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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ETFEKQLKDLTSNVKSIQDNLLEEIITPNTKTEYLQRFLIDRFDKELFKKNVPIVSYEDIKPYLDRVVNGESSDVISART
ITGFLLSSGTSGGAQKMMPWNNKYLDNLTFIYDLRMQVITKHVKGVEEGKGMMFLFTKQESMTPSGLPARVATSSYFKSD
YFKNRPSNWYYSYTSPDEVILCPNNTESLYCHLLCGLVQRDEVVRTGSIFASVMVRAIEVLKNSWEELCSNIRSGHLSNW
VTDLGCQNSVSLVLGGPRPELADTIEEICNQNSWKGIVKRLWPNTKYIETVVTGSMGQYVPMLNYYCNDLPLVSTTYGSS
ETTFGINLDPLCKPEDVSYTFMPNMSYFEFIPMDGGDKNDVVDLEDVKLGCTYEPVVTNFAGLYRMRVGDIVLVTGFYNN
APQFKFVRRENVVLSIDSDKTNEEDLFKAVSQTSYADTSTFPGHYVVYLLSTCCLVMEESLDNVYKRCRFKDGSIGPLEI
RAKFFSI

The query sequence (length=487) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4epm:A 554 509 0.9877 0.8682 0.9450 0.0 4eq4:A, 4eq4:B, 4eql:A, 4eql:B, 4l39:A, 4l39:B, 6oms:A, 6oms:B
2 4ewv:B 492 510 0.8542 0.8455 0.8157 0.0 4ewv:A
3 5kod:D 566 500 0.5195 0.4470 0.5060 1.13e-176
4 7vka:A 595 519 0.5195 0.4252 0.4875 9.63e-176 5kod:A, 5kod:B, 5kod:C, 7vka:B
5 4b2g:B 572 513 0.5031 0.4283 0.4776 2.47e-172 4b2g:A
6 6e1q:A 569 507 0.5010 0.4288 0.4813 1.24e-168 6avh:A, 6avh:C, 6avh:D
7 7dk8:A 558 501 0.4846 0.4229 0.4711 2.31e-166
8 6avh:B 541 504 0.4846 0.4362 0.4683 2.87e-154
9 5ech:A 569 508 0.3717 0.3181 0.3563 2.61e-106 5ech:D, 5eci:A, 5eci:D, 5eck:A, 5eck:D, 5ecl:A, 5ecl:D, 5ecm:A, 5ecm:D, 5ecn:A, 5ecn:D, 5eco:A, 5eco:D, 5ecp:A, 5ecp:D, 5ecq:A, 5ecq:D, 5ecr:A, 5ecr:D, 4epl:A, 5gzz:A
10 4avn:A 420 115 0.0657 0.0762 0.2783 0.17 4avo:A, 4b4f:A, 4b4f:B
11 6o1x:A 354 92 0.0431 0.0593 0.2283 2.9 6o1w:A, 6o1w:B, 6o1y:A
12 3aex:A 351 52 0.0431 0.0598 0.4038 3.6 3aex:B, 3aey:A, 3aey:B, 1uim:A, 1uim:B, 1uin:A, 1uin:B, 1v7c:A, 1v7c:B, 1v7c:C, 1v7c:D
13 7pxc:E 483 96 0.0493 0.0497 0.2500 4.1 7px9:A, 7px9:B, 7px9:C, 7px9:E, 7px9:F, 7pxb:A, 7pxb:B, 7pxb:C, 7pxb:E, 7pxb:F, 7pxc:B, 7pxc:C, 7pxc:F, 7pxc:A, 7pxd:B, 7pxd:C, 7pxd:E, 7pxd:F, 7pxd:A
14 6x89:A7 109 30 0.0246 0.1101 0.4000 5.0
15 7cdw:A 683 94 0.0472 0.0337 0.2447 6.8 7cdw:B
16 4ngu:A 317 99 0.0513 0.0789 0.2525 7.6
17 3d31:A 348 49 0.0349 0.0489 0.3469 7.6 3d31:B
18 8c5s:A 924 78 0.0431 0.0227 0.2692 7.8 8ap1:A, 8att:A, 8atv:A, 8atw:A, 8c5u:A, 8q63:A, 6ymw:A
19 6ymv:A 887 80 0.0431 0.0237 0.2625 8.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218