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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EVKGIPVRVALRCRPLVSKEIKEGCQTCLSFVPGEPQVVVGNDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNAT
VLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEINKKSDFEFTLKVSYLEIYNEEILDLLCSTQINIREDP
KEGIKIVGLTEKTVLVASDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSERQ
KKTKAEGDRLREGININRGLLCLGNVISALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTL
RYADRARKIKNKPIINHHHH

The query sequence (length=340) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3zfd:A 340 340 1.0000 1.0000 1.0000 0.0 3zfc:A
2 7x4n:E 332 336 0.5235 0.5361 0.5298 6.44e-110
3 7rx0:C 328 327 0.4735 0.4909 0.4924 5.92e-104 6mlq:C, 6mlr:C
4 7a5e:A 338 340 0.4882 0.4911 0.4882 3.28e-98 7a5e:B
5 2xt3:A 300 327 0.4441 0.5033 0.4618 1.80e-88 4a14:A
6 4aqv:C 361 357 0.4529 0.4266 0.4314 1.04e-85 4a28:A, 4a50:A, 4a5y:A, 4a5y:C, 4as7:A, 4b7b:A, 4bbg:A, 4bxn:A, 4bxn:B, 3cjo:A, 3cjo:B, 4ck6:C, 4ck7:C, 2fky:A, 2fky:B, 2fl2:A, 2fl2:B, 2fl6:A, 2fl6:B, 2fme:B, 2g1q:A, 2g1q:B, 6g6z:A, 6hkx:B, 3hqd:A, 3hqd:B, 2ieh:A, 2ieh:B, 1ii6:A, 1ii6:B, 3k3b:A, 3k3b:B, 3k5e:A, 3ken:A, 3l9h:A, 3l9h:B, 2pg2:A, 2pg2:B, 1q0b:A, 1q0b:B, 2q2y:A, 2q2y:B, 2q2z:A, 2q2z:B, 6ta4:K, 6tle:A, 6tle:B, 6trl:B, 2uyi:A, 2uyi:B, 2uym:A, 2uym:B, 2wog:A, 2wog:B, 2wog:C, 2x2r:A, 2x2r:C, 2x7c:A, 2x7c:B, 2x7d:A, 2x7d:B, 2x7e:A, 2x7e:B, 1x88:A, 1x88:B, 2xae:C, 1yrs:A, 1yrs:B, 4zca:A, 4zhi:A, 4zhi:B, 5zo7:A, 5zo7:B
7 7lxr:B 344 348 0.4647 0.4593 0.4540 1.65e-85 7lxr:A, 6vpo:C, 2wbe:C
8 6zpi:C 332 298 0.4353 0.4458 0.4966 3.00e-84 4bn2:A, 4bn2:B, 6zph:B
9 6wwk:K 368 358 0.4529 0.4185 0.4302 3.08e-83 7lvq:K, 7lvr:K, 6wwf:K, 6wwg:K, 6wwg:N, 6wwh:K, 6wwh:N, 6wwj:K, 6wwk:N, 6wwl:K, 6wwl:N, 6wwm:K, 6wwn:K, 6wwo:K, 6wwq:K, 6wwr:K, 6wws:K, 6wwu:K, 6wwv:K
10 1t5c:A 322 336 0.4353 0.4596 0.4405 6.47e-83 8hfh:A, 6m4i:A, 6m4i:B, 1t5c:B
11 1goj:A 354 336 0.4412 0.4237 0.4464 9.10e-83
12 6ta3:K 334 350 0.4412 0.4491 0.4286 2.11e-82 4a1z:A, 4a1z:B, 4a28:B, 4a51:A, 4a51:B, 4a51:C, 4a51:D, 4ap0:A, 2fme:A, 6g6y:A, 2gm1:A, 2gm1:E, 6hkx:A, 6hky:A, 6hky:B, 3k5e:B, 6tiw:K, 2x2r:B, 2xae:A, 2xae:B, 6y1i:A, 6y1i:B, 6y1i:C, 8yhh:A, 3zcw:A, 4zca:B
13 3b6u:B 343 343 0.4353 0.4315 0.4315 9.76e-82 3b6u:A
14 4uy0:C 333 337 0.4382 0.4474 0.4421 1.29e-81
15 5ocu:K 333 330 0.4265 0.4354 0.4394 5.27e-81 5ogc:K
16 5zo8:A 331 346 0.4294 0.4411 0.4220 8.80e-81 4a51:G, 4a51:E, 4a51:F, 4a5y:B, 4ap0:D, 4ap0:B, 2gm1:B, 2gm1:D, 6hky:C, 6trl:A, 8yhh:B, 5zo8:B, 5zo9:A, 5zo9:B
17 7a3z:A 307 337 0.4441 0.4919 0.4481 2.68e-80
18 8uto:N 389 369 0.4353 0.3805 0.4011 4.20e-80 2hxh:C, 1i5s:A, 8utn:K, 8utn:N, 8uto:K, 8utp:K, 8utp:N, 8utq:K, 8utr:K, 8utt:K, 8utt:N, 8utu:K, 8utv:K, 8uty:K, 8uty:N, 4uxp:C, 1vfz:A
19 7z2b:K 308 329 0.3971 0.4383 0.4103 2.53e-78
20 6s8m:K 344 343 0.4118 0.4070 0.4082 3.28e-77
21 7tr1:K 346 353 0.4265 0.4191 0.4108 3.33e-77 7lff:A, 7lff:B
22 5m5i:C 369 357 0.4176 0.3848 0.3978 6.88e-76 5m5l:C, 5m5m:C, 5m5n:C, 5m5o:C
23 1mkj:A 336 334 0.4088 0.4137 0.4162 7.52e-76 4atx:C, 1bg2:A, 4hna:K, 8ixa:Y, 8ixa:S, 8ixa:T, 8ixa:U, 8ixa:V, 8ixa:W, 8ixa:X, 8ixa:Z, 8ixa:a, 8ixb:l, 8ixb:g, 8ixb:k, 8ixb:m, 8ixd:Y, 8ixd:S, 8ixd:T, 8ixd:U, 8ixd:V, 8ixd:W, 8ixd:X, 8ixd:Z, 8ixd:a, 8ixe:l, 8ixe:h, 8ixe:p, 8ixe:q, 8ixf:Y, 8ixf:S, 8ixf:T, 8ixf:U, 8ixf:V, 8ixf:W, 8ixf:X, 8ixf:Z, 8ixf:a, 8ixg:l, 8ixg:h, 8ixg:p, 8ixg:q, 3j8y:K, 2p4n:K
24 2vvg:B 309 334 0.4147 0.4563 0.4222 1.34e-75 2vvg:A
25 4ap0:C 311 342 0.4176 0.4566 0.4152 2.48e-75
26 5hnw:K 329 324 0.4147 0.4286 0.4352 4.96e-75 5hle:A, 5hny:K, 3x2t:B
27 4ozq:B 687 337 0.4353 0.2154 0.4392 3.42e-74 4ozq:A
28 7tr3:K 418 303 0.3971 0.3230 0.4455 4.22e-74 7tqx:K, 7tqy:K, 7tr0:K
29 4bn2:C 311 339 0.4324 0.4727 0.4336 6.92e-74
30 3b6v:A 306 339 0.4000 0.4444 0.4012 1.85e-72 3b6v:B
31 2y65:C 343 336 0.4029 0.3994 0.4077 5.43e-72 2y5w:A, 2y5w:B, 2y65:D, 2y65:B, 2y65:A
32 7nba:K 331 343 0.3912 0.4018 0.3878 8.49e-72
33 7eo9:A 351 356 0.4147 0.4017 0.3961 9.88e-72 7eob:A, 2hxf:C, 1i6i:A, 1ia0:K, 1vfv:A, 1vfw:A, 1vfx:A, 2zfi:A, 2zfj:A, 2zfk:A, 2zfl:A, 2zfm:A
34 7rs5:K 346 297 0.3824 0.3757 0.4377 1.21e-71 7rs5:a, 7rs5:b, 7rs5:c, 7rs5:d, 7rs5:e, 7rs5:f, 7rs5:g, 7rs5:h, 7rs6:K, 7rs6:a, 7rs6:b, 7rs6:c, 7rs6:d, 7rs6:e, 7rs6:f, 7rs6:g, 7rs6:h
35 7wrg:A 812 364 0.4353 0.1823 0.4066 1.92e-71
36 3x2t:A 311 337 0.4059 0.4437 0.4095 8.93e-71 2kin:A, 3kin:A, 3kin:C
37 6a20:A 395 350 0.4353 0.3747 0.4229 1.57e-69 6a1z:A, 7d8v:A, 3gbj:B, 5zbr:B, 5zbr:A, 5zbr:C, 5zbs:B, 5zbs:A
38 2owm:A 328 320 0.4000 0.4146 0.4250 3.16e-69 2owm:B, 2owm:C, 2owm:D
39 5mm7:K 397 317 0.3794 0.3249 0.4069 3.26e-69 5mm4:K
40 7wrg:B 783 359 0.4235 0.1839 0.4011 5.02e-68
41 3cob:A 355 337 0.3941 0.3775 0.3976 1.32e-67 3cob:C, 1sdm:A
42 3wpn:A 309 350 0.4118 0.4531 0.4000 4.10e-67
43 3lre:B 300 327 0.4000 0.4533 0.4159 6.40e-67 3lre:A, 7rsi:C
44 5gsz:A 306 337 0.3971 0.4412 0.4006 5.86e-66
45 7n61:0X 420 343 0.3765 0.3048 0.3732 1.72e-65 7n61:0Y, 7n61:0Z, 7n61:1A
46 5wde:A 320 335 0.4147 0.4406 0.4209 1.91e-65
47 5zbs:C 323 347 0.4147 0.4365 0.4063 5.14e-65 3gbj:A, 3gbj:C
48 6b0l:K 368 340 0.3588 0.3315 0.3588 6.49e-60 6b0c:K
49 3h4s:A 359 334 0.3794 0.3593 0.3862 1.83e-59 4frz:A, 4frz:B
50 5mio:C 477 336 0.3735 0.2662 0.3780 6.44e-58 1v8j:A, 5xjb:A
51 1cz7:D 365 332 0.3676 0.3425 0.3765 2.37e-55 1cz7:A, 1cz7:B, 1cz7:C, 3l1c:A, 1n6m:A, 2ncd:A, 3u06:A, 5w3d:A
52 3t0q:A 304 329 0.3500 0.3914 0.3617 2.35e-54
53 6bbn:E 378 335 0.3588 0.3228 0.3642 2.37e-54 2gry:A
54 3cnz:A 333 335 0.3618 0.3694 0.3672 2.55e-54 3cnz:B
55 3nwn:A 308 295 0.3324 0.3669 0.3831 1.45e-53
56 4etp:A 379 347 0.3647 0.3272 0.3573 1.03e-52 1f9t:A, 1f9u:A, 1f9v:A, 3kar:A
57 5xja:A 337 335 0.3559 0.3591 0.3612 5.59e-52 3edl:D, 2heh:A, 4ubf:B, 4ubf:C, 4ubf:D, 1v8k:A, 5xja:B, 5xjb:B, 4y05:A
58 4gkr:B 307 339 0.3735 0.4137 0.3746 5.73e-52 4gkr:A
59 6nje:A 297 329 0.3324 0.3805 0.3435 4.35e-51
60 3u06:B 344 328 0.3676 0.3634 0.3811 1.13e-48 3l1c:B, 1n6m:B
61 5nd4:C 337 351 0.3412 0.3442 0.3305 7.20e-48
62 5wdh:A 296 326 0.3265 0.3750 0.3405 6.72e-47
63 4h1g:A 670 284 0.3265 0.1657 0.3908 1.52e-44
64 3dcb:A 299 327 0.3088 0.3512 0.3211 3.24e-44 3dc4:A, 3dco:N, 3pxn:A
65 4ubf:A 309 334 0.3353 0.3689 0.3413 2.46e-43
66 1f9w:A 300 284 0.3088 0.3500 0.3697 3.42e-40 1f9w:B
67 5w3d:B 313 324 0.3324 0.3610 0.3488 6.77e-39
68 5nd7:C 300 337 0.3147 0.3567 0.3175 1.24e-38
69 5nd2:C 280 330 0.2882 0.3500 0.2970 5.82e-34
70 8bjs:A 343 380 0.2853 0.2828 0.2553 5.36e-26
71 6lkg:A 294 75 0.0647 0.0748 0.2933 0.042 6lkg:C, 6lkh:A, 6lkh:B, 6lkj:A, 6lkk:A
72 2atx:A 186 125 0.1059 0.1935 0.2880 0.20 2atx:B
73 8amq:A 464 32 0.0353 0.0259 0.3750 3.4 8amo:A, 8ckn:A
74 7lj3:0 285 54 0.0471 0.0561 0.2963 3.7 7lj3:z, 7lj3:5, 7lj3:6, 7lj3:8, 7lj3:9
75 8xvg:L 3485 52 0.0529 0.0052 0.3462 4.0 8xvv:L
76 7ktr:A 3042 52 0.0529 0.0059 0.3462 4.2
77 6nes:A 431 44 0.0471 0.0371 0.3636 7.4 6nes:B, 6net:A, 6net:B, 6neu:A, 6neu:B, 6nev:A, 6nev:B
78 1ksi:A 642 44 0.0441 0.0234 0.3409 7.5 1ksi:B, 1w2z:A, 1w2z:B, 1w2z:C, 1w2z:D
79 1vhd:A 361 118 0.0794 0.0748 0.2288 8.0 1o2d:A, 1o2d:B, 1vhd:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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