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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
FPSAVTIKSWVDKMQEDLVTLAKTASGVHQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEK
VQAAHQWREDFASNEVVYYNAKDDEPGSQRIKPVFIDDANFRRQVSYQHAAVHIPTDIYEGSTIVLNELNWTSALDDVFK
KNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRT
SVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANC
NKIIMLFTDGGEERAQEIFAKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPM
VLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFA
IDPNGYVLLHPNLQPKPIGVGIPTINSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRT
YTWTPVNGTDYSLALVLPTYSFYYIKAKIEETITQARYSETLKPDNFEESGYTFLAPRDYCSDLKPSDNNTEFLLNFNEF
IDRKTPNNPSCNTDLINRVLLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKR
SLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKRNSDVMDCVILDDGGFLLM
ANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAASKQSCITEQTQYFFDNDSKSFSGVLDCGNCSR
IFHVEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGPDPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSG

The query sequence (length=955) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8e56:F 973 973 0.9948 0.9764 0.9764 0.0 8e57:F, 8e58:F, 8eog:D, 8fd7:D, 5gjw:F, 6jp5:F, 6jpa:F, 6jpb:F, 7vfs:B, 7vfu:B, 7vfv:B, 7vfw:B, 7xlq:D, 7yg5:D
2 8x90:B 964 975 0.9738 0.9647 0.9538 0.0 8e59:D, 8e5a:D, 8e5b:D, 8epl:C, 8epm:C, 8fhs:D, 7mix:D, 7miy:D, 7uhf:D, 7uhg:D, 8we6:D, 8we7:D, 8we8:D, 8we9:D, 8wea:D, 8x91:B, 8x93:B
3 8if3:A 917 953 0.9403 0.9793 0.9423 0.0
4 6fpy:A 600 170 0.0429 0.0683 0.2412 0.001 6fpy:B
5 5ltx:A 243 99 0.0293 0.1152 0.2828 0.055 5ltx:B, 5t65:A, 5t65:B, 5t7m:A, 5t7m:B
6 5ave:A 252 138 0.0377 0.1429 0.2609 0.21 5avf:A, 5avf:B, 3c8c:A, 3c8c:B, 6iov:A, 6iov:B
7 5lt9:B 253 95 0.0262 0.0988 0.2632 0.34 5lt9:A, 5lto:A, 5lto:B
8 4f1j:A 200 154 0.0387 0.1850 0.2403 0.43 4f1j:B, 4f1k:A, 4f1k:B
9 6mni:A 258 45 0.0168 0.0620 0.3556 0.51 6mni:B
10 2os1:A 179 62 0.0188 0.1006 0.2903 1.2
11 8k82:CN 112 103 0.0293 0.2500 0.2718 1.2 6tb3:BW
12 6bxj:A 619 52 0.0209 0.0323 0.3846 1.5 3bn3:A, 3bqm:B, 3bqm:C, 3bqn:B, 3bqn:C, 6bxb:A, 6bxb:B, 6bxf:A, 6bxf:B, 6ckb:A, 6ckb:B, 1cqp:A, 1cqp:B, 3e2m:A, 3e2m:B, 3eob:I, 3eob:J, 3f74:C, 3f78:A, 3f78:B, 3f78:C, 3hi6:A, 3hi6:B, 2ica:A, 4ixd:A, 7kc3:C, 7kc5:A, 7kc5:C, 7kc6:C, 7kc6:A, 1lfa:A, 1lfa:B, 3m6f:A, 1mjn:A, 1mq8:B, 1mq8:D, 1mq9:A, 2o7n:A, 1rd4:A, 1rd4:B, 1rd4:C, 1rd4:D, 1t0p:A, 3tcx:B, 3tcx:D, 3tcx:F, 3tcx:H, 3tcx:J, 3tcx:L, 3tcx:N, 3tcx:P, 3tcx:R, 3tcx:T, 3tcx:V, 3tcx:X, 3tcx:Z, 3tcx:b, 1xdd:A, 1xdd:B, 1xdg:A, 1xdg:B, 1xuo:A, 1xuo:B, 1zoo:A, 1zoo:B, 1zop:A, 1zop:B
13 6rhv:C 170 126 0.0335 0.1882 0.2540 2.3
14 2bkl:B 677 141 0.0387 0.0547 0.2624 2.4 2bkl:A
15 3l8p:A 292 41 0.0157 0.0514 0.3659 3.1 6mwe:A, 6mwe:B, 2oo8:X, 2osc:A, 2p4i:A, 2p4i:B, 2wqb:A, 4x3j:A
16 6bkf:A 562 139 0.0346 0.0587 0.2374 4.8
17 7fd4:D 779 63 0.0251 0.0308 0.3810 5.0 7fd4:B, 7fd4:C, 7fd4:E, 7fd4:F, 7fd4:A, 7fd5:B, 7fd5:C, 7fd5:E, 7fd5:A, 7fd5:F, 7fd5:D, 7fid:D, 7fid:A, 7fid:B, 7fid:C, 7fid:E, 7fid:F, 7fie:B, 7fie:C, 7fie:D, 7fie:E, 7fie:A, 7fie:F, 7fiz:B, 7fiz:C, 7fiz:E, 7fiz:A, 7fiz:D, 7fiz:F, 8k3y:B, 8k3y:C, 8k3y:D, 8k3y:E, 6wqh:A, 6wqh:B, 6wqh:C, 6wqh:F, 6wqh:D, 6wqh:E, 4ypl:A, 4ypl:B, 4ypl:C, 4ypl:F, 4ypl:D, 4ypl:E, 4ypm:A, 7yph:B, 7yph:D, 7ypi:A, 7ypi:B, 7ypj:A, 7ypj:B, 7ypj:C, 7ypj:D, 7ypk:F, 7ypk:B, 7ypk:E, 7ypk:A, 7ypk:C, 7ypk:D, 7yuv:A, 7yuv:B, 7yuv:C, 7yuw:A, 7yuw:B, 7yuw:C, 7yuw:D, 7yux:A, 7yux:C, 7yux:E, 7yux:D, 7yux:B
18 6ior:A 241 44 0.0147 0.0581 0.3182 5.8 6iop:A, 6iop:B, 6ioq:A, 6ior:B, 6ior:C, 6ior:D, 6ios:A, 6iot:A, 6iot:B, 6iot:C, 6iot:D, 6iou:A, 6iou:B
19 5ydj:B 538 45 0.0157 0.0279 0.3333 5.9 6ary:A, 6ary:B
20 5uf8:D 160 27 0.0094 0.0563 0.3333 7.2
21 2k5u:A 181 55 0.0157 0.0829 0.2727 8.2 2ksq:A, 1mr3:F, 4q66:F, 4q66:L, 3tjz:A, 3tjz:D
22 5ltv:D 226 43 0.0147 0.0619 0.3256 9.2 5ltv:A, 5ltv:B, 5ltv:E
23 6bqw:A 275 118 0.0346 0.1200 0.2797 9.2 6bqw:B, 6bqw:C, 6bqw:D, 6bqw:E, 6bqw:F, 6bqw:G, 6bqw:H, 6bqw:I, 6f95:A, 6f95:B, 6f95:C, 6f95:D, 6f95:E
24 8hla:B 215 28 0.0136 0.0605 0.4643 9.3 8hh0:A, 8hh0:B, 8hla:K, 8hla:L, 8hla:C, 8hla:F, 8hla:A, 8hla:D, 8hla:E, 8hla:G, 8hla:H, 8hla:I, 8hla:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218