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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ENYRDIALAFLDESADSGTINAWVNEFAYQGFDPKRIVQLVKERGTAKGRDWKKDVKMMIVLNLVRGNKPEAMMKKMSEK
GASIVANLISVYQLKEGNPGRDTITLSRVSAAFVPWTVQALRVLSESLPVSGTTMDAIAGVTYPRAMMHPSFAGIIDLDL
PNGAGATIADAHGLFMIEFSKTINPSLRTKQANEVAATFEKPNMAAMSGRFFTREDKKKLLIAVGIIDEDLVLASAVVRS
AEKYRAKVG

The query sequence (length=249) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4csf:K 251 249 1.0000 0.9920 1.0000 0.0 4csf:A, 4csf:B, 4csf:F, 4csf:C, 4csf:D, 4csf:E, 4csf:G, 4csf:H, 4csf:L, 4csf:I, 4csf:J, 4csf:M, 4csf:N, 4csf:R, 4csf:O, 4csf:P, 4csf:Q, 4csf:S, 4csf:T, 4csf:X, 4csf:U, 4csf:V, 4csf:W
2 3ov9:A 245 230 0.4739 0.4816 0.5130 4.82e-83 4h5o:A, 4h5o:B, 4h5o:D, 4h5o:F, 4h5o:G, 4h5o:C, 4h5o:E, 4h5o:H, 4h5o:I, 4h5o:J, 4h5p:A, 4h5p:B, 4h5p:C, 4h5p:D, 4h5q:A, 4h5q:B, 4h5q:C, 3ouo:A, 3ouo:B, 3ouo:C, 3ov9:B, 3ov9:C, 4v9e:AA, 4v9e:AB, 4v9e:AC, 4v9e:AD, 4v9e:AE, 4v9e:AF, 4v9e:AG, 4v9e:AH, 4v9e:AI, 4v9e:AJ, 4v9e:AK, 4v9e:AL, 4v9e:AM, 4v9e:AN, 4v9e:AO, 4v9e:AP, 4v9e:AQ, 4v9e:AR, 4v9e:BA, 4v9e:BB, 4v9e:BC, 4v9e:BD, 4v9e:BE, 4v9e:BF, 4v9e:BG, 4v9e:BH, 4v9e:BI, 4v9e:BJ, 4v9e:BK, 4v9e:BL, 4v9e:BM, 4v9e:BN, 4v9e:BO, 4v9e:BP, 4v9e:BQ, 4v9e:BR
3 4j4v:D 246 244 0.3293 0.3333 0.3361 2.19e-30 4j4v:A, 4j4v:B, 4j4v:C, 4j4v:E
4 1a5o:C 566 96 0.1044 0.0459 0.2708 0.90 1a5n:C, 1ef2:A, 1ejr:C, 1ejs:C, 1ejt:C, 1eju:C, 1ejv:C, 1fwa:C, 1fwb:C, 1fwc:C, 1fwd:C, 1fwe:C, 1fwf:C, 1fwg:C, 1fwh:C, 1fwi:C, 1fwj:C, 2kau:C, 1krb:C, 1krc:C
5 6jdd:A 176 88 0.0924 0.1307 0.2614 1.5
6 6trq:C 336 38 0.0482 0.0357 0.3158 2.6 5bv3:A, 5bv3:C, 6trq:A, 6trq:D
7 4cnj:A 391 68 0.0843 0.0537 0.3088 4.7 4cnj:B, 4cnj:C, 4cnj:D, 4cnk:A, 4cnk:B
8 2vy0:A 264 59 0.0643 0.0606 0.2712 5.3 2vy0:B
9 5ex2:A 267 41 0.0602 0.0562 0.3659 5.8 5ex2:B
10 8a8m:B 298 46 0.0643 0.0537 0.3478 7.6 3fme:A, 8p7j:A, 8p7j:B, 8pm3:A, 8pm3:B, 8pm3:C, 8pm3:D, 3vn9:A
11 4gae:A 416 68 0.0643 0.0385 0.2353 8.3 3au8:A, 3au8:B, 3au9:A, 3au9:B, 3aua:A, 3aua:B, 4gae:B, 5jaz:A, 5jaz:B, 5jbi:A, 5jbi:B, 5jc1:A, 5jc1:B, 5jmp:A, 5jmp:B, 5jmw:A, 5jmw:B, 5jnl:A, 5jnl:B, 8jnv:A, 8jnv:B, 8jnw:A, 8jnw:B, 5jo0:A, 5jo0:B, 4kp7:A, 4kp7:B, 3wqq:A, 3wqq:B, 3wqr:A, 3wqr:B, 3wqs:B, 4y67:A, 4y67:B, 4y6p:A, 4y6p:B, 4y6r:A, 4y6r:B, 4y6s:A, 4y6s:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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