 1nnl:B, 6q6j:A, 6q6j:B
12 3q7j:A 780 92 0.0593 0.0346 0.2935 1.1 3q7j:B, 1z1w:A, 1z5h:A, 1z5h:B
13 2ioy:A 274 100 0.0549 0.0912 0.2500 1.2 2ioy:B
14 3vcr:A 216 41 0.0352 0.0741 0.3902 4.2 3vcr:B
15 4lei:A 375 101 0.0703 0.0853 0.3168 6.5 4lei:B
16 6d0g:A 299 114 0.0703 0.1070 0.2807 9.5

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218