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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GCPDGWTQFLDLCYIYQSAKASWASAQSSCQALGGILAEPDTACENEVLIHMCKENGDAGSFGPWLGGQKVGGAWQWSSS
GAAFDYLRWGPNEPNNSGGNEDCLHYNWLSWNDLRCHYQASYLCQRAAE

The query sequence (length=129) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2vuv:A 129 129 1.0000 1.0000 1.0000 1.55e-93 2vuz:A
2 1tdq:B 126 131 0.2946 0.3016 0.2901 2.66e-13
3 1sl6:A 168 129 0.3178 0.2440 0.3178 4.93e-12 1k9j:A, 1sl6:B, 1sl6:C, 1sl6:D, 1sl6:E, 1sl6:F, 1xph:A
4 4zes:A 147 132 0.3101 0.2721 0.3030 1.45e-11 4zes:B, 4zet:A, 4zet:B
5 3whd:C 148 131 0.3178 0.2770 0.3130 2.33e-11 3whd:A
6 3wh2:A 132 132 0.3023 0.2955 0.2955 6.32e-11 3wh3:A
7 4c9f:D 134 131 0.2713 0.2612 0.2672 3.01e-10 4c9f:A, 4c9f:B, 4c9f:C, 4caj:A, 4caj:B, 4caj:C, 4caj:D, 3zhg:A, 3zhg:B, 3zhg:C, 3zhg:D
8 6ghv:D 133 131 0.2713 0.2632 0.2672 4.15e-10 6ghv:A, 6ghv:B, 6ghv:C, 6ghv:E, 6ghv:F, 2it5:A, 2it6:A, 1k9i:A, 1k9i:C, 1k9i:D, 1k9i:E, 1k9i:H, 1k9i:B, 1k9i:F, 1k9i:G, 1k9i:I, 1k9i:J, 7nl6:A, 7nl7:A, 1sl4:A, 1sl5:A, 2xr5:A, 2xr6:A
9 2ric:C 158 104 0.2481 0.2025 0.3077 5.14e-10 1b08:A, 1b08:B, 1b08:C, 3dbz:A, 3dbz:B, 3dbz:C, 4e52:B, 4e52:C, 4e52:A, 3g81:A, 3g81:B, 3g81:C, 3g83:A, 3g83:B, 3g83:C, 3g84:A, 3g84:B, 3g84:C, 2ggu:A, 2ggu:B, 2ggu:C, 2ggx:A, 2ggx:B, 2ggx:C, 3ikn:A, 3ikn:B, 3ikn:C, 3ikp:A, 3ikp:B, 3ikp:C, 3ikq:A, 3ikq:B, 3ikq:C, 3ikr:A, 3ikr:B, 3ikr:C, 4m17:A, 4m17:B, 4m17:C, 4m17:D, 4m17:E, 4m17:F, 4m17:G, 4m17:H, 4m17:I, 4m17:J, 4m17:K, 4m17:L, 4m18:A, 4m18:E, 4m18:B, 4m18:C, 4m18:D, 4m18:L, 4m18:F, 4m18:G, 4m18:H, 4m18:I, 4m18:J, 4m18:K, 2orj:A, 2orj:B, 2orj:C, 2ork:A, 2ork:B, 2ork:C, 2os9:A, 2os9:B, 2os9:C, 5oxr:B, 5oxr:C, 5oxr:A, 5oxs:A, 5oxs:B, 5oxs:C, 1pw9:A, 1pw9:B, 1pw9:C, 1pwb:A, 1pwb:B, 1pwb:C, 2ria:A, 2ria:B, 2ria:C, 2rib:A, 2rib:B, 2rib:C, 2ric:B, 2ric:A, 2rid:A, 2rid:B, 2rid:C, 2rie:A, 2rie:B, 2rie:C
10 8h4v:A 148 130 0.2868 0.2500 0.2846 5.32e-10 8h4v:B, 8hb5:A, 5kth:A, 5kti:A, 4kzv:A, 4kzv:B, 4kzw:A, 4kzw:B, 4zrv:A, 4zrv:C, 4zrv:B, 4zrw:A
11 2py2:A 127 130 0.2946 0.2992 0.2923 1.51e-09 2py2:B, 2py2:C, 2py2:D, 2py2:E, 2py2:F
12 4gko:L 136 131 0.2791 0.2647 0.2748 1.69e-09 4g9a:A, 4g9a:B, 4g9a:C, 4g9a:D, 4gko:G, 4gko:H, 4gko:I, 4gko:J, 4gko:K, 2h2t:B
13 4yli:D 155 114 0.2481 0.2065 0.2807 1.95e-09 4yli:A, 4yli:B, 4yli:C, 4yli:E, 4yli:F, 4ymd:A, 4ymd:B, 4ymd:D, 4ymd:F, 4ymd:C, 4ymd:E
14 6py1:A 130 131 0.2868 0.2846 0.2824 2.12e-09 6puv:A, 6w12:A, 6xiy:A
15 6pwr:A 129 131 0.2868 0.2868 0.2824 4.35e-09 6pws:A, 6pwt:A
16 1qdd:A 144 131 0.2791 0.2500 0.2748 2.39e-08
17 3kqg:A 169 131 0.3023 0.2308 0.2977 4.05e-08 4ak8:A, 4ak8:B, 4ak8:C, 4ak8:D, 3c22:A, 3c22:B, 3c22:C, 3c22:D, 5g6u:A, 5g6u:B, 5g6u:D, 5g6u:C, 3kqg:B, 3kqg:C, 3kqg:D, 3kqg:E, 3kqg:F, 4n32:A, 4n32:B, 4n32:C, 4n32:D, 4n33:A, 4n33:B, 4n33:C, 4n33:D, 4n34:A, 4n34:B, 4n34:C, 4n34:D, 4n35:A, 4n35:B, 4n35:C, 4n35:D, 4n36:A, 4n36:B, 4n36:C, 4n36:D, 4n37:A, 4n37:B, 4n37:C, 4n37:D, 4n38:A, 4n38:B, 4n38:C, 4n38:D, 3p5d:A, 3p5d:B, 3p5d:C, 3p5d:D, 3p5e:A, 3p5e:B, 3p5e:C, 3p5e:D, 3p5f:B, 3p5f:C, 3p5f:A, 3p5f:D, 3p5g:A, 3p5g:B, 3p5g:C, 3p5g:D, 3p5h:B, 3p5h:D, 3p5h:A, 3p5h:C, 3p5i:A, 3p5i:B, 3p5i:C, 3p5i:D, 3p7f:A, 3p7f:B, 3p7f:C, 3p7f:D, 3p7g:A, 3p7g:B, 3p7g:C, 3p7g:D, 3p7h:A, 3p7h:B, 3p7h:C, 3p7h:D, 7ytq:A, 7ytq:B, 7ytq:C, 7ytq:D
18 6jk4:A 126 131 0.2946 0.3016 0.2901 4.34e-08
19 8urf:A 128 132 0.2481 0.2500 0.2424 7.28e-08
20 6a7s:B 138 112 0.2093 0.1957 0.2411 1.29e-07 6a7t:B, 6m5m:B
21 1egg:B 144 136 0.2946 0.2639 0.2794 1.47e-07 1egg:A, 1egi:A, 1egi:B, 7jub:A, 7juc:A, 7jud:A, 7jud:B, 7jue:A, 7juf:A, 7juf:B, 7jug:A, 7juh:A, 7l61:A, 7l62:A, 7l63:A, 7l64:A, 7l65:A, 7l66:A, 7l67:A, 7l68:A, 7l68:B
22 5e4k:A 424 129 0.2868 0.0873 0.2868 1.57e-07
23 6ryj:A 122 117 0.2558 0.2705 0.2821 1.61e-07 6ryg:A, 6rym:A, 6ryn:A
24 5jq1:A 130 132 0.2558 0.2538 0.2500 1.81e-07 1dv8:A, 5jpv:A, 5jpv:B, 5jq1:B, 8ts0:A, 6yau:A
25 6jjj:A 151 133 0.2868 0.2450 0.2782 2.20e-07 6jjj:B, 6jjj:C, 6jjj:D, 6jjj:E, 6jjj:F
26 3cfw:A 156 123 0.2558 0.2115 0.2683 3.55e-07 5vc1:A
27 6bbe:A 155 110 0.2403 0.2000 0.2818 5.02e-07 6bbd:A, 4dn8:A
28 5vyb:A 143 132 0.2713 0.2448 0.2652 9.44e-07
29 2ox9:C 131 135 0.2558 0.2519 0.2444 9.83e-07 2ox9:A, 2ox9:B, 2ox9:D
30 5k8y:A 136 130 0.2791 0.2647 0.2769 1.08e-06 5k8y:B, 5m62:A, 5m62:B
31 2ox8:A 129 132 0.2558 0.2558 0.2500 1.30e-06 2ox8:B, 2ox8:C, 2ox8:D
32 1hup:A 141 113 0.2248 0.2057 0.2566 3.07e-06
33 5f2q:B 135 133 0.2636 0.2519 0.2556 5.46e-06 5f2q:A, 5f2q:C, 5f2q:D, 5f2q:E, 5f2q:F, 5f2q:G, 5f2q:H, 5f2q:I, 5f2q:J, 1jzn:A, 1jzn:B, 1jzn:C, 1jzn:D, 1jzn:E, 1muq:B, 1muq:A, 1muq:C, 1muq:D, 1muq:E
34 1bj3:A 129 129 0.2636 0.2636 0.2636 7.56e-06 1j34:A, 1j35:A, 1x2t:A, 1x2t:C
35 1g1q:A 160 123 0.2713 0.2188 0.2846 1.08e-05 1g1q:B, 1g1q:C, 1g1q:D, 1g1r:A, 1g1r:B, 1g1r:D, 1g1r:C, 1g1s:B, 1g1s:A
36 5b1w:A 130 132 0.2481 0.2462 0.2424 1.08e-05 5b1w:B, 5b1w:C, 5b1w:D, 5b1x:A, 5b1x:B, 5b1x:C, 5b1x:D
37 4c16:A 280 79 0.2016 0.0929 0.3291 1.49e-05 4c16:B, 4csy:A, 4csy:B, 1esl:A, 6eyi:A, 6eyj:A, 6eyj:B, 6eyk:A, 1g1t:A
38 3vyk:A 128 136 0.3023 0.3047 0.2868 1.60e-05
39 4mth:A 139 135 0.2713 0.2518 0.2593 2.01e-05 1uv0:A
40 1kza:1 115 113 0.2171 0.2435 0.2478 3.09e-05 1kza:2, 1kzb:1, 1kzb:2, 1kzc:1, 1kzc:2, 1kzd:1, 1kzd:2, 1kze:1, 1kze:2, 1rdi:1, 1rdi:2, 1rdj:1, 1rdj:2, 1rdk:1, 1rdk:2, 1rdl:1, 1rdl:2, 1rdm:1, 1rdm:2, 1rdn:1, 1rdn:2, 1rdo:1, 1rdo:2
41 6a7t:A 137 112 0.1938 0.1825 0.2232 3.89e-05 6m5m:A
42 1htn:A 156 121 0.2481 0.2051 0.2645 6.58e-05 1tn3:A
43 1iod:A 129 129 0.2248 0.2248 0.2248 9.18e-05 1wt9:A, 1y17:A
44 6lfj:A 133 132 0.2558 0.2481 0.2500 9.86e-05 6kzr:A, 6kzr:B, 6lfj:B, 6lkr:A, 6lkr:B
45 1iod:B 123 133 0.2481 0.2602 0.2406 9.87e-05 1wt9:B, 1y17:B
46 1ixx:A 129 129 0.2326 0.2326 0.2326 1.03e-04 1ixx:C, 1ixx:E
47 4wqq:A 141 139 0.2713 0.2482 0.2518 2.20e-04 1wmy:A, 1wmy:B, 1wmz:A, 1wmz:B, 1wmz:C, 1wmz:D, 4wqq:B, 4wqq:C, 4wqq:D
48 5e4l:A 428 116 0.2481 0.0748 0.2759 5.48e-04
49 3pak:A 145 106 0.2016 0.1793 0.2453 0.001 5ffr:A, 5ffs:A, 5fft:A, 3paq:A, 3par:A, 3pbf:A, 1r13:A, 1r14:A, 4wr9:A, 4wrc:A, 4wre:A, 4wrf:A, 4wuw:A, 4wux:A
50 5xts:A 460 117 0.2326 0.0652 0.2564 0.003 5xtw:A, 5xtw:C, 5xtw:D, 5xtw:E, 5xtw:F, 5xtw:H
51 7odu:A 129 80 0.1628 0.1628 0.2625 0.003
52 3vpp:B 122 78 0.1550 0.1639 0.2564 0.012 3vpp:A
53 1bj3:B 123 133 0.2481 0.2602 0.2406 0.013 1ixx:B, 1ixx:D, 1ixx:F, 1j34:B, 1j35:B, 1x2t:B, 1x2t:D
54 3alu:A 157 144 0.2791 0.2293 0.2500 0.032 3als:A, 3als:B, 3als:C, 3als:D, 3alt:A, 3alt:B, 3alt:C, 3alt:D, 3alu:B, 3alu:C, 3alu:D
55 3wsr:A 120 133 0.2171 0.2333 0.2105 0.050 3wsr:B
56 6tl9:F 130 76 0.1240 0.1231 0.2105 0.063 6tl9:B, 6tl9:C, 6tl9:G
57 2bpe:A 128 107 0.2093 0.2109 0.2523 0.12 2bpe:B, 2bph:A, 2bph:B, 2cl8:A, 2cl8:B
58 1ukm:B 124 90 0.1938 0.2016 0.2778 0.12
59 8ea6:B 124 78 0.1473 0.1532 0.2436 0.25 8ea5:A, 8ea5:B, 8ea6:A, 8ea7:A, 8ea7:B, 8ea8:B, 8ea8:A, 8ea9:B, 8ea9:A, 8eaa:B, 8eaa:A, 8eab:A, 8eab:B, 8se5:B, 8se5:A, 8se6:A, 8se6:B
60 3j82:A 131 129 0.2326 0.2290 0.2326 0.39
61 1oao:C 729 47 0.1240 0.0219 0.3404 0.96 3git:A, 3git:B, 3git:C, 3git:D, 3git:E, 3git:F, 3i01:M, 3i01:N, 3i01:O, 3i01:P, 3i04:M, 3i04:N, 3i04:O, 3i04:P, 1mjg:M, 1mjg:N, 1mjg:O, 1mjg:P, 1oao:D, 6x5k:M, 6x5k:N, 6x5k:O, 6x5k:P, 2z8y:M, 2z8y:N, 2z8y:O, 2z8y:P
62 8ulg:B 824 19 0.0775 0.0121 0.5263 1.1 7jsn:B, 6mzb:B, 8ufi:B, 8ugb:B, 8ugs:B
63 5e4l:B 386 80 0.1783 0.0596 0.2875 1.1
64 8cja:B 731 47 0.1240 0.0219 0.3404 1.6 8cjb:B, 8cjc:B, 8cmw:B, 7nyp:A, 7nyp:B, 7nys:A, 7nys:B, 7nz5:A, 7nz5:B, 7o0d:A, 1ru3:A, 7zkj:B, 7zkk:B, 7zkv:B
65 1byf:A 123 127 0.2093 0.2195 0.2126 4.3 1byf:B, 1tlg:A, 1tlg:B
66 6o3v:B 831 25 0.0930 0.0144 0.4800 5.6 6o3v:A, 6o3v:C, 6o6b:A, 6o6b:B, 6o6b:C, 6o6b:D
67 8arv:A 255 46 0.1085 0.0549 0.3043 6.6 8arv:B
68 4rh7:A 3005 47 0.1318 0.0057 0.3617 7.9
69 6sc2:B 3930 47 0.1318 0.0043 0.3617 8.2 6rla:A, 6rla:B, 6sc2:A
70 4jed:A 212 30 0.0775 0.0472 0.3333 9.4
71 3t3a:A 122 99 0.1860 0.1967 0.2424 9.7 3t3a:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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