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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVKSVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCL
AIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEKELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDV
PADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMCTSGFTVVVKESCDGMGDVSEKPEKAVRFSFTIMSISIRLE
GEDDGITIFQEQKPNSELSCRPLCLMFVDESDHETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGTGYDEKMV
REMEGLEASGSTYICTLCDSTRAEASQNMVLHSITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFMETQPTLD
ALHCDIGNATEFYKIFQDEIGEVYQKPNPSREERRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEAVCELVPS
EERREALLKLMDLYLQMKPVWRSTCPSRDCPDQLCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPEIVERDGS
IGAWASEGNESGNKLFRRFRKMNARQSKTFELEDILKHHWLYTSKYLQKFMEAH

The query sequence (length=614) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6dbi:C 622 621 1.0000 0.9871 0.9887 0.0 6dbi:A, 6dbj:A, 6dbj:C, 6dbl:A, 6dbl:C, 6dbo:A, 6dbo:C, 6dbq:A, 6dbq:C, 6dbr:A, 6dbr:C, 6dbt:A, 6dbt:C, 6dbu:A, 6dbu:C, 6dbv:A, 6dbv:C, 6dbw:A, 6dbw:C, 6dbx:A, 6dbx:C, 3jbw:A, 3jbw:C, 3jbx:A, 3jbx:C, 3jby:A, 3jby:C
2 6oet:C 623 621 0.7736 0.7624 0.7649 0.0 6cg0:A, 6cg0:C, 6cij:A, 6cij:C, 6cik:A, 6cik:C, 6cil:A, 6cil:C, 6cim:A, 6cim:C, 3gna:A, 3gnb:A, 6oem:A, 6oem:C, 6oen:A, 6oen:C, 6oeo:A, 6oeo:C, 6oep:A, 6oep:C, 6oeq:A, 6oeq:C, 6oer:A, 6oer:C, 6oes:A, 6oes:C, 6oet:A, 6v0v:A, 4wwx:B, 4wwx:E, 6xnx:A, 6xnx:C, 6xny:A, 6xny:C, 6xnz:A, 6xnz:C, 5zdz:A, 5zdz:C, 5ze0:A, 5ze0:C, 5ze1:A, 5ze1:C, 5ze2:A, 5ze2:C
3 6b40:A 553 552 0.2980 0.3309 0.3315 1.74e-82 6b40:E
4 6pqx:A 480 60 0.0358 0.0458 0.3667 0.022 6pqx:E, 6pr5:A, 6pr5:E
5 6pqx:A 480 100 0.0456 0.0583 0.2800 3.0 6pqx:E, 6pr5:A, 6pr5:E
6 6pqr:A 468 60 0.0358 0.0470 0.3667 0.023 6pqn:A, 6pqn:B, 6pqr:D, 6pqu:A, 6pqu:E, 6pqy:A, 6pqy:D
7 6pqr:A 468 166 0.0635 0.0833 0.2349 2.9 6pqn:A, 6pqn:B, 6pqr:D, 6pqu:A, 6pqu:E, 6pqy:A, 6pqy:D
8 7wtl:CL 610 140 0.0521 0.0525 0.2286 2.2 5wyj:B1, 5wyk:B1
9 7aju:CL 808 63 0.0293 0.0223 0.2857 2.6 6zqd:CL, 6zqe:CL, 6zqf:CL, 6zqg:CL
10 7suk:SI 802 63 0.0293 0.0224 0.2857 2.7 7d63:RJ, 6ke6:RJ, 6lqp:RJ, 6lqq:RJ, 6lqr:RJ, 6lqu:RJ, 6lqv:RJ, 5wlc:SI
11 7ajt:CL 781 63 0.0293 0.0230 0.2857 2.8 7d5s:RJ, 6zqa:CL, 6zqb:CL, 6zqc:CL
12 7d4i:RJ 738 63 0.0293 0.0244 0.2857 3.1 7d5t:RJ, 6lqs:RJ, 6lqt:RJ
13 6os6:A 362 73 0.0342 0.0580 0.2877 3.8 6os5:A, 6os5:B, 6os5:C
14 7bkb:B 296 37 0.0244 0.0507 0.4054 4.5 7bkb:b, 7bkc:B, 7bkc:b, 7bkd:B, 7bkd:b, 7bke:B, 7bke:b
15 3glj:A 395 55 0.0244 0.0380 0.2727 5.5 5j1q:A, 5jc6:A, 2jew:A, 5lrg:A, 5lrg:B, 5lrg:C, 5lrj:A, 5lrj:B, 5lrj:C, 5lrk:A, 5lrk:B, 5lrk:C, 5lyd:A, 5lyf:A, 5lyi:A, 5lyl:A, 1nsa:A, 2piy:A, 2piy:B, 2piy:C, 2piz:A, 2piz:B, 2piz:C, 2pj0:A, 2pj0:B, 2pj0:C, 2pj1:A, 2pj1:B, 2pj1:C, 2pj2:A, 2pj2:B, 2pj2:C, 2pj3:A, 2pj3:B, 2pj3:C, 2pj4:A, 2pj4:B, 2pj5:A, 2pj5:B, 2pj5:C, 2pj6:A, 2pj7:A, 2pj7:B, 2pj7:C, 2pj8:A, 2pj8:B, 2pj8:C, 2pj9:A, 2pja:A, 2pja:B, 2pja:C, 2pjb:A, 2pjb:B, 2pjb:C, 2pjc:A, 2pjc:B, 2pjc:C, 4uia:A, 4uib:A, 3wab:A, 3wc5:A, 3wc6:A, 3wc7:A, 1z5r:A, 1z5r:B, 1z5r:C, 4z65:A, 5zeq:A, 1zg7:A, 1zg7:B, 1zg7:C, 1zg8:A, 1zg8:B, 1zg8:C, 1zg9:A, 1zg9:B, 1zg9:C
16 2yt5:A 66 24 0.0163 0.1515 0.4167 5.9
17 7umz:A 3927 56 0.0261 0.0041 0.2857 8.6 6g4s:s, 6g4w:s, 5j4z:G, 5j7y:G, 5j8k:G, 5tzs:Q, 7umz:D, 7umz:B, 7umz:C, 5wyj:UC, 5wyj:AG, 5wyk:AG, 5wyk:UC, 4wz7:A, 6xyw:AP
18 6x33:B 3816 56 0.0261 0.0042 0.2857 9.4 8drp:A, 8drp:B, 8drp:C, 8drp:D, 6x33:E, 6x33:H, 6x33:K
19 7k0s:A 4110 56 0.0261 0.0039 0.2857 9.6 7k0s:B, 7k0s:D, 7k0s:C, 7k0t:A, 7k0t:B, 7k0t:D, 7k0t:C
20 6x35:B 3801 56 0.0261 0.0042 0.2857 9.7 6x35:E, 6x35:H, 6x35:K
21 8dve:G 3944 56 0.0261 0.0041 0.2857 9.8 8dtb:A, 8dve:D, 8dve:A, 8dve:J
22 6x32:B 3798 56 0.0261 0.0042 0.2857 9.9 6x32:E, 6x32:H, 6x32:K

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218