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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ERPPVFWLQGQGCTGCSVTLLNSVHPSIADVLLKVISLEFHPTVMAWEGEHAIEHMRKVAEKFKGKFFLVIEGSVPVEAD
GKYCIIGEANHHEISMVDALKEFGPNAAAVLAVGTCAAYGGIPAAEGSETGATAVSKFLGDNGIKTPVVNIPGCPPHPDW
IVGTVVLALDAIKKNGLEGGLAEVVKVLDSDGRPTPFFGRNIHENCPYLDKYDEGVMSATFTDKVGCRYDLGCKGPMTMA
DCFERKWNGGVNWCVQNAVCIGCVEPDFPDGKSPFYQA

The query sequence (length=278) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5jsh:A 283 278 1.0000 0.9823 1.0000 0.0 5jsk:A, 5jsu:A, 5jsy:A, 5jt1:A, 6rtp:A, 6ru9:A, 6ruc:A, 2wpn:A, 6z7r:A, 6z7r:C, 6z8j:A, 6z8j:C, 6z8m:A, 6z8o:A, 6z8o:C, 6z9g:A, 6z9g:C, 6z9g:E, 6z9g:G, 6z9o:A, 6za1:A, 3ze6:A, 3ze7:A, 3ze8:A, 3ze9:A, 3zea:A
2 4kl8:S 279 283 0.6151 0.6129 0.6042 6.05e-127 1cc1:S, 4kl8:T, 4kn9:S, 4kn9:T, 4ko1:S, 4ko1:T, 4ko2:S, 4ko2:T, 4ko3:S, 4ko3:T, 4ko4:S, 4ko4:T
3 1frv:A 262 283 0.4317 0.4580 0.4240 2.37e-61 1frv:C, 2frv:S, 2frv:A, 2frv:C, 2frv:E, 2frv:G, 2frv:I, 1yq9:A, 1yq9:B
4 1h2a:S 267 282 0.4137 0.4307 0.4078 5.09e-57 1h2r:S, 4u9h:S, 4u9i:S, 1ubh:S, 1ubj:S, 1ubk:S, 1ubl:S, 1ubm:S, 1ubo:S, 1ubr:S, 1ubt:S, 1ubu:S, 8w6x:S, 1wuh:S, 1wui:S, 1wuj:S, 1wuk:S, 1wul:S, 5xle:S, 5xlf:S, 5xlg:S, 5xlh:S, 5y4n:S
5 3ayx:B 273 283 0.3813 0.3883 0.3746 4.75e-54 3ayx:D, 3ayz:B, 3ayz:D, 5d51:S, 4iub:S, 4iuc:S, 4iud:S, 5mdj:S, 5mdk:S, 5mdl:S, 7odg:S, 7odh:S, 8pou:S, 8pov:S, 8pow:S, 8pox:S, 8poz:S, 3rgw:S, 4ttt:S, 5y34:B, 5y34:D
6 3myr:C 269 283 0.3813 0.3941 0.3746 9.98e-52 3myr:A, 3myr:E, 3myr:G
7 1e3d:A 262 282 0.3993 0.4237 0.3936 7.37e-50 1e3d:C
8 4c3o:B 263 284 0.3633 0.3840 0.3556 1.45e-47 4c3o:D, 4c3o:F
9 4urh:C 264 282 0.3705 0.3902 0.3652 2.43e-46 3cur:A, 3cur:B, 3cur:C, 3cus:A, 3cus:B, 3cus:C, 1frf:S, 3h3x:A, 3h3x:B, 3h3x:C, 4ucq:A, 4ucq:B, 4ucq:C, 4ucw:A, 4ucw:B, 4ucw:C, 4ucx:A, 4ucx:B, 4ucx:C, 4ud2:A, 4ud2:B, 4ud2:C, 4ud6:A, 4ud6:B, 4ud6:C, 4ue2:A, 4ue2:B, 4ue2:C, 4ue6:A, 4ue6:B, 4ue6:C, 4ueq:A, 4ueq:B, 4ueq:C, 4ueq:D, 4ueq:E, 4ueq:F, 4uew:A, 4uew:B, 4uew:C, 4upe:A, 4upe:B, 4upe:C, 4upv:A, 4upv:B, 4uql:A, 4uql:B, 4uqp:A, 4uqp:B, 4urh:A, 4urh:B, 1yqw:A, 1yqw:B, 1yqw:C, 1yrq:A, 1yrq:B, 1yrq:C, 1yrq:D, 1yrq:F, 1yrq:G
10 4gd3:S 304 280 0.3309 0.3026 0.3286 3.45e-46 5a4f:S, 5a4f:T, 5a4i:S, 5a4i:T, 5a4m:S, 5a4m:T, 5adu:S, 5adu:T, 6fpi:S, 6fpi:T, 6fpo:S, 6fpo:T, 6fpw:S, 6fpw:T, 6g7r:S, 6g7r:T, 6g94:S, 6g94:T, 6g94:Q, 6g94:R, 6gal:S, 6gal:T, 4gd3:T, 4gd3:Q, 4gd3:R, 5jrd:S, 5jrd:T, 5lmm:S, 5lmm:T, 5lry:S, 5lry:T, 6rp2:S, 6rp2:T, 4ue3:SSS, 4ue3:TTT, 3uqy:S, 3uqy:T, 3usc:S, 3usc:T, 3use:S, 3use:T
11 5aa5:A 345 289 0.3453 0.2783 0.3322 2.80e-42 5aa5:B, 5aa5:D, 5aa5:F, 5aa5:H, 5aa5:M
12 5xvd:S 269 272 0.3561 0.3680 0.3640 1.61e-37 6ehq:S, 6ehq:T, 6ehs:S, 6ehs:T, 6en9:S, 6en9:T, 6g7m:S, 6g7m:T, 6gam:S, 6gam:T, 6gan:S, 6gan:T, 7nem:S, 7nem:T, 6syo:SSS, 6syo:TTT, 6syx:SSS, 6syx:TTT, 6szd:SSS, 6szd:TTT, 6szk:SSS, 6szk:TTT, 7vxq:B, 7vxq:D, 5xvb:S, 5xvb:T, 5xvc:S, 5xvc:T, 5xvd:T
13 8dqv:B 322 279 0.2986 0.2578 0.2975 1.24e-32 8dqv:D, 7utd:B, 7utd:D, 7utd:F, 7utd:H, 7utd:J, 7utd:L, 7utd:N, 7utd:P, 7uur:D, 7uur:G, 7uus:B, 7uus:D, 7uus:F, 7uus:H, 7uus:J, 7uus:L, 7uus:N, 7uus:P
14 4omf:G 231 171 0.1547 0.1861 0.2515 4.99e-06 4ci0:B, 3zfs:B
15 6qgr:G 253 87 0.0971 0.1067 0.3103 8.31e-05 6qgt:G, 6qii:G
16 6cfw:J 143 122 0.1259 0.2448 0.2869 3.79e-04
17 7q5y:F 135 126 0.1187 0.2444 0.2619 7.35e-04 7q5y:L, 7q5y:R, 7q5y:X
18 6nbq:K 212 150 0.1367 0.1792 0.2533 0.001 6hum:K, 6khi:K, 6khj:K, 6l7o:K, 6l7p:K, 6nbx:K, 6nby:K, 6tjv:K
19 5odc:E 298 156 0.1475 0.1376 0.2628 0.015 5odc:K, 5odh:E, 5odh:K, 5odi:E, 5odi:K, 5odq:E, 5odq:K, 5odr:E, 5odr:K
20 8e9g:B 183 137 0.1151 0.1749 0.2336 0.053 8e9h:B, 8e9i:B
21 3e7f:B 263 99 0.1007 0.1065 0.2828 0.099 3e7f:A, 3eb9:A, 3eb9:B, 2j0e:A, 2j0e:B
22 7awt:B 141 83 0.0899 0.1773 0.3012 0.13
23 7wfg:K 167 67 0.0755 0.1257 0.3134 0.17 7wg5:K
24 7p69:B 169 66 0.0827 0.1361 0.3485 0.23 7nz1:B, 7p7e:B, 7zc5:B, 7zci:B
25 7tgh:S7 162 128 0.1115 0.1914 0.2422 0.24 8b6f:AT, 8bqs:AT, 8gym:s7, 8gym:S7, 8gzu:s7, 8gzu:S7
26 7z7s:B 213 66 0.0827 0.1080 0.3485 0.26 7nyr:B, 7nyu:B, 7nyv:B, 7p61:B, 7p62:B, 7p63:B, 7p64:B, 7p7c:B, 7p7j:B, 7p7k:B, 7p7l:B, 7p7m:B, 7z7r:B, 7z7t:B, 7z7v:B, 7z80:B, 7z83:B, 7z84:B
27 5xf9:C 178 62 0.0576 0.0899 0.2581 0.64 5xf9:G, 5xfa:C, 5xfa:G
28 6u8y:J 177 172 0.1295 0.2034 0.2093 1.2 6u8y:j
29 8q0j:B 158 124 0.0935 0.1646 0.2097 1.7 7ak5:B, 7ak6:B, 7b93:B, 8c2s:B, 8ca3:B, 8ca5:B, 7dgq:D, 7dgr:D, 7dgs:D, 7dgz:D, 7dh0:D, 7dkf:D2, 6g2j:B, 6g72:B, 5gpn:a, 5gup:I, 8iao:B, 8iap:B, 8ib4:B, 8ib5:B, 8ib9:B, 8iba:B, 8ibd:B, 8ibe:B, 8ic2:B, 8ic3:B, 5lc5:B, 5ldw:B, 5ldx:B, 5lnk:6, 5o31:B, 8olt:B, 8om1:B, 7psa:B, 8pw5:6, 8pw6:6, 8pw7:6, 8q0a:B, 8q0f:B, 8q0m:B, 8q0o:B, 8q0q:B, 8q1p:B, 8q1u:B, 8q1y:B, 8q25:B, 8q45:B, 8q46:B, 8q47:B, 8q48:B, 8q49:B, 8q4a:B, 6q9d:S7, 6qa9:S7, 6qbx:S7, 6qc2:S7, 6qc3:S7, 6qc4:S7, 6qc5:S7, 6qc6:S7, 6qc7:S7, 6qc8:S7, 6qc9:S7, 6qca:S7, 6qcf:S7, 7qsd:B, 7qsk:B, 7qsl:B, 7qsm:B, 7qsn:B, 7qso:B, 7r41:B, 7r42:B, 7r43:B, 7r44:B, 7r45:B, 7r46:B, 7r47:B, 7r48:B, 7r4c:B, 7r4d:B, 7r4f:B, 7r4g:B, 8rgp:6, 8rgq:6, 8rgr:6, 8rgt:6, 8ud1:1B, 8ueo:1B, 8uep:1B, 8ueq:1B, 8uer:1B, 8ues:1B, 8uet:1B, 8ueu:1B, 8uev:1B, 8uew:1B, 8uex:1B, 8uey:1B, 8uez:1B, 8ugh:1B, 8ugi:1B, 8ugj:1B, 8ugn:1B, 8ugn:5B, 8ugp:1B, 8ugr:1B, 8ugr:5B, 7v2c:C, 7v2d:C, 7v2e:C, 7v2f:C, 7v2h:C, 7v2k:C, 7v2r:C, 7v30:C, 7v31:C, 7v32:C, 7v33:C, 7v3m:C, 7vb7:C, 7vbn:C, 7vbz:C, 7vwj:C, 7vxp:C, 7vxu:C, 7vy8:C, 7vya:C, 7vyf:C, 7vyh:C, 7vyn:C, 7vz1:C, 7vzv:C, 7vzw:C, 7w00:C, 7w0h:C, 7w0r:C, 7w0y:C, 7w1o:C, 7w1p:C, 7w1t:C, 7w1u:C, 7w1v:C, 7w1z:C, 7w20:C, 7w2k:C, 7w2l:C, 7w2r:C, 7w2u:C, 7w2y:C, 7w31:C, 7w32:C, 7w35:C, 7w4c:C, 7w4d:C, 7w4e:C, 7w4f:C, 7w4g:C, 7w4j:C, 7w4k:C, 7w4l:C, 7w4m:C, 7w4n:C, 7w4q:C, 5xtb:C, 5xtd:C, 5xth:C, 5xti:C, 5xti:BC, 7zd6:6, 7zdh:6, 7zdj:6, 7zdm:6, 7zdp:6, 7zeb:6, 6zk9:6, 6zkc:6, 6zkd:6, 6zke:6, 6zkf:6, 6zkg:6, 6zkh:6, 6zki:6, 6zkj:6, 6zkk:6, 6zkl:6, 6zkm:6, 6zkn:6, 6zko:6, 6zkp:6, 6zkq:6, 6zkr:6, 6zks:6, 6zkt:6, 6zku:6, 6zkv:6, 6zr2:B, 6ztq:B
30 6i0d:6 166 117 0.1043 0.1747 0.2479 2.1 4hea:6, 4hea:G, 6i0d:G, 6i1p:6, 6i1p:G, 3i9v:6, 3i9v:F, 3ias:6, 3ias:F, 3ias:O, 3ias:X, 3m9s:6, 3m9s:F, 6q8o:6, 6q8o:G, 6q8w:6, 6q8w:G, 6q8x:6, 6q8x:G, 6y11:6, 6y11:G, 6ziy:6, 6zjl:6, 6zjn:6, 6zjy:6
31 4w8h:A 127 60 0.0647 0.1417 0.3000 3.2
32 8b9z:B 182 126 0.1079 0.1648 0.2381 3.5 8ba0:B, 8esw:S7, 8esz:S7
33 8iuf:S7 201 125 0.1115 0.1542 0.2480 3.6 8j9h:S7, 8j9i:S7, 8j9j:S7
34 5n2n:A 149 69 0.0612 0.1141 0.2464 4.1 3mmn:A
35 7w1y:6 716 97 0.0899 0.0349 0.2577 4.4 7w1y:E
36 6xtx:6 679 97 0.0899 0.0368 0.2577 4.4 8b9d:6, 7pfo:6, 7plo:6, 6xty:6
37 2q3o:B 367 60 0.0719 0.0545 0.3333 4.4 2g5w:A, 2g5w:B, 2q3o:A, 1q45:A, 1q45:B
38 2fug:6 144 98 0.0863 0.1667 0.2449 4.8 2fug:F, 2fug:O, 2fug:X, 3iam:6, 3iam:F, 2ybb:6
39 2glf:A 450 28 0.0360 0.0222 0.3571 5.1 2glf:B, 2glf:C, 2glf:D
40 8ouw:6 707 78 0.0755 0.0297 0.2692 5.6
41 3tzc:A 224 16 0.0396 0.0491 0.6875 6.0
42 3op4:A 247 16 0.0396 0.0445 0.6875 6.4 4i08:A, 4i08:B, 3op4:B, 3rsh:A, 3rsh:B, 4wk6:A, 4wk6:B, 4wk6:C, 4wk6:D
43 6ftg:x 426 43 0.0612 0.0399 0.3953 7.2 8btk:SX, 6fti:x, 6ftj:x, 3j7q:1, 3j7r:1, 3jc2:1, 8oj0:1, 8oj8:1, 6r7q:XX, 6w6l:1, 7zl3:A
44 8bf9:C 385 43 0.0612 0.0442 0.3953 7.4 6z3t:A
45 8b6l:A 425 43 0.0612 0.0400 0.3953 7.6
46 7sa3:B 450 116 0.0971 0.0600 0.2328 8.8
47 2wwb:A 476 43 0.0612 0.0357 0.3953 9.0 8b5l:s, 8b6c:K, 4cg6:A, 8dnx:A, 8dny:A, 8dnz:A, 8do0:A, 8do1:A, 8do2:A, 8do3:A, 8rjb:1, 8rjc:1, 8rjd:1, 7tm3:1, 7tut:1
48 8eqm:B 483 116 0.0971 0.0559 0.2328 9.2 8eqm:b

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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