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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GNVVAILGAQWGDEGKGKIIDMLSEYSDITCRFNGGANAGHTISVNDKKYALHLLPCGVLYDNNISVLGNGMVIHVKSLM
EEIESVGGKLLDRLYLSNKAHILFDIHQIIDSIQETKKLKEGKQIGTTKRGIGPCYSTKASRIGIRLGTLKNFENFKNMY
SKLIDHLMDLYNITEYDKEKELNLFYNYHIKLRDRIVDVISFMNTNLENNKKVLIEGANAAMLDIDFGTYPYVTSSCTTV
GGVFSGLGIHHKKLNLVVGVVKSYLTRVGCGPFLTELNNDVGQYLREKGHEYGTTTKRPRRCGWLDIPMLLYVKCINSID
MINLTKLDVLSGLEEILLCVNFKNKKTGELLEKGCYPVEEEISEEYEPVYEKFSGWKEDISTCNEFDELPENAKKYILAI
EKYLKTPIVWIGVGPNRKNMIVKK

The query sequence (length=424) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1p9b:A 424 424 1.0000 1.0000 1.0000 0.0
2 1dj3:A 432 429 0.4575 0.4491 0.4522 4.76e-127 1dj3:B
3 2dgn:A 431 427 0.4458 0.4385 0.4426 9.44e-126 1iwe:A, 1iwe:B, 1lny:A, 1lny:B, 1lon:A, 1loo:A, 1mez:A, 1mf0:A, 1mf1:A
4 5i34:A 429 430 0.4670 0.4615 0.4605 1.15e-125 5i34:B
5 1dj2:A 429 429 0.4552 0.4499 0.4499 1.43e-122 1dj2:B
6 2v40:A 419 427 0.4528 0.4582 0.4496 5.11e-121
7 4m9d:B 431 420 0.4033 0.3968 0.4071 7.36e-105 4m9d:A
8 1cg0:A 431 429 0.4033 0.3968 0.3986 8.38e-105 1cg1:A, 1cg3:A, 1cg4:A, 1ch8:A, 1cib:A, 2gcq:A, 1gim:A, 1gin:A, 1hon:A, 1hoo:A, 1juy:A, 1kjx:A, 1kkb:A, 1kkf:A, 1ksz:A, 1nht:A, 1qf4:A, 1qf5:A, 1son:A, 1soo:A
9 6jrq:A 407 420 0.3915 0.4079 0.3952 1.52e-101 6jrq:B, 6jrq:C, 6jrq:D
10 9f17:A 413 419 0.4009 0.4116 0.4057 2.53e-101 9f17:B, 7pvo:A, 8qwa:A, 6zxq:A
11 6c25:A 394 431 0.3373 0.3629 0.3318 3.18e-77
12 5k7x:A 337 424 0.2736 0.3442 0.2736 2.75e-43 5k7x:B, 5k7x:C, 5k7x:D, 5k7x:E, 5k7x:F
13 7vf6:A 366 352 0.1887 0.2186 0.2273 8.42e-13 7vf6:B
14 7odx:A 350 361 0.2075 0.2514 0.2438 6.82e-11
15 6tnh:A 345 271 0.1698 0.2087 0.2657 7.75e-11 6fko:A, 6fko:B, 6fm1:A, 6fm1:B, 6rm2:A, 6rm2:B, 6tnh:B
16 6fm3:A 304 275 0.1627 0.2270 0.2509 2.11e-08 6fm0:A, 6fm0:B
17 4p0q:B 284 148 0.0708 0.1056 0.2027 0.18 4p0r:B, 4p0r:D, 4p0s:B, 4p0s:H, 4p0s:F, 4p0s:D
18 4z7x:A 211 69 0.0495 0.0995 0.3043 2.2 4z7x:B
19 7qep:S8 164 103 0.0613 0.1585 0.2524 2.3
20 5yzg:y 112 64 0.0425 0.1607 0.2812 3.5 8i0w:z
21 1aye:A 401 90 0.0495 0.0524 0.2333 4.6 1dtd:A
22 1keq:A 238 38 0.0401 0.0714 0.4474 4.8 1dmx:A, 1dmx:B, 1dmy:A, 1dmy:B, 1keq:B, 1urt:A
23 7w15:A 294 77 0.0425 0.0612 0.2338 4.9 7w15:B, 7w19:A, 7w19:B, 7w1a:B, 7w1a:A
24 4zm4:B 425 93 0.0684 0.0682 0.3118 4.9 4zm3:A, 4zm3:B, 4zm3:C, 4zm3:D, 4zm4:A, 4zm4:C, 4zm4:E, 4zm4:F
25 7d4i:RP 2084 62 0.0472 0.0096 0.3226 5.7 7d5t:RP
26 4v59:D 1467 112 0.0825 0.0239 0.3125 6.5 4v59:A, 4v59:B, 4v59:C, 4v59:E, 4v59:F
27 4itu:A 253 72 0.0495 0.0830 0.2917 10.0 4gh5:A, 4gh5:B, 4gh5:C, 4gh5:D, 4itu:B, 4itu:C, 4itu:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218