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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GLYVEKVSGLRKDFIKGVDVSSIIALEESGVAFYNESGKKQDIFKTLKEAGVNYVRVRIWNDPYDANGNGYGGGNNDLEK
AIQIGKRATANGMKLLADFHYSDFWADPAKQKAPKAWANLNFEDKKTALYQYTKQSLKAMKAAGIDIGMVQVGNETNGGL
AGETDWAKMSQLFNAGSQAVRETDSNILVALHFTNPETSGRYAWIAETLHRHHVDYDVFASSYYPFWHGTLKNLTSVLTS
VADTYGKKVMVAATSYTYTAEDGDGHGNTAPKNGQTLNNPVTVQGQANAVRDVIQAVSDVGEAGIGVFYWEPAWIPVGPA
HRLEKNKALWETYGSGWATSYAAEYDPEDAGKWFGGSAVDNQALFDFKGRPLPSLHVFQYVDTGTPF

The query sequence (length=387) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2ccr:B 387 387 0.9974 0.9974 0.9974 0.0 2ccr:A, 2gft:A, 2gft:B, 2j74:A, 2j74:B, 1r8l:A, 1r8l:B, 1ur0:A, 1ur0:B, 1ur4:A, 1ur4:B
2 7osk:A 360 385 0.3773 0.4056 0.3792 4.21e-87 7osk:B
3 6q3r:A 334 314 0.2558 0.2964 0.3153 3.01e-44 6q3r:B
4 1hjs:A 332 378 0.2946 0.3434 0.3016 1.37e-40 1hju:A, 1hju:D
5 4bf7:A 335 312 0.2351 0.2716 0.2917 8.74e-39
6 6gpa:A 314 317 0.2506 0.3089 0.3060 9.52e-38 6gpa:B
7 3amg:B 291 171 0.0801 0.1065 0.1813 2.7
8 3amg:A 311 171 0.0801 0.0997 0.1813 3.3 3aof:B, 3aof:A, 3azr:A, 3azr:B, 3azs:A, 3azs:B, 3azt:A, 3azt:D, 3mmw:A, 3mmw:B, 3mmw:C, 3mmw:D
9 8wy4:A 451 169 0.0956 0.0820 0.2189 3.7 8wy4:B, 8wy4:D, 8wy4:C, 8wy5:A, 8wy5:B, 8wy5:C, 8wy5:D, 8x51:A, 8x51:B
10 8fhb:A 204 140 0.0724 0.1373 0.2000 3.8
11 6xeo:A 1118 34 0.0310 0.0107 0.3529 6.1
12 6x2f:A 1144 34 0.0310 0.0105 0.3529 6.2 7ssg:A, 6x26:A, 6x2n:A, 6x43:A, 6x4w:A, 6x4y:A, 6x50:A
13 8q5u:D 788 69 0.0439 0.0216 0.2464 7.4 6e58:A, 6e58:B, 6mds:A, 6mds:B, 6mdv:A, 6mdv:B, 8q5u:F, 8q5u:E
14 4dwj:B 203 31 0.0336 0.0640 0.4194 7.9 2ccg:A, 2ccg:B, 2ccj:A, 2ccj:B, 4dwj:A, 4dwj:C, 4dwj:D, 4dwj:F, 4dwj:G, 4dwj:H, 4eaq:A, 4eaq:B, 4gfd:A, 4gfd:B, 4gsy:A, 4gsy:B, 4hdc:A, 4hdc:B, 4hej:A, 4hlc:A, 4hlc:B, 4hld:A, 4hld:B, 4qg7:A, 4qg7:B, 4qga:A, 4qga:B, 4qgf:A, 4qgf:B, 4qgg:A, 4qgg:B, 4qgh:A, 4qgh:B, 4xwa:A, 4xwa:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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