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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GHMKNILVTGGLGFIGSNFVNHISSKYDNVNIYVYDIGDYCASVENVEWNNRTKLIKGDIRNFDLIMHTLTEHEIDTIVH
FAAHSHVDNSFKNSLAFTETNVFGTHVLLECSRMYGKLKLFFHMSTDEVYGEIDTTDTSREVSLLCPTNPYAATKAGAEH
IVKSYFLSYKLPIIIARCNNVYGRNQYPEKLIPKFICSLLDGKKLHIQGTGNSRRNFIHAIDVADAVDLVINNGVIGETY
NIGVTNEHSVLDVAQILCDIAGVNLENQLEYVPDRLFNDFRYNITNDKIKSLGWEQSRKDFKKELVELFDWYKVNRHRY

The query sequence (length=319) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6vlo:A 319 319 1.0000 1.0000 1.0000 0.0 6vlo:B, 6vlo:C, 6vlo:D
2 6bi4:C 311 319 0.3856 0.3955 0.3856 1.00e-67 6bi4:B, 6bi4:D, 6bi4:A
3 1r66:A 322 320 0.3981 0.3944 0.3969 3.08e-64 1r6d:A
4 8sk0:B 330 324 0.3605 0.3485 0.3549 5.94e-64 8shh:A, 8shh:B, 8sk0:A
5 1keu:A 361 336 0.3887 0.3435 0.3690 1.81e-63 1g1a:A, 1g1a:B, 1g1a:C, 1g1a:D, 1keu:B, 1kew:A, 1kew:B
6 8du1:A 361 341 0.3918 0.3463 0.3666 8.27e-61 8du1:B, 8du1:C, 8du1:D
7 1bxk:B 344 330 0.3762 0.3488 0.3636 1.73e-59 1bxk:A
8 1ker:B 347 330 0.3668 0.3372 0.3545 1.05e-57 1kep:A, 1kep:B, 1ker:A, 1ket:A, 1ket:B, 1oc2:A, 1oc2:B
9 2hun:A 329 315 0.3668 0.3556 0.3714 5.49e-57 2hun:B
10 6zll:A 321 280 0.2978 0.2960 0.3393 2.01e-32 6zl6:A, 6zl6:B, 6zla:A, 6zla:B, 6zla:C, 6zla:D, 6zld:A, 6zld:B, 6zlj:A, 6zlj:B, 6zlk:A, 6zlk:B, 6zlk:C, 6zlk:D, 6zll:B, 6zll:C, 6zll:D
11 4zrn:A 309 300 0.2978 0.3074 0.3167 2.31e-27 4zrm:A, 4zrm:B, 4zrn:B
12 3vps:A 303 254 0.2445 0.2574 0.3071 3.05e-27 3vps:B
13 8vr2:B 321 329 0.2853 0.2835 0.2766 1.11e-26 8vr2:A, 8vr2:C, 8vr2:D
14 2p5u:A 311 304 0.2696 0.2765 0.2829 1.01e-24 2p5u:B, 2p5u:C, 2p5u:D, 2p5y:A
15 6bwl:A 313 262 0.2508 0.2556 0.3053 3.01e-24
16 6dnt:A 310 319 0.2853 0.2935 0.2853 2.48e-23
17 2b69:A 312 302 0.2602 0.2660 0.2748 1.85e-22 4gll:A, 4gll:B
18 6pnl:A 336 328 0.2884 0.2738 0.2805 3.31e-22 6pmh:A
19 2c20:A 329 338 0.2853 0.2766 0.2692 4.67e-22 2c20:B, 2c20:C, 2c20:D, 2c20:E, 2c20:F
20 3ehe:A 290 317 0.2853 0.3138 0.2871 2.88e-21 3ehe:B
21 8wov:B 341 347 0.2978 0.2786 0.2738 1.61e-20 8wop:A, 8wop:B, 8wov:A, 8wow:A, 8wow:B
22 2q1s:A 336 325 0.2665 0.2530 0.2615 7.70e-20 2pzj:A, 2q1t:A, 2q1u:A, 2q1u:B
23 2pk3:A 309 314 0.2665 0.2751 0.2707 3.00e-19 2pk3:B
24 7k3p:A 329 331 0.2790 0.2705 0.2689 7.46e-19 7k3p:B
25 7kn1:A 336 341 0.2853 0.2708 0.2669 1.41e-18 7kn1:B
26 6x3b:A 300 304 0.2194 0.2333 0.2303 3.88e-18 6x3b:B, 6x3b:C, 6x3b:D
27 1sb8:A 341 288 0.2476 0.2317 0.2743 8.58e-18 1sb9:A
28 7xpo:A 344 350 0.2947 0.2733 0.2686 1.63e-17 7xpo:B, 7xpp:B, 7xpp:A, 7xpq:A, 7xpq:B
29 4lk3:B 274 298 0.2508 0.2920 0.2685 1.80e-17 4lk3:A, 4lk3:C, 4lk3:D, 4lk3:E, 4lk3:F, 4m55:A, 4m55:B, 4m55:C, 4m55:D
30 1orr:A 338 268 0.2163 0.2041 0.2575 2.30e-17 1orr:B, 1orr:C, 1orr:D
31 1z45:A 674 339 0.2947 0.1395 0.2773 2.44e-17
32 6kv9:A 299 315 0.2602 0.2776 0.2635 4.51e-17 6kvc:A
33 5u4q:A 321 337 0.2727 0.2710 0.2582 7.78e-17
34 1a9y:A 338 286 0.2445 0.2308 0.2727 7.26e-16 1a9z:A, 5gy7:A, 5gy7:B, 1kvq:A, 1kvr:A, 1kvs:A, 1kvt:A, 1kvu:A, 1lrj:A, 1lrk:A, 1lrl:A, 1nah:A, 1nai:A, 1uda:A, 1udb:A, 1udc:A, 2udp:A, 2udp:B, 1xel:A
35 6k0g:A 335 318 0.2571 0.2448 0.2579 3.48e-15 6k0h:A, 6k0i:A
36 4twr:A 325 308 0.2476 0.2431 0.2565 3.57e-15 4wok:A
37 3lu1:A 336 324 0.2602 0.2470 0.2562 6.56e-15 3lu1:B, 3lu1:C, 3lu1:D, 3ru7:A, 3ru7:B, 3ru7:C, 3ru7:D, 3ru9:A, 3ru9:B, 3ru9:C, 3ru9:D, 3rua:A, 3rua:B, 3rua:C, 3rua:D, 3ruc:A, 3ruc:B, 3ruc:C, 3ruc:D, 3rud:A, 3rud:B, 3rud:C, 3rud:D, 3rue:A, 3rue:B, 3rue:S, 3rue:b, 3ruf:A, 3ruf:B, 3ruf:S, 3ruf:b, 3ruh:A, 3ruh:B, 3ruh:C, 3ruh:D
38 7yst:A 312 311 0.2727 0.2788 0.2797 1.06e-14 7ys8:A, 7ys8:B, 7ys9:A, 7ys9:B, 7ysa:A, 7ysa:B, 7ysm:A, 7ysm:B, 7yst:B, 7ysy:A, 7ysy:B, 7yt0:A, 7yt0:B
39 8v4h:B 342 301 0.2414 0.2251 0.2558 1.68e-14 8v4g:A, 8v4g:B, 8v4h:A
40 1wvg:A 352 261 0.2006 0.1818 0.2452 1.72e-14 1wvg:B
41 6wj9:B 308 279 0.2163 0.2240 0.2473 1.27e-13 6wj9:A, 6wja:A, 6wja:B, 6wjb:A, 6wjb:B
42 5u4q:B 304 272 0.2163 0.2270 0.2537 5.00e-13
43 1gy8:C 370 309 0.2445 0.2108 0.2524 6.67e-13 2cnb:A, 2cnb:B, 2cnb:C, 2cnb:D, 1gy8:A, 1gy8:B, 1gy8:D
44 3aw9:A 304 331 0.2790 0.2928 0.2689 1.08e-12 3aw9:B, 3aw9:C, 3icp:A, 3ko8:A
45 6bwc:C 327 307 0.2288 0.2232 0.2378 1.50e-11 6bwc:A, 6bwc:B, 6bwc:D, 6bwc:E, 6bwc:F
46 4lis:A 364 374 0.3041 0.2665 0.2594 1.79e-11 4lis:B, 4lis:C
47 1rkx:C 351 327 0.2194 0.1994 0.2141 2.08e-11 1rkx:A, 1rkx:B, 1rkx:D
48 2pzm:A 316 318 0.2320 0.2342 0.2327 2.57e-11 2pzk:A, 2pzk:B, 2pzl:A, 2pzl:B, 2pzm:B
49 7us5:A 346 323 0.2414 0.2225 0.2384 2.68e-11 7us5:B, 7us5:C, 7us5:D
50 2z1m:A 338 274 0.1975 0.1864 0.2299 3.38e-11 2z1m:D, 2z95:A, 2z95:D
51 6jyg:D 307 310 0.2414 0.2508 0.2484 9.95e-10 6jyg:A, 6jyg:B, 6jyg:C, 6jyg:E, 6jyg:F
52 3a1n:A 315 244 0.1912 0.1937 0.2500 2.53e-09 3a1n:B, 3a4v:A, 3a4v:B, 3a9w:A, 3a9w:B, 3ajr:A, 3ajr:B
53 1i3k:A 347 344 0.2476 0.2277 0.2297 2.87e-09 1ek5:A, 1ek6:A, 1ek6:B, 1hzj:A, 1hzj:B, 1i3k:B, 1i3l:A, 1i3l:B, 1i3m:A, 1i3m:B, 1i3n:A, 1i3n:B
54 3enk:A 340 341 0.2665 0.2500 0.2493 6.08e-09 3enk:B
55 7anc:B 314 190 0.1693 0.1720 0.2842 3.14e-08
56 7kf3:A 362 218 0.1661 0.1464 0.2431 3.36e-08 7kf3:B, 7kf3:C, 7kf3:D
57 5uzh:A 345 187 0.1567 0.1449 0.2674 5.32e-08
58 2x6t:G 308 324 0.2445 0.2532 0.2407 3.29e-07 1eq2:B, 1eq2:D, 1eq2:E, 1eq2:F, 1eq2:G, 1eq2:H, 1eq2:I, 1eq2:J, 2x6t:A, 2x6t:B, 2x6t:C, 2x6t:D, 2x6t:E, 2x6t:F, 2x6t:H, 2x6t:I, 2x6t:J, 2x86:A, 2x86:B, 2x86:C, 2x86:D, 2x86:E, 2x86:F, 2x86:G, 2x86:H, 2x86:I, 2x86:J, 2x86:K, 2x86:L, 2x86:M, 2x86:N, 2x86:O, 2x86:P, 2x86:Q, 2x86:R, 2x86:S, 2x86:T
59 5in4:A 355 210 0.1693 0.1521 0.2571 6.66e-07 6gpj:A, 6gpj:B, 6gpj:D, 6gpj:C, 6gpk:A, 6gpk:B, 6gpk:C, 6gpk:D, 6gpl:B, 6gpl:E, 6gpl:C, 6gpl:D, 5in4:B, 5in4:C, 5in4:D, 5in5:A, 5in5:B, 5in5:C, 5in5:D, 6q94:B, 6q94:A, 6q94:C, 6q94:E, 6q94:D, 6q94:F, 6q94:G, 6q94:H, 1t2a:A, 1t2a:D, 1t2a:B, 1t2a:C
60 2gn4:A 329 133 0.1160 0.1125 0.2782 1.01e-06 2gn4:B, 2gn6:A, 2gn6:B, 2gn8:A, 2gn8:B, 2gn9:A, 2gn9:B, 2gna:A, 2gna:B
61 1n7g:B 336 236 0.1755 0.1667 0.2373 1.31e-06 1n7g:A, 1n7g:C, 1n7g:D, 1n7h:A, 1n7h:B
62 7cxt:A 348 128 0.1191 0.1092 0.2969 1.65e-06 7anc:A, 7cxt:B, 7m13:A, 7m13:B
63 5y1f:A 311 166 0.1505 0.1543 0.2892 1.71e-06 5y1e:A, 5y1g:A
64 3sxp:D 314 268 0.2163 0.2197 0.2575 2.42e-06 3sxp:A, 3sxp:B, 3sxp:C, 3sxp:E
65 2q1w:A 300 233 0.1787 0.1900 0.2446 3.65e-06 2q1w:B, 2q1w:C
66 6vo6:D 311 334 0.2571 0.2637 0.2455 6.13e-06 6vo6:A, 6vo6:B, 6vo6:C, 6vo8:A, 6vo8:B
67 7cgv:A 310 166 0.1317 0.1355 0.2530 6.39e-06 7cgv:B, 7cgv:C, 7cgv:D
68 5z75:A 306 168 0.1348 0.1405 0.2560 7.76e-06 5z75:B, 5z75:D
69 1eq2:A 273 258 0.2132 0.2491 0.2636 2.30e-05 1eq2:C
70 5bju:A 340 264 0.1975 0.1853 0.2386 3.82e-05 5bju:B, 5bjv:A, 5bjv:B, 5bjw:A, 5bjw:B, 5bjx:A, 5bjx:B, 5bjy:A, 5bjy:B
71 5k4w:C 321 182 0.1473 0.1464 0.2582 5.61e-05 5k4q:A, 5k4q:B, 5k4q:C, 5k4q:D, 5k4q:E, 5k4q:F, 5k4u:A, 5k4u:C, 5k4v:A, 5k4v:C, 5k4w:A, 5k4y:A, 5k4y:B, 5k4y:C, 5k4y:D, 5k4y:E, 5k4y:F, 5k50:A, 5k50:C, 5k50:E, 5k50:G, 5k50:I, 5k50:J, 5lc1:A, 5lc1:B, 5lc1:C, 5lc1:D, 5lc1:E, 5lc1:F
72 4j2o:C 316 232 0.1818 0.1835 0.2500 8.52e-05 4j2o:A, 4j2o:B, 4j2o:D, 4j2o:E, 4j2o:F
73 3w1v:A 347 278 0.2100 0.1931 0.2410 1.69e-04 4g5h:A, 3vvc:A, 3w1v:B
74 2c59:A 364 220 0.1630 0.1429 0.2364 2.13e-04 2c54:A, 2c54:B, 2c59:B, 2c5a:A, 2c5a:B, 2c5e:A, 2c5e:B, 8sg0:A, 8sg0:B, 8skb:A, 8skb:B, 8skb:C, 8skb:D
75 4bkp:C 326 163 0.1129 0.1104 0.2209 2.40e-04 4b8w:A, 4b8w:B, 4b8z:A, 4b8z:B, 4b8z:C, 4b8z:D, 4bkp:A, 4bkp:B, 4bkp:D, 4bl5:A, 4bl5:B, 4bl5:C, 4bl5:D, 4bl5:E, 4bl5:F, 4bl5:G, 4bl5:H, 4bl5:I, 4bl5:J, 4bl5:K, 4bl5:L, 4e5y:A, 4e5y:B, 4e5y:D
76 4ej0:A 330 292 0.2194 0.2121 0.2397 3.11e-04 4ej0:B, 4ej0:C, 4ej0:D, 4ej0:E, 4ej0:F, 4ej0:G, 4ej0:H, 4ej0:I, 4ej0:J
77 8ctr:A 298 158 0.1442 0.1544 0.2911 3.60e-04 8ctr:B, 8ctr:C, 8ctr:D
78 8ewu:B 354 130 0.1034 0.0932 0.2538 5.87e-04 8ewu:A
79 4tqg:A 297 165 0.1379 0.1481 0.2667 6.79e-04
80 4e5y:C 290 155 0.1066 0.1172 0.2194 7.83e-04
81 4u7w:B 394 266 0.1944 0.1574 0.2331 0.001 4u7w:A
82 4id9:B 328 335 0.2508 0.2439 0.2388 0.003 4id9:A, 4idg:A, 4idg:B
83 1i24:A 392 350 0.2320 0.1888 0.2114 0.004 1i2b:A, 1i2c:A, 1qrr:A
84 3m2p:B 255 258 0.1881 0.2353 0.2326 0.008
85 4m55:E 164 127 0.1160 0.2256 0.2913 0.009
86 7epr:B 310 166 0.1160 0.1194 0.2229 0.015 7epr:A, 7epr:C, 7epr:D
87 6ex6:A 634 131 0.1097 0.0552 0.2672 0.031 6ex6:B
88 3vvb:A 270 234 0.1630 0.1926 0.2222 0.033
89 1bsv:A 317 199 0.1379 0.1388 0.2211 0.049 1bws:A, 1e6u:A, 1e7q:A, 1e7r:A, 1e7s:A, 1fxs:A
90 5u9c:A 288 160 0.1191 0.1319 0.2375 0.13 5u9c:C
91 6nbr:A 316 333 0.2445 0.2468 0.2342 0.37 6nbr:B, 6nbr:C, 6nbr:D
92 6d2v:A 315 306 0.2100 0.2127 0.2190 0.85 6d2v:B, 6nd7:A, 6nd7:B
93 3st7:A 369 181 0.1317 0.1138 0.2320 1.2 2zkl:A
94 6jkh:A 212 129 0.0878 0.1321 0.2171 1.2 6jkh:B
95 1kc1:A 298 109 0.0878 0.0940 0.2569 1.4 1kc3:A, 1n2s:A
96 4yr9:A 308 168 0.1191 0.1234 0.2262 1.5 4yr9:B, 4yr9:C, 4yr9:D, 4yr9:E, 4yr9:F
97 3qw9:A 170 65 0.0690 0.1294 0.3385 2.6
98 4wio:A 525 27 0.0408 0.0248 0.4815 2.8 3uow:A
99 3b9o:A 433 70 0.0658 0.0485 0.3000 4.6 3b9o:B
100 2yy7:A 312 305 0.1912 0.1955 0.2000 4.8 2yy7:B
101 4v8p:AF 125 23 0.0376 0.0960 0.5217 5.3 4v8p:DF, 4v8p:FF, 4v8p:HF
102 5ftc:A 431 45 0.0533 0.0394 0.3778 5.9 5fhd:A, 5fhe:A, 5fhf:A, 5ftb:A, 5fte:A, 5ftf:A, 6l3g:A, 6l3g:B
103 3q2q:A 314 66 0.0533 0.0541 0.2576 8.2
104 8j4u:O 585 77 0.0658 0.0359 0.2727 8.8 8j4u:M, 8j4u:N, 8su9:M, 8su9:N, 8su9:O, 8sub:M, 8sub:N, 8sub:O, 8suw:M, 8suw:N, 8suw:O, 8uae:M, 8uae:N, 8uae:O, 8uaf:M, 8uaf:N, 8uaf:O
105 8j4u:P 559 77 0.0658 0.0376 0.2727 8.9 8j4u:Q, 8su9:P, 8su9:Q, 8sub:P, 8sub:Q, 8uae:P, 8uae:Q, 8uaf:P, 8uaf:Q

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218