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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ESVVDLRGMWIGLVLLNVFYLIVRIYEQVFGWRAGLDSFAPEFQTYWMSILWTEIPLELVSGLGLAGYLWKTRDRNVDAV
TPREEMRRLVVLVQWLVVYGIAIYWGASFFTEQDGTWHMTVIRDTDFTPSHIIEFYMSYPIYSVIAVGAFFYAKTRIPYF
AHGYSLAFLIVAIGPFMIIPNWMALGVFGVVLQILMRIHALVGKEGVKLLTE

The query sequence (length=212) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4pi0:C 217 217 1.0000 0.9770 0.9770 3.51e-152 4phz:C, 4phz:G, 4phz:K, 4pi0:G, 4pi0:K, 3rfr:C, 3rfr:G, 3rfr:K
2 7s4m:K 241 241 1.0000 0.8797 0.8797 2.12e-147 4pi2:C, 4pi2:G, 4pi2:K, 7s4m:G, 7s4m:C
3 3chx:C 159 159 0.6604 0.8805 0.8805 7.55e-105 3chx:G, 3chx:K
4 3rgb:C 213 191 0.5613 0.5587 0.6230 3.23e-85 3rgb:K, 3rgb:G
5 8oyi:C 236 179 0.5377 0.4831 0.6369 1.23e-81 8oyi:G, 8oyi:K, 7s4h:C, 7s4h:G, 7s4h:K, 7s4i:C, 7s4i:G, 7s4i:K, 7s4j:C, 7s4j:G, 7s4j:K, 7s4k:C, 7s4k:G, 7s4k:K, 8sqw:C, 8sqw:G, 8sqw:K, 8sr1:C, 8sr1:G, 8sr1:K, 8sr2:C, 8sr2:G, 8sr2:K, 8sr4:C, 8sr4:G, 8sr4:K, 7t4p:C, 7t4p:G, 7t4p:K
6 1yew:C 188 187 0.5142 0.5798 0.5829 1.78e-74 1yew:G, 1yew:K
7 7s4l:C 231 170 0.4953 0.4545 0.6176 5.42e-74 7s4l:H, 7s4l:I
8 6cxh:C 101 133 0.2217 0.4653 0.3534 1.10e-15
9 8ee7:A 456 103 0.1321 0.0614 0.2718 0.046 8ee4:A, 8ee4:B, 8ee4:C, 8ee4:D, 8ee4:E, 8ee4:F, 8ee7:B, 8eea:A, 8eea:B, 8eea:C, 8eea:D, 8eea:E, 8eea:F, 8sux:A, 8sux:B, 8sux:C, 8sux:D, 8sux:E, 8sux:F
10 7kgg:C 1020 58 0.0943 0.0196 0.3448 0.46 7kgh:C, 7kgi:A, 7kgi:C
11 2zx6:A 442 108 0.1226 0.0588 0.2407 0.67 1hl9:A, 1hl9:B, 1odu:A, 1odu:B, 2wsp:A, 2wsp:B, 2zwz:A, 2zwz:B, 2zx5:A, 2zx5:B, 2zx6:B, 2zx7:A, 2zx7:B, 2zx8:A, 2zx8:B, 2zx9:A, 2zx9:B, 2zxa:A, 2zxa:B, 2zxb:A, 2zxb:B, 2zxd:A, 2zxd:B
12 8wst:R 287 113 0.1274 0.0941 0.2389 1.3
13 7wf3:C 328 62 0.0896 0.0579 0.3065 1.7 2a79:A, 3eau:A, 3eb3:A, 3eb4:A, 6ebk:A, 6ebk:C, 6ebk:E, 6ebk:G, 6ebl:A, 6ebl:C, 6ebl:E, 6ebl:G, 7ej1:A, 7ej1:C, 7ej1:E, 7ej1:G, 7ej2:A, 7ej2:C, 7ej2:E, 7ej2:G, 1exb:A, 4jta:A, 4jta:P, 4jtc:A, 4jtc:G, 4jtd:A, 4jtd:G, 3lnm:A, 3lnm:C, 3lut:A, 1qrq:A, 1qrq:B, 1qrq:C, 1qrq:D, 2r9r:A, 2r9r:G, 7sit:A, 7sit:C, 7siz:A, 7siz:C, 7wf3:G, 7wf3:I, 7wf3:M, 7wf4:G, 7wf4:I, 7wf4:M, 7wf4:o, 5wie:A, 5wie:G, 1zsx:A
14 8wgh:L 162 53 0.0896 0.1173 0.3585 3.5
15 7sk7:A 267 130 0.1509 0.1199 0.2462 4.6

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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