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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFSYTDANKNKGITWGEETLMEYLENPKKYIPGTKM
IFAGIKKKGEREDLIAYLKKATNE

The query sequence (length=104) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1akk:A 104 104 0.9712 0.9712 0.9712 4.21e-71 2b4z:A, 5c0z:A, 5c0z:D, 5c0z:B, 5c0z:C, 5c9m:A, 5c9m:D, 5c9m:B, 5c9m:C, 1crc:A, 1crc:B, 5df5:A, 5df5:B, 5df5:C, 5df5:D, 8dvx:A, 8dvx:D, 8dvx:B, 8dvx:C, 8dzl:A, 8dzl:B, 8dzl:C, 8dzl:D, 6ff5:A, 1fi7:A, 1fi9:A, 2frc:A, 1giw:A, 2giw:A, 1hrc:A, 1i5t:A, 5iy5:1, 5iy5:2, 3j2t:H, 3j2t:I, 3j2t:J, 3j2t:K, 3j2t:L, 3j2t:M, 3j2t:N, 3jbt:B, 3jbt:D, 3jbt:F, 3jbt:H, 3jbt:J, 3jbt:L, 3jbt:N, 5juy:H, 5juy:I, 5juy:J, 5juy:K, 5juy:L, 5juy:M, 5juy:N, 6k9i:A, 6k9j:A, 1lc1:A, 1lc2:A, 7ljx:A, 7ljx:B, 1m60:A, 6n1o:A, 6n1o:B, 6n1o:C, 6n1o:D, 2n3b:A, 3nbs:A, 3nbs:B, 3nbs:C, 3nbs:D, 3nbt:A, 3nbt:E, 3nbt:B, 3nbt:C, 3nbt:D, 3nbt:F, 4nfg:B, 3o1y:A, 3o1y:B, 3o1y:C, 3o20:A, 3o20:B, 3o20:C, 1ocd:A, 2pcb:B, 4rsz:A, 4rsz:B, 4rsz:C, 4rsz:D, 4rsz:E, 4rsz:F, 6suv:AaA, 6suv:BaB, 6suv:CaC, 6suv:DaD, 6suv:EaE, 6suv:FaF, 6suv:GaG, 6suv:HaH, 1u75:B, 3wc8:A, 1wej:F, 3wui:A, 5wve:B, 5wve:D, 5wve:F, 5wve:H, 5wve:J, 5wve:L, 5wve:N, 2ybb:Y, 5zkv:A
2 2aiu:A 104 103 0.8942 0.8942 0.9029 3.32e-66
3 5dfs:A 104 104 0.8846 0.8846 0.8846 7.23e-66 5dfs:B, 6duj:A, 6duj:C, 6ecj:A, 6ecj:B, 6ecj:C, 6ecj:D, 6ecj:E, 6ecj:F, 6ecj:G, 6ecj:H, 5exq:A, 5exq:B, 1j3s:A, 2n3y:A, 2n9i:A, 2n9j:A, 3nwv:A, 3nwv:B, 3nwv:C, 3nwv:D, 5o10:A, 5o10:B, 5ty3:A, 5ty3:B, 6xnk:A, 6xnk:C, 6xnk:E, 6xnk:G, 3zcf:A, 3zcf:B, 3zcf:C, 3zcf:D, 3zoo:A, 3zoo:B, 3zoo:C, 3zoo:D
4 1cyc:A 103 103 0.8462 0.8544 0.8544 2.81e-62 1cyc:B, 3cyt:O, 3cyt:I, 5cyt:R, 1i54:A, 1i54:B, 1i55:A, 1i55:B, 1lfm:A, 1lfm:B
5 1ccr:A 111 103 0.6250 0.5856 0.6311 4.32e-46
6 2b0z:B 108 101 0.6154 0.5926 0.6337 1.59e-44 2b10:B, 2b10:D, 2b11:B, 2b11:D, 2b12:B, 7bbt:A, 7bbt:B, 7bbt:C, 7bbt:D, 2bcn:B, 1chh:A, 1chi:A, 1chj:A, 1cie:A, 1cif:A, 1cig:A, 1cih:A, 5cib:B, 5cib:D, 5cic:B, 5cic:D, 5cid:B, 5cid:D, 5cie:B, 5cie:D, 5cif:B, 5cif:D, 5cig:B, 5cig:D, 5cih:B, 5cih:D, 1crg:A, 1crh:A, 1cri:A, 1crj:A, 1csu:A, 1csv:A, 1csw:A, 1csx:A, 1cty:A, 1ctz:A, 3cx5:W, 6egy:A, 6egy:B, 6egz:A, 6egz:B, 1fhb:A, 2gb8:B, 6gd6:A, 6gd7:A, 6gd8:A, 6gd8:C, 6gd8:B, 6gd8:D, 6gd9:A, 6gda:A, 2hv4:A, 1irv:A, 1irw:A, 2jqr:A, 2jti:B, 5kke:A, 5klu:A, 5klu:B, 5kpf:A, 5kpf:B, 1kyo:W, 5lft:A, 2lir:A, 2lit:A, 1lms:A, 5lyc:A, 5lyc:B, 2mhm:A, 7mri:A, 7mri:C, 7mri:E, 4mu8:A, 4mu8:B, 4n0k:A, 4n0k:B, 2n18:B, 2n18:C, 5ncv:A, 5ncv:B, 1nmi:A, 2orl:A, 4p4q:B, 4p4q:D, 6p41:B, 6p41:D, 6p42:B, 6p42:D, 6p43:B, 2pcc:B, 2pcc:D, 7pr2:A, 7pr2:B, 7pr3:A, 7pr3:D, 7pr3:C, 7pr3:B, 7pr4:A, 4q5p:A, 4q5p:B, 4q5p:C, 4qao:A, 4qao:B, 4qao:C, 1rap:A, 1raq:A, 6rsi:A, 6rsj:A, 6rsk:A, 6rsk:B, 6rsl:A, 6rsl:B, 1s6v:B, 1s6v:D, 6s8y:A, 6suy:A, 6suy:B, 5t7h:A, 5t7h:D, 5t7h:B, 5t7h:C, 5t8w:A, 5t8w:B, 3tyi:A, 3tyi:B, 1u74:B, 1u74:D, 6y0j:A, 6y0j:B, 6y0j:C, 6y0j:D, 1ycc:A, 2ycc:A, 4ye1:A, 4ye1:B, 1yfc:A, 1yic:A
7 3cxh:W 112 101 0.5865 0.5446 0.6040 1.91e-44 1yea:A, 1yeb:A, 1ytc:A
8 6c4w:A 109 102 0.5865 0.5596 0.5980 1.02e-42
9 4dy9:A 108 99 0.5385 0.5185 0.5657 1.36e-37 4ged:B
10 1co6:A 107 99 0.5192 0.5047 0.5455 7.75e-36 1cry:A, 1io3:A
11 2yk3:A 110 99 0.5000 0.4727 0.5253 1.14e-35 2yk3:B, 2yk3:C
12 6rgi:A 92 102 0.5288 0.5978 0.5392 3.74e-34
13 8ed4:I 105 101 0.5096 0.5048 0.5248 1.89e-28 8ed4:J, 8ed4:K, 8ed4:L
14 7tlx:1 102 102 0.4135 0.4216 0.4216 1.40e-26
15 1hro:A 105 99 0.4231 0.4190 0.4444 1.76e-26 1hro:B
16 1qn2:A 99 100 0.4327 0.4545 0.4500 2.70e-24 1qn2:B, 1qn2:C
17 3m97:X 118 98 0.4135 0.3644 0.4388 6.15e-22 1c7m:A, 1i6d:A, 1i6e:A, 1ql3:A, 1ql3:B, 1ql3:C, 1ql3:D, 1ql4:A, 1ql4:B, 1ql4:C, 1ql4:D
18 2c2c:A 112 110 0.3942 0.3661 0.3727 1.51e-18 3c2c:A
19 1jdl:A 118 117 0.3846 0.3390 0.3419 2.40e-17
20 2bh4:X 121 88 0.3654 0.3140 0.4318 9.67e-15 2bgv:X, 2bh5:X
21 7u2v:A 114 104 0.3462 0.3158 0.3462 1.68e-14 7u2v:B
22 155c:A 134 118 0.4327 0.3358 0.3814 2.15e-14 1cot:A
23 7txe:A 131 112 0.3365 0.2672 0.3125 4.01e-14 7txe:B
24 1fj0:A 114 114 0.3462 0.3158 0.3158 7.21e-14 1fj0:B, 1fj0:C, 1fj0:D, 1hh7:A, 1i8o:A, 1i8p:A, 1i8p:B, 1i8p:C, 1i8p:D
25 1cxa:A 124 119 0.3942 0.3306 0.3445 1.23e-11 1cxc:A, 2cxb:A, 2cxb:B, 1l9b:C, 1l9j:C, 1l9j:D
26 1c2n:A 116 115 0.4038 0.3621 0.3652 4.62e-11 1c2r:A, 1c2r:B, 1vyd:A, 1vyd:B
27 2yev:B 319 97 0.2885 0.0940 0.3093 1.27e-04 2yev:E
28 7zs0:A 278 74 0.2212 0.0827 0.3108 5.15e-04 7zs1:A, 7zs2:A
29 8xr6:V 137 72 0.2404 0.1825 0.3472 0.002 8wb4:V, 8wb4:v, 8xr6:v
30 1e29:A 135 69 0.2308 0.1778 0.3478 0.003 7n8o:V, 7n8o:v, 7rcv:V, 7rcv:v, 8tow:V, 8tow:v
31 4yuu:V1 129 72 0.1923 0.1550 0.2778 0.006 4yuu:v1, 4yuu:V2, 4yuu:v2
32 7y5e:VL 134 72 0.2212 0.1716 0.3194 0.009 7y5e:V6, 7y5e:v6, 7y5e:vL, 7y7a:V9, 7y7a:v9, 7y7a:VE, 7y7a:vE, 7y7a:VO, 7y7a:vO, 7y7a:VZ, 7y7a:vZ, 7y7a:Vm, 7y7a:vm
33 6jlu:V 137 72 0.2019 0.1533 0.2917 0.034 8iwh:V, 8iwh:v, 6j3y:V, 6j3y:v, 6j3z:V, 6j3z:v, 6j40:V, 6j40:v, 8j5k:V, 8j5k:v, 6jlu:v, 7vd5:V, 7vd5:v
34 2l4d:A 106 113 0.2692 0.2642 0.2478 0.045
35 8snh:G 304 32 0.1538 0.0526 0.5000 0.054
36 8wql:VD 135 73 0.1923 0.1481 0.2740 0.056 1f1c:A, 1f1c:B, 8wql:VE, 8wql:V1, 8wql:v1, 8wql:vD, 8wql:vE
37 1gdv:A 85 31 0.1058 0.1294 0.3548 0.26
38 8smr:G 312 32 0.1250 0.0417 0.4062 0.30
39 3a0b:V 137 28 0.1250 0.0949 0.4643 0.36 3a0b:v, 3a0h:V, 3a0h:v, 2axt:V, 2axt:v, 5b5e:V, 5b5e:v, 5b66:V, 5b66:v, 7cji:V, 7cji:v, 7cjj:V, 7cjj:v, 7cou:V, 7cou:v, 7d1t:V, 7d1t:v, 7d1u:V, 7d1u:v, 6dhe:V, 6dhe:v, 6dhf:V, 6dhf:v, 6dhg:V, 6dhg:v, 6dhh:V, 6dhh:v, 6dho:V, 6dho:v, 6dhp:V, 6dhp:v, 5e79:V, 5e79:v, 5e7c:V, 5e7c:v, 7eda:V, 9evx:V, 9evx:v, 8ez5:V, 8ez5:v, 8f4c:V, 8f4c:v, 8f4d:V, 8f4d:v, 8f4e:V, 8f4e:v, 8f4f:V, 8f4f:v, 8f4g:V, 8f4g:v, 8f4h:V, 8f4h:v, 8f4i:V, 8f4i:v, 8f4j:V, 8f4j:v, 8f4k:V, 8f4k:v, 4fby:V, 4fby:i, 8gn0:V, 8gn0:v, 8gn1:V, 8gn1:v, 8gn2:V, 8gn2:v, 5gth:V, 5gth:v, 5gti:V, 5gti:v, 5h2f:V, 5h2f:v, 4il6:V, 4il6:v, 8ir5:V, 8ir5:v, 8ir6:V, 8ir6:v, 8ir7:V, 8ir7:v, 8ir8:V, 8ir8:v, 8ir9:V, 8ir9:v, 8ira:V, 8ira:v, 8irb:V, 8irb:v, 8irc:V, 8irc:v, 8ird:V, 8ird:v, 8ire:V, 8ire:v, 8irf:V, 8irf:v, 8irg:V, 8irg:v, 8irh:V, 8irh:v, 8iri:V, 8iri:v, 4ixq:V, 4ixq:v, 4ixr:V, 4ixr:v, 1izl:V, 1izl:0, 6jlj:V, 6jlj:v, 6jlk:V, 6jlk:v, 6jll:V, 6jll:v, 6jlm:V, 6jlm:v, 6jln:V, 6jln:v, 6jlo:V, 6jlo:v, 6jlp:V, 6jlp:v, 5kaf:V, 5kaf:v, 5kai:V, 5kai:v, 3kzi:V, 5mx2:V, 5mx2:v, 1mz4:A, 4pbu:V, 4pbu:v, 4pj0:V, 4pj0:v, 7rf1:V, 7rf1:v, 7rf2:V, 7rf2:v, 7rf3:V, 7rf3:v, 7rf4:V, 7rf4:v, 7rf5:V, 7rf5:v, 7rf6:V, 7rf6:v, 7rf7:V, 7rf7:v, 7rf8:V, 7rf8:v, 4rvy:V, 4rvy:v, 1s5l:V, 1s5l:v, 5tis:V, 5tis:v, 4tnh:V, 4tnh:v, 4tni:V, 4tni:v, 4tnj:V, 4tnj:v, 4tnk:V, 4tnk:v, 4ub6:V, 4ub6:v, 4ub8:V, 4ub8:v, 5v2c:V, 5v2c:v, 4v62:AV, 4v62:BV, 4v82:AV, 4v82:BV, 6w1o:V, 6w1o:v, 6w1p:V, 6w1p:v, 6w1q:V, 6w1q:v, 6w1r:V, 6w1r:v, 6w1t:V, 6w1t:v, 6w1u:V, 6w1u:v, 6w1v:V, 6w1v:v, 1w5c:T, 1w5c:V, 5ws5:V, 5ws5:v, 5ws6:V, 5ws6:v, 3wu2:V, 3wu2:v, 7yq2:V, 7yq2:v, 7yq7:V, 7yq7:v, 5zzn:V, 5zzn:v
40 6kls:C 236 112 0.2308 0.1017 0.2143 0.45 6kls:F, 6klv:C, 6klv:F
41 3dmi:A 87 30 0.1250 0.1494 0.4333 0.51
42 7y5e:GN 84 29 0.1058 0.1310 0.3793 0.53 7y5e:G2, 7y7a:G7, 7y7a:Go
43 8uf3:A 187 21 0.0962 0.0535 0.4762 0.54 8uf3:B
44 6hwh:i 162 30 0.1250 0.0802 0.4333 0.59 6hwh:j
45 6hwh:i 162 50 0.1442 0.0926 0.3000 1.3 6hwh:j
46 6adq:C 223 30 0.1250 0.0583 0.4333 0.60 6adq:O, 6hwh:M, 6hwh:K, 8ovc:O, 8ovc:C, 8ovd:O, 8ovd:C, 7rh5:O, 7rh5:I, 7rh6:O, 7rh6:I, 7rh7:O, 7rh7:I
47 6adq:C 223 50 0.1442 0.0673 0.3000 1.2 6adq:O, 6hwh:M, 6hwh:K, 8ovc:O, 8ovc:C, 8ovd:O, 8ovd:C, 7rh5:O, 7rh5:I, 7rh6:O, 7rh6:I, 7rh7:O, 7rh7:I
48 2xts:D 204 18 0.0865 0.0441 0.5000 0.60 2xts:B
49 7e1w:O 223 50 0.1442 0.0673 0.3000 0.75 7e1v:O, 7e1v:C, 7e1w:C, 7e1x:O, 7e1x:C, 8hcr:C, 8hcr:O
50 7qhm:C 233 33 0.1058 0.0472 0.3333 0.78 7q21:C, 7q21:c, 7qhm:P, 7qho:C, 7qho:P
51 7qhm:C 233 35 0.1346 0.0601 0.4000 0.92 7q21:C, 7q21:c, 7qhm:P, 7qho:C, 7qho:P
52 1kib:A 89 31 0.1154 0.1348 0.3871 0.89 1f1f:A, 1kib:B, 1kib:C, 1kib:D, 1kib:E, 1kib:F, 1kib:G, 1kib:H
53 5djq:C 303 17 0.0769 0.0264 0.4706 1.8 5djq:M, 5djq:F, 5djq:I, 3mk7:C, 3mk7:M, 3mk7:F, 3mk7:I
54 4gyd:A 86 98 0.2788 0.3372 0.2959 2.2 4gyd:B, 4gyd:C, 4gyd:D, 4gyd:E, 4gyd:F, 4h0j:A, 4h0j:B, 4h0j:C, 4h0j:D, 4h0j:E, 4h0j:F, 4h0k:A, 4h0k:B
55 6x8z:A 158 55 0.1538 0.1013 0.2909 2.6 6x8z:B
56 6h5l:A 506 53 0.1346 0.0277 0.2642 3.2
57 3ph2:B 85 18 0.0769 0.0941 0.4444 3.4 2v08:A, 2v08:B
58 6z7n:H 894 50 0.1827 0.0213 0.3800 3.4 6z7n:G, 6z7n:D, 6z7n:E, 6z7n:F
59 6ok1:B 131 54 0.1635 0.1298 0.3148 3.6 6ok1:D
60 1gc5:A 467 58 0.1635 0.0364 0.2931 3.6 4b8s:A
61 5cgw:A 362 58 0.1731 0.0497 0.3103 3.9 5cgs:A, 5cgx:A, 5chj:A, 5chj:B, 5chm:A, 5chu:B, 5za2:A, 5za2:B
62 5aur:A 83 53 0.1346 0.1687 0.2642 4.2 2ai5:A, 5aur:C, 5aur:E, 5aur:G, 5aus:A, 5aus:C, 1ayg:A, 3vym:A, 1ynr:A, 1ynr:B, 1ynr:C, 1ynr:D, 4zid:A
63 6z7n:B 847 36 0.1442 0.0177 0.4167 4.4
64 6yba:E 917 36 0.1442 0.0164 0.4167 4.4 6yba:F, 6yba:D, 6yba:A, 6yba:C, 6yba:G, 6yba:I, 6yba:B, 6z7n:I, 6z7n:J
65 1gjq:A 541 41 0.1346 0.0259 0.3415 4.8 1bl9:A, 1bl9:B, 1gjq:B, 5guw:M, 5guw:N, 1hzu:A, 1hzv:A, 1n15:A, 1n15:B, 1n50:A, 1n50:B, 1n90:A, 1n90:B, 1nir:A, 1nir:B, 1nno:A, 1nno:B, 6tpo:A, 6tsi:A, 6tsi:B
66 8bel:E 244 20 0.0577 0.0246 0.3000 5.0 8bel:O, 8bpx:AE, 8bpx:BE, 8bq5:AE, 8bq5:BE, 8bq6:AE, 8bq6:BE, 8e73:D, 8e73:P, 7jrg:D, 7jrg:P, 7jrp:D, 7jrp:P
67 5o5z:A 454 58 0.1635 0.0374 0.2931 5.1 5o5y:B, 5o5z:B
68 6lod:E 157 69 0.1635 0.1083 0.2464 5.3 6loe:E
69 7msc:6 60 20 0.0865 0.1500 0.4500 5.6 7kgb:6, 7msh:6, 7msm:6, 7msz:6, 7mt2:6, 7mt3:6, 7mt7:6, 7sfr:6
70 4lji:A 133 29 0.0962 0.0752 0.3448 6.4 4lji:B
71 1c6o:A 89 31 0.1058 0.1236 0.3548 6.8 1c6o:B, 1c6r:A
72 5k6w:A 475 56 0.1635 0.0358 0.3036 7.0 5k6v:A, 5k6w:B
73 1ls9:A 91 16 0.0769 0.0879 0.5000 8.7
74 1cyj:A 90 30 0.0962 0.1111 0.3333 8.8 1cyi:A
75 1c6s:A 87 17 0.0769 0.0920 0.4706 9.4 6tr1:A, 6tr1:C, 6tr1:E, 6tsy:A, 6tsy:B, 6tsy:C, 6tsy:D, 6tsy:E, 6tsy:F
76 2d0w:A 168 36 0.1154 0.0714 0.3333 9.7 2d0w:B
77 1gu6:A 441 19 0.0865 0.0204 0.4737 9.8 1gu6:G, 1gu6:C, 1gu6:E, 3l1t:A, 3l1t:B, 3l1t:C, 3l1t:D, 2rdz:A, 2rdz:B, 2rdz:C, 2rdz:D, 2rf7:A, 2rf7:B, 2rf7:C, 2rf7:D, 3tor:A, 3tor:D, 3tor:B, 3tor:C, 4wjy:A, 4wjy:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218