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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GFLVAAIQFPVPIVNSRKDIDHNIESIIRTLHATKAGYPGVELIIFPEYSTQGLNTAKWLSEEFLLDVPGKETELYAKAC
KEAKVYGVFSIMERNPDSNKNPYNTAIIIDPQGEIILKYRKLFPWNPIEPWYPGDLGMPVCEGPGGSKLAVCISHDGMIP
ELAREAAYKGCNVYIRISGYSTQVNDQWILTNRSNAWHNLMYTVSVNLAGYYFGEGQICNFDGTTLVQGHRNPWEIVTGE
IYPKMADNARLSWGLENNIYNLGHRGYVAKPGGEHDAGLTYIKDLAAGKYKLPWEDHMKIKDGSIYGYPTTGGRFGK

The query sequence (length=317) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2e2l:A 317 317 1.0000 1.0000 1.0000 0.0 2e2l:C, 2e2l:F
2 4gyl:A 340 284 0.3186 0.2971 0.3556 1.97e-54 4gyn:A, 4kzf:A
3 6ypa:B 269 229 0.2019 0.2379 0.2795 1.14e-10 7ovg:A, 7ovg:B, 6ypa:A, 6ypa:C, 6ypa:D
4 3klc:A 261 226 0.1924 0.2337 0.2699 8.40e-10 3klc:B
5 8hpc:C 303 304 0.2334 0.2442 0.2434 3.03e-08 8hpc:A, 8hpc:B, 8hpc:D, 8hpc:E, 8hpc:F, 8hpc:G, 8hpc:H, 1uf5:A, 1uf5:B, 1uf7:A, 1uf7:B, 1uf8:A, 1uf8:B
6 5h8i:C 301 205 0.1735 0.1827 0.2683 5.44e-06 5h8i:B, 5h8i:D, 5h8i:E, 5h8i:F, 5h8i:G, 5h8i:J, 5h8i:K, 5h8i:L, 5h8i:M, 5h8i:N, 5h8i:O, 5h8j:B, 5h8j:C, 5h8j:D, 5h8j:E, 5h8j:F, 5h8j:G, 5h8j:J, 5h8j:K, 5h8j:L, 5h8j:M, 5h8j:N, 5h8j:O, 5h8l:B, 5h8l:C, 5h8l:D, 5h8l:E, 5h8l:F, 5h8l:G, 5h8l:J, 5h8l:K, 5h8l:L, 5h8l:M, 5h8l:N, 5h8l:O
7 4izt:A 263 159 0.1230 0.1483 0.2453 1.10e-04 4izs:A, 4izu:A, 4izv:A, 4izw:A, 5ny7:A, 5nyb:A, 5nyc:A, 5nye:A
8 8uxu:A 317 136 0.1104 0.1104 0.2574 0.003 8uxu:B, 8uxu:C, 8uxu:D, 8uxu:E, 8uxu:F, 8uxu:G, 8uxu:H, 8uxu:I, 8uxu:J, 8uxu:K, 8uxu:L, 8uxu:M, 8uxu:N
9 5k61:A 431 98 0.0820 0.0603 0.2653 0.008 5b62:A, 5k60:A, 5k62:A, 5k63:A, 5k66:A
10 4cyg:A 463 114 0.0852 0.0583 0.2368 0.095 4cyg:B, 7slv:A, 7slx:A, 7sly:A
11 5kha:A 526 111 0.0978 0.0589 0.2793 0.10 5kha:B
12 4hg3:A 304 125 0.0978 0.1020 0.2480 0.31 4hg3:B, 4hg3:C, 4hg3:D, 4hg5:A, 4hg5:B, 4hg5:C, 4hg5:D, 4hgd:A, 4hgd:B, 4hgd:C, 4hgd:D
13 5epe:A 248 73 0.0694 0.0887 0.3014 1.5
14 2wop:A 554 49 0.0442 0.0253 0.2857 2.5 2wok:A
15 3wrg:A 658 53 0.0536 0.0258 0.3208 3.6 7bzl:A, 7dif:A, 7exu:A, 7exv:A, 7exw:A, 8qf2:A, 3wkx:A, 3wre:A
16 7f5m:A 139 56 0.0568 0.1295 0.3214 6.2 7f5m:B
17 1v33:A 346 78 0.0568 0.0520 0.2308 6.9 1v34:A
18 5ceo:A 269 29 0.0379 0.0446 0.4138 8.0 5cep:A, 5ceq:A, 8deg:A, 8our:A, 8ous:A, 8out:A, 5vo1:A, 5vo2:A
19 2r6f:B 879 88 0.0757 0.0273 0.2727 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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