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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFAS
GLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDI
EGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSP
IDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFL
KNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPS

The query sequence (length=392) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3cog:D 392 392 1.0000 1.0000 1.0000 0.0 3cog:A, 3cog:B, 3cog:C, 5eig:C, 5eig:D, 5eig:E, 5eig:F, 5eig:G, 6nba:A, 6nba:B, 6nba:C, 6nba:D, 2nmp:A, 2nmp:B, 2nmp:C, 2nmp:D, 5tsu:A, 5tsu:C, 5tsu:D, 5tsu:E, 5tsu:F, 5tsu:G, 5tsu:H
2 8j6n:A 390 390 0.8546 0.8590 0.8590 0.0 8j6n:D, 8j6n:B, 8j6n:C, 8j6n:E, 8j6n:H, 8j6n:J, 8j6n:K, 8j6n:F, 8j6n:G, 8j6n:I, 8j6n:L
3 4iyo:D 384 380 0.5306 0.5417 0.5474 1.48e-139 4ixs:B, 4ixz:A, 4iy7:A, 4iy7:B, 4iy7:C, 4iy7:D, 4iyo:A, 4iyo:B, 4iyo:C
4 6k1l:A 382 381 0.5306 0.5445 0.5459 9.69e-136 6k1l:B, 6k1l:C, 6k1l:D, 6k1m:A, 6k1m:B, 6k1m:C, 6k1m:D, 6k1n:A, 6k1n:B, 6k1n:C, 6k1n:D
5 1n8p:A 393 387 0.5102 0.5089 0.5168 2.25e-132 1n8p:B, 1n8p:C, 1n8p:D
6 4l0o:H 373 375 0.4796 0.5040 0.5013 4.12e-127 4l0o:A, 4l0o:C, 4l0o:E, 4l0o:G, 4l0o:M, 4l0o:O
7 6cja:A 381 380 0.5077 0.5223 0.5237 1.02e-126 6cja:B, 6cja:C, 6cja:D
8 7ba4:A 377 385 0.4974 0.5172 0.5065 1.30e-126 7ba4:B, 7ba4:C, 7ba4:D
9 7d7o:B 377 362 0.4515 0.4695 0.4890 1.88e-122 7d7o:A
10 5x5h:A 385 390 0.4643 0.4727 0.4667 2.73e-116
11 7mcb:H 380 376 0.4362 0.4500 0.4548 3.56e-113 7mcl:H, 7mcn:H, 7mcp:A, 7mcp:H, 7mcq:A, 7mcq:H, 7mct:H, 7mcu:H, 7mcy:H, 7md0:H, 7md6:H, 7md8:H, 7mda:H, 7mdb:H
12 6ldo:A 381 379 0.4184 0.4304 0.4327 3.65e-109 6ldo:B, 6ldo:C, 6ldo:D, 6ldo:E, 6ldo:F, 6le4:A, 6le4:B, 6le4:C, 6le4:D, 6le4:E, 6le4:F
13 1ibj:A 380 360 0.4031 0.4158 0.4389 9.49e-109 1ibj:C
14 1pg8:A 398 391 0.4515 0.4447 0.4527 2.69e-108 7f1u:A, 7f1u:B, 7f1u:C, 7f1u:D, 7f1v:A, 7f1v:B, 7f1v:C, 7f1v:D, 1pg8:C, 1pg8:B, 1pg8:D, 3vk3:A, 3vk3:B, 3vk3:C, 3vk3:D, 5x2w:A, 5x2w:B, 5x2w:C, 5x2w:D, 5x2x:A, 5x2x:B, 5x2x:C, 5x2x:D, 5x2z:A, 5x2z:B, 5x2z:C, 5x2z:D, 5x30:A, 5x30:B, 5x30:C, 5x30:D
15 3qhx:A 377 379 0.4541 0.4721 0.4697 1.48e-107 3qhx:B
16 6egr:A 396 391 0.4464 0.4419 0.4476 3.61e-107 5d5s:A, 5e4z:A, 4hf8:A, 3jw9:A, 3jwa:A, 3jwb:A, 5k30:A, 5m3z:A, 3mkj:A, 4oma:A, 6s0c:A
17 5dx5:A 399 390 0.4337 0.4261 0.4359 9.76e-104 5dx5:B
18 1e5e:A 394 388 0.4107 0.4086 0.4149 1.08e-99 1e5e:B, 1e5f:A, 1e5f:B
19 8jui:A 380 362 0.4056 0.4184 0.4392 1.81e-98
20 1cs1:D 384 382 0.4056 0.4141 0.4162 1.11e-94
21 6ld8:A 388 381 0.3980 0.4021 0.4094 1.94e-90 6ld8:D, 6ld8:B, 6ld8:C, 6ld9:A, 6ld9:B, 6ld9:C, 6ld9:D, 6lgo:A, 6lgo:B, 6lgo:C, 6lgo:D
22 3aej:A 387 365 0.3878 0.3928 0.4164 2.38e-89 3aej:D, 3aej:B, 3aej:C, 3ael:A, 3ael:D, 3ael:B, 3ael:C, 3aem:A, 3aem:D, 3aem:B, 3aem:C, 3aen:A, 3aen:D, 3aen:B, 3aen:C, 3aeo:A, 3aeo:D, 3aeo:B, 3aeo:C, 3aep:A, 3aep:D, 3aep:B, 3aep:C
23 7nl1:D 400 393 0.4005 0.3925 0.3995 5.89e-86 8bis:C, 8bis:A, 8biu:G, 8biu:A, 8biv:A, 8biv:E, 8biw:E, 8biw:A, 8bix:C, 8bix:A, 8biz:E, 8biz:A, 7nl1:A, 7nl1:B, 7nl1:C, 7nl1:E, 7nl1:F, 7nl1:G, 7nl1:H
24 1qgn:A 398 345 0.3393 0.3342 0.3855 7.27e-78 1i41:A, 1i41:C, 1i41:B, 1i41:D, 1i41:E, 1i41:G, 1i41:F, 1i41:H, 1i41:I, 1i41:K, 1i41:J, 1i41:L, 1i43:A, 1i43:C, 1i43:B, 1i43:D, 1i43:E, 1i43:G, 1i43:F, 1i43:H, 1i43:I, 1i43:K, 1i43:J, 1i43:L, 1i48:A, 1i48:C, 1i48:B, 1i48:D, 1i48:E, 1i48:G, 1i48:F, 1i48:H, 1i48:I, 1i48:K, 1i48:J, 1i48:L, 1qgn:C, 1qgn:B, 1qgn:D, 1qgn:E, 1qgn:G, 1qgn:F, 1qgn:H
25 7kb1:A 428 424 0.3878 0.3551 0.3585 5.03e-67 7kb1:B, 7kb1:C, 7kb1:D
26 5ijg:B 403 410 0.3520 0.3424 0.3366 1.30e-62 5ijg:A
27 8erb:K 429 427 0.3597 0.3287 0.3302 5.51e-62 8erb:A, 8erb:C, 8erb:B, 8erb:D, 8erb:G, 8erb:H, 8erb:F, 8erb:P, 8erb:I, 8erb:J, 8erb:M, 8erb:E, 8erb:Q, 8erb:N, 8erb:L, 8erj:A, 8erj:B, 8erj:C, 8erj:D, 8erj:E, 8erj:F, 8erj:H, 8erj:G
28 8wko:A 425 423 0.3444 0.3176 0.3191 1.66e-61 8wko:B, 8wkr:A, 8wkr:B, 8wkr:C, 8wkr:D
29 2ctz:A 421 422 0.3597 0.3349 0.3341 4.33e-60 2ctz:B
30 1cl1:B 392 338 0.2832 0.2832 0.3284 4.64e-53 1cl1:A, 1cl2:A, 1cl2:B, 2fq6:A, 2fq6:B, 2gqn:A, 2gqn:B, 4itx:A, 4itx:B
31 8sad:A 398 339 0.2806 0.2764 0.3245 1.25e-50 8sa7:A, 8sa7:B, 8sa8:A, 8sa8:D, 8sa8:B, 8sa8:C, 8sa9:A, 8sa9:B, 8saa:A, 8saa:B, 8sab:A, 8sab:B, 8sac:A, 8sac:D, 8sac:B, 8sac:C, 8sad:B, 8sae:A, 8sae:B, 8u98:A, 8u98:D, 8u98:B, 8u98:C, 8u99:A, 8u99:B
32 2cb1:A 404 362 0.3010 0.2921 0.3260 6.54e-46
33 8ovh:A 400 427 0.3418 0.3350 0.3138 4.82e-45 8ovh:B, 8ovh:C, 8ovh:D
34 7yeo:B 382 384 0.3010 0.3089 0.3073 3.96e-34 7yeo:A
35 1v2e:A 368 124 0.0867 0.0924 0.2742 3.33e-05 1v2d:A, 1v2e:B, 1v2f:A, 1v2f:B
36 8wkj:A 391 83 0.0612 0.0614 0.2892 0.001
37 3nu7:B 359 135 0.1020 0.1114 0.2963 0.003 3nu7:A, 3nub:A, 3nub:B, 3nys:A, 3nyt:A
38 8e77:A 358 97 0.0765 0.0838 0.3093 0.007
39 4m2j:A 382 114 0.0714 0.0733 0.2456 0.009 4m2k:A, 4m2m:A
40 6f35:A 400 51 0.0434 0.0425 0.3333 0.054 6f35:B
41 2r5c:B 419 113 0.0842 0.0788 0.2920 0.22 2r5e:A, 2r5e:B, 1yiy:A, 1yiy:B
42 2f5q:A 273 41 0.0459 0.0659 0.4390 0.23 2f5p:A, 2f5s:A, 4g4q:A, 3gpy:A, 3gq4:A, 3jr4:A, 3jr5:A, 1l1t:A, 1l1z:A, 1l2b:A, 1l2c:A, 1l2d:A, 1r2y:A, 1r2z:A
43 3if2:A 437 38 0.0408 0.0366 0.4211 0.28 3if2:B
44 3jtx:B 393 83 0.0561 0.0560 0.2651 0.43
45 6f77:A 399 88 0.0587 0.0576 0.2614 0.60 6f77:C, 6f77:D, 6f77:E, 6f77:F
46 1u08:A 382 177 0.1020 0.1047 0.2260 0.78 1u08:B
47 4r2n:A 353 85 0.0536 0.0595 0.2471 0.95 4r2n:C, 4r2n:B, 4r2n:D, 4r5z:A, 4r5z:B, 4r5z:C, 4r5z:D
48 1b5o:A 382 48 0.0459 0.0471 0.3750 1.1 1b5o:B, 1b5p:A, 1b5p:B, 1bjw:A, 1bjw:B, 5bj3:A, 5bj3:B, 5bj3:C, 5bj3:D, 5bj4:A, 5bj4:B, 1bkg:A, 1bkg:B, 1bkg:C, 1bkg:D, 1gc3:A, 1gc3:B, 1gc3:C, 1gc3:D, 1gc3:E, 1gc3:F, 1gc3:G, 1gc3:H, 1gc4:A, 1gc4:B, 1gc4:C, 1gc4:D, 1gck:A, 1gck:B
49 1j32:A 388 45 0.0408 0.0412 0.3556 2.6 1j32:B
50 4njm:A 303 50 0.0357 0.0462 0.2800 2.9 4njm:B, 4njo:A
51 8bob:A 390 68 0.0561 0.0564 0.3235 3.5 8bob:B, 1d2f:A, 1d2f:B
52 4g4n:A 253 30 0.0332 0.0514 0.4333 3.6 2f5n:A, 2f5o:A, 4g4o:A, 4g4r:A, 3go8:A, 3gp1:A, 3gpp:A, 3gpu:A, 3gpx:A, 3gq3:A, 3gq5:A, 3sar:A, 3sas:A, 3sat:A, 3sau:A, 3sav:A, 3saw:A, 3sbj:A, 3u6c:A, 3u6d:A, 3u6e:A, 3u6l:A, 3u6m:A, 3u6o:A, 3u6p:A, 3u6q:A, 3u6s:A
53 3v1h:A 306 100 0.0587 0.0752 0.2300 5.0 4f2b:A, 4f2b:B, 4i90:A, 4i9j:A, 4i9t:A, 4rv3:A, 4s3g:A, 3v16:A
54 2x5d:D 380 182 0.0867 0.0895 0.1868 7.7 2x5d:A
55 3fvs:B 419 92 0.0561 0.0525 0.2391 7.8 3fvu:A, 3fvu:B, 1w7l:A, 1w7m:A, 1w7n:A, 4wlj:A, 4wlj:B
56 8k3h:A 480 31 0.0281 0.0229 0.3548 8.0 8k3h:B
57 5w70:A 414 186 0.1148 0.1087 0.2419 8.3 5w70:B
58 4cvq:A 404 59 0.0485 0.0470 0.3220 8.8 4cvq:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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