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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
FNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVLVGAPKANTSQPGVLQGGAVYLCPWGASPTQCTPIEFDSKGSRLL
ESSLSSSEGEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKEPLSDPVGTCYLSTDNFTRILEYAPCRSDFSWAAG
QGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEF
SGDDTEDFVAGVPKGNLTYGYVTILNGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQE
VGRVYVYLQHPAGIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSKPSQ
VLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPVV

The query sequence (length=452) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7nxd:A 905 452 0.9978 0.4983 0.9978 0.0 9ckv:A, 7nwl:A, 3vi3:A, 3vi3:C, 3vi4:C, 3vi4:A, 4wjk:A, 4wk0:A, 4wk2:A, 4wk4:A
2 4g1e:A 964 453 0.5420 0.2541 0.5408 3.84e-170 5ffg:A, 5ffo:A, 5ffo:E, 4g1m:A, 3ije:A, 1jv2:A, 1l5g:A, 1m1x:A, 6mk0:A, 4mmx:A, 4mmy:A, 4mmz:A, 6msl:A, 6msu:A, 6naj:A, 5nem:A, 5ner:A, 5net:A, 4o02:A, 6om1:A, 6om1:C, 6om1:E, 6om1:G, 6om2:A, 6om2:C, 8tcf:A, 8tcg:A, 1u8c:A, 6uja:A, 6ujb:A, 6ujc:A, 4um8:C, 4um8:A, 4um9:A, 4um9:C, 8vs6:A, 8vsd:A, 7y1t:A
3 8t2v:A 946 472 0.4535 0.2167 0.4343 1.03e-105 4cak:A, 3fcs:A, 3fcs:C, 3fcu:A, 3fcu:C, 3fcu:E, 8gcd:A, 8gce:A, 5hdb:A, 5hdb:C, 7l8p:A, 7l8p:C, 7la4:A, 3nid:A, 3nid:C, 3nif:A, 3nif:C, 3nig:A, 3nig:C, 8t2u:A, 3t3m:A, 3t3m:C, 3t3p:A, 3t3p:C, 7tct:A, 7tct:C, 7td8:A, 7td8:C, 7tho:A, 7tho:C, 7tmz:A, 7tmz:C, 7tpd:A, 7tpd:C, 1tye:A, 1tye:C, 1tye:E, 7u60:A, 7u60:C, 7u9f:A, 7u9f:C, 7u9v:A, 7u9v:C, 7ubr:A, 7ubr:C, 7ucy:A, 7ucy:C, 7udg:A, 7udg:C, 7udh:A, 7udh:C, 7ue0:A, 7ue0:C, 7ufh:A, 7ufh:C, 7uh8:A, 7uh8:C, 7uje:A, 7uje:C, 7ujk:A, 7ujk:C, 7uk9:A, 7uk9:C, 7uko:A, 7uko:C, 7ukp:A, 7ukp:C, 7ukt:A, 7ukt:C, 6v4p:A, 2vc2:A, 2vdk:A, 2vdl:A, 2vdm:A, 2vdn:A, 2vdo:A, 2vdp:A, 2vdq:A, 2vdr:A, 4z7n:A, 4z7n:C, 4z7o:A, 4z7o:C, 4z7q:A, 4z7q:C, 3zdx:A, 3zdx:C, 3zdy:A, 3zdy:C, 3zdz:A, 3zdz:C, 3ze0:A, 3ze0:C, 3ze1:A, 3ze1:C, 3ze2:A, 3ze2:C
4 4irz:A 592 470 0.3451 0.2635 0.3319 1.03e-64 3v4p:A, 3v4p:C, 3v4v:A, 3v4v:C
5 7ceb:A 553 478 0.3584 0.2929 0.3389 3.78e-54 7cec:A
6 7usl:A 856 466 0.2942 0.1554 0.2854 2.26e-25 7usm:A
7 3k6s:C 885 473 0.3142 0.1605 0.3002 2.69e-24 5es4:C, 5es4:E, 5es4:G, 3k6s:E, 3k6s:G, 3k71:A, 3k71:C, 3k71:E, 3k72:A, 3k72:C
8 4neh:A 1084 305 0.2257 0.0941 0.3344 2.12e-23 5es4:A, 3k6s:A, 3k71:G
9 4nen:A 1063 305 0.2257 0.0960 0.3344 2.33e-23
10 7p2d:A 751 296 0.2080 0.1252 0.3176 3.32e-22 7akk:D, 7akk:H, 1bho:1, 1bho:2, 1ido:A, 1jlm:A, 1m1u:A, 3q3g:G, 3q3g:E, 3q3g:I, 3q3g:L, 3qa3:G, 3qa3:E, 3qa3:I, 3qa3:L, 6rhw:C, 8voi:A, 4xw2:A
11 5e6u:A 583 292 0.2013 0.1561 0.3116 4.95e-22 5e6r:A, 5e6s:A, 5e6s:C, 5e6s:E
12 6uy4:A 354 175 0.0973 0.1243 0.2514 1.4
13 7wua:A 603 66 0.0398 0.0299 0.2727 2.2 7wua:B, 7wua:C, 7wua:D
14 7q41:A 369 65 0.0442 0.0542 0.3077 6.1 7q41:C, 7q41:E, 7q42:C, 7q42:A, 7q42:E, 7q43:A, 7q43:C, 7q43:E, 7q44:C, 7q44:A, 7q44:E, 7q45:A, 7q45:C, 7q45:E, 7q46:C, 7q46:E, 7q46:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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