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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGY
NCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSD
VSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVK
IGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATIS
PASLNLEETLSTLEYAHRAKNILNKPE

The query sequence (length=347) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4aqv:C 361 349 0.9856 0.9474 0.9799 0.0 4a28:A, 4a50:A, 4a5y:A, 4a5y:C, 4as7:A, 4b7b:A, 4bbg:A, 4bxn:A, 4bxn:B, 3cjo:A, 3cjo:B, 4ck6:C, 4ck7:C, 2fky:A, 2fky:B, 2fl2:A, 2fl2:B, 2fl6:A, 2fl6:B, 2fme:B, 2g1q:A, 2g1q:B, 6g6z:A, 6hkx:B, 3hqd:A, 3hqd:B, 2ieh:A, 2ieh:B, 1ii6:A, 1ii6:B, 3k3b:A, 3k3b:B, 3k5e:A, 3ken:A, 3l9h:A, 3l9h:B, 2pg2:A, 2pg2:B, 1q0b:A, 1q0b:B, 2q2y:A, 2q2y:B, 2q2z:A, 2q2z:B, 6ta4:K, 6tle:A, 6tle:B, 6trl:B, 2uyi:A, 2uyi:B, 2uym:A, 2uym:B, 2wog:A, 2wog:B, 2wog:C, 2x2r:A, 2x2r:C, 2x7c:A, 2x7c:B, 2x7d:A, 2x7d:B, 2x7e:A, 2x7e:B, 1x88:A, 1x88:B, 2xae:C, 1yrs:A, 1yrs:B, 4zca:A, 4zhi:A, 4zhi:B, 5zo7:A, 5zo7:B
2 5zo8:A 331 346 0.9424 0.9879 0.9451 0.0 4a51:G, 4a51:E, 4a51:F, 4a5y:B, 4ap0:D, 4ap0:B, 2gm1:B, 2gm1:D, 6hky:C, 6trl:A, 8yhh:B, 5zo8:B, 5zo9:A, 5zo9:B
3 6ta3:K 334 349 0.9395 0.9760 0.9341 0.0 4a1z:A, 4a1z:B, 4a28:B, 4a51:A, 4a51:B, 4a51:C, 4a51:D, 4ap0:A, 2fme:A, 6g6y:A, 2gm1:A, 2gm1:E, 6hkx:A, 6hky:A, 6hky:B, 3k5e:B, 6tiw:K, 2x2r:B, 2xae:A, 2xae:B, 6y1i:A, 6y1i:B, 6y1i:C, 8yhh:A, 3zcw:A, 4zca:B
4 4ap0:C 311 344 0.8847 0.9871 0.8924 0.0
5 3wpn:A 309 347 0.8703 0.9773 0.8703 0.0
6 7lxr:B 344 346 0.5937 0.5988 0.5954 1.17e-140 7lxr:A, 6vpo:C, 2wbe:C
7 5mm7:K 397 380 0.5620 0.4912 0.5132 2.30e-116 5mm4:K
8 6s8m:K 344 349 0.5043 0.5087 0.5014 5.50e-110
9 5m5i:C 369 365 0.5274 0.4959 0.5014 6.91e-110 5m5l:C, 5m5m:C, 5m5n:C, 5m5o:C
10 7nba:K 331 351 0.4524 0.4743 0.4473 1.12e-95
11 3b6u:B 343 349 0.4524 0.4577 0.4499 8.75e-95 3b6u:A
12 7a5e:A 338 349 0.4496 0.4615 0.4470 1.21e-87 7a5e:B
13 1goj:A 354 349 0.4438 0.4350 0.4413 1.30e-84
14 3zfd:A 340 349 0.4409 0.4500 0.4384 2.00e-84 3zfc:A
15 3b6v:A 306 346 0.4150 0.4706 0.4162 7.16e-79 3b6v:B
16 2vvg:B 309 346 0.4121 0.4628 0.4133 1.86e-74 2vvg:A
17 6zpi:C 332 306 0.4063 0.4247 0.4608 7.17e-74 4bn2:A, 4bn2:B, 6zph:B
18 5hnw:K 329 339 0.4352 0.4590 0.4454 1.52e-72 5hle:A, 5hny:K, 3x2t:B
19 7a3z:A 307 348 0.4150 0.4691 0.4138 4.66e-72
20 7rx0:C 328 342 0.4035 0.4268 0.4094 8.27e-72 6mlq:C, 6mlr:C
21 4uy0:C 333 349 0.4352 0.4535 0.4327 9.48e-72
22 5ocu:K 333 345 0.3890 0.4054 0.3913 2.80e-70 5ogc:K
23 8uto:N 389 369 0.3977 0.3548 0.3740 3.63e-70 2hxh:C, 1i5s:A, 8utn:K, 8utn:N, 8uto:K, 8utp:K, 8utp:N, 8utq:K, 8utr:K, 8utt:K, 8utt:N, 8utu:K, 8utv:K, 8uty:K, 8uty:N, 4uxp:C, 1vfz:A
24 1mkj:A 336 345 0.4265 0.4405 0.4290 1.02e-68 4atx:C, 1bg2:A, 4hna:K, 8ixa:Y, 8ixa:S, 8ixa:T, 8ixa:U, 8ixa:V, 8ixa:W, 8ixa:X, 8ixa:Z, 8ixa:a, 8ixb:l, 8ixb:g, 8ixb:k, 8ixb:m, 8ixd:Y, 8ixd:S, 8ixd:T, 8ixd:U, 8ixd:V, 8ixd:W, 8ixd:X, 8ixd:Z, 8ixd:a, 8ixe:l, 8ixe:h, 8ixe:p, 8ixe:q, 8ixf:Y, 8ixf:S, 8ixf:T, 8ixf:U, 8ixf:V, 8ixf:W, 8ixf:X, 8ixf:Z, 8ixf:a, 8ixg:l, 8ixg:h, 8ixg:p, 8ixg:q, 3j8y:K, 2p4n:K
25 7z2b:K 308 345 0.3862 0.4351 0.3884 2.27e-68
26 2y65:C 343 345 0.4092 0.4140 0.4116 3.18e-67 2y5w:A, 2y5w:B, 2y65:D, 2y65:B, 2y65:A
27 6wwk:K 368 368 0.4092 0.3859 0.3859 5.00e-67 7lvq:K, 7lvr:K, 6wwf:K, 6wwg:K, 6wwg:N, 6wwh:K, 6wwh:N, 6wwj:K, 6wwk:N, 6wwl:K, 6wwl:N, 6wwm:K, 6wwn:K, 6wwo:K, 6wwq:K, 6wwr:K, 6wws:K, 6wwu:K, 6wwv:K
28 7x4n:E 332 348 0.3977 0.4157 0.3966 8.19e-67
29 7eo9:A 351 357 0.3833 0.3789 0.3725 1.64e-65 7eob:A, 2hxf:C, 1i6i:A, 1ia0:K, 1vfv:A, 1vfw:A, 1vfx:A, 2zfi:A, 2zfj:A, 2zfk:A, 2zfl:A, 2zfm:A
30 4bn2:C 311 351 0.4265 0.4759 0.4217 2.84e-64
31 7tr1:K 346 356 0.4063 0.4075 0.3961 3.32e-64 7lff:A, 7lff:B
32 3lre:B 300 342 0.3746 0.4333 0.3801 4.53e-64 3lre:A, 7rsi:C
33 3x2t:A 311 346 0.4207 0.4695 0.4220 6.37e-64 2kin:A, 3kin:A, 3kin:C
34 3cob:A 355 348 0.3689 0.3606 0.3678 4.85e-63 3cob:C, 1sdm:A
35 7rs5:K 346 360 0.3775 0.3786 0.3639 7.29e-63 7rs5:a, 7rs5:b, 7rs5:c, 7rs5:d, 7rs5:e, 7rs5:f, 7rs5:g, 7rs5:h, 7rs6:K, 7rs6:a, 7rs6:b, 7rs6:c, 7rs6:d, 7rs6:e, 7rs6:f, 7rs6:g, 7rs6:h
36 1t5c:A 322 346 0.3890 0.4193 0.3902 5.12e-62 8hfh:A, 6m4i:A, 6m4i:B, 1t5c:B
37 6a20:A 395 352 0.3833 0.3367 0.3778 1.33e-61 6a1z:A, 7d8v:A, 3gbj:B, 5zbr:B, 5zbr:A, 5zbr:C, 5zbs:B, 5zbs:A
38 7n61:0X 420 348 0.3602 0.2976 0.3592 4.29e-61 7n61:0Y, 7n61:0Z, 7n61:1A
39 5wde:A 320 342 0.3775 0.4094 0.3830 5.41e-61
40 7tr3:K 418 302 0.3602 0.2990 0.4139 7.90e-61 7tqx:K, 7tqy:K, 7tr0:K
41 2xt3:A 300 341 0.3689 0.4267 0.3754 9.17e-59 4a14:A
42 7wrg:A 812 364 0.3775 0.1613 0.3599 7.50e-58
43 4ozq:B 687 351 0.3833 0.1936 0.3789 7.98e-56 4ozq:A
44 2owm:A 328 356 0.3948 0.4177 0.3848 1.15e-55 2owm:B, 2owm:C, 2owm:D
45 5gsz:A 306 348 0.3602 0.4085 0.3592 1.31e-55
46 7wrg:B 783 361 0.3775 0.1673 0.3629 2.23e-55
47 3h4s:A 359 349 0.3545 0.3426 0.3524 4.26e-55 4frz:A, 4frz:B
48 5zbs:C 323 358 0.3689 0.3963 0.3575 1.25e-52 3gbj:A, 3gbj:C
49 5mio:C 477 352 0.3631 0.2642 0.3580 1.86e-51 1v8j:A, 5xjb:A
50 5nd4:C 337 361 0.3343 0.3442 0.3213 3.69e-51
51 1cz7:D 365 340 0.3256 0.3096 0.3324 2.07e-49 1cz7:A, 1cz7:B, 1cz7:C, 3l1c:A, 1n6m:A, 2ncd:A, 3u06:A, 5w3d:A
52 3cnz:A 333 348 0.3458 0.3604 0.3448 3.05e-49 3cnz:B
53 6nje:A 297 301 0.3314 0.3872 0.3821 2.60e-48
54 4etp:A 379 346 0.3516 0.3219 0.3526 4.47e-48 1f9t:A, 1f9u:A, 1f9v:A, 3kar:A
55 6b0l:K 368 303 0.3112 0.2935 0.3564 3.35e-47 6b0c:K
56 6bbn:E 378 345 0.3372 0.3095 0.3391 9.67e-47 2gry:A
57 5nd7:C 300 342 0.3170 0.3667 0.3216 1.75e-46
58 3nwn:A 308 348 0.3285 0.3701 0.3276 9.19e-46
59 3dcb:A 299 296 0.2939 0.3411 0.3446 1.18e-45 3dc4:A, 3dco:N, 3pxn:A
60 4gkr:B 307 343 0.3372 0.3811 0.3411 8.94e-44 4gkr:A
61 3t0q:A 304 353 0.3573 0.4079 0.3513 1.77e-41
62 3u06:B 344 337 0.2997 0.3023 0.3086 1.91e-41 3l1c:B, 1n6m:B
63 5wdh:A 296 340 0.3314 0.3885 0.3382 2.31e-41
64 4h1g:A 670 350 0.3343 0.1731 0.3314 1.46e-40
65 5nd2:C 280 338 0.3055 0.3786 0.3136 1.76e-40
66 5xja:A 337 350 0.3458 0.3561 0.3429 3.14e-40 3edl:D, 2heh:A, 4ubf:B, 4ubf:C, 4ubf:D, 1v8k:A, 5xja:B, 5xjb:B, 4y05:A
67 4ubf:A 309 343 0.3314 0.3722 0.3353 2.52e-38
68 1f9w:A 300 343 0.3256 0.3767 0.3294 2.47e-35 1f9w:B
69 5w3d:B 313 336 0.2911 0.3227 0.3006 6.86e-32
70 8bjs:A 343 395 0.2997 0.3032 0.2633 9.63e-32
71 8ad2:A 165 42 0.0432 0.0909 0.3571 3.9 8ad2:B, 8ad2:C, 8ad2:D, 8ad2:F, 8ad2:G, 8qmg:A, 8qmg:B, 8qmg:C, 8qmg:D, 8qmg:F, 8qmg:G
72 6g7o:A 350 52 0.0490 0.0486 0.3269 5.0 6yxh:A
73 1eye:A 256 60 0.0519 0.0703 0.3000 5.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218