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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GGSPYLITGIPKDPKHPLPIRKDIDDWYLEQTRIQLTLFVEALTVIQNRPLNDQLSYFRLAGIHGAPWTEWDGVPGGQKD
SKGNPTGFAVHNNYTFPTWHRVYVTLYEQVIYEAMLDFIKQNVPQNGKADWENEAKQWRLPYWDFARFADELRLPILVTM
PMVKVLVPGQPGKQLSKPNPLYRFQMQTLMGTLERPYAITSSFDLPFDKCQSTTKYGLLENYNADVWADGGQNWLRANLA
LNEHPWYQNLDGWDSVPTLQDMTFRLLTTGGLNWGEFSSTRYAPKNWMNLEAIHNNVHNWVGGFMFSRPGRHDLKLWGAG
HMSSVPVAAYDPIFWLHHCNIDRLTAIWQTVNSGSWFNDDKSKVSKDDDLRPFHRFCEKTRKVVFFRSDDVKDWRSLNYD
YAITKDASRIRKEISDLYGQRTKEVYKDFGEEDYILSIRYSRYALGGKPFQINIFFGDVDGKDFYDARSQNFVGSVFNFS
GVLSVSQLPARLAVHYYKKQNKGEVPTPRYVVVNSQGKAEAEVKVEVALHKTEGTFYDYRRVADGKRAEVDDAYRA

The query sequence (length=556) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6ju4:B 560 559 0.9946 0.9875 0.9893 0.0 6ju4:A, 6ju5:A, 6ju5:B, 6jua:B, 6jub:B, 6juc:A, 6juc:B, 6jud:B, 3w6w:B
2 3w6w:A 583 583 0.9964 0.9503 0.9503 0.0 6ju7:A, 6ju7:B, 6ju8:A, 6ju8:B, 6ju9:A, 6ju9:B
3 6jua:A 533 567 0.9371 0.9775 0.9189 0.0 6jub:A, 6jud:A
4 2y9w:A 391 429 0.2194 0.3120 0.2844 3.70e-41 2y9w:B, 2y9x:A, 2y9x:B, 2y9x:C, 2y9x:D
5 4oua:B 557 517 0.2572 0.2567 0.2766 1.06e-34 5m6b:B, 5m6b:A, 5m6b:D, 4oua:A
6 5m6b:C 514 538 0.2644 0.2860 0.2732 1.42e-29
7 5zrd:A 534 358 0.1745 0.1816 0.2709 2.06e-15 5zrd:B, 5zrd:C, 5zrd:D
8 5zre:B 474 355 0.1583 0.1857 0.2479 5.71e-12 5zre:A, 5zre:C
9 4yd9:A 1656 120 0.0701 0.0236 0.3250 4.04e-10 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
10 4yd9:A 1656 64 0.0468 0.0157 0.4062 2.62e-07 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
11 4yd9:A 1656 61 0.0432 0.0145 0.3934 1.69e-05 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
12 4yd9:A 1656 65 0.0450 0.0151 0.3846 3.34e-05 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
13 4yd9:A 1656 123 0.0540 0.0181 0.2439 0.012 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
14 4yd9:A 1656 172 0.0647 0.0217 0.2093 0.29 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
15 4yd9:A 1656 198 0.0809 0.0272 0.2273 1.2 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
16 4yd9:A 1656 61 0.0324 0.0109 0.2951 7.8 4yd9:D, 4yd9:G, 4yd9:J, 4yd9:M, 4yd9:P, 4yd9:S, 4yd9:V, 4yd9:Y, 4yd9:b
17 8tnv:A 393 113 0.0629 0.0891 0.3097 4.55e-09 8tnv:B
18 8tnv:A 393 155 0.0737 0.1043 0.2645 1.0 8tnv:B
19 4bed:B 1734 118 0.0647 0.0208 0.3051 4.72e-09 4bed:D, 3qjo:A, 3qjo:B
20 4bed:B 1734 332 0.1403 0.0450 0.2349 8.25e-09 4bed:D, 3qjo:A, 3qjo:B
21 4bed:B 1734 90 0.0504 0.0161 0.3111 2.52e-06 4bed:D, 3qjo:A, 3qjo:B
22 4bed:B 1734 88 0.0468 0.0150 0.2955 0.003 4bed:D, 3qjo:A, 3qjo:B
23 4bed:B 1734 46 0.0288 0.0092 0.3478 0.005 4bed:D, 3qjo:A, 3qjo:B
24 4yd9:B 825 117 0.0665 0.0448 0.3162 8.04e-08 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c
25 4yd9:B 825 65 0.0432 0.0291 0.3692 6.12e-07 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c
26 4yd9:B 825 92 0.0396 0.0267 0.2391 0.52 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c
27 8hpi:A 289 131 0.0683 0.1315 0.2901 8.33e-08 4d87:A, 4d87:B, 6ei4:A, 6ei4:B, 4hd4:A, 4hd4:B, 4hd6:A, 4hd6:B, 4hd7:A, 4hd7:B, 8hpi:B, 5i38:A, 5i38:B, 5i3a:A, 5i3a:B, 5i3b:A, 5i3b:B, 4j6t:A, 4j6t:B, 4j6v:A, 4j6v:B, 3nm8:A, 3nm8:B, 3npy:A, 3npy:B, 3nq0:A, 3nq0:B, 3nq1:A, 3nq1:B, 3nq5:A, 3nq5:B, 3ntm:A, 3ntm:B, 5oae:A, 5oae:B, 4p6r:A, 4p6r:B, 4p6s:A, 4p6s:B, 4p6t:A, 4p6t:B, 6qxd:A, 6qxd:B
28 4yd9:L 366 119 0.0665 0.1011 0.3109 3.64e-07 4yd9:C, 4yd9:a, 4yd9:F, 4yd9:R, 4yd9:I, 4yd9:O, 4yd9:U, 4yd9:X, 4yd9:d
29 4yd9:L 366 107 0.0594 0.0902 0.3084 0.30 4yd9:C, 4yd9:a, 4yd9:F, 4yd9:R, 4yd9:I, 4yd9:O, 4yd9:U, 4yd9:X, 4yd9:d
30 1js8:A 382 120 0.0647 0.0942 0.3000 9.26e-07 1js8:B
31 1js8:A 382 91 0.0396 0.0576 0.2418 6.5 1js8:B
32 4bed:A 1664 64 0.0468 0.0156 0.4062 1.30e-06 4bed:C
33 4bed:A 1664 65 0.0450 0.0150 0.3846 3.16e-06 4bed:C
34 4bed:A 1664 64 0.0432 0.0144 0.3750 1.37e-05 4bed:C
35 4bed:A 1664 89 0.0576 0.0192 0.3596 3.34e-05 4bed:C
36 4bed:A 1664 92 0.0486 0.0162 0.2935 5.98e-04 4bed:C
37 4bed:A 1664 119 0.0522 0.0174 0.2437 0.49 4bed:C
38 1lnl:A 408 64 0.0450 0.0613 0.3906 1.50e-06 1lnl:B, 1lnl:C
39 1lnl:A 408 114 0.0540 0.0735 0.2632 2.4 1lnl:B, 1lnl:C
40 6j2u:B 273 63 0.0468 0.0952 0.4127 5.15e-06
41 5ce9:A 339 104 0.0540 0.0885 0.2885 1.46e-04 5ce9:B
42 5z0f:A 279 57 0.0396 0.0789 0.3860 2.28e-04 2ahk:A, 2ahl:A, 3aws:A, 3awt:A, 3awu:A, 3awv:A, 3aww:A, 3awx:A, 3awy:A, 3awz:A, 3ax0:A, 7cit:A, 7ciy:A, 1wx2:A, 1wx4:A, 5z0d:A, 5z0e:A, 5z0g:A, 5z0h:A, 5z0i:A, 5z0j:A, 5z0k:A, 5z0l:A, 5z0m:A, 2zmx:A, 2zmy:A, 2zmz:A, 2zwd:A, 2zwe:A, 2zwf:A, 2zwg:A
43 4z11:A 513 114 0.0576 0.0624 0.2807 2.56e-04 4z0y:A, 4z0y:B, 4z0y:D, 4z0y:C, 4z0z:A, 4z0z:B, 4z0z:C, 4z0z:D, 4z10:A, 4z10:C, 4z10:B, 4z10:D, 4z10:E, 4z10:F, 4z11:B, 4z11:C, 4z11:D, 4z12:A, 4z12:B, 4z13:A, 4z13:B, 4z14:D, 4z14:B, 4z14:H, 4z14:F, 4z14:C, 4z14:E, 4z14:G, 4z14:A
44 4z11:A 513 82 0.0414 0.0448 0.2805 0.83 4z0y:A, 4z0y:B, 4z0y:D, 4z0y:C, 4z0z:A, 4z0z:B, 4z0z:C, 4z0z:D, 4z10:A, 4z10:C, 4z10:B, 4z10:D, 4z10:E, 4z10:F, 4z11:B, 4z11:C, 4z11:D, 4z12:A, 4z12:B, 4z13:A, 4z13:B, 4z14:D, 4z14:B, 4z14:H, 4z14:F, 4z14:C, 4z14:E, 4z14:G, 4z14:A
45 8bbq:A 324 55 0.0414 0.0710 0.4182 5.78e-04 8bbq:B, 8bbr:A, 8bbr:B
46 6hqi:A 444 113 0.0558 0.0698 0.2743 0.003
47 6els:A 459 108 0.0540 0.0654 0.2778 0.007 6elt:A, 6elv:A
48 6els:A 459 80 0.0342 0.0414 0.2375 4.6 6elt:A, 6elv:A
49 6z1s:A 381 63 0.0342 0.0499 0.3016 0.048
50 4j3r:A 372 55 0.0378 0.0565 0.3818 0.051 6gsg:A, 4j3p:A, 4j3q:A, 4j3q:B, 5or3:A, 5or3:B, 5or3:C, 5or3:D, 5or4:A, 5or4:B, 5or4:C, 5or4:D
51 1bug:A 336 111 0.0522 0.0863 0.2613 0.26 1bug:B
52 1bug:A 336 82 0.0342 0.0565 0.2317 2.4 1bug:B
53 6kxf:A 403 82 0.0306 0.0422 0.2073 1.3
54 2r1b:A 198 51 0.0306 0.0859 0.3333 1.6 2r1b:B
55 8ova:Br 367 79 0.0432 0.0654 0.3038 3.3 8ove:Br, 4v8m:Br
56 9etk:A 280 33 0.0198 0.0393 0.3333 4.5
57 1odt:C 317 44 0.0216 0.0379 0.2727 7.5 1odt:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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