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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
>protein
GITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCD
MVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVF
SISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTI
KPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIRE
GGRTVGAGVVAKVLG

The query sequence (length=335) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length 		Aligned
length 		Identity
(normalized by query) 		Identity
(normalized by hit) 		Identity (normalized
by aligned length) 		E-value Homologs
to hit
1 3avt:A 1203 331 0.9851 0.2743 0.9970 0.0 7abz:6, 5afi:z, 3agp:A, 3agq:A, 3avu:A, 3avv:A, 3avw:A, 3avx:A, 3avy:A, 7bbn:A, 7bbn:B, 2bvn:A, 2bvn:B, 1efm:A, 1etu:A, 4fwt:A, 2hcj:A, 2hcj:B, 2hdn:A, 2hdn:B, 2hdn:C, 2hdn:D, 2hdn:E, 2hdn:F, 2hdn:G, 2hdn:H, 2hdn:I, 2hdn:J, 2hdn:K, 2hdn:L, 5i4r:C, 5i4r:D, 5i4r:G, 5i4r:H, 3mmp:G, 5opd:A, 5opd:B, 4pc2:A, 4pc2:B, 4pc3:A, 4pc3:B, 4pc6:A, 4pc6:B, 4pc7:A, 3u6b:B, 3u6b:A, 3vnu:A, 3vnv:A, 6wd4:8, 6wd7:8, 6wd9:8, 6wda:8
2 1ob2:A 393 334 0.9970 0.8499 1.0000 0.0 1d8t:A, 1d8t:B, 1dg1:G, 1dg1:H, 1efc:A, 1efc:B, 6eze:A, 6eze:B, 8fr3:A, 8fr3:B, 2fx3:A, 4g5g:A, 8g7p:z, 8g7q:z, 5jbq:A, 5mi3:A, 5mi3:B, 5mi8:A, 5mi8:B, 5mi9:A, 5mi9:B, 4p3y:A, 8qfs:C, 8qhc:C, 3u2q:A, 3u6k:A, 3u6k:B, 5uyk:Z, 5uyl:Z, 5uym:Z, 5uyn:Z, 5uyp:Z, 5uyq:Z, 4v69:AZ, 4v6k:BC, 4v6l:AC, 5wdt:z, 6wd2:8, 6wd3:8, 6wd5:8, 6wd6:8, 6wd8:8, 5we4:z, 5we6:z, 5wf0:z, 5wfk:z, 5wfs:z
3 6gfu:A 386 334 0.8299 0.7202 0.8323 0.0 5w76:A, 5w7q:A
4 4zv4:A 392 337 0.8507 0.7270 0.8457 0.0 4zv4:B
5 6mij:A 388 335 0.8597 0.7423 0.8597 0.0
6 6htw:B 385 334 0.8149 0.7091 0.8174 0.0 6htw:H, 6i8r:A
7 8rdw:H 386 335 0.8269 0.7176 0.8269 0.0 8rd8:H
8 4iw3:B 380 337 0.7881 0.6947 0.7834 0.0 4iw3:K, 4j0q:A, 4j0q:B, 4j0q:C, 4j0q:D, 4j0q:E
9 1b23:P 405 345 0.7463 0.6173 0.7246 0.0 2c77:A, 2c78:A, 1eft:A, 1exm:A, 4h9g:A, 1ha3:A, 4lbv:A, 4lbw:A, 4lby:A, 4lbz:A, 4lc0:A, 1mj1:A, 1ob5:A, 1ob5:C, 1ob5:E, 2p8w:S, 2p8x:S, 2p8z:S, 1ttt:A, 1ttt:B, 1ttt:C, 1tui:A, 1tui:B, 1tui:C, 4v5l:AZ, 4v8q:BZ
10 8v9l:x 387 335 0.7522 0.6512 0.7522 0.0 7vok:A, 7vok:B, 7vok:C, 7vok:D
11 5w75:C 387 334 0.7254 0.6279 0.7275 0.0 5w75:B, 5w75:D, 5w75:A
12 4v5p:AZ 385 342 0.7373 0.6416 0.7222 0.0 1ha3:B, 4v5g:AZ, 4v5g:CZ, 4v5p:CZ, 4v5q:AZ, 4v5q:CZ, 4v5r:AZ, 4v5r:CZ, 4v5s:AZ, 4v5s:CZ, 4v68:AZ
13 7paj:9 393 334 0.6896 0.5878 0.6916 2.11e-175 7pak:9, 7pha:9, 7pi9:9, 7pip:9
14 7vmx:B 359 327 0.7343 0.6852 0.7523 1.17e-170
15 1d2e:A 397 332 0.5522 0.4660 0.5572 5.40e-136 7a5g:Z, 1d2e:B, 1d2e:C, 1d2e:D, 7o9k:t
16 3wy9:A 416 366 0.3970 0.3197 0.3634 8.15e-55 3wy9:B, 3wya:A
17 6ji2:A 432 370 0.3433 0.2662 0.3108 3.00e-44 4cxg:A, 4cxh:A, 6ji2:E, 3vmf:A, 3wxm:A, 3wxm:C, 3wxm:E, 3wxm:G
18 1skq:A 416 363 0.3313 0.2668 0.3058 1.77e-41 1jny:A, 1jny:B, 1skq:B
19 5lzw:jj 425 368 0.3224 0.2541 0.2935 3.02e-38 5lzx:jj, 5lzy:jj, 5lzz:jj
20 5o8w:A 449 374 0.3343 0.2494 0.2995 3.05e-35 2b7b:A, 9bdp:EF1A, 1g7c:A, 1ije:A, 1ijf:A
21 6ra9:B 458 379 0.3254 0.2380 0.2876 7.31e-35 8b6z:A, 4c0s:A, 4c0s:B, 8g5z:EF, 8g60:EF, 8g6j:EF, 5lzs:jj, 6ra9:A, 6zmo:CD
22 5lzb:z 614 332 0.2806 0.1531 0.2831 4.16e-28 5lzc:z, 5lzd:z, 2pjp:A
23 4ac9:C 471 241 0.2239 0.1592 0.3112 3.71e-27 4ac9:A, 4ac9:B, 4aca:B, 4aca:C, 4acb:A, 4acb:B, 4acb:C
24 5lzt:jj 428 279 0.2507 0.1963 0.3011 6.64e-24 4d61:i, 5hxb:X, 5hxb:A, 7nwh:jj, 6xk9:X, 6xk9:A
25 7zjw:E 519 227 0.2119 0.1368 0.3128 1.48e-23 5izl:A, 5izl:B
26 5izm:B 495 223 0.1970 0.1333 0.2960 3.64e-23 5izk:A, 5izm:A
27 2dcu:A 407 263 0.2328 0.1916 0.2966 6.00e-21 2d74:A, 1kjz:A, 1kk0:A, 1kk1:A, 1kk2:A, 1kk3:A
28 4zu9:A 582 242 0.2090 0.1203 0.2893 2.81e-18
29 1s0u:A 391 251 0.2269 0.1944 0.3028 5.98e-18
30 3qsy:A 415 204 0.1940 0.1566 0.3186 1.30e-17 2aho:A, 3cw2:B, 6i5m:A, 5jb3:7, 5jbh:7, 4m0l:A, 4m0l:B, 4m0l:C, 4m0l:D, 4m0l:E, 4m0l:F, 4m2l:A, 4m4s:A, 4nbs:A, 3pen:A, 2pmd:A, 2pmd:B, 4qfm:A, 4qhy:A, 2qmu:A, 2qn6:A, 6r8s:A, 6r8t:A, 4rcy:A, 4rcz:A, 4rd0:A, 4rd1:A, 4rd2:A, 4rd3:A, 4rd4:A, 4rd6:A, 4rjl:A, 3sjz:A, 6sw9:7, 6swc:7, 3v11:A
31 4crn:P 430 280 0.2597 0.2023 0.3107 2.43e-15
32 7ase:5 421 184 0.1701 0.1354 0.3098 2.79e-15
33 8cas:G 396 181 0.1701 0.1439 0.3149 5.55e-15 6fyy:k, 6i3m:O, 6i3m:P, 6i7t:O, 6i7t:P, 3jap:k, 8s8f:k
34 3j81:k 365 175 0.1672 0.1534 0.3200 7.42e-15
35 8rw1:k 470 181 0.1701 0.1213 0.3149 9.22e-15 6fyx:k, 6gsm:k, 6gsn:k, 6qg0:M, 6qg0:N, 6qg1:M, 6qg1:N, 6qg2:M, 6qg3:M, 6qg5:M, 6qg6:M, 6qg6:N, 8s8d:k, 8s8e:k, 8s8g:k, 8s8h:k, 8s8i:k, 8s8j:k
36 1zun:B 394 348 0.2597 0.2208 0.2500 1.29e-14
37 3p27:B 444 286 0.2179 0.1644 0.2552 2.38e-14 3p27:A
38 5m1j:A6 539 267 0.2119 0.1317 0.2659 5.66e-14
39 8pj1:t 472 188 0.1642 0.1165 0.2926 8.97e-14 7d43:P, 6fec:S, 5k0y:S, 6k71:P, 6k72:P, 8oz0:E, 8pj2:t, 8ppl:It, 6yal:B, 6yam:B, 6yan:B
40 7qp6:t 356 185 0.1612 0.1517 0.2919 2.06e-13 7qp7:t, 6ybv:t, 6zmw:t
41 5a9y:A 562 174 0.1672 0.0996 0.3218 1.06e-12 5a9x:A
42 5aa0:BZ 605 199 0.1910 0.1058 0.3216 2.39e-12 5a9z:CA, 4zck:A, 4zcl:A, 4zcl:B, 4zcm:A, 4zcm:B
43 5izk:B 451 235 0.1821 0.1353 0.2596 3.37e-11
44 8qzz:A 433 188 0.1582 0.1224 0.2819 7.68e-11 7a09:Y, 6zp4:Y
45 7pua:IA 704 237 0.1970 0.0938 0.2785 2.22e-10 7pub:IA
46 1r5o:A 409 266 0.1881 0.1540 0.2368 1.08e-09 1r5n:A
47 3izy:P 537 165 0.1701 0.1061 0.3455 3.87e-09
48 6gaw:BC 571 164 0.1612 0.0946 0.3293 8.62e-09 6gaz:BC, 6gb2:BC, 7po2:7, 8qrn:7, 6rw5:7
49 7unv:x 593 80 0.0985 0.0556 0.4125 1.38e-08 7unq:x, 7unr:x, 7unt:x, 7unu:x, 7unw:x
50 3j9y:w 639 102 0.1045 0.0548 0.3431 2.46e-08 5kcs:1w
51 3wnb:A 361 259 0.1791 0.1662 0.2317 4.00e-07 3wnc:A
52 2lkd:A 178 80 0.0955 0.1798 0.4000 1.11e-06
53 4v6v:A1 639 80 0.0806 0.0423 0.3375 5.68e-06
54 5lmv:a 502 81 0.0836 0.0558 0.3457 2.98e-05
55 3vr1:A 516 118 0.1045 0.0678 0.2966 7.60e-05 3vqt:A, 3vqt:B, 3vqt:C, 3vqt:D, 3vr1:B, 3vr1:C, 3vr1:D
56 8fzi:v 525 98 0.0896 0.0571 0.3061 1.02e-04 8fzd:v, 8fzf:v, 8fzg:v, 8fzj:v, 6gwt:w, 6gxm:w, 6gxn:w, 6gxo:w, 6gxp:w, 2h5e:A, 2h5e:B, 6lkq:v, 7m5d:7, 4v85:AW, 4v89:AW, 4v8o:AY
57 3tr5:A 518 80 0.0716 0.0463 0.3000 1.16e-04 3tr5:B, 3tr5:C, 3tr5:D
58 9ax8:z 509 61 0.0746 0.0491 0.4098 1.16e-04 3jcj:f, 3jcn:b, 5me0:W, 5me1:W, 6o7k:f, 6o9k:z
59 5fg3:A 598 201 0.1761 0.0987 0.2935 1.29e-04 5yt0:A
60 5h7l:A 694 93 0.0866 0.0418 0.3118 1.80e-04 5h7k:A, 5h7l:B
61 5h7l:A 694 37 0.0418 0.0202 0.3784 2.9 5h7k:A, 5h7l:B
62 8hl1:AEFG 725 288 0.2090 0.0966 0.2431 2.65e-04 8hl2:AEFG, 8hl3:AEFG, 8hl4:AEFG
63 5imr:C 570 191 0.1463 0.0860 0.2565 5.32e-04
64 5j8b:z 671 191 0.1463 0.0730 0.2565 5.62e-04 5imq:B
65 7pao:9 682 80 0.0806 0.0396 0.3375 6.55e-04 7paq:9, 7par:9, 7pib:9, 7pis:9, 7pit:9
66 5anb:K 1120 86 0.0866 0.0259 0.3372 6.71e-04 5anc:K
67 7syv:x 627 64 0.0746 0.0399 0.3906 0.001 8pj3:0, 8pj4:0, 8pj5:0, 7syw:x, 7syx:x, 7tql:1, 4ujc:AB, 4ujd:BB
68 4fn5:A 670 60 0.0627 0.0313 0.3500 0.001
69 8p2f:E 670 60 0.0687 0.0343 0.3833 0.002 8p2g:E, 8p2h:E
70 2ywf:A 532 229 0.1582 0.0996 0.2314 0.002 2ywg:A, 2ywh:A
71 4w2e:y 644 166 0.1284 0.0668 0.2590 0.002
72 7yyp:A 597 62 0.0627 0.0352 0.3387 0.002 7yzn:A, 7zag:7, 7zah:7, 7zki:7
73 7nsh:BC 700 82 0.0836 0.0400 0.3415 0.002 7l20:w
74 4kjz:C 458 81 0.0866 0.0633 0.3580 0.002 4b43:A, 4b44:A, 4b47:A, 4b48:A, 4kjz:A
75 5ty0:A 378 60 0.0627 0.0556 0.3500 0.003
76 1g7s:A 576 62 0.0627 0.0365 0.3387 0.003 1g7t:A
77 3jce:x 586 282 0.1940 0.1109 0.2305 0.003 3deg:C
78 6vlz:v 712 96 0.0776 0.0365 0.2708 0.006 7a5k:r1, 6vmi:v, 6ydp:BC, 6ydw:BC
79 4ncl:B 435 60 0.0657 0.0506 0.3667 0.006 4ncl:A, 4ncn:A, 4ncn:B, 4tmt:A, 4tmt:B, 4tmv:B, 4tmv:A, 4tmw:A, 4tmw:B, 4tmx:A, 4tmx:B, 4tmz:B, 4tmz:A, 4tn1:B, 4tn1:A
80 7pjx:x 522 60 0.0597 0.0383 0.3333 0.007
81 7n2v:EF 704 60 0.0597 0.0284 0.3333 0.009 3j9z:S1, 3ja1:S3, 7k51:8, 7k52:8, 7k54:8, 7k55:8, 7n2c:EF, 7otc:w, 7pjv:x, 7pjw:x, 7pjy:x, 7pjz:x, 7ss9:8, 7ssd:8, 7ssl:8, 7st7:8, 7ug7:EF, 4v7b:AY, 4v7d:BZ, 4v9o:BV, 4v9o:DV, 4v9o:FV, 4v9o:HV, 4v9p:BV, 4v9p:DV, 4v9p:FV, 4v9p:HV
82 8dmf:A 718 115 0.0896 0.0418 0.2609 0.012 7uvp:A
83 2bv3:A 632 96 0.0806 0.0427 0.2812 0.014 1dar:A
84 7siq:A 524 94 0.0806 0.0515 0.2872 0.014
85 4v9h:AY 622 96 0.0806 0.0434 0.2812 0.014
86 1efg:A 592 76 0.0687 0.0389 0.3026 0.017 2efg:A
87 6uz7:1 600 64 0.0687 0.0383 0.3594 0.018 4v8y:CP
88 5hau:1z 730 76 0.0687 0.0315 0.3026 0.020 2bm0:A, 2bm1:A, 1fnm:A, 6gzq:H1, 6gzx:H1, 6gzx:H2, 6gzz:H1, 6gzz:H2, 5hau:2z, 4m1k:A, 4myt:A, 4myu:A, 2om7:L, 5ot7:U, 6q95:G, 6ucq:1v, 6ucq:2v, 4v5f:AY, 4v5f:CY, 4v5m:AY, 4v5n:AY, 4v6t:AY, 4v8u:AY, 4v8u:CY, 4v90:AY, 4v9j:AY, 4v9j:CY, 4v9k:AY, 4v9k:CY, 4v9l:AY, 4v9l:CY, 4v9m:AY, 4v9m:CY, 4w29:AY, 4w29:CY, 4wpo:BZ, 4wpo:DZ, 4wqf:BZ, 4wqf:DZ, 4wqu:BZ, 4wqu:DZ, 4wqy:BZ, 4wqy:DZ
89 6woo:1 600 64 0.0657 0.0367 0.3438 0.040 4ncf:A, 4ncf:B, 3wbk:A
90 4v8z:CV 568 64 0.0657 0.0387 0.3438 0.043
91 4v6w:Az 837 84 0.0866 0.0346 0.3452 0.056
92 3jb9:B 904 66 0.0687 0.0254 0.3485 0.061
93 8bsi:a 815 93 0.0866 0.0356 0.3118 0.44
94 7old:C 813 72 0.0776 0.0320 0.3611 0.46
95 6u45:A 726 102 0.1104 0.0510 0.3627 0.91 6u43:A, 6u44:A, 6u44:B, 6u45:B
96 8q87:A 857 84 0.0806 0.0315 0.3214 1.1 6d9j:9, 6gz3:Ct, 6gz4:Ct, 6gz5:Ct, 3j7p:4, 7ls1:m, 7ls2:m, 6mtd:v, 6mte:v, 7oyc:v2, 4v6x:Az, 8xsx:CB, 6z6m:CB, 6z6n:CB
97 8cf5:Aa 842 73 0.0746 0.0297 0.3425 1.2 8cdr:Aa, 8ceh:Aa, 8cg8:Aa, 8civ:Aa, 8cku:Aa, 8cmj:Aa, 2e1r:A, 8eub:DC, 8evq:DC, 8evr:DC, 8evs:DC, 8ewb:DC, 6gq1:AZ, 6gqb:AZ, 6gqv:AX, 5it7:1, 5juo:DC, 5jup:DC, 5jus:DC, 5jut:DC, 5juu:DC, 8k2d:CD, 1n0u:A, 2npf:A, 2npf:B, 7osa:eEF2, 7osm:eEF2, 2p8w:T, 2p8x:T, 2p8y:T, 2p8z:T, 1u2r:A, 4v4b:AT, 1zm2:E
98 6fku:A 511 50 0.0627 0.0411 0.4200 1.2 6fku:B
99 2dy1:A 660 64 0.0507 0.0258 0.2656 1.5 1wdt:A
100 8y0w:CB 768 62 0.0627 0.0273 0.3387 2.6 8y0x:CB
101 7oyd:v 726 62 0.0627 0.0289 0.3387 3.2
102 8ro2:C 908 71 0.0627 0.0231 0.2958 3.4 7aav:r, 7abf:r, 7abg:r, 7abi:r, 6ah0:C, 6ahd:C, 8c6j:C, 8ch6:b, 7dvq:C, 6ff4:B, 6ff7:B, 9fmd:C, 8h6e:5C, 8h6j:5C, 8h6k:5C, 8h6l:5C, 8i0p:C, 8i0r:C, 8i0s:C, 8i0t:C, 8i0u:C, 8i0v:C, 8i0w:C, 6icz:C, 6id0:C, 6id1:C, 8q7q:C, 8q7v:C, 8q7w:C, 8q7x:C, 8q91:C, 6qdv:C, 8qp8:C, 7qtt:b, 6qw6:5C, 6qx9:5C, 8rc0:C, 7w59:C, 7w5a:C, 7w5b:C, 5xjc:C, 8y6o:D, 5yzg:C, 5z56:C, 5z57:C, 5z58:C, 6zym:B
103 8ro0:C 898 57 0.0507 0.0189 0.2982 4.7 8ro1:C
104 1u0l:A 278 93 0.0866 0.1043 0.3118 4.8 1u0l:B, 1u0l:C
105 6ruz:A 443 41 0.0448 0.0339 0.3659 4.9 6ruz:B, 6ruz:C, 6ruz:D, 6rvb:A, 6rvb:B, 6rvb:C, 6rvb:D, 6rvh:A, 6rvh:B, 6rvh:C, 6rvh:D
106 7xgt:B 275 86 0.0687 0.0836 0.2674 6.0 7xgt:A
107 8k5q:A 163 96 0.0806 0.1656 0.2812 7.6
108 4bac:A 368 46 0.0388 0.0353 0.2826 9.1 7adu:A, 7adv:A, 7adv:B, 4bac:B, 4bdy:A, 4bdz:A, 4be0:A, 4be1:A, 4be1:B, 4be2:A, 4be2:B, 3dlr:A, 4e7h:A, 4e7i:A, 4e7i:B, 4e7j:A, 4e7k:A, 4e7k:B, 4e7l:A, 4e7l:B, 5frm:A, 5frn:A, 5fro:A, 5fro:B, 4ikf:A, 3l2q:A, 3l2r:A, 3l2r:B, 3l2u:A, 3l2u:B, 3l2v:A, 3l2v:B, 3l2w:A, 3l2w:B, 5mma:A, 5mma:B, 5mmb:A, 5mmb:B, 5no1:A, 5no1:B, 3os0:A, 3os0:B, 3os1:A, 3os1:B, 3os2:A, 3oy9:A, 3oy9:B, 3oya:A, 3oya:B, 3oyb:A, 3oyb:B, 3oyc:A, 3oyd:A, 3oyd:B, 3oye:A, 3oye:B, 3oyf:A, 3oyf:B, 3oyg:A, 3oyg:B, 3oyh:A, 3oyh:B, 3oyi:A, 3oyi:B, 3oyj:A, 3oyj:B, 3oyk:A, 3oyk:B, 3oyl:A, 3oyl:B, 3oym:A, 3oym:B, 3oyn:A, 6rny:K, 6rny:O, 3s3m:A, 3s3n:A, 3s3o:A, 5uop:A, 5uoq:A, 2x6n:A, 2x6n:B, 2x6n:C, 2x6n:D, 2x6n:E, 2x6n:F, 2x6s:A, 2x6s:B, 2x6s:C, 2x6s:D, 2x6s:E, 2x6s:F, 4ztf:A, 4ztj:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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