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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GDVAIYTTTSSLTRDLTRDAVNFSTTITLNPAEQYQTMDGFGAAITGSTCYNLLLMKPADRHAFLTETFSDKDGFGFSYI
RISIGCSDFSLSEYTCCDTKGIENFALQSEEKDYILPILKEILAINPSIKVIAAPWTCPKWMKVKSLTDRTPLDSWTNGQ
LNPDYYQDYATYFVKWIQAFKAEGIDIYAVTPQNEPLNRGNSASLYMEWEEQRDFVKTALGPQMKAAGLSTKIYAFDHNY
NYDNIESQKNYPGKIYEDAAASQYLAGAAYHNYGGNREELLNIHQAYPEKELLFTETSIGTWNSGRDLSKRLMEDMEEVA
LGTINNWCKGVIVWNLMLDNDRGPNREGGCQTCYGAVDINNSDYKTIIRNSHYYIIAHLSSVVKPGAVRIATTGYTDNGI
TCSAFENTDGTYAFVLINNNEKSKKITVSDGQRHFAYDVPGKSVTSYRWAKS

The query sequence (length=452) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5ngl:B 454 453 1.0000 0.9956 0.9978 0.0 5ngl:A, 5ngl:C
2 9fa6:A 501 453 0.2588 0.2335 0.2583 6.13e-46 8awk:AAA, 8awr:AAA, 8ax3:A, 8ax3:B, 9f9z:A, 9fa3:A, 9fad:A, 9fal:A, 9fay:A, 9faz:A, 9fb2:A, 9fdi:A, 3gxf:B, 3gxf:D, 5lvx:C, 5lvx:B, 5lvx:A, 5lvx:D, 6moz:A, 2nsx:A, 2nsx:B, 2nsx:C, 2nsx:D, 2nt0:A, 2nt0:B, 2nt0:C, 2nt0:D, 7nwv:AAA, 7nwv:BBB, 8p3e:B, 8p41:A, 8p41:B, 6q1n:A, 6q1n:B, 6q1p:A, 6q1p:B, 6q6k:A, 6q6k:B, 6q6l:A, 6q6l:B, 6q6n:A, 6q6n:B, 3rik:B, 3rik:D, 3ril:A, 3ril:B, 3ril:C, 3ril:D, 6t13:B, 6t13:C, 6t13:A, 6t13:D, 6tjq:BBB, 6tn1:AAA, 2v3d:A, 2v3d:B, 2v3e:A, 2v3e:B, 2vt0:A, 2vt0:B, 2wcg:A, 2wcg:B, 2xwd:A, 2xwd:B, 2xwe:A, 2xwe:B, 1y7v:A, 1y7v:B, 6ytp:AAA, 6ytp:BBB, 6ytr:AAA, 6ytr:BBB, 6yut:AAA, 6yut:BBB, 6yv3:AAA, 6yv3:BBB, 6z39:AAA, 6z39:BBB, 6z3i:BBB
3 2wnw:B 445 447 0.2544 0.2584 0.2573 7.02e-45 2wnw:A
4 7n6o:A 433 422 0.2279 0.2379 0.2441 7.78e-19 7n6o:B
5 8idp:A 446 422 0.2345 0.2377 0.2512 7.54e-18 8idp:C, 8idp:B, 8idp:D, 8idq:A, 8idq:B, 8idq:C, 8idq:D
6 6m5z:A 433 414 0.2323 0.2425 0.2536 1.23e-17 6m5z:B
7 6krn:A 456 440 0.2168 0.2149 0.2227 3.39e-13
8 4uqa:A 391 429 0.2257 0.2609 0.2378 7.08e-11 5a6l:A, 5a6m:A, 4ckq:A, 4uqc:A
9 2y24:A 383 314 0.1637 0.1932 0.2357 4.25e-10
10 4qaw:A 537 362 0.1947 0.1639 0.2431 1.46e-07 4qaw:B, 4qaw:C, 4qaw:D, 4qaw:E, 4qaw:F, 4qaw:G, 4qaw:H, 4qb1:A, 4qb2:A, 4qb6:A
11 3kl0:A 397 370 0.1814 0.2065 0.2216 3.23e-04 3kl3:A, 3kl3:B, 3kl5:A, 3kl5:B, 3kl5:C
12 8cbc:A 455 218 0.1084 0.1077 0.2248 7.12e-04 8c48:A, 8c48:B, 8cbc:B, 7o0e:A, 7o0e:G, 8p67:A, 8p67:B
13 8cbc:A 455 59 0.0398 0.0396 0.3051 0.017 8c48:A, 8c48:B, 8cbc:B, 7o0e:A, 7o0e:G, 8p67:A, 8p67:B
14 5nxb:A 644 113 0.0619 0.0435 0.2478 0.23 4ccc:A, 4ccd:A, 4cce:A, 5nxb:B, 4ufh:A, 4ufi:A, 4ufj:A, 4ufk:A, 4ufl:A, 4ufm:A, 6y6s:A, 6y6t:A, 3zr5:A, 3zr6:A
15 8je1:A 675 44 0.0420 0.0281 0.4318 0.54
16 7dm1:B 334 55 0.0487 0.0659 0.4000 0.59 7dm1:A, 7dm2:A, 1pc3:A, 1pc3:B
17 7l08:AX 353 73 0.0509 0.0652 0.3151 1.0 8any:AX, 8csp:X, 8csq:X, 8csr:X, 8css:X, 8cst:X, 8csu:X, 8k2a:Se, 7og4:AX, 8oir:AX, 8ois:AX, 7p2e:X, 7pnx:X, 7pny:X, 7pnz:X, 7po0:X, 7po1:X, 7po2:X, 7po3:X, 7qi4:AX, 7qi5:AX, 7qi6:AX, 8qrk:X, 8qrl:X, 8qrm:X, 8qrn:X, 6rw4:X, 6rw5:X, 6vlz:AX, 6vmi:AX, 8xt0:Se, 8xt2:Se, 6zm5:AX, 6zm6:AX, 6zs9:AX, 6zsa:AX, 6zsb:AX, 6zsc:AX, 6zsd:AX, 6zse:AX, 6zsg:AX
18 7a5f:X6 316 73 0.0509 0.0728 0.3151 1.2 7a5g:X6, 7a5i:X6, 7a5k:X6, 3j9m:AX, 6nu2:AX, 6nu3:AX
19 1vl0:A 281 44 0.0310 0.0498 0.3182 1.7 1vl0:B, 1vl0:C
20 6gaw:Ag 353 73 0.0509 0.0652 0.3151 2.3 5aj3:g, 5aj4:Ag, 6gaz:Ag, 3jd5:g, 6neq:g, 6nf8:g, 7nqh:Ag, 7nql:Ag, 7nsi:Ag, 7nsj:Ag, 8oin:AX, 8oip:AX, 6ydp:Ag, 6ydw:Ag
21 6mf5:B 262 87 0.0442 0.0763 0.2299 4.3 6mf4:A, 6mf5:A, 6mf6:B, 6mf6:A
22 6b2e:B 193 44 0.0376 0.0881 0.3864 4.3 4cfh:B, 4rer:B, 4yee:A, 4yee:G, 4yee:B, 4yee:C, 4yee:D, 4yee:N, 4yee:E, 4yee:F, 4yee:H, 4yee:I, 4yee:J, 4yee:K, 4yee:L, 4yee:M, 4yee:O, 4yee:P, 4yee:Q, 4yee:R
23 8vz8:A 266 34 0.0265 0.0451 0.3529 5.8 8vz9:A
24 7ezi:A 323 305 0.1372 0.1920 0.2033 6.4 7ezl:A
25 4pfb:A 308 56 0.0442 0.0649 0.3571 7.7
26 5a79:A 177 31 0.0288 0.0734 0.4194 7.8 5a7a:A
27 3fz6:E 464 46 0.0332 0.0323 0.3261 8.2 2dgk:A, 2dgk:B, 2dgk:C, 2dgk:D, 2dgk:E, 2dgk:F, 2dgl:A, 2dgl:B, 2dgl:C, 2dgl:D, 2dgl:E, 2dgl:F, 2dgm:A, 2dgm:B, 2dgm:C, 2dgm:D, 2dgm:E, 2dgm:F, 3fz6:A, 3fz6:B, 3fz6:C, 3fz6:D, 3fz6:F, 3fz8:A, 3fz8:B, 3fz8:C, 3fz8:D, 3fz8:E, 3fz8:F, 1pmm:A, 1pmm:B, 1pmm:C, 1pmm:D, 1pmm:E, 1pmm:F, 1pmo:A, 1pmo:B, 1pmo:C, 1pmo:D, 1pmo:E, 1pmo:F, 1xey:A, 1xey:B
28 4yd9:B 825 152 0.0796 0.0436 0.2368 8.5 4yd9:E, 4yd9:H, 4yd9:K, 4yd9:N, 4yd9:Q, 4yd9:T, 4yd9:W, 4yd9:Z, 4yd9:c

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218