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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GKSTYKIPDFTPYLKKDRNTDANRLFSYFMIGSFGMLSAAGAKATVQDFLSNMSASADVLAMAKVEVKLGAIPLGKNVII
KWRGKPIFIRHRTSEEIEEANEVNVATLRDPQTDDERVQKPEWLVMIGVCTHLGCVPIGEAGDFGGWFCPCHGSHYDISG
RIRRGPAPLNLEIPEYDFADAETLVI

The query sequence (length=186) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ab7:P 186 186 1.0000 1.0000 1.0000 1.18e-140 8ab7:E, 8ab8:P, 8ab9:P, 8aba:P, 8abb:P, 8abe:P, 8abf:P, 8abg:P, 8abh:P, 8abi:P, 8abj:P, 8abk:P, 8abm:P, 8ac3:P, 8ac4:P, 8ac5:P
2 7rja:C 181 182 0.7312 0.7514 0.7473 1.33e-106 7rja:M, 7rjb:E, 7rjc:E, 7rjd:E, 7rje:C, 7rje:M
3 3cx5:P 185 185 0.6667 0.6703 0.6703 6.40e-101 3cx5:E, 3cxh:P, 3cxh:E, 8e7s:C, 8e7s:c, 8ec0:C, 8ec0:c, 1ezv:E, 6giq:E, 6giq:P, 6hu9:E, 6hu9:P, 2ibz:E, 1kb9:E, 1kyo:E, 1kyo:P, 1p84:E, 4pd4:E, 6t0b:E, 6t0b:P, 6t15:E, 6t15:P, 6ymx:E, 6ymx:P
4 8q1b:E 182 180 0.6667 0.6813 0.6889 2.21e-96 8q1b:P
5 2a06:E 196 190 0.5645 0.5357 0.5526 6.03e-79 2a06:R, 1bcc:E, 2bcc:E, 3bcc:E, 1be3:E, 1bgy:Q, 4d6t:R, 4d6u:R, 7dkf:Q1, 2fyu:E, 5gpn:E, 5gpn:Q, 5gup:2, 5gup:4, 6haw:E, 8iog:C, 8iog:c, 5j4z:AE, 5j4z:AP, 5j7y:AE, 5j7y:AP, 5j8k:AE, 5j8k:AP, 5klv:E, 1l0l:E, 1l0n:E, 5luf:q, 6nhg:E, 5nmi:E, 1ntk:E, 1ntm:E, 1ntz:E, 1nu1:E, 7o37:E, 7o37:P, 7o3c:E, 7o3c:P, 7o3h:E, 7o3h:P, 5okd:E, 8p65:E, 8p65:R, 1pp9:R, 1pp9:E, 1ppj:R, 1ppj:E, 8pw5:E, 8pw5:P, 8pw6:E, 8pw6:P, 8pw7:E, 8pw7:P, 6q9e:f1, 6q9e:f2, 6qbx:f1, 6qbx:f2, 6qc2:f1, 6qc2:f2, 6qc3:f1, 6qc3:f2, 6qc4:f1, 6qc4:f2, 7r3v:E, 1rie:A, 1sqb:E, 1sqp:E, 1sqq:E, 1sqv:E, 1sqx:E, 7tay:E, 7tz6:E, 7tz6:R, 8ugd:3E, 8ugd:3R, 8uge:3E, 8uge:3R, 8ugf:3E, 8ugf:3R, 8ugg:3E, 8ugg:3R, 8ugh:3E, 8ugh:3R, 8ugi:3E, 8ugi:3R, 8ugj:3E, 8ugj:3R, 8ugk:3E, 8ugk:3R, 8ugn:3E, 8ugn:3R, 8ugr:3E, 8ugr:3R, 8ugr:6E, 8ugr:6R, 5xte:C, 5xte:P, 5xth:AC, 5xth:AP, 5xti:AC, 5xti:AP, 6xvf:E, 2ybb:e, 2ybb:E, 6zfs:E, 6zft:E, 6zfu:E
6 3cwb:E 196 189 0.5430 0.5153 0.5344 3.47e-78 3cwb:R, 3h1h:E, 3h1h:R, 3h1i:R, 3h1i:E, 3h1j:R, 3h1j:E, 3h1k:E, 3h1k:R, 3h1l:E, 3h1l:R, 3l70:E, 3l70:R, 3l71:E, 3l71:R, 3l72:E, 3l72:R, 3l73:E, 3l73:R, 3l74:E, 3l74:R, 3l75:E, 3l75:R, 3tgu:E, 3tgu:R, 4u3f:E, 4u3f:R
7 8bpx:AD 196 165 0.5054 0.4796 0.5697 3.08e-71 8bel:D, 8bel:N, 8bpx:BD, 8bq5:AD, 8bq5:BD, 8bq6:AD, 8bq6:BD
8 8iuf:QE 231 147 0.4194 0.3377 0.5306 2.11e-55 8iuf:Qe, 8iuj:QE, 8iuj:Qe
9 2yiu:F 174 150 0.4355 0.4655 0.5400 1.14e-53 2yiu:C
10 1zrt:E 183 182 0.4624 0.4699 0.4725 2.65e-52 6xi0:E, 6xi0:R, 6xkt:E, 6xkt:R, 6xku:E, 6xku:R, 6xkv:E, 6xkv:R, 6xkw:E, 6xkw:R, 6xkx:E, 6xkx:R, 6xkz:E, 6xkz:R, 1zrt:R
11 8asi:E 181 151 0.4032 0.4144 0.4967 4.36e-44 8asi:A, 8asj:A, 8asj:E, 2fyn:C, 2fyn:F, 2fyn:I, 2fyn:L, 2fyn:O, 2fyn:R, 5kkz:G, 5kkz:C, 5kkz:Q, 5kkz:M, 5kli:C, 5kli:G, 5kli:M, 5kli:Q, 6nhh:C, 6nhh:G, 6nin:C, 6nin:G, 6nin:M, 6nin:Q, 6nin:U, 6nin:Y, 2nuk:A, 2num:A, 2nve:A, 2nvf:A, 2nvg:A, 2nwf:A, 2qjk:C, 2qjk:F, 2qjk:I, 2qjk:L, 2qjk:O, 2qjk:R, 2qjp:F, 2qjp:C, 2qjp:L, 2qjp:I, 2qjy:F, 2qjy:C, 2qjy:L, 2qjy:I, 2qjy:R, 2qjy:O, 7tce:C, 7tce:G, 7tce:M, 7tce:Q, 7tlj:G, 7tlj:C
12 8ibd:AE 109 164 0.3495 0.5963 0.3963 5.41e-34 8ibg:AE
13 8smr:Z 194 188 0.3925 0.3763 0.3883 1.16e-31 8smr:C, 8snh:C, 8snh:Z
14 8b6j:E 245 122 0.2849 0.2163 0.4344 9.60e-26 8b6j:e, 8bqs:E, 8bqs:e, 8gym:qE, 8gym:qe, 8gym:QE, 8gym:Qe, 8gzu:qE, 8gzu:qe, 8gzu:QE, 8gzu:Qe, 7tgh:3E
15 7yr9:A 146 142 0.2849 0.3630 0.3732 8.87e-24 7yr9:B, 7yra:A, 7yra:B
16 6rqf:L 179 59 0.1452 0.1508 0.4576 3.39e-11 7qrm:D, 7qrm:L, 1rfs:A, 6rqf:D, 7zyv:D, 7zyv:L
17 3azc:A 133 58 0.1398 0.1955 0.4483 1.42e-10
18 1q90:C 126 52 0.1398 0.2063 0.5000 2.05e-10
19 2d2c:D 168 45 0.1398 0.1548 0.5778 2.51e-10 2d2c:Q, 2e74:D, 2e75:D, 2e76:D, 4h0l:D, 4h13:D, 4i7z:D, 4pv1:D, 1vf5:D, 1vf5:Q
20 7r0w:D 169 45 0.1290 0.1420 0.5333 6.20e-10 7r0w:L, 7zxy:D, 7zxy:L
21 4h44:D 166 88 0.1828 0.2048 0.3864 8.80e-10 4ogq:D, 2zt9:D
22 8hn2:A 110 58 0.1344 0.2273 0.4310 2.85e-07 8hn2:B
23 6kls:A 134 114 0.1667 0.2313 0.2719 5.24e-06 6kls:D, 6klv:A, 6klv:D
24 5cxm:A 99 48 0.0968 0.1818 0.3750 5.76e-04 5cxm:B, 5cxm:C, 5cxm:D
25 3fou:A 156 30 0.0806 0.0962 0.5000 0.001 3fou:B, 1nyk:A, 1nyk:B
26 1jm1:A 202 68 0.1398 0.1287 0.3824 0.016
27 4y1p:B 336 71 0.1022 0.0565 0.2676 0.084 4y1p:A
28 3asj:A 333 34 0.0806 0.0450 0.4412 0.092 3asj:B, 3asj:C, 3asj:D, 4yb4:A, 4yb4:B, 4yb4:C, 4yb4:D
29 8e73:E 74 42 0.0860 0.2162 0.3810 0.11 8e73:Q
30 7e1v:A 378 76 0.1183 0.0582 0.2895 0.23 7e1v:M, 7e1w:M, 7e1w:A, 7e1x:M, 7e1x:A, 8hcr:A, 8hcr:M
31 7qhm:A 402 41 0.0806 0.0373 0.3659 0.39 7q21:A, 7q21:a, 7qhm:N, 7qho:A, 7qho:N
32 5hn4:A 329 29 0.0753 0.0426 0.4828 0.81 5hn6:A
33 6adq:A 382 29 0.0645 0.0314 0.4138 1.2 6adq:M, 6hwh:A, 6hwh:B, 8ovc:M, 8ovc:G, 8ovd:M, 8ovd:G, 7rh5:M, 7rh5:Y, 7rh6:M, 7rh6:Y, 7rh7:Y, 7rh7:M
34 6hit:A 142 45 0.0699 0.0915 0.2889 2.0 6hit:C, 6hit:E, 6hit:G
35 5j32:A 369 39 0.0753 0.0379 0.3590 2.2 5j32:B, 5j32:C, 5j32:D, 5j33:A, 5j33:B, 5j33:C, 5j33:H, 5j33:D, 5j33:F, 5j33:E, 5j33:G, 5j34:A, 5j34:B, 5j34:C, 5j34:D
36 5xbp:A 444 43 0.0753 0.0315 0.3256 3.2 5xbp:D, 5xbp:G
37 3ty3:A 358 29 0.0753 0.0391 0.4828 4.7 3ty3:B
38 2bmo:A 437 43 0.0753 0.0320 0.3256 5.7 2bmq:A, 2bmr:A
39 7c79:K 104 32 0.0645 0.1154 0.3750 6.6 7c7a:K
40 5aeu:A 433 43 0.0753 0.0323 0.3256 9.4 5aeu:C, 5aeu:E, 5aeu:G, 5aew:A, 5aew:C, 5aew:E, 5aew:G, 5aew:I, 5aew:K, 5aew:M, 5aew:O, 5aew:Q, 5aew:S, 5aew:U, 5aew:W, 2xr8:A, 2xr8:C, 2xr8:E, 2xr8:G, 2xr8:I, 2xr8:K, 2xr8:M, 2xr8:O, 2xr8:Q, 2xr8:S, 2xr8:U, 2xr8:W, 2xrx:A, 2xrx:C, 2xrx:E, 2xrx:G, 2xrx:I, 2xrx:K, 2xrx:M, 2xrx:O, 2xrx:Q, 2xrx:S, 2xrx:U, 2xrx:W, 2xsh:A, 2xsh:C, 2xsh:E, 2xsh:G, 2xsh:I, 2xsh:K, 2xso:A, 2xso:C, 2xso:E, 2xso:G, 2xso:I, 2xso:K, 2xso:M, 2xso:O, 2xso:Q, 2xso:S, 2xso:U, 2xso:W, 2yfi:A, 2yfi:C, 2yfi:E, 2yfi:G, 2yfi:I, 2yfi:K, 2yfj:A, 2yfj:C, 2yfj:E, 2yfj:G, 2yfj:I, 2yfj:K, 2yfl:A, 2yfl:C, 2yfl:E, 2yfl:G, 2yfl:I, 2yfl:K
41 2fuv:A 545 38 0.0699 0.0239 0.3421 9.4 2fuv:B, 3na5:A, 3na5:B, 3olp:A, 3olp:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218