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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
GAYVLDDSDGLGREFDGIGAVSGGGATSRLLVNYPEPYRSEILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYE
LDENYFRGYEWWLMKEAKKRNPDIILMGLPWSFPGWLGKGFSWPYVNLQLTAYYVVRWILGAKHYHDLDIDYIGIWNERP
FDANYIKELRKMLDYQGLQRVRIIASDNLWEPISSSLLLDQELWKVVDVIGAHYPGTYTVWNAKMSGKKLWSSEDFSTIN
SNVGAGCWSRILNQNYINGNMTSTIAWNLVASYYEELPYGRSGLMTAQEPWSGHYVVASPIWVSAHTTQFTQPGWYYLKT
VGHLEKGGSYVALTDGLGNLTIIIETMSHQHSMCIRPYLPYYNVSHQLATFTLKGSLREIQELQVWYTKLGQRLHFKQLD
TLWLLDGSGSFTLELEEDEIFTLTTLTTGRKGSYPPPPSSKPFPTNYKDDFNVEYPLFSEAPNFADQTGVFEYYMNNEDR
EHRFTLRQVLNQRPITWAADASSTISVIGDHHWTNMTVQCDVYIETPRSGGVFIAGRVNKGGILIRSATGVFFWIFANGS
YRVTADLGGWITYASGHADVTAKRWYTLTLGIKGYFAFGMLNGTILWKNVRVKYPGHGWAAIGTHTFEFAQFDNFRVEAA
R

The query sequence (length=641) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5nxb:A 644 644 1.0000 0.9953 0.9953 0.0 4ccc:A, 4ccd:A, 4cce:A, 5nxb:B, 4ufh:A, 4ufi:A, 4ufj:A, 4ufk:A, 4ufl:A, 4ufm:A, 6y6s:A, 6y6t:A, 3zr5:A, 3zr6:A
2 4uqa:A 391 161 0.0624 0.1023 0.2484 1.49e-05 5a6l:A, 5a6m:A, 4ckq:A, 4uqc:A
3 4qaw:A 537 268 0.0874 0.1043 0.2090 0.001 4qaw:B, 4qaw:C, 4qaw:D, 4qaw:E, 4qaw:F, 4qaw:G, 4qaw:H, 4qb1:A, 4qb2:A, 4qb6:A
4 8idp:A 446 145 0.0624 0.0897 0.2759 0.033 8idp:C, 8idp:B, 8idp:D, 8idq:A, 8idq:B, 8idq:C, 8idq:D
5 5te4:G 341 120 0.0484 0.0909 0.2583 0.077
6 3kl0:A 397 189 0.0624 0.1008 0.2116 0.080 3kl3:A, 3kl3:B, 3kl5:A, 3kl5:B, 3kl5:C
7 6m5z:A 433 185 0.0764 0.1132 0.2649 0.24 6m5z:B
8 5ngl:B 454 113 0.0437 0.0617 0.2478 0.35 5ngl:A, 5ngl:C
9 8xkf:C 377 62 0.0296 0.0504 0.3065 2.5 8xhu:A, 8xhu:B, 8xhu:C, 8xkf:A, 8xkf:B, 8xkf:D, 8xkf:F, 8xkf:E
10 2fc6:A 50 45 0.0218 0.2800 0.3111 3.0
11 6pdt:A 500 91 0.0343 0.0440 0.2418 3.7 6pdt:B, 6pdt:C, 6pdt:D
12 6vs7:A 409 52 0.0250 0.0391 0.3077 3.8 6vs7:E, 6vt2:A, 6vt2:E, 6vu6:A, 6vu6:E
13 3eld:A 277 61 0.0281 0.0650 0.2951 5.8 3elu:A, 3elw:A, 3ely:A, 3emb:A, 3emd:A
14 5hkj:A 402 62 0.0281 0.0448 0.2903 7.7 5hzf:A, 2jg8:B, 2jg8:C, 2jg8:D, 2jg8:E, 2jg9:B, 2jg9:E, 1pk6:B, 2wnu:F, 2wnv:B, 2wnv:C, 2wnv:D, 2wnv:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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