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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EQTPQICVVGSGPAGFYTAQHLLKHHSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARSDRCAFYGNVEVG
RDVTVQELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARI
LLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLPGTRPMLDPADFLGLQDRIKEAARPRK
RLMELLLRTATEKPGVEEAARRASASRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVTRLEGIGEATRAVPTGDVEDLPCG
LVLSSIGYKSRPIDPSVPFDPKLGVVPNMEGRVVDVPGLYCSGWVKRGPTGVITTTMTDSFLTGQILLQDLKAGHLPSGP
RPGSAFIKALLDSRGVWPVSFSDWEKLDAEEVSRGQASGKPREKLLDPQEMLRLLGH

The query sequence (length=457) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1e6e:A 457 457 1.0000 1.0000 1.0000 0.0 1cjc:A, 1e1k:A, 1e1l:A, 1e1m:A, 1e1n:A, 1e6e:C
2 1lqt:B 454 463 0.4092 0.4119 0.4039 5.69e-96 2c7g:A, 1lqt:A, 1lqu:A, 1lqu:B
3 4ylf:B 468 166 0.1225 0.1197 0.3373 1.41e-14 4ylf:D, 4yry:B, 4yry:D
4 5jca:L 471 161 0.1007 0.0977 0.2857 2.39e-11 5jfc:L
5 7mfm:I 490 120 0.0766 0.0714 0.2917 1.83e-09 7mfm:J, 7mft:I
6 5vj7:A 462 233 0.1400 0.1385 0.2747 1.11e-08
7 8oh5:C 1172 120 0.0810 0.0316 0.3083 9.97e-08 8oh5:F, 8oh5:I, 8oh5:L, 8oh9:C, 8oh9:F, 8oh9:I, 8oh9:L
8 6s6t:E 472 138 0.0766 0.0742 0.2536 8.75e-04 6s6s:G, 6s6s:E, 6s6s:F, 6s6s:H, 6s6t:F, 6s6t:G, 6s6u:G, 6s6u:H, 6s6u:I, 6s6u:J, 6s6x:G, 6s6x:H, 6s6x:I, 6s6x:J, 6s6x:K, 6s6x:L, 2vdc:G, 2vdc:H, 2vdc:I, 2vdc:J, 2vdc:K, 2vdc:L
9 1f8w:A 447 190 0.0985 0.1007 0.2368 0.003 1joa:A, 1nhp:A, 1nhq:A, 1nhr:A, 1nhs:A, 1npx:A, 2npx:A
10 2gv8:A 442 42 0.0284 0.0294 0.3095 1.8 2gv8:B, 2gvc:A, 2gvc:B, 2gvc:D, 2gvc:E, 1vqw:A, 1vqw:B
11 6ppr:B 760 45 0.0350 0.0211 0.3556 2.1 6ppu:B
12 8aq8:AAA 344 34 0.0306 0.0407 0.4118 5.6 8aq8:BBB, 8aq8:CCC, 8aq8:DDD
13 4emj:A 406 137 0.0613 0.0690 0.2044 7.7 3ef6:A, 4emi:A
14 1vdc:A 322 66 0.0438 0.0621 0.3030 7.8
15 1iug:A 348 53 0.0306 0.0402 0.2642 8.8 1iug:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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