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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GDVGAGEQIFNANCAACHAGGQNVIMPEKTLEKEALDQYLAGGRTEKSIISQVTGGKNAMPAFGGRLSDEEIANVAAYVL
ASAEAGW

The query sequence (length=87) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3dmi:A 87 87 1.0000 1.0000 1.0000 3.32e-60
2 7y5e:GN 84 86 0.6207 0.6429 0.6279 7.95e-34 7y5e:G2, 7y7a:G7, 7y7a:Go
3 2zbo:A 86 88 0.5977 0.6047 0.5909 8.51e-33 2zbo:C, 2zbo:E, 2zbo:G, 2zbo:I, 2zbo:K
4 1c6s:A 87 86 0.5862 0.5862 0.5930 1.97e-31 6tr1:A, 6tr1:C, 6tr1:E, 6tsy:A, 6tsy:B, 6tsy:C, 6tsy:D, 6tsy:E, 6tsy:F
5 1cyj:A 90 87 0.5977 0.5778 0.5977 2.05e-31 1cyi:A
6 1gdv:A 85 86 0.5632 0.5765 0.5698 2.05e-30
7 1kib:A 89 89 0.5747 0.5618 0.5618 1.58e-29 1f1f:A, 1kib:B, 1kib:C, 1kib:D, 1kib:E, 1kib:F, 1kib:G, 1kib:H
8 4gyd:A 86 82 0.5402 0.5465 0.5732 4.07e-29 4gyd:B, 4gyd:C, 4gyd:D, 4gyd:E, 4gyd:F, 4h0j:A, 4h0j:B, 4h0j:C, 4h0j:D, 4h0j:E, 4h0j:F, 4h0k:A, 4h0k:B
9 3ph2:B 85 86 0.5517 0.5647 0.5581 8.72e-29 2v08:A, 2v08:B
10 1c6o:A 89 82 0.5172 0.5056 0.5488 5.26e-27 1c6o:B, 1c6r:A
11 3dr0:A 93 77 0.5287 0.4946 0.5974 1.59e-26 3dr0:B, 3dr0:C, 4eic:A, 4eid:A
12 1a2s:A 89 82 0.4828 0.4719 0.5122 4.07e-26 1ced:A, 1ctj:A
13 1ls9:A 91 78 0.4253 0.4066 0.4744 2.61e-22
14 4eie:A 82 82 0.3908 0.4146 0.4146 3.05e-15 4eif:A
15 2dge:A 102 98 0.4023 0.3431 0.3571 5.73e-12 2ce0:A, 2ce1:A, 2dge:C, 2dge:B, 2dge:D, 2v07:A
16 7o38:A 81 72 0.3103 0.3333 0.3750 8.18e-09
17 3dp5:A 99 78 0.2874 0.2525 0.3205 2.10e-07 3cu4:A, 5mcs:A, 6u97:A
18 2zon:G 81 81 0.3333 0.3580 0.3580 3.23e-07
19 8hn3:A 80 78 0.3103 0.3375 0.3462 1.07e-06 8hn3:B
20 4kmg:A 88 89 0.2989 0.2955 0.2921 1.27e-05
21 4j20:A 88 87 0.3103 0.3068 0.3103 1.62e-05 4j20:B
22 8yts:A 83 85 0.3333 0.3494 0.3412 3.16e-05 8yts:B
23 7e1w:O 223 85 0.3218 0.1256 0.3294 1.15e-04 7e1v:O, 7e1v:C, 7e1w:C, 7e1x:O, 7e1x:C, 8hcr:C, 8hcr:O
24 8wql:VD 135 97 0.2989 0.1926 0.2680 1.29e-04 1f1c:A, 1f1c:B, 8wql:VE, 8wql:V1, 8wql:v1, 8wql:vD, 8wql:vE
25 6hwh:i 162 85 0.3218 0.1728 0.3294 1.49e-04 6hwh:j
26 6adq:C 223 85 0.3218 0.1256 0.3294 1.60e-04 6adq:O, 6hwh:M, 6hwh:K, 8ovc:O, 8ovc:C, 8ovd:O, 8ovd:C, 7rh5:O, 7rh5:I, 7rh6:O, 7rh6:I, 7rh7:O, 7rh7:I
27 6jlu:V 137 34 0.1839 0.1168 0.4706 3.15e-04 8iwh:V, 8iwh:v, 6j3y:V, 6j3y:v, 6j3z:V, 6j3z:v, 6j40:V, 6j40:v, 8j5k:V, 8j5k:v, 6jlu:v, 7vd5:V, 7vd5:v
28 2zzs:A 81 74 0.2874 0.3086 0.3378 3.17e-04 2zzs:B, 2zzs:C, 2zzs:D, 2zzs:E, 2zzs:F, 2zzs:G, 2zzs:H, 2zzs:I, 2zzs:J, 2zzs:K, 2zzs:L, 2zzs:M, 2zzs:N, 2zzs:O, 2zzs:P, 2zzs:Q, 2zzs:R, 2zzs:S, 2zzs:T, 2zzs:U, 2zzs:V, 2zzs:W, 2zzs:X, 2zzs:Y, 2zzs:Z, 2zzs:1, 2zzs:2, 2zzs:3, 2zzs:4, 2zzs:5, 2zzs:6
29 4lji:A 133 101 0.2644 0.1729 0.2277 4.16e-04 4lji:B
30 8smr:G 312 82 0.2759 0.0769 0.2927 5.70e-04
31 8smr:G 312 87 0.2989 0.0833 0.2989 0.083
32 6btm:E 161 83 0.3218 0.1739 0.3373 0.002
33 1gks:A 78 85 0.2414 0.2692 0.2471 0.002
34 7y5e:VL 134 34 0.1609 0.1045 0.4118 0.002 7y5e:V6, 7y5e:v6, 7y5e:vL, 7y7a:V9, 7y7a:v9, 7y7a:VE, 7y7a:vE, 7y7a:VO, 7y7a:vO, 7y7a:VZ, 7y7a:vZ, 7y7a:Vm, 7y7a:vm
35 8xr6:V 137 34 0.1609 0.1022 0.4118 0.003 8wb4:V, 8wb4:v, 8xr6:v
36 1kv9:A 664 81 0.2299 0.0301 0.2469 0.004
37 8snh:G 304 90 0.3103 0.0888 0.3000 0.005
38 8snh:G 304 75 0.2759 0.0789 0.3200 0.012
39 4yuu:V1 129 31 0.1379 0.0930 0.3871 0.007 4yuu:v1, 4yuu:V2, 4yuu:v2
40 5djq:C 303 78 0.2759 0.0792 0.3077 0.017 5djq:M, 5djq:F, 5djq:I, 3mk7:C, 3mk7:M, 3mk7:F, 3mk7:I
41 5djq:C 303 86 0.2759 0.0792 0.2791 0.26 5djq:M, 5djq:F, 5djq:I, 3mk7:C, 3mk7:M, 3mk7:F, 3mk7:I
42 6f0k:E 182 89 0.2759 0.1319 0.2697 0.019
43 2zoo:A 438 86 0.3218 0.0639 0.3256 0.028
44 7qhm:C 233 84 0.2759 0.1030 0.2857 0.035 7q21:C, 7q21:c, 7qhm:P, 7qho:C, 7qho:P
45 8eqm:V 131 31 0.1609 0.1069 0.4516 0.042 8eqm:v
46 4ax3:D 457 92 0.3218 0.0613 0.3043 0.044 4ax3:A, 4ax3:B, 4ax3:C, 6f1q:A, 6fja:A, 5obo:A, 5ocb:A, 5ocf:A, 8qgf:A, 6qpt:A, 6qpt:B, 6qpt:C, 6qpt:D, 6qpt:E, 6qpt:F, 6qpu:A, 6qpu:B, 6qpu:C, 6qpu:D, 6qpu:E, 6qpu:F, 6qpv:A, 6qpv:I, 6qpx:A, 6qpx:I, 6qpz:A, 6qpz:I, 6qq0:A, 6qq1:A, 6qq2:A, 7qq2:A, 7r2u:A, 2yqb:A, 3zbm:A, 3ziy:A
47 6r6m:B 100 35 0.1494 0.1300 0.3714 0.077 6r6n:B, 6r6o:B
48 2yev:B 319 84 0.3103 0.0846 0.3214 0.088 2yev:E
49 3cp5:A 116 22 0.1264 0.0948 0.5000 0.10 6cuk:A, 6cun:A
50 3a0b:V 137 31 0.1379 0.0876 0.3871 0.11 3a0b:v, 3a0h:V, 3a0h:v, 2axt:V, 2axt:v, 5b5e:V, 5b5e:v, 5b66:V, 5b66:v, 7cji:V, 7cji:v, 7cjj:V, 7cjj:v, 7cou:V, 7cou:v, 7d1t:V, 7d1t:v, 7d1u:V, 7d1u:v, 6dhe:V, 6dhe:v, 6dhf:V, 6dhf:v, 6dhg:V, 6dhg:v, 6dhh:V, 6dhh:v, 6dho:V, 6dho:v, 6dhp:V, 6dhp:v, 5e79:V, 5e79:v, 5e7c:V, 5e7c:v, 7eda:V, 9evx:V, 9evx:v, 8ez5:V, 8ez5:v, 8f4c:V, 8f4c:v, 8f4d:V, 8f4d:v, 8f4e:V, 8f4e:v, 8f4f:V, 8f4f:v, 8f4g:V, 8f4g:v, 8f4h:V, 8f4h:v, 8f4i:V, 8f4i:v, 8f4j:V, 8f4j:v, 8f4k:V, 8f4k:v, 4fby:V, 4fby:i, 8gn0:V, 8gn0:v, 8gn1:V, 8gn1:v, 8gn2:V, 8gn2:v, 5gth:V, 5gth:v, 5gti:V, 5gti:v, 5h2f:V, 5h2f:v, 4il6:V, 4il6:v, 8ir5:V, 8ir5:v, 8ir6:V, 8ir6:v, 8ir7:V, 8ir7:v, 8ir8:V, 8ir8:v, 8ir9:V, 8ir9:v, 8ira:V, 8ira:v, 8irb:V, 8irb:v, 8irc:V, 8irc:v, 8ird:V, 8ird:v, 8ire:V, 8ire:v, 8irf:V, 8irf:v, 8irg:V, 8irg:v, 8irh:V, 8irh:v, 8iri:V, 8iri:v, 4ixq:V, 4ixq:v, 4ixr:V, 4ixr:v, 1izl:V, 1izl:0, 6jlj:V, 6jlj:v, 6jlk:V, 6jlk:v, 6jll:V, 6jll:v, 6jlm:V, 6jlm:v, 6jln:V, 6jln:v, 6jlo:V, 6jlo:v, 6jlp:V, 6jlp:v, 5kaf:V, 5kaf:v, 5kai:V, 5kai:v, 3kzi:V, 5mx2:V, 5mx2:v, 1mz4:A, 4pbu:V, 4pbu:v, 4pj0:V, 4pj0:v, 7rf1:V, 7rf1:v, 7rf2:V, 7rf2:v, 7rf3:V, 7rf3:v, 7rf4:V, 7rf4:v, 7rf5:V, 7rf5:v, 7rf6:V, 7rf6:v, 7rf7:V, 7rf7:v, 7rf8:V, 7rf8:v, 4rvy:V, 4rvy:v, 1s5l:V, 1s5l:v, 5tis:V, 5tis:v, 4tnh:V, 4tnh:v, 4tni:V, 4tni:v, 4tnj:V, 4tnj:v, 4tnk:V, 4tnk:v, 4ub6:V, 4ub6:v, 4ub8:V, 4ub8:v, 5v2c:V, 5v2c:v, 4v62:AV, 4v62:BV, 4v82:AV, 4v82:BV, 6w1o:V, 6w1o:v, 6w1p:V, 6w1p:v, 6w1q:V, 6w1q:v, 6w1r:V, 6w1r:v, 6w1t:V, 6w1t:v, 6w1u:V, 6w1u:v, 6w1v:V, 6w1v:v, 1w5c:T, 1w5c:V, 5ws5:V, 5ws5:v, 5ws6:V, 5ws6:v, 3wu2:V, 3wu2:v, 7yq2:V, 7yq2:v, 7yq7:V, 7yq7:v, 5zzn:V, 5zzn:v
51 1wve:C 75 77 0.2644 0.3067 0.2987 0.13 1dii:C, 1dii:D, 1diq:C, 1diq:D, 1wve:D
52 2xts:D 204 18 0.1149 0.0490 0.5556 0.16 2xts:B
53 2l4d:A 106 17 0.1034 0.0849 0.5294 0.18
54 1kx2:A 81 68 0.2529 0.2716 0.3235 0.25 1kx7:A
55 8gy2:B 433 97 0.3218 0.0647 0.2887 0.25
56 8gy3:A 440 82 0.2759 0.0545 0.2927 0.25
57 6h5l:B 220 44 0.1609 0.0636 0.3182 0.27
58 1ccr:A 111 19 0.1149 0.0901 0.5263 0.28
59 1akk:A 104 30 0.1494 0.1250 0.4333 0.34 2b4z:A, 5c0z:A, 5c0z:D, 5c0z:B, 5c0z:C, 5c9m:A, 5c9m:D, 5c9m:B, 5c9m:C, 1crc:A, 1crc:B, 5df5:A, 5df5:B, 5df5:C, 5df5:D, 8dvx:A, 8dvx:D, 8dvx:B, 8dvx:C, 8dzl:A, 8dzl:B, 8dzl:C, 8dzl:D, 6ff5:A, 1fi7:A, 1fi9:A, 2frc:A, 1giw:A, 2giw:A, 1hrc:A, 1i5t:A, 5iy5:1, 5iy5:2, 3j2t:H, 3j2t:I, 3j2t:J, 3j2t:K, 3j2t:L, 3j2t:M, 3j2t:N, 3jbt:B, 3jbt:D, 3jbt:F, 3jbt:H, 3jbt:J, 3jbt:L, 3jbt:N, 5juy:H, 5juy:I, 5juy:J, 5juy:K, 5juy:L, 5juy:M, 5juy:N, 6k9i:A, 6k9j:A, 1lc1:A, 1lc2:A, 7ljx:A, 7ljx:B, 1m60:A, 6n1o:A, 6n1o:B, 6n1o:C, 6n1o:D, 2n3b:A, 3nbs:A, 3nbs:B, 3nbs:C, 3nbs:D, 3nbt:A, 3nbt:E, 3nbt:B, 3nbt:C, 3nbt:D, 3nbt:F, 4nfg:B, 3o1y:A, 3o1y:B, 3o1y:C, 3o20:A, 3o20:B, 3o20:C, 1ocd:A, 2pcb:B, 4rsz:A, 4rsz:B, 4rsz:C, 4rsz:D, 4rsz:E, 4rsz:F, 6suv:AaA, 6suv:BaB, 6suv:CaC, 6suv:DaD, 6suv:EaE, 6suv:FaF, 6suv:GaG, 6suv:HaH, 1u75:B, 3wc8:A, 1wej:F, 3wui:A, 5wve:B, 5wve:D, 5wve:F, 5wve:H, 5wve:J, 5wve:L, 5wve:N, 2ybb:Y, 5zkv:A
60 1cyc:A 103 30 0.1379 0.1165 0.4000 0.44 1cyc:B, 3cyt:O, 3cyt:I, 5cyt:R, 1i54:A, 1i54:B, 1i55:A, 1i55:B, 1lfm:A, 1lfm:B
61 2aiu:A 104 30 0.1494 0.1250 0.4333 0.51
62 6xkw:p 254 84 0.3333 0.1142 0.3452 0.53 6xkx:p, 6xkz:p
63 6xkw:p 254 75 0.2529 0.0866 0.2933 1.7 6xkx:p, 6xkz:p
64 8uf3:A 187 81 0.2874 0.1337 0.3086 0.67 8uf3:B
65 4dy9:A 108 30 0.1494 0.1204 0.4333 0.88 4ged:B
66 5dfs:A 104 30 0.1379 0.1154 0.4000 0.89 5dfs:B, 6duj:A, 6duj:C, 6ecj:A, 6ecj:B, 6ecj:C, 6ecj:D, 6ecj:E, 6ecj:F, 6ecj:G, 6ecj:H, 5exq:A, 5exq:B, 1j3s:A, 2n3y:A, 2n9i:A, 2n9j:A, 3nwv:A, 3nwv:B, 3nwv:C, 3nwv:D, 5o10:A, 5o10:B, 5ty3:A, 5ty3:B, 6xnk:A, 6xnk:C, 6xnk:E, 6xnk:G, 3zcf:A, 3zcf:B, 3zcf:C, 3zcf:D, 3zoo:A, 3zoo:B, 3zoo:C, 3zoo:D
67 7c90:A 151 81 0.2529 0.1457 0.2716 0.94 7c90:B, 7c90:C, 7c90:D
68 1mxs:A 216 45 0.1609 0.0648 0.3111 1.4
69 7vzg:C 193 79 0.2529 0.1140 0.2785 1.8 7vzr:C
70 1n83:A 251 22 0.1149 0.0398 0.4545 1.9 1s0x:A, 4s15:A, 4s15:B
71 7u2v:A 114 19 0.0920 0.0702 0.4211 2.2 7u2v:B
72 7w2j:C 418 93 0.2874 0.0598 0.2688 2.2 8jej:C, 8jek:C, 8k6j:C, 8k6k:C, 7w2j:F, 7wsq:C, 7wsq:F, 8xcm:C, 8xcn:C
73 7txe:A 131 19 0.0920 0.0611 0.4211 2.4 7txe:B
74 6onq:A 159 63 0.1839 0.1006 0.2540 3.1
75 8smr:K 181 71 0.2414 0.1160 0.2958 3.1 6q2u:A, 8smr:N, 8snh:K, 8snh:N
76 5ey5:B 383 45 0.1839 0.0418 0.3556 3.2 5ey5:D
77 4v2k:A 235 83 0.3103 0.1149 0.3253 3.3 4wq7:A, 4wq8:A, 4wq9:A, 4wqa:A, 4wqb:A, 4wqc:A, 4wqd:A, 4wqe:A
78 6qhd:B 532 42 0.1724 0.0282 0.3571 4.1
79 1bg1:A 559 42 0.1724 0.0268 0.3571 4.1 4e68:A, 6njs:A, 6nuq:A, 6qhd:A
80 2yk3:A 110 30 0.1379 0.1091 0.4000 4.3 2yk3:B, 2yk3:C
81 7aor:j 180 28 0.1149 0.0556 0.3571 4.6
82 6hiv:CP 180 28 0.0920 0.0444 0.2857 5.6 6hiw:CP, 6hiy:CP, 7pua:CP, 7pub:CP, 6sga:CP, 6sgb:CP
83 1kb0:A 670 27 0.1034 0.0134 0.3333 6.0
84 1l3w:A 540 37 0.1609 0.0259 0.3784 7.4 1q55:A, 1q55:B, 1q55:C, 1q55:D, 1q5a:A, 1q5a:B, 1q5b:A, 1q5b:B, 1q5b:C, 1q5c:A, 1q5c:B, 1q5c:C, 1q5c:D
85 8hdd:B 121 85 0.2759 0.1983 0.2824 8.9
86 8b6j:D 295 19 0.1034 0.0305 0.4737 9.4 8b6j:d, 8bqs:D, 8bqs:d, 8gym:qD, 8gym:qd, 8gym:Qd, 8gym:QD, 8gzu:qD, 8gzu:qd, 8gzu:QD, 8gzu:Qd, 7tgh:3D, 7tgh:3d

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218