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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLPRKGLYMANDLKLLRHHLQIPI
HFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRELWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIAT
PKVKNQLKETTEAACRYGAFGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPA

The query sequence (length=220) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3rpn:A 220 220 1.0000 1.0000 1.0000 1.50e-165 3rpn:B, 3rpn:C, 3rpn:F, 3rpn:D, 3rpn:E, 1yzx:A, 1yzx:B
2 1r4w:A 221 220 0.6909 0.6878 0.6909 7.80e-119 1r4w:B, 1r4w:C, 1r4w:D
3 3fz5:C 192 151 0.1636 0.1875 0.2384 2.70e-04 3fz5:A, 3fz5:B
4 2imd:A 203 208 0.2045 0.2217 0.2163 0.013 2ime:A, 2imf:A
5 1q2l:A 937 114 0.1364 0.0320 0.2632 0.14
6 1cz7:D 365 35 0.0636 0.0384 0.4000 0.86 1cz7:A, 1cz7:B, 1cz7:C, 3l1c:A, 1n6m:A, 2ncd:A, 3u06:A, 5w3d:A
7 3u06:B 344 35 0.0636 0.0407 0.4000 1.1 3l1c:B, 1n6m:B
8 3ex7:I 62 22 0.0455 0.1613 0.4545 2.2 2xb2:T, 2xb2:S
9 2vg8:A 465 29 0.0591 0.0280 0.4483 4.1 2vce:A, 2vch:A
10 8fmw:U 69 51 0.0727 0.2319 0.3137 6.0
11 4usz:A 415 39 0.0636 0.0337 0.3590 6.1 4cit:A
12 1aoz:A 552 80 0.0909 0.0362 0.2500 7.8 1aoz:B, 1aso:A, 1aso:B, 1asp:A, 1asp:B, 1asq:A, 1asq:B
13 3ww1:A 242 39 0.0636 0.0579 0.3590 7.8 3ww1:B, 3ww2:A, 3ww2:B, 3ww3:A, 3ww3:B, 3ww4:A, 3ww4:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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