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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EYVVAKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQSDVMIVAGTLTNKMAPALRKVYDQ
MPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQKKIKREKRLRIWYR

The query sequence (length=152) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8q0j:B 158 152 1.0000 0.9620 1.0000 1.46e-112 7ak5:B, 7ak6:B, 7b93:B, 8c2s:B, 8ca3:B, 8ca5:B, 7dgq:D, 7dgr:D, 7dgs:D, 7dgz:D, 7dh0:D, 7dkf:D2, 6g2j:B, 6g72:B, 5gpn:a, 5gup:I, 8iao:B, 8iap:B, 8ib4:B, 8ib5:B, 8ib9:B, 8iba:B, 8ibd:B, 8ibe:B, 8ic2:B, 8ic3:B, 5lc5:B, 5ldw:B, 5ldx:B, 5lnk:6, 5o31:B, 8olt:B, 8om1:B, 7psa:B, 8pw5:6, 8pw6:6, 8pw7:6, 8q0a:B, 8q0f:B, 8q0m:B, 8q0o:B, 8q0q:B, 8q1p:B, 8q1u:B, 8q1y:B, 8q25:B, 8q45:B, 8q46:B, 8q47:B, 8q48:B, 8q49:B, 8q4a:B, 6q9d:S7, 6qa9:S7, 6qbx:S7, 6qc2:S7, 6qc3:S7, 6qc4:S7, 6qc5:S7, 6qc6:S7, 6qc7:S7, 6qc8:S7, 6qc9:S7, 6qca:S7, 6qcf:S7, 7qsd:B, 7qsk:B, 7qsl:B, 7qsm:B, 7qsn:B, 7qso:B, 7r41:B, 7r42:B, 7r43:B, 7r44:B, 7r45:B, 7r46:B, 7r47:B, 7r48:B, 7r4c:B, 7r4d:B, 7r4f:B, 7r4g:B, 8rgp:6, 8rgq:6, 8rgr:6, 8rgt:6, 8ud1:1B, 8ueo:1B, 8uep:1B, 8ueq:1B, 8uer:1B, 8ues:1B, 8uet:1B, 8ueu:1B, 8uev:1B, 8uew:1B, 8uex:1B, 8uey:1B, 8uez:1B, 8ugh:1B, 8ugi:1B, 8ugj:1B, 8ugn:1B, 8ugn:5B, 8ugp:1B, 8ugr:1B, 8ugr:5B, 7v2c:C, 7v2d:C, 7v2e:C, 7v2f:C, 7v2h:C, 7v2k:C, 7v2r:C, 7v30:C, 7v31:C, 7v32:C, 7v33:C, 7v3m:C, 7vb7:C, 7vbn:C, 7vbz:C, 7vwj:C, 7vxp:C, 7vxu:C, 7vy8:C, 7vya:C, 7vyf:C, 7vyh:C, 7vyn:C, 7vz1:C, 7vzv:C, 7vzw:C, 7w00:C, 7w0h:C, 7w0r:C, 7w0y:C, 7w1o:C, 7w1p:C, 7w1t:C, 7w1u:C, 7w1v:C, 7w1z:C, 7w20:C, 7w2k:C, 7w2l:C, 7w2r:C, 7w2u:C, 7w2y:C, 7w31:C, 7w32:C, 7w35:C, 7w4c:C, 7w4d:C, 7w4e:C, 7w4f:C, 7w4g:C, 7w4j:C, 7w4k:C, 7w4l:C, 7w4m:C, 7w4n:C, 7w4q:C, 5xtb:C, 5xtd:C, 5xth:C, 5xti:C, 5xti:BC, 7zd6:6, 7zdh:6, 7zdj:6, 7zdm:6, 7zdp:6, 7zeb:6, 6zk9:6, 6zkc:6, 6zkd:6, 6zke:6, 6zkf:6, 6zkg:6, 6zkh:6, 6zki:6, 6zkj:6, 6zkk:6, 6zkl:6, 6zkm:6, 6zkn:6, 6zko:6, 6zkp:6, 6zkq:6, 6zkr:6, 6zks:6, 6zkt:6, 6zku:6, 6zkv:6, 6zr2:B, 6ztq:B
2 8b9z:B 182 152 0.8421 0.7033 0.8421 1.27e-100 8ba0:B, 8esw:S7, 8esz:S7
3 8e73:S7 158 151 0.8289 0.7975 0.8344 4.03e-97 7a23:E, 7a24:E, 7aqr:B, 7ar7:B, 7ar8:B, 7arb:B, 8bee:B, 8bpx:B, 8bq5:B, 8bq6:B, 6x89:S7
4 7zm7:K 182 152 0.7763 0.6484 0.7763 2.49e-93 6h8k:K, 7zmb:K, 7zmg:K
5 7o6y:K 177 152 0.7566 0.6497 0.7566 2.07e-92 6gcs:K, 7o71:K, 6rfq:K, 6rfr:K, 6rfs:K, 4wz7:K, 6y79:K, 6yj4:B
6 8qby:B 148 146 0.7697 0.7905 0.8014 3.35e-87
7 7arc:B 154 152 0.7895 0.7792 0.7895 6.93e-87 7ard:B
8 7tgh:S7 162 144 0.6579 0.6173 0.6944 3.45e-81 8b6f:AT, 8bqs:AT, 8gym:s7, 8gym:S7, 8gzu:s7, 8gzu:S7
9 8iuf:S7 201 142 0.6711 0.5075 0.7183 2.84e-76 8j9h:S7, 8j9i:S7, 8j9j:S7
10 7q5y:F 135 132 0.5526 0.6222 0.6364 2.72e-66 7q5y:L, 7q5y:R, 7q5y:X
11 6i0d:6 166 137 0.5329 0.4880 0.5912 5.50e-60 4hea:6, 4hea:G, 6i0d:G, 6i1p:6, 6i1p:G, 3i9v:6, 3i9v:F, 3ias:6, 3ias:F, 3ias:O, 3ias:X, 3m9s:6, 3m9s:F, 6q8o:6, 6q8o:G, 6q8w:6, 6q8w:G, 6q8x:6, 6q8x:G, 6y11:6, 6y11:G, 6ziy:6, 6zjl:6, 6zjn:6, 6zjy:6
12 8e9g:B 183 142 0.5066 0.4208 0.5423 4.74e-56 8e9h:B, 8e9i:B
13 6nbq:K 212 143 0.4934 0.3538 0.5245 1.41e-55 6hum:K, 6khi:K, 6khj:K, 6l7o:K, 6l7p:K, 6nbx:K, 6nby:K, 6tjv:K
14 7z7s:B 213 148 0.5066 0.3615 0.5203 2.98e-55 7nyr:B, 7nyu:B, 7nyv:B, 7p61:B, 7p62:B, 7p63:B, 7p64:B, 7p7c:B, 7p7j:B, 7p7k:B, 7p7l:B, 7p7m:B, 7z7r:B, 7z7t:B, 7z7v:B, 7z80:B, 7z83:B, 7z84:B
15 7p69:B 169 148 0.4671 0.4201 0.4797 2.94e-49 7nz1:B, 7p7e:B, 7zc5:B, 7zci:B
16 2fug:6 144 138 0.4539 0.4792 0.5000 6.28e-49 2fug:F, 2fug:O, 2fug:X, 3iam:6, 3iam:F, 2ybb:6
17 7wfg:K 167 143 0.4474 0.4072 0.4755 9.60e-48 7wg5:K
18 7awt:B 141 130 0.4474 0.4823 0.5231 1.43e-46
19 6u8y:J 177 154 0.3816 0.3277 0.3766 1.21e-34 6u8y:j
20 6cfw:J 143 115 0.3026 0.3217 0.4000 1.96e-32
21 7z0s:G 250 122 0.3355 0.2040 0.4180 1.41e-28 7z0t:G
22 6qgr:G 253 84 0.1382 0.0830 0.2500 1.22e-04 6qgt:G, 6qii:G
23 4omf:G 231 92 0.1579 0.1039 0.2609 0.002 4ci0:B, 3zfs:B
24 1l1e:A 272 124 0.2105 0.1176 0.2581 0.003 1l1e:B
25 8w7y:A 474 64 0.1250 0.0401 0.2969 0.008
26 7t2r:E 179 27 0.0921 0.0782 0.5185 0.062 7t2r:J, 7t30:E, 7t30:J
27 5xf9:C 178 89 0.1776 0.1517 0.3034 0.063 5xf9:G, 5xfa:C, 5xfa:G
28 1tpy:A 285 39 0.0921 0.0491 0.3590 0.38
29 5sup:B 383 28 0.0724 0.0287 0.3929 0.50 5sup:A, 5sup:C, 5suq:A, 5suq:C
30 7mgv:A 333 41 0.0921 0.0420 0.3415 0.76 7mgv:B
31 5jsh:A 283 124 0.1711 0.0919 0.2097 1.1 5jsk:A, 5jsu:A, 5jsy:A, 5jt1:A, 6rtp:A, 6ru9:A, 6ruc:A, 2wpn:A, 6z7r:A, 6z7r:C, 6z8j:A, 6z8j:C, 6z8m:A, 6z8o:A, 6z8o:C, 6z9g:A, 6z9g:C, 6z9g:E, 6z9g:G, 6z9o:A, 6za1:A, 3ze6:A, 3ze7:A, 3ze8:A, 3ze9:A, 3zea:A
32 5m5w:B 1183 22 0.0789 0.0101 0.5455 1.9 4c2m:B, 4c2m:Q, 4c3h:B, 4c3i:B, 4c3j:B, 5g5l:B, 6h67:B, 6h68:B, 6hko:B, 6hlq:B, 6hlr:B, 5m3f:B, 5m3m:B, 5m5x:B, 5m5y:B, 5m64:B, 5n5y:B, 5n5z:B, 5n60:B, 5n61:B, 5oa1:B, 6rqh:B, 6rql:B, 6rqt:B, 6rrd:B, 6rui:B, 6ruo:B, 6rwe:B, 6tps:B, 5w5y:B, 5w64:B, 5w65:B, 5w66:B, 4ym7:AB, 4ym7:BB, 4ym7:CB, 4ym7:DB, 4ym7:EB, 4ym7:FB
33 5lmx:B 1115 22 0.0789 0.0108 0.5455 2.0
34 6w2j:B 1364 46 0.0855 0.0095 0.2826 2.9
35 4kl8:S 279 110 0.1776 0.0968 0.2455 3.8 1cc1:S, 4kl8:T, 4kn9:S, 4kn9:T, 4ko1:S, 4ko1:T, 4ko2:S, 4ko2:T, 4ko3:S, 4ko3:T, 4ko4:S, 4ko4:T
36 5odc:E 298 26 0.0658 0.0336 0.3846 4.6 5odc:K, 5odh:E, 5odh:K, 5odi:E, 5odi:K, 5odq:E, 5odq:K, 5odr:E, 5odr:K
37 2vfa:B 205 84 0.1316 0.0976 0.2381 6.1 2vfa:A
38 3nzq:A 628 58 0.1184 0.0287 0.3103 6.3 3nzq:B
39 1e3d:A 262 70 0.1382 0.0802 0.3000 6.3 1e3d:C
40 8inh:B 454 60 0.1118 0.0374 0.2833 8.1 8inh:A
41 7q2d:A 286 94 0.1382 0.0734 0.2234 8.6 2fk8:A, 3ha3:A, 3ha5:A, 3ha7:A, 7q2b:A, 7q2c:A, 7q2e:A, 7q2f:A, 7q2g:A, 7q2h:A
42 8dqw:A 522 57 0.0855 0.0249 0.2281 8.6 8fs3:A, 8fs5:A, 8fs6:A, 8fs7:A, 8fs8:A, 7sgz:A, 7st9:A, 7stb:A
43 8i90:A 440 64 0.0921 0.0318 0.2188 9.0 8i90:B, 8i94:A, 8i94:B
44 7vpk:A 1055 75 0.1250 0.0180 0.2533 9.5 8iek:P, 8ies:P, 7m5v:A, 7n70:A, 7n72:A, 7n73:A, 7n74:A, 7n77:A, 7n78:A, 7vpi:A, 7vpj:A, 7vpl:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218