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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GLTHRKFGGSGGSPFSGLSSIAVRSGSALDAIIIDGVHHGGSGGNLSPTFTFGSGEYISNMTIRSGDAIDNISFETNMGR
RFGPYGGSGGSANTLSNVKVIQINGSAGDALDSLDIYYEQY

The query sequence (length=121) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3ll2:A 123 121 0.9587 0.9431 0.9587 2.71e-76 2guc:A, 2guc:B, 2gud:A, 2gud:B, 2hyq:A, 2hyq:B, 2hyr:A, 2hyr:B, 2nuo:A, 2nuo:B, 7ria:A, 7ria:B, 7rib:A, 7rib:B, 7rib:C, 7rkg:A, 7rkg:B, 7rki:A, 7rki:B
2 6fly:A 144 121 0.2810 0.2361 0.2810 1.26e-05 6fly:B, 6flz:A, 6flz:B
3 1zgs:A 442 139 0.2975 0.0814 0.2590 3.95e-04 4mq0:A, 1zgs:B
4 1zgs:A 442 93 0.2314 0.0633 0.3011 0.017 4mq0:A, 1zgs:B
5 1zgs:A 442 65 0.1818 0.0498 0.3385 0.12 4mq0:A, 1zgs:B
6 5m6o:A 150 62 0.1736 0.1400 0.3387 5.57e-04 5m6o:B, 5m6o:C, 5m6o:D, 5tqz:A, 5tqz:B, 5tqz:C, 5tqz:D
7 1j4u:A 149 52 0.1570 0.1275 0.3654 5.63e-04 1j4u:B, 1j4u:C, 1j4u:D, 1vbo:A, 1vbo:B, 1vbo:C, 1vbo:E, 1vbo:G, 1vbo:H, 1vbo:D, 1vbo:F, 1vbp:A, 1vbp:B
8 4pit:B 144 133 0.2975 0.2500 0.2707 7.97e-04 2bmz:A, 2bmz:B, 2bn0:A, 2bn0:B, 8hyf:A, 3mit:A, 3mit:B, 3miu:A, 3miu:B, 3miv:B, 4pik:B, 4pik:C, 4pik:D, 4pik:A, 4pit:A, 4pit:C, 4pit:D, 1x1v:A, 1x1v:B
9 4pit:B 144 78 0.1818 0.1528 0.2821 8.4 2bmz:A, 2bmz:B, 2bn0:A, 2bn0:B, 8hyf:A, 3mit:A, 3mit:B, 3miu:A, 3miu:B, 3miv:B, 4pik:B, 4pik:C, 4pik:D, 4pik:A, 4pit:A, 4pit:C, 4pit:D, 1x1v:A, 1x1v:B
10 5yrf:B 142 45 0.1074 0.0915 0.2889 0.65 5yrf:A, 5yrg:A, 5yrg:B, 5yri:B, 5yri:A, 5yrj:A, 5yrj:B, 5yrl:A, 5yrl:B, 5yrm:B
11 3gd7:A 378 55 0.1570 0.0503 0.3455 1.1 3gd7:B, 3gd7:C, 3gd7:D, 6uk1:A, 6uk1:B, 6uk1:C, 6uk1:D
12 8v7z:A 1104 55 0.1570 0.0172 0.3455 1.3
13 5uak:A 1139 55 0.1570 0.0167 0.3455 1.3 2bbs:B, 7svr:A, 8v81:A
14 6msm:A 1181 55 0.1570 0.0161 0.3455 1.3 8eig:A, 8eio:A, 8eiq:A, 8fzq:A, 6gjq:A, 6gjq:C, 6gjq:E, 6gjq:G, 6gjs:A, 6gk4:A, 6gk4:D, 6gkd:A, 6gkd:L, 6gkd:F, 6gkd:I, 6gkd:O, 6gkd:R, 8gls:A, 6o1v:A, 6o2p:A, 2pze:A, 2pze:B, 2pzf:A, 2pzf:B, 2pzg:A, 2pzg:B, 7sv7:A, 7svd:A, 5tf7:A, 5tf8:A, 5tfa:A, 5tfb:A, 5tfc:A, 5tfd:A, 5tff:A, 5tfg:A, 5tfi:A, 5tfj:A, 5tgk:A, 8ubr:A, 6wbs:A, 6wbs:B, 6ze1:A
15 2vr5:A 715 87 0.2149 0.0364 0.2989 2.3 2vr5:B
16 2xq1:B 494 59 0.1488 0.0364 0.3051 5.5 2xq1:C, 2xq1:D, 2xq1:E, 2xq1:F, 2xq1:G, 2xq1:H, 2xq1:I, 2xq1:J, 2xq1:K, 2xq1:L, 2xq1:M, 2xq1:N, 2xq1:O, 2xq1:P
17 3cp0:A 63 28 0.0909 0.1746 0.3929 6.2
18 8j5q:D 611 32 0.1157 0.0229 0.4375 7.2 8j5r:D, 8j5s:D, 8j5t:D
19 7p18:A 558 40 0.1240 0.0269 0.3750 7.4 7p18:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218