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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GDEYAEDSSDEEDIRNTVGNVPLEWYDDFPHVGYDLDGRRIYKPPDYWRTVQDPMTGRDLRLTDEQVALVRRLQSGQFGD
VGFNPYEPAVDFFSGDVMIHPVTNRPADKRSFIPSLVEKEKVSRMVHAIKMGWIQPRRPRDPTPSFYDLWARHKMHVPAP
KLALPGHAESYNPPPEYLLSEEERLAWEQQEPGERKLSFLPRKFPSLRAVPAYGRFIQERFERCLDLYLCPRQRK

The query sequence (length=235) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8fkp:SS 235 235 1.0000 1.0000 1.0000 4.13e-176 8fkq:SS, 8fkr:SS, 8fks:SS
2 8fky:SS 628 260 1.0000 0.3742 0.9038 4.07e-165 8fkt:SS, 8fku:SS, 8fkv:SS, 8fkw:SS, 8fkx:SS
3 7nac:m 666 256 0.4723 0.1667 0.4336 2.80e-60 8e5t:s, 6em1:m, 6em3:B, 7nad:m, 7ohp:m, 7ohs:m, 7ohw:m, 7ohx:m, 7r6q:m, 7r72:m, 7r7a:m, 8v87:m
4 8i9x:CC 658 255 0.4553 0.1626 0.4196 4.46e-60 8i9r:CC, 8i9t:CC, 8i9v:CC, 8i9w:CC, 8i9y:CC, 8i9z:CC, 8ia0:CC, 8pv2:CC
5 6elz:m 645 260 0.4723 0.1721 0.4269 2.71e-59 6em5:m, 7ohr:m, 7ohv:m
6 8i9p:CC 258 239 0.4213 0.3837 0.4142 1.44e-57
7 8v83:m 211 236 0.4085 0.4550 0.4068 1.14e-48 8v84:m
8 8esq:m 572 254 0.3660 0.1503 0.3386 1.15e-31 8esr:m, 8etg:m, 8eti:m, 8eug:m, 8eui:m
9 8euy:m 92 55 0.0851 0.2174 0.3636 4.19e-05
10 6cb1:s 512 52 0.0936 0.0430 0.4231 5.30e-05 6c0f:s
11 6cb1:s 512 24 0.0723 0.0332 0.7083 0.003 6c0f:s
12 8eth:m 76 52 0.0809 0.2500 0.3654 5.59e-05 8eup:m, 8ev3:m
13 8ev3:4 211 66 0.0809 0.0900 0.2879 0.20 8eti:4
14 8gqd:E 59 23 0.0468 0.1864 0.4783 0.81
15 6ldv:L 214 44 0.0596 0.0654 0.3182 1.1 6ldx:L
16 8jow:A 227 60 0.0638 0.0661 0.2500 2.1 8jow:C
17 5z20:F 336 38 0.0638 0.0446 0.3947 2.1 5z20:A, 5z20:B, 5z20:C, 5z20:D, 5z20:E
18 3dwc:B 504 75 0.0809 0.0377 0.2533 2.5 3dwc:A, 3dwc:C, 3dwc:D
19 6ldy:B 216 58 0.0723 0.0787 0.2931 4.4 6ldy:L
20 8bdb:L 138 44 0.0596 0.1014 0.3182 7.2 8bdb:N
21 6ty4:A 621 77 0.0979 0.0370 0.2987 7.2 4brx:A, 3bz3:A, 4c7t:A, 4d4s:B, 4d4v:B, 4d58:B, 4d5h:A, 4ebv:A, 4ebw:A, 2etm:A, 2etm:B, 6gcr:A, 6gcw:A, 6gcw:B, 6gcx:A, 4gu6:A, 4gu6:B, 4gu9:B, 4i4e:A, 4i4f:A, 6i8z:A, 2ijm:A, 2ijm:B, 2j0j:A, 2j0k:B, 2j0l:A, 2j0m:B, 2jkk:A, 2jkm:A, 2jko:A, 2jkq:A, 4k8a:A, 4k8a:B, 4k9y:A, 4kab:B, 4kao:B, 7pi4:DDD, 3pxk:A, 3pxk:B, 6ty4:B, 6yoj:A, 6yq1:A, 6yq1:B, 6yq1:C, 6yq1:D, 6yr9:A, 6yr9:B, 6yr9:C, 6yr9:D, 6yt6:A, 6yt6:B, 6yvs:A, 6yvs:B, 6yvs:C, 6yvs:D, 6yvy:A, 6yvy:B, 6yvy:C, 6yvy:D, 6yxv:A, 6yxv:B, 6yxv:C, 6yxv:D
22 7yk5:J 139 44 0.0553 0.0935 0.2955 8.4 7yk5:N, 7yk5:L, 7yk5:P

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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