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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQESMNNYLLMGHLLQVRVL
PKGAKIEKLYKYKQLKDNMKQKHEERIKKLAK

The query sequence (length=112) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7ohx:o 112 112 1.0000 1.0000 1.0000 6.08e-79
2 6c0f:o 133 126 1.0000 0.8421 0.8889 3.54e-75 7btb:o, 6cb1:o, 8e5t:o, 6elz:o, 6em1:o, 6em3:o, 6em4:o, 6em5:o, 3jct:o, 6m62:o, 7nac:o, 7ohp:o, 7ohq:o, 7ohr:o, 7ohs:o, 7ohv:o, 7ohw:o, 7r6q:o, 7r7a:o, 7u0h:o, 7uoo:o, 7uqb:o, 7uqz:o, 7v08:o, 8v83:o, 8v84:o, 8v87:o, 6ylx:o, 6yly:o, 5z3g:E
3 8pv1:CI 152 89 0.3839 0.2829 0.4831 3.01e-29 8i9p:CI, 8i9r:CI, 8i9t:CI, 8i9v:CI, 8i9w:CI, 8i9x:CI, 8i9y:CI, 8i9z:CI, 8ia0:CI, 8pv3:CI, 8pv4:CI, 8pv7:CI, 8pvk:CI
4 8esq:o 137 88 0.3839 0.3139 0.4886 7.95e-29 8esr:o, 8etg:o, 8eth:o, 8eti:o, 8eup:o, 8euy:o, 8ev3:o
5 8fkp:SH 150 109 0.3661 0.2733 0.3761 7.07e-20 8fkq:SH, 8fkr:SH, 8fks:SH, 8fkt:SH, 8fku:SH, 8fkv:SH, 8fkw:SH, 8fkx:SH, 8fky:SH, 8fkz:SH, 8fl2:SH, 8fl6:SH, 8fla:SH, 8fld:SH, 8ine:t, 8inf:t, 8ipx:t, 8ipy:t, 8ir3:t
6 1rk8:A 87 73 0.1875 0.2414 0.2877 4.24e-09
7 1fnx:H 174 104 0.2768 0.1782 0.2981 8.67e-09 1fxl:A, 1g2e:A
8 1fnx:H 174 74 0.2054 0.1322 0.3108 3.37e-06 1fxl:A, 1g2e:A
9 7dvq:Y 140 75 0.1875 0.1500 0.2800 8.88e-09 8i0p:Y, 8i0r:Y
10 6jvx:A 87 80 0.2411 0.3103 0.3375 2.41e-08 6jvy:A
11 6n7p:A 186 47 0.1696 0.1022 0.4043 3.48e-08 6n7r:A, 6n7x:A, 7oqc:B, 7oqe:B, 8w2o:A, 5zwn:Q
12 5ith:A 80 74 0.2143 0.3000 0.3243 3.72e-08 5o3j:A
13 6g90:B 193 56 0.1786 0.1036 0.3571 4.08e-08
14 5kw6:A 201 72 0.2143 0.1194 0.3333 4.47e-08 5kvy:A, 5kvy:B, 5kw1:A, 5kw1:B, 5kw6:B, 7q8a:B, 7q8a:A, 2qfj:A, 2qfj:B, 7z3x:A, 7z3x:B
15 5kw6:A 201 72 0.1786 0.0995 0.2778 2.94e-05 5kvy:A, 5kvy:B, 5kw1:A, 5kw1:B, 5kw6:B, 7q8a:B, 7q8a:A, 2qfj:A, 2qfj:B, 7z3x:A, 7z3x:B
16 7q33:A 93 72 0.2143 0.2581 0.3333 1.24e-07 6pai:D, 6q0r:D, 6q0v:D, 6q0w:D, 6sj7:C, 6ud7:C, 6ue5:C
17 7zew:A 117 75 0.2054 0.1966 0.3067 1.97e-07 7zex:A
18 6gd2:A 84 73 0.2054 0.2738 0.3151 2.56e-07 6g2k:A, 6g2k:B, 6gc5:A, 6gc5:B, 6gc5:C, 6gc5:D, 6gd2:B, 6gd3:B, 6gd3:C
19 2mgz:B 105 80 0.2411 0.2571 0.3375 3.31e-07 4ch1:A, 4cio:A, 2ru3:A
20 2n82:B 104 72 0.1964 0.2115 0.3056 4.75e-07 2err:A, 7vrl:B
21 4ed5:B 169 102 0.2679 0.1775 0.2941 6.21e-07 4ed5:A
22 4ed5:B 169 63 0.1696 0.1124 0.3016 1.33e-04 4ed5:A
23 8i0v:4 161 81 0.2411 0.1677 0.3333 1.02e-06
24 8i0v:4 161 74 0.2054 0.1429 0.3108 4.00e-05
25 5mqf:o 223 75 0.2054 0.1031 0.3067 1.20e-06 6id1:y, 7w59:y, 7w5a:y, 7w5b:y
26 2xs2:A 87 63 0.1875 0.2414 0.3333 1.46e-06 2xs5:A, 2xs5:B, 2xs7:A
27 8ch6:V 285 66 0.1875 0.0737 0.3182 1.69e-06 7qtt:V
28 8i0s:Y 320 66 0.1875 0.0656 0.3182 1.75e-06 8i0t:Y, 8i0u:Y, 8i0v:Y
29 8xxm:3G 84 66 0.1786 0.2381 0.3030 3.24e-06 5k0y:O, 8pj1:o, 8pj2:o, 8pj3:o, 8pj4:o, 8pj5:o, 8pj6:o
30 4qqb:A 169 76 0.1964 0.1302 0.2895 3.91e-06 1b7f:A, 1b7f:B, 4qqb:B
31 4qqb:A 169 88 0.2232 0.1479 0.2841 2.88e-05 1b7f:A, 1b7f:B, 4qqb:B
32 2xb2:D 89 73 0.1786 0.2247 0.2740 8.29e-06 2xb2:Z
33 2mkc:A 118 72 0.1518 0.1441 0.2361 1.05e-05 2my3:A
34 6hpj:B 84 72 0.1875 0.2500 0.2917 1.24e-05
35 2rqc:A 115 63 0.1607 0.1565 0.2857 1.30e-05
36 7dco:X 128 72 0.1518 0.1328 0.2361 1.55e-05 5gm6:V, 5zwm:X
37 2rs2:A 84 59 0.1696 0.2262 0.3220 1.91e-05
38 8h6e:4R 106 73 0.1607 0.1698 0.2466 2.25e-05 8h6j:4R, 8qp8:R, 8qp9:R, 8qpk:R, 6qw6:R, 6qx9:R, 8qxd:R, 8r08:R, 8r0a:R
39 8any:A6 74 73 0.1964 0.2973 0.3014 2.41e-05
40 5m8i:A 114 63 0.1429 0.1404 0.2540 2.72e-05
41 3smz:A 280 77 0.1964 0.0786 0.2857 6.32e-05
42 8y6o:W 167 47 0.1518 0.1018 0.3617 7.26e-05
43 2cjk:A 167 57 0.1607 0.1078 0.3158 7.34e-05 2km8:C
44 2cjk:A 167 78 0.1607 0.1078 0.2308 2.22e-04 2km8:C
45 2mgz:A 94 72 0.1696 0.2021 0.2639 8.36e-05
46 4bs2:A 174 46 0.1518 0.0977 0.3696 9.34e-05 4iuf:A, 4y00:A, 4y00:B, 4y00:C, 4y00:D, 4y0f:A, 4y0f:B
47 4bs2:A 174 66 0.1607 0.1034 0.2727 0.031 4iuf:A, 4y00:A, 4y00:B, 4y00:C, 4y00:D, 4y0f:A, 4y0f:B
48 2i2y:A 150 72 0.1875 0.1400 0.2917 9.40e-05 9asq:H, 5bmg:A, 5bmg:B, 5bmg:H, 5bmg:D, 5bmg:E, 5bmg:F, 5bmg:G, 5bmh:A, 3v3x:C, 3v3x:D
49 2x1f:A 94 75 0.1607 0.1915 0.2400 9.79e-05 2km8:B, 2x1a:A
50 7dco:4 174 103 0.2589 0.1667 0.2816 1.25e-04 6g90:R, 5gm6:e, 5nrl:R, 7oqb:R, 7oqe:R, 5zwm:4
51 5x8p:v 190 77 0.1786 0.1053 0.2597 1.38e-04 5mmj:v, 5mmm:v, 5x8r:v
52 5x8p:v 190 72 0.1607 0.0947 0.2500 1.70e-04 5mmj:v, 5mmm:v, 5x8r:v
53 6xlv:A 203 58 0.1607 0.0887 0.3103 3.00e-04 5ev1:A, 5ev2:A, 5ev3:A, 5ev4:A, 2g4b:A, 2hzc:A, 7s3a:A, 7s3b:A, 7s3c:A, 4tu7:A, 4tu7:B, 4tu8:A, 4tu8:B, 4tu9:A, 4tu9:B, 3vaf:A, 3vaf:B, 3vag:A, 3vag:B, 3vah:B, 3vah:A, 3vai:A, 3vai:B, 3vaj:A, 3vaj:B, 3vak:A, 3vak:B, 3val:I, 3val:A, 3val:D, 3val:B, 3vam:A, 3vam:B, 5w0g:A, 6xlw:A, 6xlx:A, 2yh1:A
54 7csz:A 175 54 0.1518 0.0971 0.3148 7.35e-04
55 7csz:A 175 56 0.1339 0.0857 0.2679 0.003
56 6zj3:Sg 199 99 0.2857 0.1608 0.3232 8.15e-04
57 7uj1:B 270 81 0.2054 0.0852 0.2840 8.59e-04 7pu5:B, 7pu5:D, 7pu5:H, 7pu5:J, 7pu5:L, 7sp0:B, 7uj1:A
58 6m75:A 167 58 0.1786 0.1198 0.3448 8.65e-04
59 3jb9:Y 261 75 0.2054 0.0881 0.3067 0.001
60 7abi:P 237 77 0.1786 0.0844 0.2597 0.001 7aav:P, 7abg:P
61 5ifm:C 256 73 0.1964 0.0859 0.3014 0.001 5ifm:A
62 6r5k:H 394 79 0.1875 0.0533 0.2658 0.001 6r5k:D, 6r5k:F
63 6r5k:H 394 72 0.1786 0.0508 0.2778 0.012 6r5k:D, 6r5k:F
64 7slp:B 321 58 0.1518 0.0530 0.2931 0.001 6d12:A, 6d12:B, 7slq:B, 4wkr:A, 4wkr:B
65 4f02:A 175 67 0.1875 0.1200 0.3134 0.004 1cvj:A, 1cvj:B, 1cvj:C, 1cvj:D, 1cvj:E, 1cvj:F, 1cvj:G, 1cvj:H, 4f02:D
66 1wtb:A 79 53 0.1339 0.1899 0.2830 0.004 1x0f:A
67 8ch6:U 295 75 0.1696 0.0644 0.2533 0.005 7a5p:P, 8c6j:M, 6ff4:P, 6ff7:P, 9fmd:O, 8i0p:O, 8i0r:O, 8i0s:O, 8i0t:O, 8i0u:O, 8i0v:O, 8i0w:O, 6icz:O, 6id0:O, 6id1:O, 5mqf:P, 6qdv:M, 7qtt:U, 8ro2:O, 7w59:O, 7w5a:O, 7w5b:O, 5xjc:O, 5yzg:O, 5z56:O, 5z57:O, 6zym:P
68 2n7c:A 89 74 0.1786 0.2247 0.2703 0.007
69 7abg:B 169 65 0.1964 0.1302 0.3385 0.009 7a5p:X, 1a9n:B, 1a9n:D, 7abi:B, 6ah0:p, 6ahd:p, 8c6j:Y, 8ch6:s, 7evo:G, 9fmd:p, 8h6e:2C, 8h6j:2C, 8h6k:2C, 8h6l:2C, 8hk1:G, 8i0p:p, 8i0r:p, 8i0s:p, 8i0t:p, 8i0u:p, 8i0v:p, 8i0w:p, 6icz:p, 6id0:p, 6id1:p, 5mqf:X, 6qdv:Y, 8qo9:2B, 6qx9:2B, 8qxd:2B, 8qzs:2B, 8r08:2B, 8r09:2B, 8r0a:2B, 8r0b:2B, 8rm5:2B, 7vpx:G, 7w59:p, 7w5a:p, 7w5b:p, 5xjc:p, 6y53:b, 6y5q:b, 5yzg:p, 5z56:p, 5z57:p, 5z58:p
70 7zap:A 97 56 0.0982 0.1134 0.1964 0.021
71 7qde:B 169 72 0.1786 0.1183 0.2778 0.029 7qdd:B
72 5en1:A 184 75 0.1518 0.0924 0.2267 0.031 8hni:A, 8hni:B, 8hni:G, 8hni:I, 8hni:H, 8hni:E, 8hni:K, 8hni:C, 8hni:D, 8hni:J, 8hni:F, 8hni:L, 5ho4:A, 7wm3:A, 7wm3:B, 7wm3:C, 7wm3:D, 5wwe:A, 5wwf:A, 5wwf:C, 5wwg:A
73 5en1:A 184 58 0.1429 0.0870 0.2759 0.16 8hni:A, 8hni:B, 8hni:G, 8hni:I, 8hni:H, 8hni:E, 8hni:K, 8hni:C, 8hni:D, 8hni:J, 8hni:F, 8hni:L, 5ho4:A, 7wm3:A, 7wm3:B, 7wm3:C, 7wm3:D, 5wwe:A, 5wwf:A, 5wwf:C, 5wwg:A
74 9gpj:A 184 75 0.1607 0.0978 0.2400 0.044 6dcl:A, 6dcl:B, 9f4d:A, 9f4e:A, 9f4f:A, 9f4g:A, 9f4h:A, 9f4j:A, 9f4k:A, 9f4l:A, 9f4m:A, 9f4n:A, 9f4o:A, 9f4p:A, 9f4q:A, 9f4r:A, 9f4s:A, 9f4t:A, 9f4u:A, 9f4v:A, 9f4w:A, 9f4x:A, 9f4y:A, 9f4z:A, 9f50:A, 9f51:A, 9f52:A, 9f53:A, 9f54:A, 9f55:A, 9f5c:A, 9f5d:A, 9f5e:A, 9f5f:A, 9f5g:A, 9f5k:A, 9f7f:A, 9f7h:A, 5mpg:A, 5mpl:A, 1pgz:A, 1po6:A, 8rzv:A, 1u1k:A, 1u1l:A, 1u1m:A, 1u1n:A, 1u1o:A, 1u1p:A, 1u1q:A, 1u1r:A, 2up1:A, 4yoe:A
75 9gpj:A 184 56 0.1250 0.0761 0.2500 0.070 6dcl:A, 6dcl:B, 9f4d:A, 9f4e:A, 9f4f:A, 9f4g:A, 9f4h:A, 9f4j:A, 9f4k:A, 9f4l:A, 9f4m:A, 9f4n:A, 9f4o:A, 9f4p:A, 9f4q:A, 9f4r:A, 9f4s:A, 9f4t:A, 9f4u:A, 9f4v:A, 9f4w:A, 9f4x:A, 9f4y:A, 9f4z:A, 9f50:A, 9f51:A, 9f52:A, 9f53:A, 9f54:A, 9f55:A, 9f5c:A, 9f5d:A, 9f5e:A, 9f5f:A, 9f5g:A, 9f5k:A, 9f7f:A, 9f7h:A, 5mpg:A, 5mpl:A, 1pgz:A, 1po6:A, 8rzv:A, 1u1k:A, 1u1l:A, 1u1m:A, 1u1n:A, 1u1o:A, 1u1p:A, 1u1q:A, 1u1r:A, 2up1:A, 4yoe:A
76 3lqv:B 115 59 0.0982 0.0957 0.1864 0.062 2f9j:B, 3lqv:A, 7q4o:F, 8qo9:B6, 8qxd:B6, 8qzs:B6, 8r08:B6, 8r09:B6, 8r0a:B6, 8r0b:B6, 8rm5:B6
77 8idf:A 459 75 0.1875 0.0458 0.2800 0.066
78 5x3z:A 96 47 0.1339 0.1562 0.3191 0.077
79 8by6:B 152 75 0.1518 0.1118 0.2267 0.098 7abg:A1, 6d0y:A, 1h2t:Z, 1h2u:X, 1h2u:Y, 1n52:B, 5oo6:B, 5oo6:E, 5oo6:H, 5oo6:K, 5oo6:N, 5oo6:Q, 5oo6:T, 5oo6:W, 5oob:D, 5oob:J, 5oob:B, 5oob:G, 8pmp:B, 8pnt:B, 8srr:B, 8suy:B
80 7pcv:A 116 71 0.1875 0.1810 0.2958 0.20 2lk0:A, 2lk1:A, 7pcv:B, 7pdv:E, 7pdv:A, 7pdv:C, 7pdv:G
81 2yka:A 124 82 0.1696 0.1532 0.2317 0.22
82 2m8d:B 91 68 0.1607 0.1978 0.2647 0.56 7abg:A6
83 3d2w:A 72 66 0.1250 0.1944 0.2121 0.75
84 7dco:R 261 48 0.1250 0.0536 0.2917 0.84 7b9v:M, 6bk8:G, 6exn:M, 5gm6:R, 5gmk:R, 6j6g:R, 6j6h:R, 6j6n:R, 6j6q:R, 5lj3:M, 5lj5:M, 5mps:M, 5mq0:M, 3tp2:A, 3tp2:B, 3u1l:A, 3u1m:A, 5wsg:R, 5y88:N, 5ylz:N
85 5lqw:F 218 48 0.1250 0.0642 0.2917 0.87
86 8wq5:A 99 35 0.1071 0.1212 0.3429 1.3 8wq5:B, 8wq5:C, 8wq5:D
87 8ro0:O 342 78 0.1964 0.0643 0.2821 1.8 8ro1:O
88 2mki:A 203 70 0.1786 0.0985 0.2857 4.6
89 5xss:A 274 80 0.1607 0.0657 0.2250 5.0 5xsj:X, 5xss:X, 5xss:B, 5xss:C
90 4n8g:A 325 56 0.1607 0.0554 0.3214 6.1 4n8g:B, 4n8g:C, 4n8g:D
91 7d5m:A 389 54 0.1518 0.0437 0.3148 6.5 7d5n:A, 7d5n:B
92 8oh5:C 1172 23 0.1071 0.0102 0.5217 6.8 8oh5:F, 8oh5:I, 8oh5:L, 8oh9:C, 8oh9:F, 8oh9:I, 8oh9:L
93 5vsu:A 387 79 0.1607 0.0465 0.2278 8.3 6aso:A, 2kh9:A, 4n0t:A, 5tf6:A, 5tf6:C
94 3j0a:B 632 62 0.1696 0.0301 0.3065 9.3
95 4ewt:A 389 24 0.0982 0.0283 0.4583 9.8 4ewt:C, 4ewt:D, 4ewt:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218