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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
FQSMNRSALDFRHFVDHLRRQGDLVDVHTEVDANLEIGAITRRVYERRAPAPLFHNIRDSLPGARVLGAPAGLRADRARA
HSRLALHFGLPEHSGPRDIVAMLRAAMRAEPIAPRRLERGPVQENVWLGEQVDLTRFPVPLLHEQDGGRYFGTYGFHVVQ
TPDGSWDSWSVGRLMLVDRNTLAGPTIPTQHIGIIREQWRRLGKPTPWAMALGAPPAALAAAGMPLPEGVSEAGYVGALV
GEPVEVVRTQTNGLWVPANTEIVLEGEISLDETALEGPMGEYHGYSFPIGKPQPLFHVHALSFRDQPILPICVAGTPPEE
HHTIWGTMISAQLLDVAQNAGLPVDMVWCSYEAATCWAVLSIDVQRLAALGTDAAAFAARVAETVFGSHAGHLVPKLILV
GNDIDVTEIDQVVWALATRAHPLHDHFAFPQIRDFPMVPYLDAEDKARGSGGRLVINCLYPEQFAGQMRAATASFRHAYP
TALRRRVEERWSDYGFGDA

The query sequence (length=499) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4ip2:C 502 497 0.9940 0.9880 0.9980 0.0 7abn:D, 7abn:A, 7abn:H, 7abn:M, 7abo:C, 7abo:B, 7abo:D, 7abo:A, 4ip2:A, 4ip2:B
2 7ney:A 497 491 0.4108 0.4125 0.4175 1.17e-136 7ney:B, 7nf0:A, 7nf0:B, 7nf1:A, 7nf1:B, 7nf2:A, 7nf2:B
3 6evf:A 503 496 0.3868 0.3837 0.3891 6.18e-135 6eve:A, 6eve:B, 6eve:C, 6eve:D, 6evf:B, 6evf:C, 6evf:D, 4s13:C, 4s13:F, 4zac:A, 4zac:B, 4zac:C, 4zac:D
4 7nf4:A 504 496 0.4028 0.3988 0.4052 2.01e-134 8crd:A, 6ev3:A, 6ev4:A, 6ev5:A, 6ev6:A, 6ev7:A, 6ev8:A, 6ev9:A, 6eva:A, 6evb:A, 6evc:A, 6evd:A, 7nf3:A, 7nf4:B, 8oed:A, 8oeh:A, 8oeo:A, 6r2p:A, 6r2r:A, 6r2t:A, 6r2z:A, 6r30:A, 6r32:A, 6r33:A, 6r34:A, 6r3f:A, 6r3g:A, 6r3i:A, 6r3j:A, 6r3l:A, 6r3n:A, 6r3o:A, 6tib:AAA, 6tic:AAA, 6tie:AAA, 6tih:AAA, 6tij:AAA, 6til:AAA, 6tin:AAA, 6tio:AAA, 4za4:A, 4za5:A, 4za7:A, 4za8:A, 4za9:A, 4zaa:A, 4zab:A
5 4zad:A 511 508 0.3788 0.3699 0.3720 1.80e-117 4zad:B
6 4s13:A 472 494 0.3607 0.3814 0.3644 2.33e-117 4s13:G
7 6da9:A 463 490 0.3527 0.3801 0.3592 1.10e-94
8 7pda:A 477 429 0.2826 0.2956 0.3287 1.42e-43
9 5m1d:A 469 459 0.2665 0.2836 0.2898 7.66e-38 5m1d:B, 5m1d:C, 5m1e:A, 5m1e:B, 5m1e:C
10 7ae4:A 476 463 0.2445 0.2563 0.2635 2.42e-26 7ae4:B, 7ae4:C, 7ae4:D, 7ae4:E, 7ae4:F
11 5o3n:A 488 503 0.2605 0.2664 0.2584 3.16e-26 5o3n:B
12 6h6v:F 446 419 0.2285 0.2556 0.2721 4.56e-26 6h6v:A, 6h6v:B, 6h6v:C, 6h6v:D, 6h6v:E, 6h6x:B, 6h6x:A
13 5o3m:A 493 470 0.2445 0.2475 0.2596 1.27e-21 5o3m:B, 5o3m:C, 5o3m:D, 5o3m:E, 5o3m:F
14 7p9q:A 454 421 0.2144 0.2357 0.2542 1.71e-18 7p9q:B, 7p9q:C, 7p9q:D, 7p9q:E, 7p9q:F
15 8oz5:A 514 456 0.2224 0.2160 0.2434 3.77e-16 8oz5:B, 8oz5:C, 8oz5:D, 8oz5:E, 8oz5:F, 8p02:A, 8p02:B, 8p02:C, 8p02:D, 8p02:E, 8p02:F, 8pmk:A, 8pmk:B, 8pmk:C, 8pmk:D, 8pmk:E, 8pmk:F
16 7x0f:C 458 68 0.0521 0.0568 0.3824 0.46 7x0e:A, 7x0f:A, 7x0f:B, 7x0f:D, 7x17:A, 7x17:B, 7x17:C, 7x17:D
17 3mlr:H 226 48 0.0341 0.0752 0.3542 0.78 3mls:H, 3mls:I, 3mls:J, 3mls:K, 3mlt:H, 3mlt:B, 3mlu:H, 3mlv:H, 3mlv:N
18 8gqm:A 377 39 0.0301 0.0398 0.3846 2.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218