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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAEKLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCT
LPSKKEVERSRRERRQANLLKGKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKA
GIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYMCILSGCAYLSSLRGIGLAKACKV
LRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLSYAGQYVDDSI
ALQIALGNKDINTFEQIDDYNPDTLY

The query sequence (length=346) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7mxw:Z 350 344 0.9913 0.9800 0.9971 0.0 7mxq:Z, 7mxr:Z, 7mxs:Z, 7mxt:Z, 7mxu:Z, 7mxv:Z, 7mxx:Z, 3qe9:Y, 3qe9:Z, 3qea:Z, 3qeb:Z, 5uzv:Z, 5v04:Z, 5v05:Z, 5v06:Z, 5v07:Z, 5v08:Z, 5v09:Z, 5v0a:Z, 5v0b:Z, 5v0c:Z, 5v0d:Z, 5v0e:Z
2 5k97:A 341 302 0.2659 0.2698 0.3046 2.40e-21 5kse:A, 3q8k:A, 3q8l:A, 3q8m:B, 3q8m:A, 5um9:A
3 4q0z:A 322 241 0.1879 0.2019 0.2697 1.10e-18 4q0w:A, 4q0z:B, 4q0z:E, 4q0z:F
4 5zog:A 316 301 0.2399 0.2627 0.2757 7.05e-18 1ul1:X, 5zoe:A, 5zof:A
5 1a76:A 315 254 0.1965 0.2159 0.2677 4.42e-16 1a77:A
6 4q0w:B 301 241 0.1676 0.1927 0.2407 8.90e-15 4q0r:A, 4q10:A, 4q10:B
7 5fv7:A 283 296 0.2428 0.2968 0.2838 9.61e-15 5fv7:B
8 1rxv:A 305 324 0.2457 0.2787 0.2623 2.51e-13 1rxv:B, 1rxw:A
9 5zod:A 260 296 0.2254 0.3000 0.2635 1.88e-11
10 6tux:A 330 276 0.1936 0.2030 0.2428 9.40e-11 6tuw:A, 6tux:B
11 6grd:A 407 240 0.1618 0.1376 0.2333 2.49e-06 5cnq:A, 5co8:C, 5co8:A, 6grb:A, 6grc:A
12 5t9j:B 391 259 0.1561 0.1381 0.2085 1.66e-04 5t9j:A
13 5w4l:G 357 197 0.1301 0.1261 0.2284 0.092 6bf4:G, 8dcq:A, 4dko:A, 4dko:C, 4dkp:A, 4dkp:C, 4dkq:A, 4dkr:A, 4dkr:C, 4dku:A, 4dku:B, 4dkv:A, 4dkv:B, 4dvs:A, 4dvs:B, 4dvt:A, 4dvt:B, 4dvv:A, 4dvv:B, 4dvw:A, 4dvw:B, 4dvx:A, 4dvx:B, 8f9z:A, 8fa0:A, 8gcz:A, 8gd0:A, 8gd1:A, 8gd3:A, 8gd5:A, 8gdj:A, 8gdk:A, 8gjt:A, 4i54:A, 4i54:B, 5kjr:G, 4lsq:G, 6mfp:G, 6mfp:A, 6mg7:G, 7n8q:G, 3ngb:G, 3ngb:A, 3ngb:D, 3ngb:I, 6one:A, 6onf:A, 6onh:A, 6onv:A, 6ooo:A, 6p9n:A, 4rfn:G, 4rfn:A, 4rfo:G, 4rz8:A, 4rz8:B, 4rz8:C, 4rz8:D, 3se9:G, 5u6e:A, 5u6e:B, 5uem:G, 6usw:A, 6ut1:A, 5w4l:A, 6w4m:G
14 1j5p:A 235 30 0.0376 0.0553 0.4333 0.75 1h2h:A
15 7ezx:e2 248 58 0.0520 0.0726 0.3103 4.3 7ezx:eR, 6kgx:e3, 6kgx:eD, 7y4l:eK, 7y4l:e1, 7y5e:eA, 7y5e:e7, 7y7a:eD, 7y7a:e5, 7y7a:eg, 7y7a:ei
16 5ded:A 196 73 0.0578 0.1020 0.2740 7.0 5ded:D, 5ded:B, 5ded:C, 5ded:E, 5ded:F, 5ded:G, 5ded:H, 5f2v:V, 5f2v:X, 5f2v:T, 5f2v:S, 5f2v:Y, 5f2v:O, 5f2v:Z, 5f2v:W, 5f2v:U, 5f2v:P, 5f2v:R, 5f2v:Q
17 4pab:B 824 103 0.0780 0.0328 0.2621 7.1 5l46:A, 5l46:B, 4p9s:A, 4p9s:B, 4paa:A, 4paa:B, 4pab:A
18 1lvl:A 458 101 0.0694 0.0524 0.2376 7.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218