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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GMSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNVISANVGQNPARQCALGAGL
EESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQE
LMGLQAEECAQDHGFSREQQDEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPA
FIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAIPKALKHAGVGQDAIDAF
EINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVELL

The query sequence (length=399) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6aqp:C 399 399 1.0000 1.0000 1.0000 0.0 6aqp:A, 6aqp:B, 6aqp:D, 6are:A, 6are:B, 6are:C, 6are:D
2 6bn2:A 393 393 0.5113 0.5191 0.5191 1.62e-139
3 2ib8:D 393 396 0.4862 0.4936 0.4899 2.92e-121 2f2s:A, 2f2s:B, 2f2s:C, 2f2s:D, 2ib8:A, 2ib8:B, 2ib8:C, 2ib9:A, 2ib9:B, 2ib9:C, 2ib9:D, 2ibu:A, 2ibu:B, 2ibu:C, 2ibu:D, 2ibw:A, 2ibw:B, 2ibw:C, 2ibw:D, 2iby:A, 2iby:B, 2iby:C, 2iby:D
4 6bja:A 382 393 0.4737 0.4948 0.4809 5.27e-116
5 6l2c:A 402 401 0.4712 0.4677 0.4688 4.32e-114 6l2c:B, 6l2c:C, 6l2c:D
6 6bjb:A 384 392 0.4812 0.5000 0.4898 5.64e-112 6bjb:B
7 7cw5:B 394 390 0.4612 0.4670 0.4718 5.20e-110 7cw5:A
8 4o9c:C 393 390 0.4862 0.4936 0.4974 5.49e-109
9 8gqn:A 390 392 0.4386 0.4487 0.4464 1.90e-105 8gqn:B, 8gqn:C, 8gqn:D
10 4xl4:A 392 394 0.4461 0.4541 0.4518 4.07e-103 4xl4:B
11 1wl4:A 394 392 0.4411 0.4467 0.4490 9.35e-103
12 1ou6:A 392 397 0.4436 0.4515 0.4458 1.09e-98 1dlv:A, 1dlv:B, 1dlv:C, 1dlv:D, 1dm3:A, 1dm3:B, 1dm3:C, 1dm3:D, 7lbz:A, 7lbz:B, 7lbz:C, 7lbz:D, 7lca:A, 7lca:B, 7lca:C, 7lca:D, 7lcl:A, 7lcl:B, 7lcl:C, 7lcl:D, 7ld2:A, 7ld2:B, 7ld2:C, 7ld2:D, 7ldc:A, 7ldc:B, 7ldc:C, 7ldc:D, 7ldt:A, 7ldt:B, 7ldt:C, 7ldt:D, 7ldu:A, 7ldu:B, 7ldu:C, 7ldu:D, 7ldv:A, 7ldv:B, 7ldv:C, 7ldv:D, 7ldw:A, 7ldw:B, 7ldw:C, 7ldw:D, 1m1o:A, 1m1o:B, 1m3z:A, 1m3z:B, 1m3z:C, 1m3z:D, 1nl7:A, 1nl7:B, 1ou6:B, 1qfl:A, 1qfl:B, 1qfl:C, 1qfl:D, 2vtz:A, 2vtz:B, 2vtz:C, 2vtz:D, 2vu0:A, 2vu0:B, 2vu1:A, 2vu1:B, 2vu2:A, 2vu2:B, 2wkt:A, 2wkt:B, 2wkt:C, 2wkt:D, 2wku:A, 2wku:B, 2wkv:A, 2wkv:B, 2wkv:C, 2wkv:D, 2wl4:A, 2wl4:B, 2wl5:A, 2wl5:B, 2wl5:C
13 5f38:D 394 399 0.4612 0.4670 0.4612 8.63e-94 5f38:B, 5f38:C
14 8jg2:A 393 396 0.4135 0.4198 0.4167 6.31e-92 8jg2:B
15 7fea:B 396 391 0.3910 0.3939 0.3990 2.80e-81 7ei4:A, 7ei4:B, 7ei4:C, 7ei4:D, 7fea:A, 7fea:C, 7fea:D
16 4c2j:D 395 397 0.3734 0.3772 0.3753 3.77e-77 4c2j:A, 4c2j:B, 4c2j:C
17 2d3t:C 390 398 0.3784 0.3872 0.3794 2.79e-71 2d3t:D, 1wdk:C, 1wdk:D, 1wdl:C, 1wdl:D, 1wdm:C, 1wdm:D
18 5bz4:K 400 398 0.3484 0.3475 0.3492 1.37e-65 5bz4:B, 5bz4:D, 5bz4:F, 5bz4:H
19 6pcb:A 403 409 0.3759 0.3722 0.3667 2.42e-58 6pcb:B, 6pcb:C, 6pcb:D, 6pcc:A, 6pcc:B, 6pcc:C, 6pcc:D, 6pcd:A, 6pcd:B, 6pcd:D
20 8gqm:A 377 393 0.3333 0.3528 0.3384 5.34e-50
21 7o4t:D 403 416 0.3383 0.3350 0.3245 2.05e-47 4b3i:C, 4b3j:C, 4b3j:D, 7o1i:D, 7o1l:D, 7o4r:C, 7o4r:D, 7o4s:C, 7o4s:D, 7o4t:C, 8opu:C, 8opu:D, 8opx:C, 8opx:D, 8opy:D, 8oql:C, 8oql:D, 8oqm:D, 8oqo:C, 8oqo:D, 8oqp:C, 8oqp:D, 8oqs:C, 8oqs:D, 8pf8:C, 8pf8:D
22 4ubt:A 396 400 0.3308 0.3333 0.3300 3.37e-43 4ubt:B, 4ubt:C, 4ubt:D, 4ubu:A, 4ubu:B, 4ubu:C, 4ubu:D, 4ubu:E, 4ubu:F, 4ubu:G, 4ubu:H, 4ubv:A, 4ubv:B
23 6esq:A 392 416 0.2657 0.2704 0.2548 2.52e-09 6esq:B, 6esq:C, 6esq:D
24 6hsj:B 390 381 0.2331 0.2385 0.2441 2.69e-08 6hsp:B
25 5lnq:A 430 315 0.1754 0.1628 0.2222 4.48e-06 5lnq:B, 5lnq:D, 5lot:A, 5lot:B, 5lot:D, 3zbn:A, 3zbn:B, 3zbn:D
26 7pyt:B 392 129 0.0877 0.0893 0.2713 1.06e-04 7pyt:D, 7yxm:B, 7yxm:D
27 4yzo:C 347 133 0.1028 0.1182 0.3083 0.001 4yzo:D
28 6mg0:B 1687 100 0.0752 0.0178 0.3000 0.035
29 6mfz:A 1789 100 0.0752 0.0168 0.3000 0.039 5es7:A, 5es8:A, 5es8:B, 5es9:A, 6mfw:A, 6mfx:A, 6mfy:A, 6mg0:A, 6ulz:A
30 5mg5:L 396 85 0.0652 0.0657 0.3059 0.059 5mg5:C, 5mg5:O, 5mg5:R
31 8cg5:A 1282 54 0.0376 0.0117 0.2778 0.18 6fij:B
32 2ix4:A 431 34 0.0426 0.0394 0.5000 0.32 2ix4:B
33 2epn:A 623 147 0.0927 0.0594 0.2517 0.49 2epn:B
34 6u5w:A 1435 37 0.0301 0.0084 0.3243 0.78
35 1ox0:A 414 38 0.0351 0.0338 0.3684 1.0 2alm:A, 1oxh:A, 1oxh:B, 1oxh:C, 1oxh:D
36 4ls8:A 416 50 0.0451 0.0433 0.3600 1.0 4ls7:A, 4ls7:B, 4ls8:B
37 7l4l:A 412 37 0.0401 0.0388 0.4324 1.1 1b3n:A, 3g0y:A, 3g11:A, 2gfx:A, 3hnz:A, 3ho2:A, 3ho9:A, 3i8p:A, 7l4e:A, 7l4l:B, 6okg:A, 6olt:A
38 8cg6:A 1208 38 0.0276 0.0091 0.2895 1.5
39 7b66:A 161 72 0.0602 0.1491 0.3333 1.6 7aom:A, 7aom:B, 7aop:A, 7b63:A, 7b63:B, 7b64:A, 7b65:A, 7b65:B, 7b66:B, 7b66:C, 7b66:D, 7b67:A, 7b67:B, 7b7v:A, 7b7v:B, 5bon:A, 5bon:B, 5bon:C, 5bon:D, 5bon:E, 5bon:F, 5bon:G, 5bon:H, 5lpg:A, 5lpg:B, 7nr6:A, 7nr6:B, 7r0d:AAA, 7r0d:BBB, 6t5j:A, 6t5j:B
40 4f32:B 423 30 0.0376 0.0355 0.5000 1.9 4f32:A
41 2iwz:A 426 34 0.0376 0.0352 0.4412 2.2 2iwz:B
42 6smp:B 417 47 0.0426 0.0408 0.3617 2.3 6smo:B, 6smo:D, 6smo:F, 6smp:E, 6smp:H, 6smp:K
43 5ux0:D 639 70 0.0476 0.0297 0.2714 2.6 5i4a:A, 5i4a:C, 5ux0:A
44 4c6v:A 415 29 0.0351 0.0337 0.4828 2.7 4c6u:A, 4c6w:A, 4c6w:B, 4c6x:A, 4c6x:B, 4c6z:A, 4c6z:B, 4c70:A, 4c70:B, 4c71:A, 4c71:B, 4c72:A, 4c72:B, 4c73:A, 4c73:B, 5ld8:A, 5ld8:B, 6p9k:A, 6p9l:A, 6p9m:A, 5w2o:A, 5w2p:A, 5w2q:A, 5w2s:A, 2wge:A, 2wgg:A, 2wgg:B, 2wgg:C, 2wgg:D, 2wgg:E, 2wgg:F, 2wgg:G, 2wgg:H, 6y2i:AAA, 6y2i:BBB, 6y2j:AAA, 6y2j:BBB, 6y2j:CCC, 6y2j:DDD, 6y2j:EEE, 6y2j:FFF, 6y2j:GGG, 6y2j:HHH
45 6ql9:D 1765 31 0.0226 0.0051 0.2903 4.0 3hmj:A, 3hmj:B, 3hmj:C, 8prv:A, 8prv:B, 8prw:A, 8prw:B, 8prw:C, 8prw:D, 8prw:E, 8prw:F, 8ps1:A, 6ql6:F, 6ql6:E, 6ql6:D, 6ql6:C, 6ql6:B, 6ql6:A, 6ql9:F, 6ql9:A, 6ql9:E, 6ql9:B, 6ql9:C, 6ta1:A, 6ta1:B, 6ta1:D, 6ta1:K, 6ta1:F, 6ta1:I, 6u5u:A, 2vkz:A, 2vkz:B, 2vkz:C, 2wat:A, 2wat:B, 2wat:C, 2wat:D, 2wat:E, 2wat:F
46 5a6a:B 597 134 0.0877 0.0586 0.2612 4.2 5a69:A
47 8cuy:A 1016 35 0.0326 0.0128 0.3714 4.8
48 5mcp:E 387 48 0.0476 0.0491 0.3958 4.8 5mcp:G
49 5a6k:A 626 134 0.0877 0.0559 0.2612 5.9 5a6a:A, 5a6b:A, 5a6b:B, 5a6b:C, 5a6b:D, 5a6k:B, 5ac4:A, 5ac4:B, 5ac5:A, 5ac5:B
50 4v59:D 1467 37 0.0301 0.0082 0.3243 5.9 4v59:A, 4v59:B, 4v59:C, 4v59:E, 4v59:F
51 4v8l:D 2822 76 0.0551 0.0078 0.2895 6.0 4ce4:o, 6hiv:US, 6hiv:UT, 6hiw:US, 6hiw:UT, 6hiy:US, 6hiy:UT, 4v8l:E, 4v8l:F, 4v8l:A, 4v8l:B, 4v8l:C, 4v8v:A, 4v8v:B, 4v8v:C, 4v8v:D, 4v8v:E, 4v8v:F, 4v8w:D, 4v8w:E, 4v8w:F, 4v8w:A, 4v8w:B, 4v8w:C
52 7m7f:A 1390 51 0.0426 0.0122 0.3333 6.0 2fr0:A, 2fr1:A, 7m7i:A
53 2gam:C 374 67 0.0451 0.0481 0.2687 6.1 2gam:A, 2gam:B, 2gam:D, 3otk:A, 3otk:B, 3otk:C, 3otk:D
54 8q0a:R 96 65 0.0451 0.1875 0.2769 6.5 7dgq:I, 7dgr:I, 7dgs:I, 7dgz:I, 7dh0:I, 7dkf:I2, 5lnk:b, 5o31:R, 8q0f:R, 8q0j:R, 8q0m:R, 8q0o:R, 8q0q:R, 8q1p:R, 8q1u:R, 8q1y:R, 8q25:R, 8q45:R, 8q46:R, 8q47:R, 8q48:R, 8q49:R, 8q4a:R, 6q9d:S6, 6qa9:S6, 6qbx:S6, 6qc2:S6, 6qc3:S6, 6qc4:S6, 6qc5:S6, 6qc6:S6, 6qc7:S6, 6qc8:S6, 7qsd:R, 7qsk:R, 7qsl:R, 7qsm:R, 7qsn:R, 7qso:R, 7r41:R, 7r42:R, 7r43:R, 7r44:R, 7r45:R, 7r46:R, 7r47:R, 7r48:R, 7r4c:R, 7r4d:R, 7r4f:R, 7r4g:R, 8ud1:1R, 8ueo:1R, 8uep:1R, 8ueq:1R, 8uer:1R, 8ues:1R, 8uet:1R, 8ueu:1R, 8uev:1R, 8uew:1R, 8uex:1R, 8uey:1R, 8uez:1R, 8ugh:1R, 8ugi:1R, 8ugj:1R, 8ugn:1R, 8ugn:5R, 8ugr:1R, 8ugr:5R, 7v2c:T, 7v2d:T, 7v2e:T, 7v2f:T, 7v2h:T, 7v2k:T, 7v2r:T, 7v30:T, 7v31:T, 7v32:T, 7v33:T, 7v3m:T, 7vb7:T, 7vbn:T, 7vbz:T, 7vwj:T, 7vxp:T, 7vxu:T, 7vy8:T, 7vya:T, 7vyf:T, 7vyh:T, 7vyn:T, 7vz1:T, 7vzv:T, 7vzw:T, 7w00:T, 7w0h:T, 7w0r:T, 7w0y:T, 7w1o:T, 7w1p:T, 7w1t:T, 7w1u:T, 7w1v:T, 7w1z:T, 7w20:T, 7w2k:T, 7w2l:T, 7w2r:T, 7w2u:T, 7w2y:T, 7w31:T, 7w32:T, 7w35:T, 7w4c:T, 7w4d:T, 7w4e:T, 7w4f:T, 7w4g:T, 7w4j:T, 7w4k:T, 7w4l:T, 7w4m:T, 7w4n:T, 7w4q:T, 7zd6:b, 7zdh:b, 7zdj:b, 7zdm:b, 7zdp:b, 7zeb:b, 6zk9:b, 6zkc:b, 6zkd:b, 6zke:b, 6zkf:b, 6zkg:b, 6zkh:b, 6zki:b, 6zkj:b, 6zkk:b, 6zkl:b, 6zkm:b, 6zkn:b, 6zko:b, 6zkp:b, 6zkq:b, 6zkr:b, 6zks:b, 6zkt:b, 6zku:b, 6zkv:b
55 2boy:A 253 45 0.0301 0.0474 0.2667 6.5 2boy:B, 2boy:C, 2boy:D, 2boy:E, 2boy:F, 2boy:G, 2boy:H
56 1yux:B 202 35 0.0376 0.0743 0.4286 6.7 1yux:A, 1yuz:A, 1yuz:B, 1yv1:A, 1yv1:B
57 7s6c:B 891 67 0.0426 0.0191 0.2537 6.8
58 6gjc:A 2770 76 0.0551 0.0079 0.2895 7.0 6gjc:B, 6gjc:C, 6gjc:D, 6gjc:E, 6gjc:F
59 7rfh:H 451 48 0.0401 0.0355 0.3333 8.0 7rfh:A, 7rfh:B, 7rfh:C, 7rfh:D, 7rfh:E, 7rfh:F, 7rfh:G
60 5mcp:C 446 50 0.0476 0.0426 0.3800 8.5 5mcp:A, 5mcp:B, 5mcp:D, 6rpu:A
61 7cpx:A 2262 32 0.0276 0.0049 0.3438 8.8 7cpx:B, 7cpy:A, 7cpy:B
62 2cyy:A 151 36 0.0351 0.0927 0.3889 9.2 2e1c:A, 2zny:A, 2zny:C, 2zny:E, 2zny:B, 2zny:D, 2zny:F, 2zny:H, 2zny:G, 2znz:A, 2znz:B, 2znz:C, 2znz:D, 2znz:E, 2znz:F, 2znz:G, 2znz:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218