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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EPLSIVYPIPRNKLTPYRAVIIMRLIILGLFFHYRITNPVDSAFGLWLTSVICEIWFAFSWVLDQFPKWKPVNRETFIER
LSARYEREGEPSQLAAVDFFVSTVDPLKEPPLITANTVLSILAVDYPVDKVSCYVSDDGAAMLTFESLVETAEFARKWVP
FCKKFSIEPRAPEFYFSQKIDYLKDKVQPSFVKERRAMKRDYEEYKVRVNALVAKAQKTPDEGWTMQDGTPWPGNNTRDH
PGMIQVFLGNTGARDIEGNELPRLVYVSREKRPGYQHHKKAGAENALVRVSAVLTNAPYILNLDCDHYVNNSKAVREAMC
ILMDPQVGRDVCYVQFPQRFDGIDRSDRYANRNIVFFDVNMKGLDGIQGPMYVGTGCVFNRQALYGYGPPSMPSQLSFEK
TFGLSPVFIESTLMENGGVPESANSSTLIKEAIHVIGCGFEEKTEWGKEIGWIYGSVTEDILSGFKMHCRGWRSIYCMPV
RPAFKGSAPINLSDRLHQVLRWALGSVEIFFSRHCPFWYGYGGGRLKWLQRLAYINTIVYPFTSLPLIAYCTIPAVCLLT
GKFIIPTLSNLASMLFLGLFISIIVTAVLELRWSGVSIEDLWRNEQFWVIGGVSAHLFAVFQGFLKMLAGVKWTTLLIPP
TTLLIINIVGVVAGFSDALNKGYEAWGPLFGKVFFAFWVILHLYPFLKGLMGRQNRTPTIVVLWSVLLTSVFSLVWVKIN

The query sequence (length=720) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8g27:I 720 720 0.9972 0.9972 0.9972 0.0 8g27:C, 8g27:D, 8g2j:C, 8g2j:D, 8g2j:I, 6wlb:A, 6wlb:C, 6wlb:B
2 7d5k:A 727 724 0.7819 0.7744 0.7776 0.0 7d5k:B, 7d5k:C
3 7ck2:A 352 387 0.4069 0.8324 0.7571 0.0 7ck2:B
4 4hg6:A 747 337 0.1083 0.1044 0.2315 3.43e-08 5eiy:A, 5ej1:A, 5ejz:A, 4p00:A, 4p02:A
5 6ai0:B 335 117 0.0389 0.0836 0.2393 1.3 6ai0:A
6 8bx8:C 3947 76 0.0278 0.0051 0.2632 1.5 7k58:C, 7k5b:C, 7kek:C
7 4i91:A 465 131 0.0486 0.0753 0.2672 1.7 3ibd:A, 3qoa:A, 3qu8:A, 3qu8:B, 3qu8:C, 3qu8:E, 3qu8:D, 3qu8:F, 4rql:A, 4rql:B, 4rrt:A, 4rrt:B, 3ua5:A, 3ua5:B, 5uap:A, 5uap:B, 5uda:A, 5uda:B, 5uec:A, 5ufg:A, 5wbg:A, 5wbg:B, 5wbg:C, 5wbg:D, 5wbg:E, 5wbg:F, 4zv8:A
8 4h3s:A 585 66 0.0306 0.0376 0.3333 3.0
9 3slr:A 376 106 0.0431 0.0824 0.2925 3.1
10 2ggq:A 401 88 0.0333 0.0599 0.2727 3.7 5z09:A, 5z09:B, 5z09:C, 5z09:D
11 8gzh:C 1052 50 0.0222 0.0152 0.3200 3.7 8gzg:C
12 6npb:B 378 73 0.0306 0.0582 0.3014 6.6 6npb:A, 6npc:A, 6npc:B, 6npd:A, 6npd:B
13 5uzh:A 345 47 0.0194 0.0406 0.2979 7.4
14 8oif:A 704 240 0.0736 0.0753 0.2208 9.3

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218