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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GLYPSYNTSPAAPDSTGMQSTAVQLAGKIRLGWNIGNTMEAIGGETAWGNPMVSNELLKLVKDSGFDAVRIPVAWDQYAN
QESAEISAAWLNRVKQVVQMAIDNELYVLINIHWDGGWLENNITPAKKDENNAKQKAFWEQIATHLRDFDEHLLFAGTNE
PNAENAEQMDVLNSYLQTFVDAVRSTGGKNAYRVLVLQGPVTDIEKTNELWTHMPADTATDRLMAEVHFYTPYNFALMRQ
DESWGKQFYYWGEGFLSTTDTERNPTWGEEATIDQLFDLMKTKFVDQGIPVVLGEFSAMRRTNLTGDALTLHLAGRAYYH
KYVTQQALARGLLPFYWDNGGNDNFSSGIFNRQQNTVFDQQVLDALLEGAG

The query sequence (length=371) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8oz1:A 373 371 1.0000 0.9946 1.0000 0.0 6ha9:A, 6ha9:B, 6haa:A, 6haa:B, 5oyd:A, 5oyd:B, 5oye:A, 5oye:B
2 3zmr:A 469 384 0.3908 0.3092 0.3776 2.94e-81 3zmr:B
3 4w8b:A 386 375 0.3774 0.3627 0.3733 1.33e-73
4 2jeq:A 359 374 0.3693 0.3816 0.3663 2.06e-62
5 6wqp:B 354 373 0.3396 0.3559 0.3378 8.84e-62 6wqv:A, 6wqv:B, 6wqv:C, 6wqv:D
6 3ndz:A 345 366 0.3100 0.3333 0.3142 6.43e-60 3ndz:C, 3ndz:B, 3ndz:D
7 5h4r:A 375 388 0.3181 0.3147 0.3041 4.13e-49
8 8ghy:A 362 375 0.3019 0.3094 0.2987 1.49e-46 8ghy:B
9 3ays:A 357 380 0.3019 0.3137 0.2947 8.66e-45
10 4yhg:A 389 362 0.3046 0.2905 0.3122 2.52e-44
11 4yzt:A 512 329 0.2749 0.1992 0.3100 4.97e-44
12 6gl0:A 331 333 0.2776 0.3112 0.3093 4.53e-41 6gl0:B, 6gl0:C
13 5d9n:A 349 319 0.2722 0.2894 0.3166 7.92e-41 5d9m:A, 5d9m:B, 5d9n:B, 5d9o:A, 5d9o:B, 5d9p:A, 5d9p:B
14 4v2x:A 534 346 0.2965 0.2060 0.3179 1.08e-40
15 4w88:B 340 376 0.3019 0.3294 0.2979 3.37e-40 4w86:A, 4w86:B, 4w87:A, 4w87:B, 4w88:A, 4w89:A, 4w89:B
16 4u5k:A 304 346 0.2588 0.3158 0.2775 3.99e-26 4u5i:A, 4u5i:B, 4u5k:B
17 6ujf:A 301 352 0.2588 0.3189 0.2727 6.49e-25
18 3nco:A 313 352 0.2399 0.2843 0.2528 1.64e-19 3nco:B, 3rjy:A
19 3amg:A 311 345 0.2210 0.2637 0.2377 1.64e-16 3aof:B, 3aof:A, 3azr:A, 3azr:B, 3azs:A, 3azs:B, 3azt:A, 3azt:D, 3mmw:A, 3mmw:B, 3mmw:C, 3mmw:D
20 7vt5:A 311 285 0.1914 0.2283 0.2491 4.23e-15 7vt6:A, 7vt7:A
21 3amg:B 291 340 0.2210 0.2818 0.2412 5.26e-15
22 4w7v:A 313 130 0.0889 0.1054 0.2538 3.11e-06 4w7w:A
23 5ecu:A 350 151 0.0943 0.1000 0.2318 4.37e-04
24 3pzt:B 296 153 0.0997 0.1250 0.2418 0.006 3pzt:A
25 5d8z:A 324 150 0.0943 0.1080 0.2333 0.011 5d8z:B
26 3aiq:A 491 109 0.0647 0.0489 0.2202 0.052 3air:A, 3ais:A, 3aiv:A, 3aiw:A
27 1e5j:A 302 144 0.0943 0.1159 0.2431 0.055 2a3h:A, 3a3h:A, 4a3h:A, 5a3h:A, 6a3h:A, 8a3h:A, 1h11:A, 1h2j:A, 1h5v:A, 1hf6:A, 1ocq:A, 1qhz:A, 1qi0:A, 1qi2:A, 2v38:A, 1w3k:A, 1w3l:A
28 8ivy:A 451 104 0.0593 0.0488 0.2115 0.10 8ivy:B
29 6r2j:D 329 189 0.1024 0.1155 0.2011 0.32 6r2j:A
30 8bqa:AAA 298 96 0.0647 0.0805 0.2500 0.57
31 5ljf:A 321 51 0.0323 0.0374 0.2353 0.57 5ljf:B, 4m24:A, 7p6h:A, 7p6h:B, 7p6j:A, 7p6j:B, 7p6j:C, 7p6j:D, 6zz3:A, 6zz3:B, 6zz3:C, 6zz3:D
32 4c3s:A 435 82 0.0566 0.0483 0.2561 0.90 5dbv:A
33 2ch6:A 343 64 0.0647 0.0700 0.3750 1.1 2ch6:B, 2ch6:C, 2ch6:D
34 5w10:A 173 33 0.0377 0.0809 0.4242 1.1 5w10:B, 5w10:C, 5w10:D
35 8rwk:A 495 179 0.1213 0.0909 0.2514 1.2 8rwk:B, 8rwk:C, 8rwk:D
36 1e55:A 492 62 0.0458 0.0346 0.2742 1.5 1e1f:A, 1e1f:B, 1e4n:A, 1e4n:B, 1e55:B, 1e56:A, 1e56:B, 1h49:B, 1h49:A, 1v08:A, 1v08:B
37 6m6l:B 445 72 0.0566 0.0472 0.2917 1.5
38 3gnr:A 478 129 0.0782 0.0607 0.2248 1.7 3wba:A, 3wbe:A
39 7mix:A 1326 26 0.0323 0.0090 0.4615 2.1 7miy:A
40 3hbz:A 341 113 0.0782 0.0850 0.2566 2.5
41 6koz:A 436 79 0.0647 0.0550 0.3038 3.0 6a8z:A, 6a8z:B, 6iff:A, 6iff:B, 6ifg:A, 6ifg:B, 6koy:A, 6koy:B, 6koz:B, 6kp0:A, 6kp0:B, 6kp1:A, 6kp1:B
42 4jie:A 484 97 0.0512 0.0393 0.1959 8.3 4re2:A, 4re3:A, 4re4:A
43 2v82:A 205 63 0.0620 0.1122 0.3651 8.7

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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