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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
EPFLIGVSGGTASGKSSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTL
KEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISERGRDL
EQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNG

The query sequence (length=213) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6n55:E 214 213 1.0000 0.9953 1.0000 3.84e-157 6n53:A, 6n53:B, 6n54:A, 6n54:B, 6n55:D, 6n55:F, 6pwz:D, 6pwz:E, 6pwz:H, 7sql:A, 7sql:C, 7sql:B, 7sql:D, 1udw:A, 1udw:B, 1uei:A, 1uei:B, 1uej:A, 1uej:B, 1uj2:A, 1uj2:B, 1xrj:A, 1xrj:B
2 2uvq:A 211 212 0.7934 0.8009 0.7972 9.93e-128
3 3asz:B 208 202 0.4178 0.4279 0.4406 8.60e-58 3asz:A, 3w34:A, 3w34:B, 3w8r:A, 3w8r:B
4 7z67:A 393 188 0.2629 0.1425 0.2979 1.18e-18
5 6kev:A 317 187 0.1878 0.1262 0.2139 4.08e-11
6 3tqc:B 305 227 0.2723 0.1902 0.2555 2.52e-06 3tqc:A
7 2ges:A 308 220 0.2394 0.1656 0.2318 3.26e-06 3aez:A, 3af0:A, 3af1:A, 3af2:A, 3af3:A, 3avo:A, 3avq:A, 4bfs:A, 4bft:A, 4bft:B, 4bfu:A, 4bfu:B, 4bfv:A, 4bfv:B, 4bfw:A, 4bfw:B, 4bfx:A, 4bfx:B, 4bfy:A, 4bfy:B, 4bfz:A, 4bfz:B, 2get:A, 2geu:A, 2gev:A, 2zs7:A, 2zs8:A, 2zs9:A, 2zsa:A, 2zsb:A, 2zsd:A, 2zse:A, 2zsf:A
8 1esm:A 311 122 0.1502 0.1029 0.2623 0.006 1esm:B, 1esm:C, 1esm:D, 1esn:A, 1esn:B, 1esn:C, 1esn:D, 4f7w:A, 4f7w:C, 4f7w:B, 4f7w:D, 4f7w:E, 4f7w:F, 4f7w:G, 4f7w:H, 4gi7:A, 4gi7:C, 4gi7:B, 4gi7:D, 4gi7:E, 4gi7:F, 4gi7:G, 4gi7:H, 4ne2:A, 4ne2:B, 1sq5:A, 1sq5:B, 1sq5:C, 1sq5:D
9 2zkm:X 708 86 0.1127 0.0339 0.2791 0.21 2fju:B
10 2p0e:A 190 149 0.1455 0.1632 0.2081 0.60 2qg6:A, 2ql6:A, 2ql6:E, 2ql6:B, 2ql6:C, 2ql6:F, 2ql6:D, 2ql6:G, 2ql6:H, 2ql6:I, 2ql6:M, 2ql6:J, 2ql6:K, 2ql6:L, 2ql6:N, 2ql6:O, 2ql6:P, 2qsy:A, 2qsz:A, 2qt0:A, 2qt1:A
11 5kz7:A 296 101 0.1174 0.0845 0.2475 0.71 5kz7:B
12 5l3w:A 297 56 0.0845 0.0606 0.3214 1.2 5l3s:B, 5l3s:D, 5l3s:F, 5l3s:H
13 8r3p:A 672 66 0.0610 0.0193 0.1970 2.3 8r3p:B, 8r3p:C, 8r3p:D
14 1qf9:A 194 27 0.0563 0.0619 0.4444 3.6 1uke:A, 2ukd:A, 3ukd:A, 4ukd:A, 5ukd:A
15 8jxu:A 1410 61 0.0845 0.0128 0.2951 3.9 8jxq:A
16 6z6g:A 2142 67 0.0986 0.0098 0.3134 4.7 5amr:A
17 7tuv:A 672 42 0.0516 0.0164 0.2619 4.9
18 4bru:A 375 60 0.0798 0.0453 0.2833 5.1
19 2c95:A 195 24 0.0610 0.0667 0.5417 6.7 3adk:A, 2c95:B, 1z83:A, 1z83:B, 1z83:C
20 6tvk:AAA 660 63 0.0704 0.0227 0.2381 7.4
21 6pjx:A 542 134 0.1315 0.0517 0.2090 8.1 4tnb:A, 4tnd:A, 8uap:A, 8uaq:A, 4wnk:A
22 6k35:A 640 27 0.0469 0.0156 0.3704 8.3 6k35:B
23 6hul:B 416 100 0.1315 0.0673 0.2800 8.8

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218