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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GLPWYRVHTVVLNDPGRLLSVHLMHTALVSGWAGSMALYELAKYDPSDPVLNPMWRQGTFVMPVMTRIGVTHSWSGWTVT
GEPWVTQPGILGAHLNFFSYEGVILMHILAAGLFFLAAVWHWINWDLDIYYPDGSSEPASDWPKIFGLHLLTLGIVCFGF
GSLHLTGILGPGMWVSDPYGLTGHVQGVSPDWRPFAFDPYNPTGLVTHHISAGIALIIGGIFHTVSRPSERLYNALSMGN
VETVLSSSVAFVAAAAFVMVGTMWYGSATTPIELFGPTRYQWDSGYFQTEIQRRVQSGQTWDQIPEKLVFYDYIGNSPAK
GGLFRTGAMNSGDGIARAWEGHPTFTDSEGRELFVRRMPNFFETFPVVLTDKDGVVRADIPFRRAESRYSFEQKGVSVSF
EGGTLNGQTFTDAPSVKKYARKAQLGEPFEFDRETLGSDGVFRTSTRGWFAFSHSCYALLFFFGHWWHGARTIFKDVFE

The query sequence (length=479) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ymi:B 479 479 1.0000 1.0000 1.0000 0.0 7ymi:b, 7ymm:1B, 7ymm:2B, 7ymm:3B, 7ymm:4B
2 8wql:b1 504 486 0.7223 0.6865 0.7119 0.0 8wql:BD, 8wql:BE, 8wql:B1, 8wql:bD, 8wql:bE
3 7y5e:BL 506 486 0.6910 0.6542 0.6811 0.0 8iwh:B, 8iwh:b, 6j3y:B, 6j3y:b, 6j3z:B, 6j3z:b, 6j40:B, 6j40:b, 8j5k:B, 8j5k:b, 6jlu:B, 6jlu:b, 7vd5:B, 7vd5:b, 8wb4:b, 8wb4:B, 8xlp:b, 8xlp:B, 8xr6:B, 8xr6:b, 7y5e:b6, 7y5e:B6, 7y5e:bL, 7y7a:BO, 7y7a:B9, 7y7a:bZ, 7y7a:b9, 7y7a:bE, 7y7a:BE, 7y7a:Bm, 7y7a:bO, 7y7a:BZ, 7y7a:bm
4 5v2c:b 506 486 0.7035 0.6660 0.6934 0.0 3a0b:B, 3a0b:b, 3a0h:B, 3a0h:b, 2axt:B, 2axt:b, 5b5e:B, 5b5e:b, 5b66:B, 5b66:b, 7cji:B, 7cji:b, 7cjj:B, 7cjj:b, 7cou:B, 7cou:b, 7czl:B, 7czl:b, 7d1t:B, 7d1t:b, 7d1u:B, 7d1u:b, 6dhe:B, 6dhe:b, 6dhf:B, 6dhf:b, 6dhg:B, 6dhg:b, 6dhh:B, 6dhh:b, 6dho:B, 6dho:b, 6dhp:B, 6dhp:b, 7dxa:b, 7dxh:b, 5e79:B, 5e79:b, 5e7c:B, 5e7c:b, 7eda:B, 9evx:B, 9evx:b, 8ez5:B, 8ez5:b, 8f4c:B, 8f4c:b, 8f4d:B, 8f4d:b, 8f4e:B, 8f4e:b, 8f4f:B, 8f4f:b, 8f4g:B, 8f4g:b, 8f4h:B, 8f4h:b, 8f4i:B, 8f4i:b, 8f4j:B, 8f4j:b, 8f4k:B, 8f4k:b, 4fby:B, 4fby:N, 8gn0:B, 8gn0:b, 8gn1:B, 8gn1:b, 8gn2:B, 8gn2:b, 5gth:B, 5gth:b, 5gti:B, 5gti:b, 5h2f:B, 5h2f:b, 4il6:B, 4il6:b, 8ir5:B, 8ir5:b, 8ir6:B, 8ir6:b, 8ir7:B, 8ir7:b, 8ir8:B, 8ir8:b, 8ir9:B, 8ir9:b, 8ira:B, 8ira:b, 8irb:B, 8irb:b, 8irc:B, 8irc:b, 8ird:B, 8ird:b, 8ire:B, 8ire:b, 8irf:B, 8irf:b, 8irg:B, 8irg:b, 8irh:B, 8irh:b, 8iri:B, 8iri:b, 4ixq:B, 4ixq:b, 4ixr:B, 4ixr:b, 6jlj:B, 6jlj:b, 6jlk:B, 6jlk:b, 6jll:B, 6jll:b, 6jlm:B, 6jlm:b, 6jln:B, 6jln:b, 6jlo:B, 6jlo:b, 6jlp:B, 6jlp:b, 5kaf:B, 5kaf:b, 5kai:B, 5kai:b, 3kzi:B, 5mx2:B, 5mx2:b, 7nho:B, 7nhp:B, 7nhq:B, 4pbu:B, 4pbu:b, 4pj0:B, 4pj0:b, 7rf1:B, 7rf1:b, 7rf2:B, 7rf2:b, 7rf3:B, 7rf3:b, 7rf4:B, 7rf4:b, 7rf5:B, 7rf5:b, 7rf6:B, 7rf6:b, 7rf7:B, 7rf7:b, 7rf8:B, 7rf8:b, 4rvy:B, 4rvy:b, 1s5l:B, 1s5l:b, 5tis:B, 5tis:b, 4tnh:B, 4tnh:b, 4tni:B, 4tni:b, 4tnj:B, 4tnj:b, 4tnk:B, 4tnk:b, 4ub6:B, 4ub6:b, 4ub8:B, 4ub8:b, 5v2c:B, 4v62:AB, 4v62:BB, 4v82:AB, 4v82:BB, 6w1o:B, 6w1o:b, 6w1p:B, 6w1p:b, 6w1q:B, 6w1q:b, 6w1r:B, 6w1r:b, 6w1t:B, 6w1t:b, 6w1u:B, 6w1u:b, 6w1v:B, 6w1v:b, 1w5c:B, 1w5c:H, 5ws5:B, 5ws5:b, 5ws6:B, 5ws6:b, 3wu2:B, 3wu2:b, 7yq2:B, 7yq2:b, 7yq7:B, 7yq7:b, 5zzn:B, 5zzn:b
5 8bd3:B 504 486 0.6931 0.6587 0.6831 0.0 8bd3:b
6 6kaf:B 503 486 0.6952 0.6620 0.6852 0.0 6kac:B, 6kac:b, 6kad:B, 6kad:b, 6kaf:b, 8kde:B, 7pi0:B, 7pi0:b, 7pi5:B, 7pi5:b, 7pin:B, 7pin:b, 7pin:B1, 7pin:b1, 7piw:B, 7piw:b, 7piw:B1, 7piw:b1, 7pnk:B, 7pnk:b, 8r2i:B, 8zee:B
7 8tow:B 506 486 0.7035 0.6660 0.6934 0.0 7n8o:B, 7n8o:b, 7rcv:B, 7rcv:b, 8tow:b, 6wj6:B
8 4yuu:b1 503 485 0.6681 0.6362 0.6598 0.0 4yuu:B1, 4yuu:B2, 4yuu:b2
9 5xnl:B 503 486 0.6785 0.6461 0.6687 0.0 8c29:B, 8c29:b, 3jcu:B, 3jcu:b, 5mdx:b, 5mdx:B, 7oui:B, 7oui:b, 5xnl:b, 5xnm:B, 5xnm:b, 6yp7:b, 6yp7:B
10 8eqm:B 483 487 0.6326 0.6273 0.6222 0.0 8eqm:b
11 7sa3:B 450 482 0.6054 0.6444 0.6017 0.0
12 1izl:B 427 265 0.3466 0.3888 0.6264 1.95e-105 1izl:L
13 1izl:B 427 73 0.1148 0.1288 0.7534 1.81e-29 1izl:L
14 8wql:c1 453 505 0.2422 0.2561 0.2297 2.18e-16 8wql:CD, 8wql:CE, 8wql:C1, 8wql:cD, 8wql:cE
15 8wb4:C 451 315 0.1712 0.1818 0.2603 3.41e-16 8wb4:c, 8xlp:c, 8xlp:C, 8xr6:c, 8xr6:C
16 5v2c:c 458 492 0.2401 0.2511 0.2337 5.91e-16 3a0b:C, 3a0b:c, 3a0h:C, 3a0h:c, 2axt:C, 2axt:c, 5b5e:C, 5b5e:c, 5b66:C, 5b66:c, 7cji:C, 7cji:c, 7cjj:C, 7cjj:c, 7cou:C, 7cou:c, 7czl:C, 7czl:c, 7d1t:C, 7d1t:c, 7d1u:C, 7d1u:c, 6dhe:C, 6dhe:c, 6dhf:C, 6dhf:c, 6dhg:C, 6dhg:c, 6dhh:C, 6dhh:c, 6dho:C, 6dho:c, 6dhp:C, 6dhp:c, 7dxh:c, 5e79:C, 5e79:c, 5e7c:C, 5e7c:c, 7eda:C, 9evx:C, 9evx:c, 8ez5:C, 8ez5:c, 8f4c:C, 8f4c:c, 8f4d:C, 8f4d:c, 8f4e:C, 8f4e:c, 8f4f:C, 8f4f:c, 8f4g:C, 8f4g:c, 8f4h:C, 8f4h:c, 8f4i:C, 8f4i:c, 8f4j:C, 8f4j:c, 8f4k:C, 8f4k:c, 4fby:C, 4fby:P, 8gn0:C, 8gn0:c, 8gn1:C, 8gn1:c, 8gn2:C, 8gn2:c, 5gth:C, 5gth:c, 5gti:C, 5gti:c, 5h2f:C, 5h2f:c, 4il6:C, 4il6:c, 8ir5:C, 8ir5:c, 8ir6:C, 8ir6:c, 8ir7:C, 8ir7:c, 8ir8:C, 8ir8:c, 8ir9:C, 8ir9:c, 8ira:C, 8ira:c, 8irb:C, 8irb:c, 8irc:C, 8irc:c, 8ird:C, 8ird:c, 8ire:C, 8ire:c, 8irf:C, 8irf:c, 8irg:C, 8irg:c, 8irh:C, 8irh:c, 8iri:C, 8iri:c, 4ixq:C, 4ixq:c, 4ixr:C, 4ixr:c, 6jlj:C, 6jlj:c, 6jlk:C, 6jlk:c, 6jll:C, 6jll:c, 6jlm:C, 6jlm:c, 6jln:C, 6jln:c, 6jlo:C, 6jlo:c, 6jlp:C, 6jlp:c, 5kaf:C, 5kaf:c, 5kai:C, 5kai:c, 3kzi:C, 5mx2:C, 5mx2:c, 7nho:C, 7nhp:C, 7nhq:C, 4pbu:C, 4pbu:c, 4pj0:C, 4pj0:c, 7rf1:C, 7rf1:c, 7rf2:C, 7rf2:c, 7rf3:C, 7rf3:c, 7rf4:C, 7rf4:c, 7rf5:C, 7rf5:c, 7rf6:C, 7rf6:c, 7rf7:C, 7rf7:c, 7rf8:C, 7rf8:c, 4rvy:C, 4rvy:c, 1s5l:C, 1s5l:c, 5tis:C, 5tis:c, 4tnh:C, 4tnh:c, 4tni:C, 4tni:c, 4tnj:C, 4tnj:c, 4tnk:C, 4tnk:c, 4ub6:C, 4ub6:c, 4ub8:C, 4ub8:c, 5v2c:C, 4v62:AC, 4v62:BC, 4v82:AC, 4v82:BC, 6w1o:C, 6w1o:c, 6w1p:C, 6w1p:c, 6w1q:C, 6w1q:c, 6w1r:C, 6w1r:c, 6w1t:C, 6w1t:c, 6w1u:C, 6w1u:c, 6w1v:C, 6w1v:c, 1w5c:C, 1w5c:I, 5ws5:C, 5ws5:c, 5ws6:C, 5ws6:c, 3wu2:C, 3wu2:c, 7yq2:C, 7yq2:c, 7yq7:C, 7yq7:c, 5zzn:C, 5zzn:c
17 4yuu:C1 449 312 0.1608 0.1715 0.2468 9.85e-15 4yuu:c1, 4yuu:C2, 4yuu:c2
18 8eqm:C 453 283 0.1608 0.1700 0.2721 1.10e-14 8eqm:c, 7sa3:C
19 7n8o:C 450 505 0.2443 0.2600 0.2317 2.00e-14 7n8o:c, 7rcv:C, 7rcv:c, 8tow:C, 8tow:c
20 5xnl:C 450 489 0.2276 0.2422 0.2229 5.25e-14 8c29:C, 8c29:c, 3jcu:C, 3jcu:c, 5mdx:C, 5mdx:c, 7oui:C, 7oui:c, 5xnl:c, 5xnm:C, 5xnm:c, 6yp7:c, 6yp7:C
21 6kaf:C 450 487 0.2276 0.2422 0.2238 1.04e-13 8bd3:C, 8bd3:c, 6kac:C, 6kac:c, 6kad:C, 6kad:c, 6kaf:c, 7pi0:C, 7pi0:c, 7pi5:C, 7pi5:c, 7pin:C, 7pin:c, 7pin:C1, 7pin:c1, 7piw:C, 7piw:c, 7piw:C1, 7piw:c1, 7pnk:C, 7pnk:c, 8r2i:C
22 6wj6:C 415 312 0.1566 0.1807 0.2404 2.49e-13
23 6j3y:C 451 497 0.2296 0.2439 0.2213 6.44e-13 8iwh:C, 8iwh:c, 6j3y:c, 6j3z:C, 6j3z:c, 6j40:C, 6j40:c, 8j5k:C, 8j5k:c, 6jlu:C, 6jlu:c, 7vd5:C, 7vd5:c
24 7ymi:C 420 335 0.1566 0.1786 0.2239 1.89e-12 7ymi:c, 7ymm:1C, 7ymm:2C, 7ymm:3C, 7ymm:4C
25 7ymi:C 420 25 0.0271 0.0310 0.5200 0.67 7ymi:c, 7ymm:1C, 7ymm:2C, 7ymm:3C, 7ymm:4C
26 7y5e:CL 452 303 0.1524 0.1615 0.2409 1.29e-11 7y5e:C6, 7y5e:c6, 7y5e:cL, 7y7a:C9, 7y7a:c9, 7y7a:CE, 7y7a:cE, 7y7a:CO, 7y7a:cO, 7y7a:CZ, 7y7a:cZ, 7y7a:Cm, 7y7a:cm
27 8kde:C 430 296 0.1482 0.1651 0.2399 1.81e-11 8zee:C
28 1izl:C 349 266 0.1420 0.1948 0.2556 9.13e-10 1izl:M
29 6k33:a4 336 291 0.1566 0.2232 0.2577 7.31e-09 6k33:a1, 6k33:c6, 6k33:a2, 6k33:a3, 6k33:a5, 6k33:a6, 6k33:b1, 6k33:b2, 6k33:b3, 6k33:b4, 6k33:b5, 6k33:b6, 6k33:c1, 6k33:c2, 6k33:c3, 6k33:c4, 6k33:c5
30 7y3f:5 332 286 0.1461 0.2108 0.2448 1.13e-08 7y3f:4
31 7y3f:1 466 66 0.0501 0.0515 0.3636 1.39e-07
32 7y3f:1 466 28 0.0271 0.0279 0.4643 1.6
33 7ymi:2 349 300 0.1441 0.1977 0.2300 2.92e-06 7ymi:6, 7ymm:12, 7ymm:22, 7ymm:32, 7ymm:42
34 7ymi:7 344 284 0.1503 0.2093 0.2535 6.24e-05 7ymi:3, 7ymm:23, 7ymm:13, 7ymm:43, 7ymm:33
35 6nwa:Y 340 286 0.1399 0.1971 0.2343 2.67e-04 6nwa:W, 6nwa:X, 6nwa:Z, 6nwa:g, 6nwa:h, 6nwa:y, 6nwa:n, 6nwa:o, 6nwa:p, 6nwa:q, 6nwa:r, 6nwa:v, 6nwa:t, 6nwa:u, 6nwa:s, 6nwa:w, 6nwa:x, 7umh:W, 7umh:X, 7umh:Y, 7umh:Z, 7umh:g, 7umh:h, 7umh:n, 7umh:o, 7umh:p, 7umh:q, 7umh:r, 7umh:v, 7umh:s, 7umh:w, 7umh:t, 7umh:u, 7umh:x, 7umh:y
36 6kif:1 339 293 0.1336 0.1888 0.2184 0.001 6kif:v, 6kif:2, 6kif:3, 6kif:4, 6kif:5, 6kif:6, 6kif:Y, 6kif:Z, 6kif:a, 6kif:b, 6kif:c, 6kif:d, 6kif:q, 6kif:r, 6kif:s, 6kif:t, 6kif:u, 6kig:4, 6kig:1, 6kig:v, 6kig:2, 6kig:3, 6kig:5, 6kig:6, 6kig:b, 6kig:Y, 6kig:Z, 6kig:a, 6kig:c, 6kig:d, 6kig:t, 6kig:q, 6kig:r, 6kig:s, 6kig:u
37 7ymi:4 331 289 0.1545 0.2236 0.2561 0.003 7ymi:8, 7ymm:14, 7ymm:24, 7ymm:34, 7ymm:44
38 7ymi:1 329 307 0.1524 0.2219 0.2378 0.016 7ymi:5, 7ymm:11, 7ymm:21, 7ymm:31, 7ymm:41
39 6b6w:B 628 69 0.0543 0.0414 0.3768 1.3 6b6v:A, 6b6v:B, 6b6w:A, 6b6x:A, 6b6x:B, 6b6y:A, 6b6y:B, 6dc2:A, 6dc2:B, 6dc2:C, 6dc2:D, 6onc:A, 6onc:B, 6onc:C, 6onc:D, 6ond:A, 6ond:B, 6ond:C, 6ond:D, 6ons:A, 7tsj:A, 6vwy:A, 6vwy:B, 6vwz:A, 6vwz:B, 6vx0:A, 6vx0:B, 6vx1:A, 6vx1:B
40 5v8k:A 600 122 0.0710 0.0567 0.2787 1.5
41 8gy2:A 723 18 0.0230 0.0152 0.6111 6.3
42 1oao:C 729 43 0.0334 0.0219 0.3721 9.7 3git:A, 3git:B, 3git:C, 3git:D, 3git:E, 3git:F, 3i01:M, 3i01:N, 3i01:O, 3i01:P, 3i04:M, 3i04:N, 3i04:O, 3i04:P, 1mjg:M, 1mjg:N, 1mjg:O, 1mjg:P, 1oao:D, 6x5k:M, 6x5k:N, 6x5k:O, 6x5k:P, 2z8y:M, 2z8y:N, 2z8y:O, 2z8y:P

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218