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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GIPHDHYEPRTGIEKWLHSRLPIVALAYDTIMIPTPRNLNWMWIWGVVLAFCLVLQIVTGIVLAMHYTPHVDLAFASVEH
IMRNVNGGFMLRYLHANGASLFFIAVYLHIFRGLYYGSYKAPREVTWIVGMLIYLAMMATAFMGYVLPWGQMSFWGATVI
TGLFGAIPGIGHSIQTWLLGGPAVDNATLNRFFSLHYLLPFVIAALVAIHIWAFHSTGNNNPTGVEVRRTSKAEAQKDTV
PFWPYFIIKDVFALAVVLLVFFAIVGFMPNYLGHPDNYIEANPLRTPAHIVPEWYFLPFYAILRAFTADVWVVQIANFIS
FGIIDAKFFGVLAMFGAILVMALVPWLDTSPVRSGRYRPMFKIYFWLLAADFVILTWVGAQQTTFPYDWISLIASAYWFA
YFLVILPILGAIEKPVAPPATIEEDFNA

The query sequence (length=428) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8asi:B 433 428 0.9977 0.9861 0.9977 0.0 8asi:F, 8asj:B, 8asj:F, 2fyn:A, 2fyn:D, 2fyn:G, 2fyn:J, 2fyn:M, 2fyn:P, 5kkz:A, 5kkz:E, 5kkz:K, 5kkz:O, 5kli:A, 5kli:E, 5kli:K, 5kli:O, 6nhh:A, 6nhh:E, 6nin:A, 6nin:E, 6nin:K, 6nin:O, 6nin:S, 6nin:W, 2qjk:A, 2qjk:D, 2qjk:G, 2qjk:J, 2qjk:M, 2qjk:P, 2qjp:A, 2qjp:D, 2qjp:G, 2qjp:J, 2qjy:A, 2qjy:D, 2qjy:G, 2qjy:J, 2qjy:M, 2qjy:P, 7tce:A, 7tce:E, 7tce:K, 7tce:O, 7tlj:A, 7tlj:E
2 1zrt:C 431 428 0.8388 0.8329 0.8388 0.0 6xi0:C, 6xi0:P, 6xkt:C, 6xkt:P, 6xku:C, 6xku:P, 6xkv:C, 6xkv:P, 6xkw:C, 6xkw:P, 6xkx:C, 6xkx:P, 6xkz:C, 6xkz:P, 1zrt:P
3 2yiu:A 428 428 0.8505 0.8505 0.8505 0.0 2yiu:D
4 7jrg:C 388 391 0.4743 0.5232 0.5192 6.78e-127 8bel:C, 8bel:M, 8bpx:AC, 8bpx:BC, 8bq5:AC, 8bq5:BC, 8bq6:AC, 8bq6:BC, 8e73:C, 8e73:O, 7jrg:O, 7jrp:C, 7jrp:O
5 7rje:K 384 381 0.4182 0.4661 0.4698 3.50e-122 7rja:K, 7rja:T, 7rjb:K, 7rjc:K, 7rjd:K, 7rje:T
6 3cwb:C 380 394 0.4299 0.4842 0.4670 2.85e-120 1bcc:C, 2bcc:C, 3bcc:C, 3cwb:P, 3h1h:C, 3h1h:P, 3h1i:C, 3h1i:P, 3h1j:C, 3h1j:P, 3h1k:C, 3h1k:P, 3h1l:C, 3h1l:P, 3l70:C, 3l70:P, 3l71:C, 3l71:P, 3l72:C, 3l72:P, 3l73:C, 3l73:P, 3l74:C, 3l74:P, 3l75:C, 3l75:P, 3tgu:C, 3tgu:P, 4u3f:C, 4u3f:P
7 7o37:C 380 386 0.4416 0.4974 0.4896 5.73e-119 8iao:AC, 8iao:Ac, 8iar:AC, 8iar:Ac, 8ib4:AC, 8ib4:Ac, 8ib7:AC, 8ib7:Ac, 8ib9:AC, 8ib9:Ac, 8ibc:AC, 8ibc:Ac, 8ibd:AC, 8ibd:Ac, 8ibg:AC, 8ibg:Ac, 8ic2:AC, 8ic2:Ac, 8ic5:AC, 8ic5:Ac, 7o37:N, 7o3c:C, 7o3c:N, 7o3e:C, 7o3e:N, 7o3h:C, 7o3h:N, 8pw5:C, 8pw5:N, 8pw6:C, 8pw6:N, 8pw7:C, 8pw7:N
8 3cx5:C 385 381 0.4252 0.4727 0.4777 1.14e-114 3cx5:N, 3cxh:C, 3cxh:N, 8e7s:J, 8e7s:j, 8ec0:J, 8ec0:j, 1ezv:C, 6giq:C, 6giq:N, 6hu9:C, 6hu9:N, 2ibz:C, 1kb9:C, 1kyo:C, 1kyo:N, 1p84:C, 4pd4:C, 6t0b:C, 6t0b:N, 6t15:C, 6t15:N, 6ymx:C, 6ymx:N
9 1be3:C 379 406 0.4556 0.5145 0.4803 4.42e-114 2a06:C, 2a06:P, 1bgy:C, 1bgy:O, 4d6t:C, 4d6t:P, 4d6u:C, 4d6u:P, 7dgq:m, 7dgq:y, 7dgr:m, 7dgr:y, 7dgs:m, 7dgs:y, 7dkf:C1, 7dkf:O1, 6fo0:P, 6fo0:C, 6fo2:P, 6fo2:C, 6fo6:C, 6fo6:P, 2fyu:C, 5gpn:C, 5gpn:O, 5gup:w, 5gup:7, 6haw:C, 8iog:A, 8iog:a, 5j4z:AC, 5j4z:AN, 5j7y:AC, 5j7y:AN, 5j8k:AC, 5j8k:AN, 5klv:C, 1l0l:C, 1l0n:C, 5luf:b, 5luf:o, 6nhg:C, 5nmi:C, 5nmi:P, 1ntk:C, 1ntm:C, 1ntz:C, 1nu1:C, 5okd:C, 8p65:C, 8p65:P, 1pp9:C, 1pp9:P, 1ppj:C, 1ppj:P, 6q9e:b1, 6q9e:b2, 6qbx:b1, 6qbx:b2, 1qcr:C, 6qc2:b1, 6qc2:b2, 6qc3:b1, 6qc3:b2, 6qc4:b1, 6qc4:b2, 7r3v:C, 1sqb:C, 1sqp:C, 1sqq:C, 1sqv:C, 1sqx:C, 7tay:C, 7tz6:C, 7tz6:P, 8ugd:3C, 8ugd:3P, 8uge:3C, 8uge:3P, 8ugf:3C, 8ugf:3P, 8ugg:3C, 8ugg:3P, 8ugh:3C, 8ugh:3P, 8ugi:3C, 8ugi:3P, 8ugj:3C, 8ugj:3P, 8ugk:3C, 8ugk:3P, 8ugn:3C, 8ugn:3P, 8ugr:3C, 8ugr:3P, 8ugr:6C, 8ugr:6P, 6xvf:C, 2ybb:C, 2ybb:c, 6zfs:C, 6zft:C, 6zfu:C
10 8ab6:C 383 381 0.4182 0.4674 0.4698 1.17e-112 8ab6:N, 8ab7:C, 8ab7:N, 8ab8:C, 8ab8:N, 8ab9:C, 8ab9:N, 8aba:C, 8aba:N, 8abb:C, 8abb:N, 8abe:C, 8abe:N, 8abf:C, 8abf:N, 8abg:C, 8abg:N, 8abh:C, 8abh:N, 8abi:C, 8abi:N, 8abj:C, 8abj:N, 8abk:C, 8abk:N, 8abl:C, 8abl:N, 8abm:C, 8abm:N, 8ac3:C, 8ac3:N, 8ac4:C, 8ac4:N, 8ac5:C, 8ac5:N
11 5xte:J 378 384 0.4299 0.4868 0.4792 1.85e-112 5xte:V, 5xth:AJ, 5xth:AV, 5xti:AJ, 5xti:AV
12 8smr:I 403 414 0.4229 0.4491 0.4372 1.00e-109 8smr:D, 8snh:I, 8snh:D
13 8q1b:C 387 400 0.4533 0.5013 0.4850 1.37e-109 8q1b:N
14 6kls:B 395 415 0.3505 0.3797 0.3614 9.40e-70 6kls:E, 6klv:B, 6klv:E
15 8iuf:QC 364 262 0.2383 0.2802 0.3893 7.44e-50 8iuf:Qc, 8iuj:QC, 8iuj:Qc
16 1q90:B 212 211 0.1776 0.3585 0.3602 2.47e-42
17 7r0w:I 222 214 0.1706 0.3288 0.3411 4.94e-42 7r0w:A, 7zxy:A, 7zxy:I
18 6rqf:I 215 213 0.1706 0.3395 0.3427 6.21e-40 7qrm:I, 7qrm:A, 6rqf:A, 7zyv:I, 7zyv:A
19 2e74:A 215 211 0.1706 0.3395 0.3460 1.75e-39 2d2c:A, 2d2c:N, 2e75:A, 2e76:A, 4h0l:A, 4h13:A, 4h44:A, 4i7z:A, 4ogq:A, 4pv1:A, 1vf5:A, 1vf5:N, 2zt9:A
20 7q21:b 534 190 0.1168 0.0936 0.2632 2.68e-17 7q21:B, 7qhm:B, 7qhm:O, 7qho:B, 7qho:O
21 7e1v:N 524 191 0.1192 0.0973 0.2670 2.32e-14 7e1v:B, 7e1w:N, 7e1w:B, 7e1x:N, 7e1x:B, 8hcr:B, 8hcr:N
22 6hwh:b 536 191 0.1168 0.0933 0.2618 9.60e-14 6adq:B, 6adq:N, 6hwh:Y, 8ovc:H, 8ovc:N, 8ovd:N, 8ovd:H, 7rh5:E, 7rh5:F, 7rh6:F, 7rh6:E, 7rh7:E, 7rh7:F
23 8b6j:C 426 287 0.1542 0.1549 0.2300 5.37e-11 8b6j:c, 8bqs:C, 8bqs:c, 8gym:qc, 8gym:qC, 8gym:QC, 8gym:Qc, 8gzu:qC, 8gzu:qc, 8gzu:QC, 8gzu:Qc, 7tgh:3C, 7tgh:3c
24 1q90:D 156 137 0.0935 0.2564 0.2920 6.32e-06
25 2e74:B 160 152 0.0958 0.2562 0.2697 8.43e-04 2d2c:B, 2d2c:O, 2e75:B, 2e76:B, 4h0l:B, 4h13:B, 4h44:B, 4i7z:B, 4ogq:B, 4pv1:B, 1vf5:B, 1vf5:O, 2zt9:B
26 6rqf:J 160 61 0.0467 0.1250 0.3279 0.001 7qrm:B, 7qrm:J, 6rqf:B, 7zyv:J, 7zyv:B
27 7r0w:J 159 81 0.0561 0.1509 0.2963 0.018 7r0w:B, 7zxy:B, 7zxy:J
28 6f8z:A 715 149 0.0841 0.0503 0.2416 0.17 6f8z:B, 6f8z:C, 6f90:A, 6f90:B, 6f90:C
29 4a6g:A 368 81 0.0491 0.0571 0.2593 2.5 4a6g:B, 4a6g:C, 4a6g:D, 5fjo:A, 5fjo:B, 5fjp:A, 5fjp:B, 5fjp:C, 5fjp:D, 5fjr:A, 5fjr:B, 5fjr:C, 5fjr:D, 5fjt:A, 5fjt:B, 5fjt:C, 5fjt:D, 5fju:A, 5fju:B, 5fju:C, 5fju:D, 7s8w:A, 7s8w:B, 7s8w:C, 7s8w:D, 1sja:A, 1sja:B, 1sja:C, 1sja:D, 1sjb:A, 1sjb:B, 1sjb:C, 1sjb:D, 1sjc:A, 1sjc:B, 1sjc:C, 1sjc:D, 1sjd:A, 1sjd:B, 1sjd:C, 1sjd:D
30 3nj3:A 327 66 0.0491 0.0642 0.3182 3.2 3nj3:B, 1vbr:A, 1vbr:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218