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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GEGMWVPQQLPEIAGPLKKAGLKLSPQQISDLTGDPMGAVVALGGCTASFVSPNGLVVTNHACAYGAIQLNSTAENNLIK
NGFNAPTTADEVSAGPNARVFVLDEITDVTKDAKAAIAAAGDDALARTKALEAFEKKLIADCEAEAGFRCRLYSFSGGNT
YRLFKNLEIKDVRLAYAPPGSVGKFGGDIDNWMWPRHTGDFAFYRAYVGKDGKPAAFSKDNVPYQPKHWLKFADQPLGAG
DFVMVAGYPGSTNRYALAAEFDNTAQWTYPTIARHYKNQIAMVEAAGKQNADIQVKYAATMAGWNNTSKNYDGQLEGFKR
IDAAGQKLREEAAVLGWLKGQGAKGQPALDAHAKLLDLLEQSKATRDRDLTLALFNNTAMLGSATQLYRLSIEREKPNAE
RESGYQERDLPAIEGGLKQLERRYVAAMDRQLQEYWLNEYIKLPADQRVAAVDAWLGGNDAAAVKRALDRLAGTKLGSTE
ERLKWFAADRKAFEASNDPAIQYAVAVMPTLLKLEQERKTRAGENLAARPVYLQALADYKKSQGEFVYPDANLSLRITFG
NVMGYAPKDGMEYTPFTTLEGVVAKETGQDPFDSPKALLDAVAAKRYGGLEDKRIGSVPVNYLSDLDITGGNSGSPVLDA
HGKLVGLAFDGNWESVSSNWVFDPKMTRMIAVDGRYLRWIMQEVYPAPQLLKEMNVG

The query sequence (length=697) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3woj:A 698 697 0.9986 0.9971 0.9986 0.0 3woi:B, 3woj:B, 3wol:A, 3wol:B, 3wom:A, 3wom:B, 3won:A, 3won:B, 3woo:A, 3woo:B, 3wop:A, 3wop:B, 3woq:A, 3woq:B, 3wor:A, 3wor:B, 4y06:A, 4y06:B
2 7dkb:A 697 696 0.7834 0.7834 0.7845 0.0 7dkb:B, 7dkc:A, 7dkc:B, 7dkd:A, 7dkd:B, 7dke:A, 7dke:B, 8grt:A, 8grt:B
3 5jwg:A 703 726 0.3271 0.3243 0.3140 4.20e-101 5jwg:B, 5jwi:A, 5jwi:B, 5jy0:A
4 6jtc:A 699 722 0.3372 0.3362 0.3255 1.40e-99 6jtc:B, 7r51:A, 7r51:B, 5sdc:A, 5sdc:B, 5sdd:A, 5sdd:B, 5sde:A, 5sde:B, 5sdf:A, 5sdf:B, 5sdg:A, 5sdg:B, 5sdh:A, 5sdh:B, 5sdi:A, 5sdi:B, 5sdj:A, 5sdk:A, 5sdl:A, 5sdl:B, 5sdm:A, 5sdm:B, 5sdn:A, 5sdn:B, 5sdo:A, 5sdo:B, 5sdp:A, 5sdp:B, 5sdq:A, 5sdq:B, 5sdr:A, 5sdr:B
5 5jxp:A 662 716 0.3156 0.3323 0.3073 7.39e-98
6 5jxf:A 694 706 0.3156 0.3170 0.3116 7.95e-95 5jxf:B
7 7r81:s1 149 97 0.0430 0.2013 0.3093 0.21
8 4k1t:C 203 42 0.0244 0.0837 0.4048 0.40 4k1t:A, 4k1t:B
9 1wcz:A 215 27 0.0187 0.0605 0.4815 0.58
10 2m9p:A 240 26 0.0201 0.0583 0.5385 0.67 2m9q:A
11 7m1v:A 166 41 0.0230 0.0964 0.3902 0.80
12 4ic5:A 210 24 0.0158 0.0524 0.4583 0.93 4ic5:B, 4ic5:C
13 6mo0:A 164 22 0.0187 0.0793 0.5909 1.2 6mo0:B, 6mo1:A, 6mo1:B, 6mo2:A, 6mo2:B
14 2as9:A 207 39 0.0230 0.0773 0.4103 1.2 2as9:B
15 4r8t:B 141 26 0.0187 0.0922 0.5000 2.9
16 8jej:A 540 53 0.0230 0.0296 0.3019 2.9 8jek:A, 8k6j:A, 8k6k:A, 7w2j:A, 7w2j:D, 7wsq:A, 7wsq:D, 8xcm:A, 8xcn:A
17 5lc0:A 193 41 0.0230 0.0829 0.3902 3.2 8a15:B, 8aqa:A, 8aqa:B, 8aqb:A, 8aqb:B, 8aqk:A, 8aqk:B, 7doc:A, 7doc:B, 7h1h:B, 7h1i:B, 7h1j:B, 7h1k:B, 7h1l:B, 7h1m:B, 7h1n:B, 7h1o:B, 7h1p:A, 7h1p:B, 7h1q:B, 7h1r:B, 7h1s:B, 7h1t:B, 7h1u:B, 7h1v:B, 7h1w:B, 7h1x:B, 7h1y:B, 7h1z:B, 7h20:B, 7h21:B, 7h22:A, 7h22:B, 7h23:B, 7h24:B, 7h25:B, 7h27:B, 7h28:B, 7h29:B, 7h2a:B, 7h2b:B, 7h2c:B, 7h2c:A, 7h2d:B, 7h2e:B, 7h2f:B, 7h2g:B, 7h2h:B, 7h2i:B, 7h2j:B, 7h2k:B, 7h2l:B, 7h2m:B, 7h2n:B, 7h2o:B, 7h2p:A, 7h2p:B, 7h2q:B, 7h2r:B, 7h2s:B, 5h4i:B, 5h6v:A, 5h6v:B, 6jpw:C, 6jpw:D, 6jpw:E, 6jpw:F, 6jpw:G, 6jpw:H, 6kk2:A, 6kk2:B, 6kk3:A, 6kk3:B, 6kk4:A, 6kk4:B, 6kk5:A, 6kk5:B, 6kk6:A, 6kk6:B, 6kpq:B, 6l4z:H, 6l50:H, 5lc0:B, 7o2m:A, 7o2m:B, 7o55:A, 7o55:B, 7obv:A, 7obv:B, 7oc2:A, 7oc2:B, 7pfq:A, 7pfq:B, 7pfy:A, 7pfy:B, 7pfz:A, 7pfz:B, 7pg1:A, 7pg1:B, 7pgc:A, 7pgc:B, 7vlg:A, 7vlg:B, 7vlh:A, 7vlh:B, 7vli:A, 7vli:B, 7vxx:D, 7vxy:C, 7vxy:D, 6y3b:A, 6y3b:B, 8y9v:C, 8y9v:D, 5yof:A, 5yof:B, 7zlc:A, 7zlc:B, 7zld:A, 7zld:B, 5zmq:C, 5zmq:D, 5zmq:G, 5zmq:H, 5zms:A, 5zms:B, 5zms:D, 5zms:E, 7zmi:A, 7zmi:B, 7zno:A, 7zno:B, 5zob:A, 5zob:B, 5zob:C, 5zob:D, 7zpd:A, 7zpd:B, 7zq1:B, 7zqf:B, 7ztm:B, 7zum:A, 7zum:B, 7zv4:A, 7zv4:B, 7zvv:B, 7zvv:A, 7zw5:A, 7zw5:B, 7zwk:A, 7zwk:B, 7zys:A, 7zys:B
18 3u1i:B 168 26 0.0187 0.0774 0.5000 4.6 3u1i:D, 3u1j:B
19 2wtk:C 285 86 0.0359 0.0877 0.2907 5.0 2wtk:F
20 2vbc:A 600 26 0.0172 0.0200 0.4615 5.7 2jlr:A, 2jls:A, 2jlu:A, 2jlu:B, 2jlv:A, 2jlv:B, 2jlw:A, 2jlw:B, 2jlx:A, 2jlx:B, 2jly:A, 2jly:B, 2jlz:A, 2jlz:B, 2whx:A, 2wzq:A, 5xc6:A, 5xc6:B, 5yvj:B
21 1zq1:A 437 46 0.0244 0.0389 0.3696 6.1 1zq1:B
22 2vf8:B 835 69 0.0287 0.0240 0.2899 6.5 2vf7:A, 2vf7:C
23 2vf7:B 813 69 0.0287 0.0246 0.2899 6.5 2vf8:A
24 3gdv:B 284 88 0.0416 0.1021 0.3295 6.6 3gdu:B, 2r3y:A, 4rqz:A, 4rqz:B, 4rqz:C
25 6phv:A 721 54 0.0301 0.0291 0.3889 7.1 6phw:A, 6phx:A, 6phy:A, 6pi0:A
26 4mvn:D 200 43 0.0215 0.0750 0.3488 7.2 4mvn:A, 4mvn:B, 4mvn:C, 3ufa:A, 3ufa:B
27 2pok:A 458 59 0.0273 0.0415 0.3220 8.1 2pok:B
28 8hvr:H 158 57 0.0258 0.1139 0.3158 8.8 8jke:H
29 2yol:A 212 26 0.0172 0.0566 0.4615 9.2 3e90:B, 3e90:D, 2fp7:A, 2fp7:B, 5idk:A, 5idk:B, 5idk:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218