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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GKDRTEPVKGFHKAMVKTMSAALKIPHFGYCDEVDLTELVKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNAS
VDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQIRSIFEIATELNRLQKLGSAGQLSTNDLIGGTFTLSNIGSIGGTY
AKPVILPPEVAIGALGTIKALPRFNEKGEVCKAQIMNVSWSADHRIIDGATVSRFSNLWKSYLENPAFMLLDLK

The query sequence (length=234) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2ii3:A 234 234 1.0000 1.0000 1.0000 6.39e-176 2ii3:B, 2ii3:C, 2ii3:D, 2ii3:E, 2ii3:F, 2ii3:G, 2ii3:H, 2ii4:A, 2ii4:B, 2ii4:C, 2ii4:D, 2ii4:E, 2ii4:F, 2ii4:G, 2ii4:H, 2ii5:A, 2ii5:B, 2ii5:C, 2ii5:D, 2ii5:E, 2ii5:F, 2ii5:G, 2ii5:H
2 6zzm:B 238 221 0.3291 0.3235 0.3484 2.29e-37 6zzm:A
3 6zzk:B 241 218 0.3333 0.3237 0.3578 1.93e-36 6zzj:A, 6zzk:A
4 1eaf:A 243 196 0.2991 0.2881 0.3571 7.17e-30
5 8p5r:C 1109 227 0.2393 0.0505 0.2467 7.01e-11 6i2q:A, 6i2r:A, 6i2r:C, 6i2s:A, 8p5r:A, 8p5r:B, 8p5r:D, 8p5r:E, 8p5r:F, 6r2b:A, 6r2b:D, 6r2c:A, 6r2c:B, 6r2c:C, 6r2c:D, 6r2d:A, 6r2d:B, 6r2d:C, 6r2d:D, 2xt6:A, 2xt6:B, 2xta:A, 2xta:B, 2xta:C, 2xta:D, 2y0p:D, 2yic:A, 2yic:B, 2yic:C, 2yic:D, 2yid:A, 2yid:B, 2yid:C, 2yid:D, 3zhq:A, 3zhq:B, 3zhq:C, 3zhq:D, 3zhr:A, 3zhr:B, 3zhr:C, 3zhr:D, 3zhs:A, 3zhs:B, 3zhs:C, 3zhs:D, 3zht:A, 3zht:B, 3zht:C, 3zht:D, 3zhu:A, 3zhu:B, 3zhu:C, 3zhu:D, 3zhv:A, 3zhv:B, 3zhv:C, 3zhv:D
6 8p5s:A 1087 232 0.2222 0.0478 0.2241 8.26e-11 8p5x:A, 8p5x:B, 8p5x:C, 8p5x:D, 8p5x:E, 8p5x:F
7 8p5v:A 1121 235 0.2222 0.0464 0.2213 2.13e-10 8p5t:A, 8p5t:B, 8p5t:C, 8p5t:D, 8p5t:E, 8p5t:F, 8p5u:A, 8p5u:B, 8p5u:C, 8p5u:D, 8p5u:E, 8p5u:F, 8p5v:B, 8p5v:E, 8p5v:D, 8p5v:C, 8p5v:F, 8p5w:A, 8p5w:B, 8p5w:C, 8p5w:D, 8p5w:E, 8p5w:F
8 3w9r:A 171 88 0.0983 0.1345 0.2614 1.1 3oqu:A, 3oqu:B
9 3ju5:C 367 69 0.0897 0.0572 0.3043 1.4 3ju5:A, 3ju6:A
10 5gwo:D 167 88 0.0983 0.1377 0.2614 1.9 5gwo:C, 5gwp:C, 5gwp:D, 5zcg:C, 5zcg:D, 5zch:C, 5zch:D, 5zcl:C, 5zcl:D, 5zcu:C, 5zcu:D
11 8bao:A 368 88 0.0983 0.0625 0.2614 4.6 8bao:B
12 4ejy:A 289 47 0.0556 0.0450 0.2766 5.3 4ejy:B, 4ejz:A, 4ejz:B
13 2i22:B 178 20 0.0342 0.0449 0.4000 9.0 2i22:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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