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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EQETRLRFVSSEWRSGRPQPPERRIPICFPNITLQMMKLTPEQMDQVKETGWLREVAFKTTPDVTKLEIAAFLQSVYGMN
VERVSTINYLGRRRLAISRNGKRLWWREDDWKKAYVIFRPPAGQEHLLTRQQRPVIEQIREAARAPRLPPRPYPWERR

The query sequence (length=158) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7pkt:r 158 158 1.0000 1.0000 1.0000 3.34e-114
2 8a22:Ar 155 117 0.4367 0.4452 0.5897 2.48e-45 8apn:Ar, 8apo:Ar
3 6xyw:At 105 95 0.2089 0.3143 0.3474 5.38e-12
4 6spf:T 94 71 0.1709 0.2872 0.3803 5.07e-09 8cd1:T, 6spb:T, 6spd:T, 6spg:T, 7unr:V, 7unu:V, 7unv:V, 7unw:V
5 7z20:t 101 67 0.1582 0.2475 0.3731 4.64e-07 8a3l:s, 7abz:T, 7ac7:T, 7acj:T, 7acr:T, 5ady:T, 5afi:T, 8akn:s, 8am9:s, 8ana:s, 8ap4:s, 9ax7:s, 9ax8:T, 8aye:s, 8b0x:s, 7b5k:T, 8b7y:b, 8bf7:Q, 8bge:Q, 8bgh:Q, 8bh4:Q, 8bhj:Q, 8bhl:Q, 8bhn:Q, 8bhp:Q, 8bil:Q, 8bim:Q, 7bl2:T, 7bl3:T, 7bl4:T, 7bl5:T, 7bl6:T, 6bu8:22, 7bv8:U, 6by1:CT, 6by1:DT, 6c4i:U, 8c8x:T, 8c8y:T, 8c8z:T, 8c90:T, 8c91:T, 8c92:T, 8c93:T, 8c97:T, 8c98:T, 8cam:s, 8ceu:s, 8cgd:s, 8cgk:s, 8cgv:s, 9cg5:s, 9cg6:s, 9cg7:s, 9cl9:T, 7cpj:T, 4csu:T, 7d6z:Z, 7d80:W, 6dnc:X, 8eiu:s, 8ekc:V, 8emm:s, 6enf:T, 6enj:T, 6enu:T, 9fbv:s, 8fiz:DA, 8fto:s, 8fzd:V, 8fze:V, 8fzf:V, 8fzg:V, 8fzh:V, 8fzi:V, 8fzj:V, 8g2u:T, 8g31:T, 8g34:T, 8g38:T, 8g6w:s, 8g6x:s, 8g6y:s, 8g7p:V, 8g7q:V, 8g7r:V, 8g7s:V, 5gad:U, 5gae:U, 5gaf:U, 5gag:U, 5gah:U, 6gbz:T, 6gc0:T, 6gc4:T, 6gc6:T, 6gc7:T, 6gc8:T, 6gwt:T, 6gxm:T, 6gxn:T, 6gxo:T, 6gxp:T, 6h4n:T, 5h5u:U, 6h58:T, 6h58:TT, 6hrm:T, 8hsp:s, 8htz:s, 8hu1:s, 6i0y:T, 6i7v:DU, 6i7v:CU, 8ifb:s, 8ifc:s, 5iqr:T, 5it8:CU, 5it8:DU, 8j1z:s, 3j5l:T, 5j5b:CU, 5j5b:DU, 3j7z:T, 5j7l:CU, 5j7l:DU, 3j8g:T, 5j88:CU, 5j88:DU, 5j8a:CU, 5j8a:DU, 3j9y:T, 5j91:CU, 5j91:DU, 3jbu:t, 3jbv:t, 3jcd:T, 3jce:T, 3jcj:S, 3jcn:T, 5jc9:CU, 5jc9:DU, 7jss:t, 7jsw:t, 7jsz:t, 5jte:BT, 7jt1:t, 7jt2:t, 7jt3:t, 5ju8:BT, 7k00:s, 7k50:t, 7k51:t, 7k52:t, 7k53:t, 7k54:t, 7k55:t, 5kcr:1X, 5kcs:1X, 5kps:T, 5kpv:S, 5kpw:S, 5kpx:S, 5l3p:X, 6lkq:b, 7lv0:t, 7lvk:b, 5lza:T, 5lzb:T, 5lzc:T, 5lzd:T, 5lze:T, 5lzf:T, 7m5d:T, 5mdv:T, 5mdw:T, 5mdy:T, 5mdz:T, 5mgp:T, 7n1p:LW, 7n2c:LW, 7n2u:LW, 7n2v:LW, 7n30:LW, 7n31:LW, 7nbu:s, 5nco:U, 5np6:r, 7nso:T, 7nsp:T, 7nsq:T, 5nwy:g, 7nwt:T, 7nww:S, 7o19:BT, 7o1a:BT, 7o1c:BT, 5o2r:T, 6o9k:T, 7ode:b, 6ofx:t, 6og7:t, 6ogf:t, 6ogg:t, 6ogi:t, 7oif:S, 7oig:S, 7oii:S, 7oiz:s, 7oj0:s, 6om6:T, 6ore:T, 6orl:T, 6osk:T, 6osq:T, 6ost:T, 6ot3:T, 7ot5:S, 7otc:T, 6ouo:T, 8p16:T, 8p17:T, 8p18:T, 7p3k:s, 8peg:w, 8phj:s, 6pj6:b, 7pjs:T, 7pjt:T, 7pju:T, 7pjv:T, 7pjw:T, 7pjx:T, 7pjy:T, 7pjz:T, 8pkl:w, 8pva:s, 7q4k:BT, 8q4f:s, 6q97:T, 6q98:T, 6q9a:T, 8qbt:T, 6qdw:t, 7qg8:g, 7qgh:g, 7qgn:g, 7qgr:g, 8qk7:T, 8qoa:s, 7qq3:b, 6qul:U, 8r6c:s, 8r8m:s, 8rpy:T, 8rpz:T, 8rq0:T, 8rq2:T, 6s0k:U, 7s1g:b, 7s1h:b, 7s1i:b, 7s1j:b, 7s1k:b, 7sa4:T, 7ss9:t, 7ssd:t, 7ssl:t, 7ssn:t, 7sso:t, 7ssw:t, 7st2:t, 7st6:t, 7st7:t, 8syl:V, 6szs:T, 8t5d:T, 8t5h:T, 6tbv:L231, 6tc3:L231, 7tos:L23, 4u1u:BT, 4u1u:DT, 4u1v:BT, 4u1v:DT, 4u20:BT, 4u20:DT, 4u24:BT, 4u24:DT, 4u25:BT, 4u25:DT, 4u26:BT, 4u26:DT, 4u27:BT, 4u27:DT, 5u4i:U, 6u48:CU, 5u9f:22, 5u9g:22, 7ug7:LW, 7uph:s, 8upo:2, 8upr:2, 8uql:2, 8uqm:2, 8uqp:2, 8ur0:2, 8urh:2, 8uri:2, 8urx:2, 8ury:2, 4uy8:T, 5uyk:22, 5uyl:22, 5uym:22, 5uyn:22, 5uyp:22, 5uyq:22, 4v4v:BR, 4v4w:BR, 4v50:BT, 4v50:DT, 4v52:BT, 4v52:DT, 4v53:BT, 4v53:DT, 4v54:BT, 4v54:DT, 4v55:BT, 4v55:DT, 4v56:BT, 4v56:DT, 4v57:BT, 4v57:DT, 4v5h:BT, 4v5y:BT, 4v5y:DT, 4v64:BT, 4v64:DT, 4v69:BT, 4v6c:BT, 4v6c:DT, 4v6d:BT, 4v6d:DT, 4v6e:BT, 4v6e:DT, 4v6t:BT, 4v6y:BT, 4v6z:BT, 4v70:BT, 4v71:BT, 4v72:BT, 4v73:BT, 4v74:BT, 4v75:BT, 4v76:BT, 4v77:BT, 4v78:BT, 4v79:BT, 4v7a:BT, 4v7b:BT, 4v7c:BV, 4v7d:AW, 4v7i:AT, 4v7s:BT, 4v7s:DT, 4v7t:BT, 4v7t:DT, 4v7u:BT, 4v7u:DT, 4v7v:BT, 4v7v:DT, 4v85:BX, 4v89:BX, 4v9c:BT, 4v9c:DT, 4v9d:CT, 4v9d:DT, 4v9o:AT, 4v9o:CT, 4v9o:ET, 4v9o:GT, 4v9p:AT, 4v9p:CT, 4v9p:ET, 4v9p:GT, 8vs9:L23, 8vsa:L23, 6vu3:2, 6vwl:R, 6vwm:R, 6vwn:R, 6vyq:2, 6vyr:2, 6vys:2, 6vyt:2, 6vyu:2, 6vyw:2, 6vyx:2, 6vyy:2, 6vyz:2, 6vz2:2, 6vz3:2, 6vz5:2, 6vz7:2, 6vzj:2, 8w51:U, 5wdt:T, 6wd0:t, 6wd1:t, 6wd2:t, 6wd3:t, 6wd4:t, 6wd5:t, 6wd6:t, 6wd7:t, 6wd8:t, 6wd9:t, 6wda:t, 6wdb:t, 6wdc:t, 6wdd:t, 6wde:t, 6wdf:t, 6wdg:t, 6wdh:t, 6wdi:t, 6wdj:t, 6wdk:t, 6wdl:t, 6wdm:t, 5we4:T, 5we6:T, 4wf1:BT, 4wf1:DT, 5wf0:T, 5wfk:T, 5wfs:T, 6wnt:t, 6wnv:t, 6wnw:t, 4woi:BT, 4woi:CT, 4www:RT, 4www:YT, 6x6t:2, 6x7f:2, 6x7k:2, 6x9q:2, 6xdq:2, 6xdr:2, 6xgf:2, 6xii:2, 6xij:2, 6xz7:T, 6xza:T2, 6xzb:T2, 6y69:T, 7y7c:s, 7y7d:s, 7y7e:s, 7y7f:s, 7y7g:s, 7y7h:s, 4ybb:CU, 4ybb:DU, 7yla:b, 6ys3:t, 6ysr:T, 6yss:T, 6yst:T, 6ysu:T, 7zod:t, 7zp8:t, 6ztj:BU, 6ztl:BU, 6ztm:BU, 6ztn:BU, 6zto:BU, 6ztp:BU, 7zta:L231, 6zu1:BU
6 3j45:T 100 64 0.1519 0.2400 0.3750 8.82e-07 5aka:T, 3bbx:T, 8c9a:T, 2j28:T, 3j46:T, 3j9z:LR, 3ja1:LV, 6o9j:T, 4v4h:BT, 4v4h:DT, 4v4q:BT, 4v4q:DT, 4v5b:AT, 4v5b:CT, 4v65:BM, 4v66:BM, 4v6k:AU, 4v6l:BU, 4v6m:BT, 4v6n:AV, 4v6o:BV, 4v6p:BV, 4v6q:BV, 4v6r:BV, 4v6s:AV, 4v6v:BX, 7zq5:t, 7zq6:t
7 6yhs:P 92 69 0.1582 0.2717 0.3623 0.002 7m4v:S, 7m4w:S, 7m4x:S, 7m4y:S, 7m4z:S, 7ryf:S, 7ryg:S, 7ryh:S, 7uvv:S, 7uvw:S, 7uvx:S, 7uvy:S, 7uvz:S, 7uw1:S, 6v39:S, 6v3a:S, 6v3b:S, 6v3d:S, 6ysi:P
8 6z1p:Ax 132 44 0.0949 0.1136 0.3409 0.003
9 7a0r:Q 93 69 0.1582 0.2688 0.3623 0.026 7a0s:Q, 7a18:Q, 3cf5:Q, 2d3o:R, 3dll:Q, 5dm6:Q, 5dm7:Q, 4io9:Q, 4ioa:Q, 4ioc:Q, 5jvg:Q, 5jvh:Q, 3pio:Q, 3pip:Q, 4u67:Q, 4v4g:BU, 4v4g:DU, 4v4g:FU, 4v4g:HU, 4v4g:JU, 4wfn:Q, 1xbp:R, 2zjp:Q, 2zjq:Q, 2zjr:Q
10 3j3v:T 95 56 0.0886 0.1474 0.2500 0.35 7aqc:h, 7aqd:h, 7as8:X, 7as9:X, 8buu:T, 6ha1:T, 6ha8:T, 6htq:T, 3j3w:T, 3j9w:BW, 5njt:m, 7o5b:s, 7ope:X, 6ppf:T, 6ppk:T, 6pvk:T, 8qcq:T, 7qgu:T, 7qh4:T, 8qpp:s, 7qv1:T, 7qv2:T, 7qv3:T, 8r55:s, 8s1p:T, 8s1u:T, 7s9u:T, 7sae:T, 6tnn:m, 6tpq:m
11 4wsi:A 372 76 0.1456 0.0618 0.3026 0.86 7m4r:A, 7ntj:B, 7ntj:A, 7ntk:A, 7ntk:D, 7ntk:B, 7ntk:F, 7qcs:A, 7qcs:B, 4uu5:A, 4wsi:B
12 9c4g:s 95 47 0.0949 0.1579 0.3191 1.1 8crx:s, 8cvm:s
13 6dzi:U 97 46 0.0886 0.1443 0.3043 1.6 6dzp:U, 8fr8:Z, 8kab:U, 5o60:U, 5o61:U, 7s0s:V, 8v9j:V, 8v9k:V, 8v9l:V, 8whx:W, 8why:W, 8wi7:W, 8wi8:W, 8wib:W, 8wic:W, 7xam:U, 5xym:T, 8xz3:U, 7y41:U, 5zeb:U, 5zep:U, 5zet:U
14 7w6x:A 447 44 0.1013 0.0358 0.3636 1.8
15 7f0d:T 98 58 0.1076 0.1735 0.2931 2.7 7kgb:T, 7msc:T, 7msh:T, 7msm:T, 7msz:T, 7mt2:T, 7mt3:T, 7mt7:T, 7sfr:T, 5v7q:T, 5v93:T
16 1k83:A 1366 54 0.0886 0.0102 0.2593 3.2 1twa:A, 1twc:A, 1twg:A, 1twh:A
17 1oiz:A 265 38 0.0949 0.0566 0.3947 3.4 5mue:A, 5mug:A, 1oip:A, 1oiz:B, 1r5l:A, 3w67:A, 3w67:B, 3w67:C, 3w67:D, 3w68:A, 3w68:B, 3w68:D, 6zpd:A
18 1kat:V 99 32 0.0633 0.1010 0.3125 3.8 6d3o:A, 6d3o:B, 4glu:D, 1kat:W, 4kzn:A, 3qtk:A, 3qtk:D, 3qtk:F, 6v7k:B, 1vpp:V, 1vpp:W, 6z13:W, 6z3f:W, 6zbr:W, 6zcd:W
19 3w68:C 252 38 0.0949 0.0595 0.3947 4.2
20 1o5i:B 234 60 0.0949 0.0641 0.2500 6.4
21 8r8r:A 1188 59 0.0949 0.0126 0.2542 7.1
22 7s4o:A 170 41 0.0696 0.0647 0.2683 7.5 7s4o:B, 7s51:A, 7s51:B, 7t8y:A, 7t8z:A, 8t8g:A, 7v6k:A, 7v6k:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218