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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GKIKIGINGFGRIGRLVARVALQSEDVELVAVNDPFITTDYMTYMFKYDTVHGQWKHSDIKIKDSKTLLLGEKPVTVFGI
RNPDEIPWAEAGAEYVVESTGVFTDKEKAAAHLKGGAKKVVISAPSKDAPMFVCGVNEDKYTSDIDIVSNASCTTNCLAP
LAKVIHDNFGIIEGLMTTVHAITATQKTVDGPSSKDWRGGRAASFNIIPSSTGAAKAVGKVLPDLNGKLTGMSFRVPTVD
VSVVDLTVRIEKAASYDAIKSAIKSASEGKLKGIIGYVEEDLVSTDFVGDSRSSIFDAKAGIALNDNFVKLVAWYDNEWG
YSNRVIDLIRHMAKTQ

The query sequence (length=336) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3e5r:O 336 336 1.0000 1.0000 1.0000 0.0 3e5r:A, 3e5r:B, 3e5r:C, 3v1y:O, 3v1y:A, 3v1y:B, 3v1y:C
2 6qun:O 334 333 0.8601 0.8653 0.8679 0.0 6qun:R, 6quq:O, 6quq:R, 4z0h:O, 4z0h:R
3 1dss:G 333 331 0.6935 0.6997 0.7039 8.26e-175 1dss:R, 1gpd:G, 1gpd:R, 1ihx:A, 1ihx:B, 1ihx:C, 1ihx:D, 1ihy:A, 1ihy:B, 1ihy:C, 1ihy:D, 1szj:G, 1szj:R
4 6m61:O 336 336 0.6845 0.6845 0.6845 2.14e-174 6ade:A, 5ddi:P, 5ddi:R, 5ddi:S, 6iq6:A, 6iq6:B, 6iq6:C, 6iq6:D, 6iq6:E, 1j0x:P, 1j0x:R, 6lgj:A, 6lgj:B, 6lgj:C, 6lgj:D, 6lgk:A, 6lgk:B, 6lgk:C, 6lgm:A, 6lgm:B, 6lgm:C, 6m61:Q, 6m61:P, 4o59:O, 4o59:P, 4o59:R, 4o59:Q, 4o63:P, 4o63:Q, 4o63:R, 8p5f:AAA, 8p5f:DDD, 8p5f:EEE, 8p5f:GGG, 5tso:P, 5tso:R, 5tso:S, 7u5m:A, 7u5m:B, 7u5m:C, 7u5m:D, 1u8f:P, 1u8f:Q, 1u8f:R, 4wnc:O, 4wnc:E, 4wnc:A, 4wnc:B, 4wnc:C, 4wnc:D, 4wni:O, 4wni:A, 4wni:B, 1znq:O, 1znq:P, 1znq:R, 1znq:Q
5 8de5:A 338 332 0.6935 0.6893 0.7018 1.41e-173
6 7xzg:A 334 332 0.6875 0.6916 0.6958 5.62e-170 7xzg:B, 7xzg:C, 7xzg:D
7 3gpd:R 334 336 0.6696 0.6737 0.6696 1.83e-168 3gpd:G
8 4k9d:A 338 336 0.6786 0.6746 0.6786 1.25e-163 4k9d:B, 4k9d:C, 4k9d:D, 4k9d:E, 4k9d:F, 4k9d:G, 4k9d:H
9 3pym:A 332 332 0.6429 0.6506 0.6506 1.66e-162 3pym:B
10 6m5x:O 334 331 0.6518 0.6557 0.6616 3.44e-160 6m5x:R, 6m5x:P, 6m5x:Q
11 2vyn:D 334 331 0.6399 0.6437 0.6495 7.32e-160 2vyv:D
12 4mvj:B 332 333 0.6548 0.6627 0.6607 3.70e-158 1dc4:A, 1dc4:B, 1dc6:A, 1dc6:B, 1gad:O, 1gad:P, 1gae:O, 1gae:P, 6io6:A, 4mvj:A, 4mvj:C, 4mvj:D, 4mvj:E, 4mvj:F, 4mvj:G, 4mvj:I, 4mvj:J, 4mvj:K, 4mvj:L, 4mvj:M, 4mvj:O, 4mvj:P, 6utm:A, 6utm:B, 6utn:A, 6utn:B, 6uto:A, 6uto:B, 2vyn:A, 2vyn:B, 2vyn:C, 2vyv:A, 2vyv:B, 2vyv:C, 5za0:A
13 6px2:A 332 332 0.6488 0.6566 0.6566 7.92e-157 6px2:B, 6px2:C, 6px2:D, 6px2:E, 6px2:F, 6px2:G, 6px2:H
14 3h9e:P 337 332 0.6190 0.6172 0.6265 7.98e-156 5c7o:O, 5c7o:P, 3h9e:O, 3pfw:O, 3pfw:P
15 6nlx:C 335 335 0.6220 0.6239 0.6239 6.96e-154 6nlx:B, 6nlx:D, 5ur0:A, 5ur0:B, 5ur0:C, 5ur0:D
16 1ywg:O 337 336 0.6250 0.6231 0.6250 5.52e-151 2b4r:O, 2b4r:P, 2b4r:Q, 2b4r:R, 2b4t:O, 2b4t:P, 2b4t:Q, 2b4t:R, 1ywg:P, 1ywg:Q, 1ywg:R
17 4p8r:A 331 333 0.6131 0.6224 0.6186 3.87e-147 4p8r:B, 4p8r:C, 4p8r:D
18 3sth:C 340 334 0.6250 0.6176 0.6287 1.97e-146 3sth:A, 3sth:B, 3sth:D
19 4lsm:A 331 332 0.5982 0.6073 0.6054 6.05e-145 4lsm:B
20 3cif:A 338 334 0.6071 0.6036 0.6108 3.53e-144 3cif:B, 3cif:C, 3cif:D, 3cps:A, 3cps:B, 8pvf:A, 1vsv:A, 1vsv:B, 1vsv:C, 1vsv:D
21 2i5p:O 309 331 0.5893 0.6408 0.5982 8.40e-141 2i5p:P
22 8oha:B 336 338 0.5923 0.5923 0.5888 2.46e-137 8oha:A, 8oha:C, 8oha:D, 8oha:E, 8oha:F, 8oha:G, 8oha:H
23 6ok4:A 334 334 0.5565 0.5599 0.5599 1.98e-130 6ok4:B, 6ok4:C, 6ok4:D, 6wyc:A, 6wyc:B, 6wyc:C, 6wyc:D, 6x2e:A, 6x2e:C, 6x2e:D
24 3dmt:A 359 349 0.5685 0.5320 0.5473 1.26e-126 3dmt:B, 3dmt:C, 3dmt:D, 3ids:D, 1k3t:C, 1ml3:B, 1ml3:C, 1ml3:D, 1qxs:C, 1qxs:D, 1qxs:A, 1qxs:B, 2x0n:A, 2x0n:B, 2x0n:O, 2x0n:P, 2x0n:Q, 2x0n:R
25 1a7k:A 358 349 0.5655 0.5307 0.5444 2.22e-125 1a7k:B, 1a7k:C, 1a7k:D, 1gyp:A, 1gyp:B, 1gyp:C, 1gyp:D, 1gyq:A, 1gyq:B, 1gyq:C, 1gyq:D, 1i32:A, 1i32:B, 1i32:C, 1i32:D, 1i32:E, 1i32:F, 1i33:A, 1i33:B, 1i33:C, 1i33:D, 1i33:E, 1i33:F
26 3cmc:O 334 333 0.5030 0.5060 0.5075 3.58e-114 3cmc:P, 3cmc:Q, 3cmc:R, 1dbv:O, 1dbv:P, 1dbv:Q, 1dbv:R, 2dbv:O, 2dbv:P, 2dbv:Q, 2dbv:R, 3dbv:O, 3dbv:P, 3dbv:Q, 3dbv:R, 4dbv:O, 4dbv:P, 4dbv:Q, 4dbv:R, 1gd1:O, 1gd1:P, 1gd1:Q, 1gd1:R, 1npt:O, 1npt:P, 1npt:Q, 1npt:R, 1nq5:O, 1nq5:Q, 1nq5:A, 1nq5:C, 1nqa:O, 1nqa:P, 1nqa:Q, 1nqa:R, 1nqo:O, 1nqo:Q, 1nqo:A, 1nqo:C
27 8br4:A 339 340 0.4940 0.4897 0.4882 4.81e-108 8br4:B, 8br4:C, 8br4:D, 8br4:E, 8br4:F, 8br4:G, 8br4:H, 8br4:I, 8br4:J, 8br4:K, 8br4:L, 8br4:M, 8br4:N, 8br4:O, 8br4:P
28 6ghr:B 342 337 0.4970 0.4883 0.4955 4.51e-106 4boy:A, 4boy:B, 6gfo:A, 6gfo:B, 6gfo:C, 6gfo:D, 6gfp:A, 6gfp:B, 6gfq:B, 6gfq:A, 6gfr:A, 6gfr:B, 6gg7:B, 6gg7:A, 6ghl:A, 6ghl:D, 6ghl:B, 6ghl:C, 6ghr:D, 6ghr:A, 6ghr:C, 6gve:D, 6gve:A, 6gve:E, 6gve:F, 6gve:I, 6gve:K, 6gve:N, 6gve:O, 3zcx:A, 3zcx:B, 3zdf:B, 3zdf:A
29 1hdg:O 332 334 0.4643 0.4699 0.4671 1.30e-105 1hdg:Q
30 2ep7:B 339 342 0.4881 0.4838 0.4795 3.59e-104 2ep7:A
31 3doc:A 335 330 0.4554 0.4567 0.4636 1.58e-102 3doc:B, 3doc:C, 3doc:D
32 7bew:A 330 336 0.4762 0.4848 0.4762 8.55e-102 7bex:A
33 3hja:A 334 338 0.4702 0.4731 0.4675 3.23e-96 3hja:B, 3hja:C, 3hja:D
34 1cer:O 331 329 0.4762 0.4834 0.4863 1.35e-95 1cer:P, 1cer:Q, 1cer:R, 1cer:A, 1cer:B, 1cer:C, 1cer:D, 2g82:O, 2g82:P, 2g82:Q, 2g82:R, 2g82:A, 2g82:B, 2g82:C, 2g82:D, 1vc2:A
35 3l0d:A 332 336 0.4315 0.4367 0.4315 5.52e-95 3l0d:B
36 5vmt:B 334 336 0.4435 0.4461 0.4435 6.71e-94 5vmt:A, 5vmt:C, 5vmt:D, 5vmt:F, 5vmt:G, 5vmt:H
37 3gnq:C 335 330 0.4613 0.4627 0.4697 1.97e-93 3gnq:B, 3gnq:D, 3gnq:E, 3gnq:F, 3gnq:G, 3gnq:H
38 7q54:C 368 333 0.4762 0.4348 0.4805 2.70e-93 2pkq:O, 2pkq:Q, 2pkq:T, 7q53:O, 7q53:Q, 7q54:Q, 7q54:O, 7q54:A, 7q55:O, 7q55:Q, 7q55:A, 7q55:C, 7q55:E, 7q55:G, 7q55:I, 7q55:K, 7q56:K, 7q56:E, 7q56:I, 7q56:A, 7q56:G, 7q56:C, 7q56:Q, 7q56:O, 7q57:O, 7q57:Q, 7q57:A, 7q57:C, 7q57:G, 7q57:E, 7q57:I, 7q57:K, 7q57:M, 7q57:S
39 1nbo:O 337 330 0.4554 0.4540 0.4636 2.66e-92 1jn0:O, 1jn0:A, 1jn0:B, 1nbo:A, 1nbo:B, 2pkq:P, 2pkq:R, 2pkq:S, 2pkr:O, 2pkr:R, 2pkr:P, 2pkr:Q, 2pkr:A, 2pkr:B, 2pkr:C, 2pkr:D, 2pkr:H, 2pkr:I, 2pkr:L, 2pkr:M, 7q53:P, 7q53:R, 7q54:R, 7q54:P, 7q54:B, 7q54:D, 7q55:P, 7q55:R, 7q55:B, 7q55:D, 7q55:F, 7q55:H, 7q55:J, 7q55:L, 7q56:J, 7q56:L, 7q56:B, 7q56:D, 7q56:R, 7q56:P, 7q56:H, 7q56:F, 7q57:P, 7q57:R, 7q57:B, 7q57:D, 7q57:H, 7q57:F, 7q57:J, 7q57:L, 7q57:N, 7q57:T, 1rm3:O, 1rm3:A, 1rm3:B, 1rm4:O, 1rm4:A, 1rm4:B, 1rm5:O, 1rm5:A, 1rm5:B
40 7jwk:C 333 337 0.4524 0.4565 0.4510 2.70e-92 7jwk:A, 7jwk:B, 7jwk:D
41 8hrq:B 336 334 0.4643 0.4643 0.4671 1.19e-90 8hro:A, 8hro:B, 8hrp:A, 8hrp:B, 8hrp:C, 8hrp:D, 8hrp:E, 8hrp:F, 8hrp:G, 8hrp:H, 8hrq:A, 8hrr:A, 8hrr:B, 8hrs:A, 8hrs:B, 8hrs:C, 8hrs:D, 8hrt:A, 8hrt:B, 8hrt:C, 8hrt:D
42 1obf:O 335 331 0.4494 0.4507 0.4562 1.26e-90 1obf:P
43 3b1j:A 338 339 0.4732 0.4704 0.4690 2.35e-90 3b1j:B, 3b1k:A, 3b1k:H, 3b1k:B, 3b1k:G, 3b20:A, 3b20:B, 3b20:O, 3b20:P, 3b20:Q, 3b20:R, 2d2i:A, 2d2i:B, 2d2i:O, 2d2i:P, 2d2i:Q, 2d2i:R, 2duu:A, 2duu:B, 2duu:O, 2duu:P, 2duu:Q, 2duu:R
44 5m6d:A 346 341 0.4583 0.4451 0.4516 2.80e-90 6fzh:A, 6fzh:B, 6ite:P, 6ite:Q, 6ite:R, 6ite:O
45 6fzi:B 332 335 0.4375 0.4428 0.4388 2.03e-89 6fzi:A, 6fzi:C, 6fzi:D
46 7c5o:O 338 335 0.4464 0.4438 0.4478 5.84e-89 7c5f:O, 7c5f:P, 7c5f:Q, 7c5f:R, 7c5g:O, 7c5g:P, 7c5g:Q, 7c5g:R, 7c5h:O, 7c5h:P, 7c5h:Q, 7c5h:R, 7c5i:O, 7c5i:P, 7c5i:Q, 7c5i:R, 7c5j:O, 7c5j:P, 7c5j:Q, 7c5j:R, 7c5k:O, 7c5k:P, 7c5k:Q, 7c5k:R, 7c5l:O, 7c5l:P, 7c5l:Q, 7c5l:R, 7c5m:O, 7c5m:P, 7c5m:Q, 7c5m:R, 7c5n:O, 7c5n:P, 7c5n:Q, 7c5n:R, 7c5o:P, 7c5o:Q, 7c5o:R, 7c5p:O, 7c5p:P, 7c5p:Q, 7c5p:R, 7c5q:O, 7c5q:P, 7c5q:Q, 7c5q:R, 7c5r:O, 7c5r:P, 7c5r:Q, 7c5r:R, 7c7k:O, 7c7k:P, 7c7k:Q, 7c7k:R
47 3k2b:A 337 330 0.4583 0.4570 0.4667 6.84e-87 3k2b:B, 3k2b:C, 3k2b:D, 3k2b:E, 3k2b:F, 3k2b:G, 3k2b:H, 3k2b:O, 3k2b:Q, 6kez:A, 6kez:B, 6kez:C, 6kez:D, 6kez:E, 6kez:F, 6kez:G, 6kez:H, 3qv1:A, 3qv1:D, 3qv1:B, 3qv1:C, 3qv1:F, 3qv1:E, 3rvd:A, 3rvd:D, 3rvd:B, 3rvd:C, 3rvd:O, 3rvd:Q, 3rvd:F, 3rvd:G, 3rvd:E, 3rvd:H
48 7zq3:R 348 337 0.4583 0.4425 0.4570 5.87e-86 7zq3:O, 7zq4:O, 7zq4:R, 7zqk:O, 7zqk:R
49 3lvf:P 338 338 0.4315 0.4290 0.4290 1.47e-85 3hq4:R, 3hq4:O, 3hq4:P, 3hq4:Q, 3k73:Q, 3k73:O, 3k73:P, 3k73:R, 3k9q:Q, 3k9q:O, 3k9q:P, 3k9q:R, 3ksd:Q, 3ksd:R, 3ksd:O, 3ksd:P, 3ksz:O, 3ksz:P, 3ksz:R, 3ksz:Q, 3kv3:O, 3kv3:Q, 3kv3:R, 3kv3:P, 3l4s:Q, 3l4s:P, 3l4s:O, 3l4s:R, 3l6o:Q, 3l6o:P, 3l6o:R, 3l6o:O, 3lc1:P, 3lc1:R, 3lc1:O, 3lc1:Q, 3lc2:O, 3lc2:Q, 3lc2:R, 3lc2:P, 3lvf:R, 3lvf:O, 3lvf:Q, 5t73:A, 5t73:B, 5t73:C, 5t73:D, 3vaz:P, 3vaz:R, 3vaz:O, 3vaz:Q, 3vaz:B, 3vaz:A
50 5utm:A 345 338 0.4315 0.4203 0.4290 7.57e-84 5jy6:A, 5jy6:B, 5jy6:C, 5jy6:D, 5jya:A, 5jya:B, 5jya:C, 5jya:D, 5jye:A, 5jye:C, 4qx6:A, 4qx6:B, 4qx6:C, 4qx6:D, 5utl:A, 5utl:B, 5utl:C, 5utl:D, 5utm:B, 5utm:C, 5utm:D, 5v8x:A, 5v8x:B, 5v8x:C, 5v8x:D, 5y37:A, 5y37:B
51 8hmn:D 340 341 0.4405 0.4353 0.4340 3.97e-83 8hmn:A, 8hmn:B, 8hmn:C, 6iqm:A, 6iqm:B, 6iqm:C, 6iqm:D
52 5ld5:C 342 340 0.4137 0.4064 0.4088 1.12e-81 5ld5:A, 5ld5:B, 5ld5:D
53 7www:A 336 341 0.4256 0.4256 0.4194 4.44e-81
54 5vmt:E 293 332 0.3869 0.4437 0.3916 2.66e-71
55 2xf8:M 327 336 0.3542 0.3639 0.3542 1.12e-70 2xf8:A, 2xf8:C, 2xf8:E, 2xf8:G, 2xf8:I, 2xf8:K, 2xf8:O
56 9iil:A 341 336 0.3780 0.3724 0.3780 5.25e-69 9iil:B, 9iil:C, 9iil:D, 9iim:A, 9iim:C, 9iim:B, 9iim:D, 9ij6:A, 9ij6:C, 9ij6:B, 9ij6:D, 8zn1:A, 8zn1:C, 8zn1:B, 8zn1:D, 8zn4:A, 8zn4:B, 8zn4:C, 8zn4:D, 8zoz:A, 8zoz:C, 8zoz:B, 8zoz:D
57 8jb1:A 468 342 0.3839 0.2756 0.3772 1.02e-58 8jb1:B
58 3tz6:A 342 60 0.0506 0.0497 0.2833 0.008 3vos:A
59 2czc:A 334 31 0.0387 0.0389 0.4194 0.032 2czc:B, 2czc:C, 2czc:D
60 3wyc:A 327 31 0.0506 0.0520 0.5484 0.055 5gz3:A, 5gz3:B, 5gz6:A, 3wyc:B
61 3wgy:B 324 31 0.0446 0.0463 0.4839 0.19 3wgq:A, 3wgz:B
62 4v7n:BB 388 93 0.0893 0.0773 0.3226 0.48 4v7n:AA, 4v7n:AB, 4v7n:AC, 4v7n:AD, 4v7n:AE, 4v7n:AF, 4v7n:AG, 4v7n:AH, 4v7n:AI, 4v7n:AJ, 4v7n:AK, 4v7n:AL, 4v7n:AM, 4v7n:AN, 4v7n:AO, 4v7n:AP, 4v7n:AQ, 4v7n:AR, 4v7n:BA, 4v7n:BC, 4v7n:BD, 4v7n:BE, 4v7n:BF, 4v7n:BG, 4v7n:BH, 4v7n:BI, 4v7n:BJ, 4v7n:BK, 4v7n:BL, 4v7n:BM, 4v7n:BN, 4v7n:BO, 4v7n:BP, 4v7n:BQ, 4v7n:BR
63 6itd:A 328 32 0.0387 0.0396 0.4062 0.74 6k36:A, 6k37:A, 6k38:A
64 8i7h:A 297 31 0.0417 0.0471 0.4516 0.90 8i7h:B, 8i7h:C, 8i7h:D
65 1ys4:A 348 68 0.0565 0.0546 0.2794 1.2 1ys4:B
66 6c8w:A 357 146 0.1220 0.1148 0.2808 1.9 6c85:A, 6c85:B, 6c8w:B
67 4zic:C 357 120 0.1042 0.0980 0.2917 2.0 4zic:A
68 5mg5:L 396 44 0.0387 0.0328 0.2955 2.0 5mg5:C, 5mg5:O, 5mg5:R
69 6g1h:A 342 34 0.0417 0.0409 0.4118 3.1 6g1m:A, 6g1m:B, 6g1m:C, 6g1m:D
70 3hsk:A 358 177 0.1280 0.1201 0.2429 3.3
71 1dap:A 320 58 0.0536 0.0563 0.3103 3.5 1dap:B, 2dap:A, 3dap:A, 3dap:B, 1f06:A, 1f06:B, 5loa:A, 5loa:B
72 1cf2:P 336 350 0.2351 0.2351 0.2257 6.2 1cf2:R, 1cf2:O, 1cf2:Q
73 1fd8:A 73 64 0.0536 0.2466 0.2812 6.5 3k7r:A, 3k7r:B, 3k7r:C, 3k7r:D, 3k7r:E, 3k7r:F, 3k7r:G, 3k7r:H, 3k7r:I, 3k7r:J, 3k7r:K, 3k7r:L, 5vde:B, 5vde:D, 5vdf:A, 5vdf:C, 5vdf:E, 5vdf:G, 5vdf:H
74 6ttb:A 331 28 0.0476 0.0483 0.5714 7.8
75 8tj5:0 1246 47 0.0476 0.0128 0.3404 8.7 8tj5:Y
76 7zbo:A 348 30 0.0298 0.0287 0.3333 9.9 7r09:A, 7zbo:B, 7zbo:C, 7zbo:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218