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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EYVFESPKMKEILEKIKKISCAECPVLITGESGVGKEVVARLIHKLSDRSKEPFVALNVASIPRDIFEAELFGYEKGAFT
GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVRILAATNRNIKELVKEGKFREDLY
YRLGVIEIEIPPLRERKEDIIPLANHFLKKFSRKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDR
GELSCL

The query sequence (length=246) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1ny5:B 385 246 1.0000 0.6390 1.0000 4.37e-176 4bs1:A, 4bs1:B, 4bt0:A, 4bt0:B, 4bt1:A, 4bt1:B, 4ly6:A, 4ly6:B, 4ly6:C, 4ly6:D, 4ly6:E, 4ly6:G, 4ly6:H, 4ly6:I, 4ly6:J, 4ly6:K, 4ly6:L, 4ly6:M, 4ly6:N, 4ly6:O, 4ly6:P, 4ly6:Q, 4ly6:R, 4ly6:S, 4ly6:T, 4ly6:U, 4ly6:V, 4ly6:W, 4ly6:X, 4lzz:A, 4lzz:B, 4lzz:C, 4lzz:D, 4lzz:E, 4lzz:F, 4lzz:G, 4lzz:H, 4lzz:I, 4lzz:J, 4lzz:K, 4lzz:L, 4lzz:M, 4lzz:N, 4lzz:O, 4lzz:P, 4lzz:Q, 4lzz:R, 4lzz:S, 4lzz:T, 4lzz:U, 4lzz:V, 4lzz:W, 4lzz:X, 3m0e:A, 3m0e:B, 3m0e:C, 3m0e:D, 3m0e:E, 3m0e:F, 3m0e:G, 1ny5:A, 1ny6:A, 1ny6:B, 1ny6:C, 1ny6:D, 1ny6:E, 1ny6:F, 1ny6:G, 1ny6:H, 1ny6:I, 1ny6:J, 1ny6:K, 1ny6:L, 1ny6:M, 1ny6:N, 1zy2:A
2 3dzd:A 368 238 0.5691 0.3804 0.5882 1.99e-92 3dzd:B
3 1ojl:E 285 238 0.4878 0.4211 0.5042 1.56e-81
4 4qht:C 248 238 0.4797 0.4758 0.4958 4.38e-79 6luf:A, 6luf:B, 6luf:C, 6luf:D, 6luf:E, 6luf:F, 6luf:G, 4qht:A, 4qht:B, 4qht:D, 4qht:E, 4qht:F, 4qht:G
5 6iy8:A 469 230 0.4675 0.2452 0.5000 1.36e-76 6iy8:B, 6iy8:C, 6iy8:D
6 5ep3:A 253 232 0.4553 0.4427 0.4828 6.24e-73 5ep2:A, 5ep4:A
7 7qv9:a 259 227 0.4350 0.4131 0.4714 8.40e-70 2c96:A, 2c98:A, 2c99:A, 2c9c:A, 4qnr:A, 4qos:A, 7qv9:b, 7qv9:c, 7qv9:f, 7qv9:e, 2vii:A
8 8pb9:D 390 222 0.4512 0.2846 0.5000 7.10e-69 7ejw:C, 5exs:A, 5ext:A, 5exx:A, 6j7e:A, 6jdi:A, 6jdl:A
9 5m7n:B 428 239 0.3659 0.2103 0.3766 1.83e-54
10 5m7o:A 448 237 0.3659 0.2009 0.3797 2.51e-53 4d6y:A, 4d6y:B, 5m7n:A, 5m7o:B, 5m7p:A, 5m7p:B
11 7v2b:D 376 243 0.3984 0.2606 0.4033 4.00e-52 7v2b:A, 7v3w:A, 7v3w:D
12 7vbw:A 238 227 0.3659 0.3782 0.3965 1.98e-47
13 3zuh:A 286 217 0.2317 0.1993 0.2627 0.002 3zuh:B, 3zuh:C, 3zuh:D, 3zuh:E, 3zuh:F
14 4r7y:A 591 163 0.1585 0.0660 0.2393 0.043 4r7y:B, 4r7z:A, 4r7z:B, 4r7z:C, 4r7z:D, 4r7z:E, 4r7z:F, 4r7z:G, 4r7z:H, 4r7z:I, 4r7z:P, 4r7z:J, 4r7z:K, 4r7z:L, 4r7z:M, 4r7z:N, 4r7z:O
15 3k1j:A 566 98 0.1098 0.0477 0.2755 0.075 3k1j:B
16 6y6n:A 116 56 0.0610 0.1293 0.2679 0.086 6y6o:A
17 8x7u:D 654 128 0.1301 0.0489 0.2500 0.12 8x7u:E, 8x7u:C, 8x7u:B, 8x7u:F, 8x7u:A
18 8ouw:7 632 126 0.1260 0.0491 0.2460 0.21
19 8ouw:4 619 130 0.1341 0.0533 0.2538 0.25
20 7wi4:A 410 68 0.0935 0.0561 0.3382 0.44 7wi4:D, 7wi4:E, 7wi4:F, 7wi4:B, 7wi4:C
21 8q6p:6 395 81 0.0894 0.0557 0.2716 0.51
22 4mrn:A 600 46 0.0691 0.0283 0.3696 0.73 4mrn:B, 4mrp:A, 4mrp:B, 4mrr:A, 4mrr:B, 4mrs:A, 4mrs:B, 4mrv:A, 4mrv:B, 6pam:A, 6pam:B, 6pam:C, 6pam:D, 6pam:E, 6pam:F, 6pam:G, 6pam:H, 6pan:A, 6pan:B, 6pao:A, 6pao:B, 6paq:A, 6paq:B, 6par:A, 6par:B, 6par:C, 6par:D, 6par:E, 6par:F, 6vqt:A, 6vqt:B
23 1um8:A 327 94 0.0976 0.0734 0.2553 0.81
24 6raz:7 601 126 0.1220 0.0499 0.2381 0.96 6ray:7
25 2ehd:B 213 183 0.2073 0.2394 0.2787 1.1 2ehd:A
26 6rax:7 632 126 0.1220 0.0475 0.2381 1.1 6raw:7
27 8kg8:4 697 126 0.1260 0.0445 0.2460 1.4 8b9a:4, 8b9b:4, 8b9c:4, 8kg6:4, 8p5e:4, 8p62:4, 8p63:4, 7pmk:4, 7pmn:4, 7qhs:4, 6sko:4, 8w7m:4, 7z13:4, 7z13:c
28 8ouw:6 707 91 0.0894 0.0311 0.2418 1.9
29 8xoo:O 572 235 0.2073 0.0892 0.2170 2.0
30 8ouw:3 619 122 0.1138 0.0452 0.2295 2.1
31 4fdg:B 592 193 0.1789 0.0743 0.2280 2.1 8eaf:A, 8eaf:B, 8eaf:C, 8eaf:D, 8eaf:E, 8eaf:F, 8eag:B, 8eag:C, 8eag:D, 8eag:E, 8eag:F, 8eag:A, 8eah:A, 8eah:B, 8eah:C, 8eah:D, 8eah:E, 8eah:F, 8eai:B, 8eai:C, 8eai:D, 8eai:E, 8eai:F, 8eai:A, 8eaj:A, 8eaj:B, 8eaj:C, 8eaj:D, 8eaj:E, 8eaj:F, 8eak:B, 8eak:C, 8eak:D, 8eak:E, 8eak:A, 8eak:F, 8eal:A, 8eal:B, 8eal:C, 8eal:D, 8eal:E, 8eal:F, 8eam:B, 8eam:C, 8eam:D, 8eam:E, 8eam:A, 8eam:F, 4fdg:A, 4fdg:C, 4fdg:D, 4fdg:E, 6mii:A, 6mii:B, 6mii:C, 6mii:D, 6mii:E, 6mii:F, 2vl6:A, 2vl6:B, 2vl6:C, 6wnz:B, 6wnz:A
32 5i0i:A 784 75 0.0976 0.0306 0.3200 2.4 5i0h:A, 5i0h:B, 5i0i:B
33 5bk4:D 661 177 0.1707 0.0635 0.2373 2.5 5bk4:5
34 3kd6:A 300 32 0.0488 0.0400 0.3750 2.6 3kd6:B
35 8dgf:A 1541 48 0.0650 0.0104 0.3333 2.8 8dgf:B, 8dgf:C, 8dgf:D
36 5txv:T 318 95 0.1016 0.0786 0.2632 3.0 5txv:P
37 7pmn:5 660 177 0.1707 0.0636 0.2373 3.2
38 8p5e:5 695 177 0.1707 0.0604 0.2373 3.2 6eyc:5, 6f0l:D, 6f0l:5, 3ja8:5, 8kg6:5, 8kg8:5, 8kg9:5, 7p30:5, 7p30:D, 7p5z:5, 7p5z:D, 8p62:5, 8p63:5, 7pmk:5, 6ptn:l, 6ptn:5, 6pto:k, 6pto:5, 7pt6:5, 7pt6:E, 7pt7:5, 7pt7:E, 7qhs:5, 6rqc:5, 6skl:5, 6u0m:5, 5u8s:5, 5u8t:5, 7v3u:5, 7v3u:E, 7v3v:5, 7v3v:E, 7w8g:5, 7w8g:E, 8xgc:5, 7z13:5, 7z13:d
39 1ixs:B 315 143 0.1504 0.1175 0.2587 3.2 8efv:C, 8efv:B, 8efv:A, 8efv:D, 8efv:F, 8efv:E, 8efy:B, 8efy:C, 8efy:A, 8efy:D, 8efy:J, 8efy:K, 8efy:I, 8efy:L, 8efy:E, 8efy:F, 8efy:M, 8efy:N, 1hqc:A, 1hqc:B, 1ixr:C
40 7abv:A 232 56 0.0650 0.0690 0.2857 3.6 3eto:A, 3eto:B, 3i08:A, 3i08:C, 3l95:X, 3l95:Y
41 6y92:A 178 74 0.0854 0.1180 0.2838 4.1 6vja:C, 6vja:D, 6y90:B, 6y90:A, 6y92:B
42 5u8t:6 661 104 0.0976 0.0363 0.2308 4.1 6wgi:6
43 8bx8:C 3947 252 0.2195 0.0137 0.2143 4.3 7k58:C, 7k5b:C, 7kek:C
44 5v8f:6 692 104 0.0976 0.0347 0.2308 4.3 8b9a:6, 8b9b:6, 8b9c:6, 6eyc:6, 3ja8:6, 8kg6:6, 8kg8:6, 8kg9:6, 7p30:6, 7p30:E, 7p5z:6, 7p5z:E, 8p5e:6, 8p62:6, 8p63:6, 7pmk:6, 7pmn:6, 6ptn:m, 6ptn:6, 6pto:l, 6pto:6, 7pt6:6, 7pt6:F, 7pt7:6, 7pt7:F, 6rqc:6, 6skl:6, 6sko:6, 6u0m:6, 5u8s:6, 8w7m:6, 8xgc:6
45 5txv:B 337 62 0.0813 0.0593 0.3226 4.3 6pxk:J, 6pxk:D, 6pxl:E, 6pxl:J, 5txv:A, 5txv:D, 5txv:G, 5txv:J, 5txv:K, 5txv:N, 5txv:S, 5txv:U
46 7v3u:6 646 104 0.0976 0.0372 0.2308 4.5 7qhs:6, 7v3u:F, 7v3v:6, 7v3v:F, 7w8g:6, 7w8g:F, 7z13:6, 7z13:e
47 6dzi:l 200 91 0.1057 0.1300 0.2857 4.7 6dzk:D, 8fr8:e, 5o5j:D, 5o61:BD, 8v9j:d, 8v9k:d, 8v9l:d, 8whx:e, 8wi7:e, 8wi9:e, 8wib:e, 8wid:e, 8wif:e, 5zeb:d, 5zep:d, 5zeu:d
48 5txv:X 360 50 0.0732 0.0500 0.3600 4.8 1g4a:E, 1g4a:F, 5ji2:F, 5ji3:F, 5txv:F, 5txv:I, 5txv:M, 5txv:O, 5txv:R, 5txv:V, 5txv:W
49 3zpc:A 357 118 0.1260 0.0868 0.2627 5.3 3zpc:B, 3zpg:A
50 6hv9:2 549 124 0.1057 0.0474 0.2097 5.9
51 7oik:A 4426 47 0.0772 0.0043 0.4043 6.4 7oim:A, 6tax:A, 6tay:A
52 3fe1:B 387 27 0.0407 0.0258 0.3704 6.4 3fe1:A, 3fe1:C
53 7qep:S8 164 54 0.0650 0.0976 0.2963 6.5
54 4pa0:A 974 35 0.0610 0.0154 0.4286 7.0 4db1:A, 4db1:B, 8efe:A, 8efh:A, 9f6c:A, 6fsa:A, 6fsa:B, 5n69:A, 5n69:B, 5n6a:A, 8qyu:A
55 6skl:4 679 122 0.1016 0.0368 0.2049 7.1 8kg9:4, 8xgc:4
56 8b9a:5 533 81 0.0813 0.0375 0.2469 7.7 8b9b:5, 8b9c:5, 6sko:5
57 6xtx:6 679 125 0.1220 0.0442 0.2400 7.7 8b9d:6, 7pfo:6, 7plo:6, 6xty:6
58 7w1y:6 716 125 0.1220 0.0419 0.2400 8.3 7w1y:E
59 1g3i:A 326 52 0.0691 0.0521 0.3269 8.3 1g3i:B, 1g3i:C, 1g3i:D, 1g3i:E, 1g3i:F, 1g3i:S, 1g3i:U, 1g3i:V, 1g3i:W, 1g3i:X, 1kyi:A, 1kyi:B, 1kyi:C, 1kyi:D, 1kyi:E, 1kyi:F, 1kyi:S, 1kyi:T, 1kyi:U, 1kyi:V, 1kyi:W, 1kyi:X
60 8uo1:A 334 120 0.1138 0.0838 0.2333 8.6 8gga:A
61 5v8f:4 741 99 0.1057 0.0351 0.2626 9.0 5bk4:C, 5bk4:4, 6eyc:4, 6f0l:C, 3ja8:4, 7p30:4, 7p30:C, 7p5z:C, 7p5z:4, 7pt6:4, 7pt6:D, 7pt7:4, 7pt7:D, 6rqc:4, 7v3u:4, 7v3u:D, 7v3v:4, 7v3v:D, 7w8g:4, 7w8g:D
62 7lvy:A 431 35 0.0569 0.0325 0.4000 9.4 7mco:A, 7mco:B
63 8q6p:3 370 66 0.0732 0.0486 0.2727 9.6
64 2chq:A 313 98 0.1057 0.0831 0.2653 9.7 2chg:A, 2chg:B, 2chg:C, 2chg:D, 2chq:B, 2chq:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218