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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GKSENTIRFLTFNVNGIRTFFHYQPFSQMNQSLRSVFDFFRADIITFQQLKTEKLSISKWGRVDGFYSFISIPQTRKGYS
GVGCWIRIPEKNHPLYHALQVVKAEEGITGYLTIKNGKHSAISYRNDVNQGIGGYDSLDPDLDEKSALELDSEGRCVMVE
LACGIVIISVYCPANSNSSEEGEMFRLRFLKVLLRRVRNLDKIGKKIVLMGNVNVCRDLIDSADTLEQFSIPITDPMGGT
KLEAQYRDKAIQFIINPDTPHRRIFNQILADSLLPDASKRGILIDTTRLIQTRNRLKMYTVWNMLKNLRPSNYGSRIDFI
LVSLKLERCIKAADILPDILGSDHCPVYSDLDILDQVPIPKFEARYKYNLR

The query sequence (length=371) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7n3z:A 379 378 0.9919 0.9710 0.9735 0.0 7n3y:B, 7n3y:C, 7n3y:A, 7n3y:D
2 6wcd:A 314 351 0.2426 0.2866 0.2564 2.83e-27
3 8ka5:A 297 345 0.2345 0.2929 0.2522 2.04e-15 8ka3:A, 8ka4:B, 8ka4:C
4 3fzi:A 258 351 0.2075 0.2984 0.2194 2.93e-15 3g00:A, 3g00:B, 3g0a:A, 3g0r:A, 3g0r:B, 3g1k:A, 3g1k:B, 3g2c:A, 3g2c:B, 3g2d:A, 3g2d:B, 3g38:A, 3g3c:A, 3g3c:B, 3g3y:B, 3g3y:A, 3g4t:A, 3g4t:B, 3ga6:A, 3ga6:B, 3w2x:A, 3w2y:A, 3w2y:D
5 5j8n:A 258 346 0.2183 0.3140 0.2341 2.99e-15
6 8igi:A 251 341 0.2237 0.3307 0.2434 1.26e-13 8igi:B
7 5cfe:A 252 199 0.1482 0.2183 0.2764 1.00e-11
8 6mkk:A 282 352 0.2318 0.3050 0.2443 1.09e-10 6boq:A, 6bor:A, 6bos:A, 6bot:A, 6bou:A, 6bov:A, 6bow:A, 7cd5:A, 7cd6:A, 5cfg:A, 1de8:B, 1de8:A, 1de9:A, 1de9:B, 1dew:B, 1dew:A, 5dff:A, 5dfh:A, 5dfi:A, 5dfj:A, 5dg0:A, 4iem:A, 4iem:B, 4iem:C, 4iem:D, 2isi:A, 2isi:B, 2isi:C, 4lnd:A, 4lnd:B, 4lnd:C, 7lpg:D, 7lph:D, 7lpi:D, 7lpj:D, 7mcr:A, 7mev:A, 6p93:A, 6p94:A, 4qh9:A, 4qhe:A, 7suv:B, 7svb:B, 7tc2:A, 7tc2:B, 7tc2:C, 7tc2:D, 7tr7:A, 7u50:K, 3u8u:A, 3u8u:B, 3u8u:C, 3u8u:D, 3u8u:E, 3u8u:F, 6w0q:A, 6w2p:A, 6w3l:B, 6w3n:B, 6w3q:B, 6w3u:B, 6w43:A, 6w4i:A, 6w4i:B, 6w4t:A, 6w4t:B, 5wn0:A, 5wn1:A, 5wn2:A, 5wn3:B, 5wn4:B, 5wn5:B, 5wn5:A
9 4b5g:A 259 347 0.2022 0.2896 0.2161 7.55e-06 4b5f:A, 4b5g:B, 4b5g:C, 4b5h:A, 4b5i:A, 4b5j:A, 4b5m:A, 4b5m:B, 4b5m:C, 2jc5:A
10 5trq:A 283 70 0.0539 0.0707 0.2857 0.21 8acv:A, 8acv:B, 8aut:A, 8aut:B, 8aut:C, 8aut:D, 6gem:A, 6gem:B, 6gem:C, 6gem:D, 5iqs:A, 5iqs:B, 5iqs:C, 5iqt:A, 5iqt:B, 5iqt:C, 5iqu:A, 5iqv:A, 5iqv:B, 5iqv:C, 5j4r:A, 5t22:A, 5t22:B
11 8i9z:CE 465 65 0.0539 0.0430 0.3077 1.5 8i9p:CE, 8i9r:CE, 8i9t:CE, 8i9v:CE, 8i9w:CE, 8i9x:CE, 8i9y:CE, 8ia0:CE
12 4bqk:A 424 45 0.0431 0.0377 0.3556 1.5 4b8o:A, 4b8p:A, 4b8p:B, 4bpl:A, 4bqk:B, 2yns:A, 2yns:B
13 4n2i:A 662 56 0.0539 0.0302 0.3571 1.9 4n22:A, 4n24:A, 4n26:A, 4n28:A, 4n2a:A, 4n2b:A, 4n2c:A, 4n2e:A, 4n2g:A, 4n2l:A, 4n2m:A, 4n2n:A
14 4n20:A 639 56 0.0539 0.0313 0.3571 1.9 4n25:A, 4n2d:A, 4n2f:A, 4n2h:A, 4n2k:A
15 4pj3:A 1335 47 0.0458 0.0127 0.3617 6.2 7a5p:U, 6icz:Q, 6id1:Q, 7w59:Q, 7w5a:Q, 7w5b:Q, 5xjc:Q
16 8tdi:G 386 140 0.0836 0.0803 0.2214 7.0 8tdi:L, 8tdi:J, 8tdi:A, 8tdi:C, 8tdi:D, 8tdi:E, 8tdi:F, 8tdi:H, 8tdi:I, 8tdi:B, 8tdi:K
17 5ftw:A 255 58 0.0539 0.0784 0.3448 9.5
18 5la4:A 508 37 0.0350 0.0256 0.3514 9.8 8b0b:AAA, 8b0b:BBB, 8b0c:AAA, 8b0c:BBB, 8bac:AAA, 8bac:BBB, 8cqi:A, 8cqi:B, 8e07:A, 8e07:B, 8e08:A, 8e08:B, 5e8m:A, 5e97:A, 5e97:B, 5e98:A, 5e98:B, 5e9b:A, 5e9b:B, 5e9c:A, 5e9c:B, 8jyg:A, 8jyg:B, 5l9y:A, 5l9y:B, 5l9z:A, 5l9z:B, 5la7:A, 8ohq:AAA, 8ohq:BBB, 8ohr:AAA, 8ohr:BBB, 7pr7:A, 7pr7:B, 7pr8:A, 7pr8:B, 7prt:A, 7prt:B, 7yi7:A, 7yi7:B, 7yjc:A, 7yjc:B, 6zdm:AAA, 6zdm:BBB

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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