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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EVRVVVDNDPVPTSFQKWSQPGHFDRTLAKGAKTTTWIWNLHANAHDFDTHTSDLEDISRKIFAAHFGHLAVVFIWLSGM
YFHGARFSNFEAWMANPTGIKPSAQVVWPIFGQEILNGDMGGGFHGIQITSGLFQMWRAAGFTNTFQLYCTAIGGLVMAA
LMLFAGWFHYHKRAPKLEWFQNTQSMLNHHLAGLLGLGSLGWTGHLIHVSLPTNKLLDTGVALKDIPLPHEFILNPSLMN
KLYPHADWGFVKGVVPFFTLQWGHFTDFLTFKGGLNPVTGGLWLTDVAHHHLAIAVMFIIAGHMYRTNWGIGHSIKEMLD
DARTPNMLPFLSFIGPVGHKGLFEVLTTSWHAQLSINLAMLGSLSIIIAHHMYAMPPYPYLATDYGTVVSLFTHHVWIGG
FLIVGGAAHAAIYMVRDYDPEQNFNNVLDRVLRHRDAIISHLAWVCQFLGFHSFAMYCHNDTMRAFGRPQDMFSDTGIQL
QPVFAQWLQHIHTMTIAAPNLHDPVSYAFGGGVVAVGGKVAMMPITLGTADFLIHHIHAFTIHVTVLVLLKGVLFARSSR
LIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNSLSMVIFHFFWKMQSDVWGTVGADGVVTHITGGNFATSSI
TNNGWLRDFLWAQSTQVITSYNTSLSAYGLMFLGGHFIFGFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSI
IHGRAVGVAHYLLGGIVTTWAFFLARMTAFG

The query sequence (length=751) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7lx0:G 751 751 1.0000 1.0000 1.0000 0.0 7lx0:a, 7lx0:A, 6pnj:A, 6pnj:G, 6pnj:a
2 7s3d:A 749 749 0.8229 0.8251 0.8251 0.0 7s3d:G, 7s3d:a
3 6tra:A 746 753 0.8282 0.8338 0.8260 0.0 4fe1:A, 7fix:A1, 7fix:A2, 7fix:A3, 1jb0:A, 6k33:aA, 6k33:bA, 6k33:cA, 6lu1:A, 7m75:A, 7m76:A, 7m78:A, 3pcq:A, 6pfy:A, 6pfy:G, 6pfy:Y, 6pgk:A, 6pgk:G, 6pgk:Y, 6trc:A, 6trc:a, 6trc:1, 6trd:A, 6trd:a, 6trd:1, 5zf0:A1, 5zf0:A2, 5zf0:A3, 5zf0:A4, 5zf0:A6, 5zf0:A5
4 6k61:A 742 753 0.8069 0.8167 0.8048 0.0 6jeo:aA, 6jeo:bA, 6jeo:cA, 6jeo:dA, 6k61:a, 6tcl:A1, 6tcl:A2, 6tcl:A, 6tcl:AA, 7y3f:A
5 5oy0:A 751 753 0.7909 0.7909 0.7888 0.0 8am5:a, 8asl:a, 8asp:a, 6hqb:A, 4kt0:A, 4l6v:A, 4l6v:a, 4l6v:1, 6nwa:A, 6nwa:a, 6nwa:H, 7o1v:A, 5oy0:a, 5oy0:1, 7umh:A, 7umh:H, 7umh:a, 6uzv:A, 6uzv:a, 6uzv:1, 6vpv:A, 6vpv:a, 6vpv:1
6 7dr0:A 739 751 0.7736 0.7862 0.7736 0.0 7dr1:A, 7dr2:aA, 7dr2:bA, 7dr2:cA, 7dr2:dA
7 7y5e:AN 745 753 0.7683 0.7745 0.7663 0.0 7y5e:A2, 7y7a:A7, 7y7a:Ao
8 6kmx:aA 717 721 0.7763 0.8131 0.8086 0.0 6kmx:bA, 6kmx:cA
9 6kif:A 751 764 0.7856 0.7856 0.7723 0.0 6kif:G, 6kif:e, 6kig:A, 6kig:G, 6kig:e
10 8wm6:A 742 753 0.7537 0.7628 0.7517 0.0 8wmj:A, 8wmv:A, 8wmw:A, 7y7b:A, 7y8a:A
11 7yca:A 742 752 0.7577 0.7668 0.7566 0.0 7a4p:A, 7bgi:A, 7blx:A, 8cmo:A, 7d0j:A, 7dz7:A, 7dz8:A, 8h2u:A, 6ijj:A, 6ijo:A, 6jo5:A, 6jo6:A, 7r3k:A, 7wyi:A, 7wzn:A, 7zq9:A, 7zqc:A, 7zqd:A, 7zqd:A2, 6zzx:A, 6zzy:A
12 7qco:A 728 740 0.7803 0.8049 0.7919 0.0 7qco:E, 7qco:e, 7qco:a
13 5l8r:A 743 754 0.7617 0.7699 0.7586 0.0 8bcv:A, 8bcw:A, 7dkz:A, 7ew6:A, 7ewk:A, 7f9o:A, 7f9o:e, 8htu:A, 8j6z:A, 8j7a:A, 8j7b:A, 7ksq:A, 7kux:A, 6l35:A, 3lw5:A, 2o01:A, 4rku:A, 7wfd:AA, 7wfe:BA, 7wg5:AA, 7wg5:BA, 8wgh:A, 2wsc:A, 2wse:A, 2wsf:A, 4xk8:A, 4xk8:a, 7xqp:A, 4y28:A, 6yac:A, 6yez:A, 5zji:A, 6zoo:A, 6zxs:A
14 7blz:A 743 742 0.7630 0.7712 0.7722 0.0 6fos:A, 8wey:A, 5zgb:A, 5zgh:A
15 6igz:A 740 756 0.7563 0.7676 0.7513 0.0 6qph:A, 6rhz:A, 6sl5:A, 6yxr:A
16 6ly5:a 742 748 0.7337 0.7426 0.7366 0.0 6l4u:A
17 6kmw:aA 721 733 0.7443 0.7753 0.7626 0.0 6kmw:bA, 6kmw:cA
18 7dwq:A 726 735 0.6937 0.7176 0.7088 0.0
19 7f4v:aA 772 783 0.7111 0.6917 0.6820 0.0 7f4v:bA, 7f4v:cA
20 7coy:aA 685 725 0.6711 0.7358 0.6952 0.0 7coy:bA, 7coy:cA
21 8jjr:a 665 736 0.4447 0.5023 0.4538 0.0
22 8jze:a 670 734 0.4234 0.4746 0.4332 0.0 8jzf:a
23 8jw0:a 645 727 0.4581 0.5333 0.4732 0.0
24 6kmw:aB 740 781 0.4474 0.4541 0.4302 0.0 6kmw:cB, 6kmw:bB
25 6ly5:b 732 765 0.4434 0.4549 0.4353 0.0 6l4u:B
26 6vpv:B 737 762 0.4434 0.4518 0.4370 0.0 8am5:b, 8asl:b, 8asp:b, 6hqb:B, 4kt0:B, 4l6v:B, 4l6v:b, 4l6v:2, 6nwa:B, 6nwa:b, 6nwa:G, 7o1v:B, 5oy0:B, 5oy0:b, 5oy0:2, 7umh:B, 7umh:G, 7umh:b, 6uzv:B, 6uzv:b, 6uzv:2, 6vpv:b, 6vpv:2
27 7blz:B 731 778 0.4527 0.4651 0.4370 0.0 6fos:B, 8wey:B, 5zgb:B, 5zgh:B
28 7y5e:BN 732 748 0.4434 0.4549 0.4452 0.0 7y5e:B2, 7y7a:B7, 7y7a:Bo, 7y7b:B, 7y8a:B
29 7s3d:B 742 779 0.4501 0.4555 0.4339 0.0 7s3d:H, 7s3d:b
30 8wm6:B 732 768 0.4514 0.4631 0.4414 0.0 8wmj:B, 8wmv:B, 8wmw:B
31 7f4v:aB 725 757 0.4434 0.4593 0.4399 0.0 7f4v:bB, 7f4v:cB
32 7qco:B 734 762 0.4407 0.4510 0.4344 0.0 7qco:G, 7qco:g, 7qco:b
33 7fix:B1 740 773 0.4474 0.4541 0.4347 0.0 7bw2:B, 4fe1:B, 7fix:B2, 7fix:B3, 1jb0:B, 6k33:aB, 6k33:bB, 6k33:cB, 7m75:B, 7m76:B, 7m78:B, 3pcq:B, 6pfy:H, 6pfy:B, 6pfy:Z, 6pgk:H, 6pgk:B, 6pgk:Z, 6tra:B, 6trc:B, 6trc:b, 6trc:2, 6trd:B, 6trd:b, 6trd:2, 5zf0:B1, 5zf0:B2, 5zf0:B3, 5zf0:B4, 5zf0:B6, 5zf0:B5
34 6kif:B 733 756 0.4407 0.4516 0.4378 0.0 6kif:H, 6kif:f, 6kig:B, 6kig:H, 6kig:f
35 6igz:B 733 748 0.4314 0.4420 0.4332 0.0
36 7d0j:B 734 748 0.4381 0.4482 0.4398 0.0 7a4p:B, 7bgi:B, 7blx:B, 8cmo:B, 7dz7:B, 7dz8:B, 8h2u:B, 6ijj:B, 6ijo:B, 6jo5:B, 6jo6:B, 6qph:B, 7r3k:B, 6rhz:B, 6sl5:B, 7wyi:B, 7wzn:B, 6yxr:B, 7zq9:B, 7zqc:B, 7zqd:B, 7zqd:B2, 6zzx:B, 6zzy:B
37 7yca:B 732 758 0.4368 0.4481 0.4327 0.0
38 6kmx:aB 727 780 0.4328 0.4470 0.4167 0.0 6kmx:bB, 6kmx:cB
39 7lx0:H 739 780 0.4368 0.4438 0.4205 0.0 7lx0:b, 7lx0:B, 6pnj:H, 6pnj:B, 6pnj:b
40 7wfd:AB 734 766 0.4301 0.4401 0.4217 0.0 8bcv:B, 8bcw:B, 7dkz:B, 7ew6:B, 7ewk:B, 7f9o:B, 7f9o:f, 8htu:B, 8j6z:B, 8j7a:B, 8j7b:B, 7ksq:B, 7kux:B, 6l35:B, 5l8r:B, 3lw5:B, 2o01:B, 4rku:B, 7wfe:BB, 7wg5:AB, 7wg5:BB, 8wgh:B, 2wsc:B, 2wse:B, 2wsf:B, 4xk8:B, 4xk8:b, 7xqp:B, 4y28:B, 6yac:B, 6yez:B, 5zji:B, 6zoo:B, 6zxs:B
41 6k61:B 740 752 0.4328 0.4392 0.4322 0.0 6jeo:aB, 6jeo:bB, 6jeo:cB, 6jeo:dB, 6k61:b, 6tcl:B1, 6tcl:B2, 6tcl:B, 6tcl:BB, 7y3f:B
42 6lu1:B 713 770 0.4288 0.4516 0.4182 0.0
43 7dr0:B 706 762 0.4181 0.4448 0.4121 0.0 7dr1:B, 7dr2:aB, 7dr2:bB, 7dr2:cB, 7dr2:dB
44 7dwq:B 659 741 0.4008 0.4568 0.4062 2.14e-171 7coy:aB, 7coy:bB, 7coy:cB
45 8jze:b 663 724 0.3103 0.3514 0.3218 1.34e-97 8jzf:b
46 8jw0:b 617 719 0.3023 0.3679 0.3157 4.37e-96
47 8jjr:b 659 758 0.3103 0.3536 0.3074 3.91e-95
48 7zq9:B2 180 192 0.0826 0.3444 0.3229 1.24e-15
49 5v8k:A 600 227 0.0852 0.1067 0.2819 1.13e-13
50 7vzg:a 858 125 0.0479 0.0420 0.2880 5.68e-04 7vzg:A, 7vzr:A, 7vzr:a
51 6m32:A 628 81 0.0346 0.0414 0.3210 6.13e-04 6m32:a
52 8gwa:A 667 81 0.0346 0.0390 0.3210 7.04e-04 8gwa:a, 7uea:A, 7uea:a, 7ueb:A, 7ueb:a, 7z6q:A, 7z6q:a
53 8abs:A 394 63 0.0280 0.0533 0.3333 0.79 8abr:A, 5ofq:A, 5ofq:B, 5ofq:C, 5ofq:D
54 6w6w:A 905 86 0.0333 0.0276 0.2907 3.3
55 3bn1:A 368 43 0.0253 0.0516 0.4419 4.1 3bn1:B, 3dr4:A, 3dr4:B, 3dr4:C, 3dr4:D, 3dr7:A, 3dr7:B, 3dr7:C, 3dr7:D
56 8aw7:A 309 54 0.0253 0.0615 0.3519 4.1 8at8:A, 8bbv:A, 9f0f:A, 9f0g:A, 8ofl:A, 8omm:A, 6sv3:A
57 5upm:A 753 65 0.0280 0.0279 0.3231 4.6 5t4a:A, 5t4c:A, 5t4g:A, 5upi:A, 5upn:A, 5upo:A, 5v1w:A
58 8d0b:A 1116 88 0.0333 0.0224 0.2841 6.1 8d0k:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218