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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GLPWYRVHTSVLNDPGRLIAVHIMHNALCAGFAGSMLLFELALFDPSDPVLNPMWRQGCFLMPFVSRLGVVNSWQGWSVT
GETFTNPGFWTFETVAIAHIIFSGLSFLAACWHWVYWDVATFFDPKTDEPVIDLPKVFGIHLTLAGILCFGFGAFHLTGL
FGPGMWVSDPLGLTGHIQGVAPEWGAAGFDPHNPGGVVAHHIALGIVAIIGGLFHIFVRPPEYLYKGLRMGNIEGTLASG
LAVFFSGAFIAAGTMWYGTATTPIELWGPTRYQWDQGFFQQAISRQVKASISDGKSPSEAWSEIPTKLAFYDYIGNSPAK
GGLFRVGRMVDGDGLPTGWLGHPVFKDGEGRELTVRRMPNFFENFPVVLFDQDGIVRADIPFRQAESKYGIEQTGVTVSF
YGGELDGQTFSDPKDVKKYARRAQLGEPFEFDRSVYDSDGLFRTSNRGFFAFFHVIFGLLWFFGHIWHGLRALFQDVFSG
IDP

The query sequence (length=483) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8eqm:B 483 483 1.0000 1.0000 1.0000 0.0 8eqm:b
2 7sa3:B 450 474 0.9317 1.0000 0.9494 0.0
3 8bd3:B 504 482 0.6936 0.6647 0.6950 0.0 8bd3:b
4 8tow:B 506 483 0.7164 0.6838 0.7164 0.0 7n8o:B, 7n8o:b, 7rcv:B, 7rcv:b, 8tow:b, 6wj6:B
5 8wql:b1 504 482 0.7226 0.6925 0.7241 0.0 8wql:BD, 8wql:BE, 8wql:B1, 8wql:bD, 8wql:bE
6 7y5e:BL 506 481 0.6998 0.6680 0.7027 0.0 8iwh:B, 8iwh:b, 6j3y:B, 6j3y:b, 6j3z:B, 6j3z:b, 6j40:B, 6j40:b, 8j5k:B, 8j5k:b, 6jlu:B, 6jlu:b, 7vd5:B, 7vd5:b, 8wb4:b, 8wb4:B, 8xlp:b, 8xlp:B, 8xr6:B, 8xr6:b, 7y5e:b6, 7y5e:B6, 7y5e:bL, 7y7a:BO, 7y7a:B9, 7y7a:bZ, 7y7a:b9, 7y7a:bE, 7y7a:BE, 7y7a:Bm, 7y7a:bO, 7y7a:BZ, 7y7a:bm
7 5v2c:b 506 483 0.7143 0.6818 0.7143 0.0 3a0b:B, 3a0b:b, 3a0h:B, 3a0h:b, 2axt:B, 2axt:b, 5b5e:B, 5b5e:b, 5b66:B, 5b66:b, 7cji:B, 7cji:b, 7cjj:B, 7cjj:b, 7cou:B, 7cou:b, 7czl:B, 7czl:b, 7d1t:B, 7d1t:b, 7d1u:B, 7d1u:b, 6dhe:B, 6dhe:b, 6dhf:B, 6dhf:b, 6dhg:B, 6dhg:b, 6dhh:B, 6dhh:b, 6dho:B, 6dho:b, 6dhp:B, 6dhp:b, 7dxa:b, 7dxh:b, 5e79:B, 5e79:b, 5e7c:B, 5e7c:b, 7eda:B, 9evx:B, 9evx:b, 8ez5:B, 8ez5:b, 8f4c:B, 8f4c:b, 8f4d:B, 8f4d:b, 8f4e:B, 8f4e:b, 8f4f:B, 8f4f:b, 8f4g:B, 8f4g:b, 8f4h:B, 8f4h:b, 8f4i:B, 8f4i:b, 8f4j:B, 8f4j:b, 8f4k:B, 8f4k:b, 4fby:B, 4fby:N, 8gn0:B, 8gn0:b, 8gn1:B, 8gn1:b, 8gn2:B, 8gn2:b, 5gth:B, 5gth:b, 5gti:B, 5gti:b, 5h2f:B, 5h2f:b, 4il6:B, 4il6:b, 8ir5:B, 8ir5:b, 8ir6:B, 8ir6:b, 8ir7:B, 8ir7:b, 8ir8:B, 8ir8:b, 8ir9:B, 8ir9:b, 8ira:B, 8ira:b, 8irb:B, 8irb:b, 8irc:B, 8irc:b, 8ird:B, 8ird:b, 8ire:B, 8ire:b, 8irf:B, 8irf:b, 8irg:B, 8irg:b, 8irh:B, 8irh:b, 8iri:B, 8iri:b, 4ixq:B, 4ixq:b, 4ixr:B, 4ixr:b, 6jlj:B, 6jlj:b, 6jlk:B, 6jlk:b, 6jll:B, 6jll:b, 6jlm:B, 6jlm:b, 6jln:B, 6jln:b, 6jlo:B, 6jlo:b, 6jlp:B, 6jlp:b, 5kaf:B, 5kaf:b, 5kai:B, 5kai:b, 3kzi:B, 5mx2:B, 5mx2:b, 7nho:B, 7nhp:B, 7nhq:B, 4pbu:B, 4pbu:b, 4pj0:B, 4pj0:b, 7rf1:B, 7rf1:b, 7rf2:B, 7rf2:b, 7rf3:B, 7rf3:b, 7rf4:B, 7rf4:b, 7rf5:B, 7rf5:b, 7rf6:B, 7rf6:b, 7rf7:B, 7rf7:b, 7rf8:B, 7rf8:b, 4rvy:B, 4rvy:b, 1s5l:B, 1s5l:b, 5tis:B, 5tis:b, 4tnh:B, 4tnh:b, 4tni:B, 4tni:b, 4tnj:B, 4tnj:b, 4tnk:B, 4tnk:b, 4ub6:B, 4ub6:b, 4ub8:B, 4ub8:b, 5v2c:B, 4v62:AB, 4v62:BB, 4v82:AB, 4v82:BB, 6w1o:B, 6w1o:b, 6w1p:B, 6w1p:b, 6w1q:B, 6w1q:b, 6w1r:B, 6w1r:b, 6w1t:B, 6w1t:b, 6w1u:B, 6w1u:b, 6w1v:B, 6w1v:b, 1w5c:B, 1w5c:H, 5ws5:B, 5ws5:b, 5ws6:B, 5ws6:b, 3wu2:B, 3wu2:b, 7yq2:B, 7yq2:b, 7yq7:B, 7yq7:b, 5zzn:B, 5zzn:b
8 6kaf:B 503 482 0.6874 0.6600 0.6888 0.0 6kac:B, 6kac:b, 6kad:B, 6kad:b, 6kaf:b, 8kde:B, 7pi0:B, 7pi0:b, 7pi5:B, 7pi5:b, 7pin:B, 7pin:b, 7pin:B1, 7pin:b1, 7piw:B, 7piw:b, 7piw:B1, 7piw:b1, 7pnk:B, 7pnk:b, 8r2i:B, 8zee:B
9 4yuu:b1 503 481 0.6770 0.6501 0.6798 0.0 4yuu:B1, 4yuu:B2, 4yuu:b2
10 5xnl:B 503 483 0.6957 0.6680 0.6957 0.0 8c29:B, 8c29:b, 3jcu:B, 3jcu:b, 5mdx:b, 5mdx:B, 7oui:B, 7oui:b, 5xnl:b, 5xnm:B, 5xnm:b, 6yp7:b, 6yp7:B
11 7ymi:B 479 487 0.6273 0.6326 0.6222 0.0 7ymi:b, 7ymm:1B, 7ymm:2B, 7ymm:3B, 7ymm:4B
12 1izl:B 427 257 0.3768 0.4262 0.7082 4.62e-120 1izl:L
13 1izl:B 427 74 0.0994 0.1124 0.6486 6.21e-24 1izl:L
14 8wb4:C 451 331 0.1760 0.1885 0.2568 9.38e-17 8wb4:c, 8xlp:c, 8xlp:C, 8xr6:c, 8xr6:C
15 8eqm:C 453 313 0.1739 0.1854 0.2684 9.72e-17 8eqm:c, 7sa3:C
16 8eqm:C 453 55 0.0290 0.0309 0.2545 6.2 8eqm:c, 7sa3:C
17 8wql:c1 453 322 0.1698 0.1810 0.2547 1.65e-16 8wql:CD, 8wql:CE, 8wql:C1, 8wql:cD, 8wql:cE
18 7n8o:C 450 490 0.2381 0.2556 0.2347 1.69e-16 7n8o:c, 7rcv:C, 7rcv:c, 8tow:C, 8tow:c
19 6wj6:C 415 339 0.1884 0.2193 0.2684 1.11e-15
20 6j3y:C 451 327 0.1781 0.1907 0.2630 2.40e-15 8iwh:C, 8iwh:c, 6j3y:c, 6j3z:C, 6j3z:c, 6j40:C, 6j40:c, 8j5k:C, 8j5k:c, 6jlu:C, 6jlu:c, 7vd5:C, 7vd5:c
21 7ymi:C 420 302 0.1615 0.1857 0.2583 7.56e-15 7ymi:c, 7ymm:1C, 7ymm:2C, 7ymm:3C, 7ymm:4C
22 5xnl:C 450 329 0.1739 0.1867 0.2553 1.45e-14 8c29:C, 8c29:c, 3jcu:C, 3jcu:c, 5mdx:C, 5mdx:c, 7oui:C, 7oui:c, 5xnl:c, 5xnm:C, 5xnm:c, 6yp7:c, 6yp7:C
23 5v2c:c 458 324 0.1760 0.1856 0.2623 2.47e-14 3a0b:C, 3a0b:c, 3a0h:C, 3a0h:c, 2axt:C, 2axt:c, 5b5e:C, 5b5e:c, 5b66:C, 5b66:c, 7cji:C, 7cji:c, 7cjj:C, 7cjj:c, 7cou:C, 7cou:c, 7czl:C, 7czl:c, 7d1t:C, 7d1t:c, 7d1u:C, 7d1u:c, 6dhe:C, 6dhe:c, 6dhf:C, 6dhf:c, 6dhg:C, 6dhg:c, 6dhh:C, 6dhh:c, 6dho:C, 6dho:c, 6dhp:C, 6dhp:c, 7dxh:c, 5e79:C, 5e79:c, 5e7c:C, 5e7c:c, 7eda:C, 9evx:C, 9evx:c, 8ez5:C, 8ez5:c, 8f4c:C, 8f4c:c, 8f4d:C, 8f4d:c, 8f4e:C, 8f4e:c, 8f4f:C, 8f4f:c, 8f4g:C, 8f4g:c, 8f4h:C, 8f4h:c, 8f4i:C, 8f4i:c, 8f4j:C, 8f4j:c, 8f4k:C, 8f4k:c, 4fby:C, 4fby:P, 8gn0:C, 8gn0:c, 8gn1:C, 8gn1:c, 8gn2:C, 8gn2:c, 5gth:C, 5gth:c, 5gti:C, 5gti:c, 5h2f:C, 5h2f:c, 4il6:C, 4il6:c, 8ir5:C, 8ir5:c, 8ir6:C, 8ir6:c, 8ir7:C, 8ir7:c, 8ir8:C, 8ir8:c, 8ir9:C, 8ir9:c, 8ira:C, 8ira:c, 8irb:C, 8irb:c, 8irc:C, 8irc:c, 8ird:C, 8ird:c, 8ire:C, 8ire:c, 8irf:C, 8irf:c, 8irg:C, 8irg:c, 8irh:C, 8irh:c, 8iri:C, 8iri:c, 4ixq:C, 4ixq:c, 4ixr:C, 4ixr:c, 6jlj:C, 6jlj:c, 6jlk:C, 6jlk:c, 6jll:C, 6jll:c, 6jlm:C, 6jlm:c, 6jln:C, 6jln:c, 6jlo:C, 6jlo:c, 6jlp:C, 6jlp:c, 5kaf:C, 5kaf:c, 5kai:C, 5kai:c, 3kzi:C, 5mx2:C, 5mx2:c, 7nho:C, 7nhp:C, 7nhq:C, 4pbu:C, 4pbu:c, 4pj0:C, 4pj0:c, 7rf1:C, 7rf1:c, 7rf2:C, 7rf2:c, 7rf3:C, 7rf3:c, 7rf4:C, 7rf4:c, 7rf5:C, 7rf5:c, 7rf6:C, 7rf6:c, 7rf7:C, 7rf7:c, 7rf8:C, 7rf8:c, 4rvy:C, 4rvy:c, 1s5l:C, 1s5l:c, 5tis:C, 5tis:c, 4tnh:C, 4tnh:c, 4tni:C, 4tni:c, 4tnj:C, 4tnj:c, 4tnk:C, 4tnk:c, 4ub6:C, 4ub6:c, 4ub8:C, 4ub8:c, 5v2c:C, 4v62:AC, 4v62:BC, 4v82:AC, 4v82:BC, 6w1o:C, 6w1o:c, 6w1p:C, 6w1p:c, 6w1q:C, 6w1q:c, 6w1r:C, 6w1r:c, 6w1t:C, 6w1t:c, 6w1u:C, 6w1u:c, 6w1v:C, 6w1v:c, 1w5c:C, 1w5c:I, 5ws5:C, 5ws5:c, 5ws6:C, 5ws6:c, 3wu2:C, 3wu2:c, 7yq2:C, 7yq2:c, 7yq7:C, 7yq7:c, 5zzn:C, 5zzn:c
24 4yuu:C1 449 332 0.1739 0.1871 0.2530 2.75e-13 4yuu:c1, 4yuu:C2, 4yuu:c2
25 6kaf:C 450 325 0.1594 0.1711 0.2369 4.36e-12 8bd3:C, 8bd3:c, 6kac:C, 6kac:c, 6kad:C, 6kad:c, 6kaf:c, 7pi0:C, 7pi0:c, 7pi5:C, 7pi5:c, 7pin:C, 7pin:c, 7pin:C1, 7pin:c1, 7piw:C, 7piw:c, 7piw:C1, 7piw:c1, 7pnk:C, 7pnk:c, 8r2i:C
26 8kde:C 430 295 0.1511 0.1698 0.2475 2.47e-11 8zee:C
27 1izl:C 349 257 0.1449 0.2006 0.2724 1.25e-08 1izl:M
28 7y3f:1 466 298 0.1573 0.1631 0.2550 1.31e-07
29 7ymi:1 329 336 0.2029 0.2979 0.2917 1.54e-07 7ymi:5, 7ymm:11, 7ymm:21, 7ymm:31, 7ymm:41
30 7y5e:CL 452 69 0.0455 0.0487 0.3188 2.25e-05 7y5e:C6, 7y5e:c6, 7y5e:cL, 7y7a:C9, 7y7a:c9, 7y7a:CE, 7y7a:cE, 7y7a:CO, 7y7a:cO, 7y7a:CZ, 7y7a:cZ, 7y7a:Cm, 7y7a:cm
31 6nwa:Y 340 66 0.0476 0.0676 0.3485 5.23e-04 6nwa:W, 6nwa:X, 6nwa:Z, 6nwa:g, 6nwa:h, 6nwa:y, 6nwa:n, 6nwa:o, 6nwa:p, 6nwa:q, 6nwa:r, 6nwa:v, 6nwa:t, 6nwa:u, 6nwa:s, 6nwa:w, 6nwa:x, 7umh:W, 7umh:X, 7umh:Y, 7umh:Z, 7umh:g, 7umh:h, 7umh:n, 7umh:o, 7umh:p, 7umh:q, 7umh:r, 7umh:v, 7umh:s, 7umh:w, 7umh:t, 7umh:u, 7umh:x, 7umh:y
32 7ymi:4 331 247 0.1139 0.1662 0.2227 5.59e-04 7ymi:8, 7ymm:14, 7ymm:24, 7ymm:34, 7ymm:44
33 7ymi:2 349 294 0.1470 0.2034 0.2415 5.67e-04 7ymi:6, 7ymm:12, 7ymm:22, 7ymm:32, 7ymm:42
34 7y3f:5 332 290 0.1387 0.2018 0.2310 6.46e-04 7y3f:4
35 7ymi:7 344 300 0.1449 0.2035 0.2333 0.002 7ymi:3, 7ymm:23, 7ymm:13, 7ymm:43, 7ymm:33
36 6k33:a4 336 66 0.0435 0.0625 0.3182 0.007 6k33:a1, 6k33:c6, 6k33:a2, 6k33:a3, 6k33:a5, 6k33:a6, 6k33:b1, 6k33:b2, 6k33:b3, 6k33:b4, 6k33:b5, 6k33:b6, 6k33:c1, 6k33:c2, 6k33:c3, 6k33:c4, 6k33:c5
37 6kif:1 339 285 0.1491 0.2124 0.2526 0.086 6kif:v, 6kif:2, 6kif:3, 6kif:4, 6kif:5, 6kif:6, 6kif:Y, 6kif:Z, 6kif:a, 6kif:b, 6kif:c, 6kif:d, 6kif:q, 6kif:r, 6kif:s, 6kif:t, 6kif:u, 6kig:4, 6kig:1, 6kig:v, 6kig:2, 6kig:3, 6kig:5, 6kig:6, 6kig:b, 6kig:Y, 6kig:Z, 6kig:a, 6kig:c, 6kig:d, 6kig:t, 6kig:q, 6kig:r, 6kig:s, 6kig:u
38 7f4v:aA 772 114 0.0642 0.0402 0.2719 1.1 7f4v:bA, 7f4v:cA
39 3nyc:A 381 89 0.0538 0.0682 0.2921 1.3 3nye:A, 3nyf:A, 6p9d:A, 6pld:A, 7rdf:A, 3sm8:A
40 4b65:A 456 29 0.0269 0.0285 0.4483 2.4 4b63:A, 4b64:A, 4b66:A, 4b67:A, 4b68:A, 4b69:A, 5cku:A, 7jvk:A, 7jvk:B, 7jvk:C, 7jvk:D, 7jvl:A, 7jvl:B, 7jvl:C, 7jvl:D, 4nzh:A, 6x0h:A, 6x0h:B, 6x0h:C, 6x0h:D, 6x0i:A, 6x0i:B, 6x0i:C, 6x0i:D, 6x0j:A, 6x0j:B, 6x0j:C, 6x0j:D, 6x0k:A, 6x0k:B, 6x0k:C, 6x0k:D, 6x0k:E, 6x0k:F, 6x0k:G, 6x0k:H
41 8jjr:a 665 124 0.0704 0.0511 0.2742 5.5
42 4u33:A 661 152 0.0725 0.0530 0.2303 7.9 4u33:B, 4u33:C, 4u33:D, 4u33:E, 4u33:F, 4u3c:A, 4u3c:B, 4u3c:C, 4u3c:D, 4u3c:E, 4u3c:F
43 8gwa:A 667 87 0.0518 0.0375 0.2874 9.6 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
44 4pos:J 274 69 0.0435 0.0766 0.3043 9.7 4por:B, 4por:A, 4por:C, 4por:D, 4por:E, 4por:F, 4por:H, 4por:G, 4por:I, 4por:J, 4pos:B, 4pos:A, 4pos:C, 4pos:E, 4pos:D, 4pos:G, 4pos:F, 4pos:H, 4pos:I, 4pot:B, 4pot:A, 4pot:C, 4pot:D, 4pot:E, 4pot:G, 4pot:F, 4pot:H, 4pot:I, 4pot:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218