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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ENLYFQGMKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTN
FRVMLVKVGEQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNW
TKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGD
EGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLLFHGEASEQLRTR
GAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVG
VDGSVYKLHPSFKERFHASVRRLTPSCEITFIESEEGSGRGAALVSAVACK

The query sequence (length=451) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3idh:A 453 453 0.9956 0.9912 0.9912 0.0 3a0i:X, 4dhy:A, 6e0e:A, 6e0i:A, 3f9m:A, 3fgu:A, 3fr0:A, 3goi:A, 3h1v:X, 3id8:A, 3imx:A, 4iwv:A, 4ixc:A, 4l3q:A, 4mle:A, 4mlh:A, 4no7:A, 3qic:A, 4rch:A, 3s41:A, 7t78:A, 7t78:B, 7t79:A, 7t79:B, 1v4s:A, 3vev:A, 3vey:A, 3vf6:A
2 4dch:A 434 448 0.9268 0.9631 0.9330 0.0 4ise:A, 4isf:A, 4isg:A, 5v4w:A, 5v4x:A
3 5hg1:A 867 438 0.5499 0.2860 0.5662 2.35e-180
4 5hg1:A 867 441 0.4922 0.2561 0.5034 1.50e-153
5 5hfu:B 897 440 0.5521 0.2776 0.5659 3.28e-180 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
6 5hfu:B 897 441 0.5322 0.2676 0.5442 6.22e-180 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
7 2nzt:B 867 439 0.5388 0.2803 0.5535 2.52e-179
8 2nzt:B 867 438 0.5388 0.2803 0.5548 4.07e-170
9 1qha:A 903 442 0.5366 0.2680 0.5475 7.92e-177 1bg3:A, 1bg3:B, 1cza:N, 1dgk:N, 4f9o:A, 4f9o:B, 4foe:A, 4foe:B, 4foi:A, 4foi:B, 4fpa:A, 4fpa:B, 4fpb:A, 4fpb:B, 1hkb:A, 1hkb:B, 1hkc:A, 1qha:B
10 1qha:A 903 441 0.4900 0.2447 0.5011 2.47e-164 1bg3:A, 1bg3:B, 1cza:N, 1dgk:N, 4f9o:A, 4f9o:B, 4foe:A, 4foe:B, 4foi:A, 4foi:B, 4fpa:A, 4fpa:B, 4fpb:A, 4fpb:B, 1hkb:A, 1hkb:B, 1hkc:A, 1qha:B
11 3hm8:A 441 439 0.5166 0.5283 0.5308 7.86e-173 3hm8:B, 3hm8:C, 3hm8:D
12 1bdg:A 444 446 0.4368 0.4437 0.4417 5.52e-124
13 3o5b:A 479 459 0.3259 0.3069 0.3203 6.14e-88 3o5b:B, 3o80:A, 3o8m:A
14 3b8a:X 470 460 0.3415 0.3277 0.3348 1.72e-78
15 6jj7:A 465 455 0.3525 0.3419 0.3495 9.03e-78 6jj7:C, 6jj7:E, 6jj8:C, 6jj8:A, 6jj8:B, 6jj9:C, 6jj9:A, 6jj9:E, 5zqt:A, 5zqt:B, 5zqt:C
16 4qs7:A 455 458 0.3548 0.3516 0.3493 1.45e-75 4qs9:A
17 6pdt:A 500 488 0.3237 0.2920 0.2992 1.16e-62 6pdt:B, 6pdt:C, 6pdt:D
18 6ksr:A 467 478 0.3060 0.2955 0.2887 1.05e-48
19 7zzi:B 467 476 0.2971 0.2869 0.2815 2.22e-46 7zzi:A
20 2yhx:A 457 186 0.1042 0.1028 0.2527 2.72e-08
21 7uaj:B 512 27 0.0288 0.0254 0.4815 0.93 2fk4:A, 8gcr:A, 4giz:C, 4giz:D, 8jrn:D, 8jrn:B, 8jro:D, 8jro:B, 8jrp:B, 8jrp:D, 8jrq:B, 8jrq:D, 8jrr:B, 8jrr:D, 8r1f:B, 8r1g:B, 8r1g:E, 6siv:B, 6sja:B, 7uaj:A, 7uaj:C, 7uaj:D, 4xr8:F
22 6jdc:A 269 102 0.0554 0.0929 0.2451 1.1
23 3jc9:Ma 355 75 0.0421 0.0535 0.2533 1.4 3jc9:Mb, 3jc9:Mc, 3jc9:Md, 3jc9:Me, 3jc9:Mf, 3jc9:Mg, 3jc9:Mh, 3jc9:Mi, 3jc9:Mj, 3jc9:Mk, 3jc9:Ml
24 8x2i:A 2303 63 0.0355 0.0069 0.2540 1.8
25 8x2h:A 2363 63 0.0355 0.0068 0.2540 1.8 8jb5:A, 2vkd:A, 2vkd:B, 2vkd:C, 2vkh:A, 2vkh:B, 2vkh:C, 2vl8:A, 2vl8:B, 2vl8:C
26 6ymv:A 887 48 0.0355 0.0180 0.3333 2.8
27 4fdg:B 592 66 0.0421 0.0321 0.2879 2.9 8eaf:A, 8eaf:B, 8eaf:C, 8eaf:D, 8eaf:E, 8eaf:F, 8eag:B, 8eag:C, 8eag:D, 8eag:E, 8eag:F, 8eag:A, 8eah:A, 8eah:B, 8eah:C, 8eah:D, 8eah:E, 8eah:F, 8eai:B, 8eai:C, 8eai:D, 8eai:E, 8eai:F, 8eai:A, 8eaj:A, 8eaj:B, 8eaj:C, 8eaj:D, 8eaj:E, 8eaj:F, 8eak:B, 8eak:C, 8eak:D, 8eak:E, 8eak:A, 8eak:F, 8eal:A, 8eal:B, 8eal:C, 8eal:D, 8eal:E, 8eal:F, 8eam:B, 8eam:C, 8eam:D, 8eam:E, 8eam:A, 8eam:F, 4fdg:A, 4fdg:C, 4fdg:D, 4fdg:E, 6mii:A, 6mii:B, 6mii:C, 6mii:D, 6mii:E, 6mii:F, 2vl6:A, 2vl6:B, 2vl6:C, 6wnz:B, 6wnz:A
28 8c5s:A 924 48 0.0355 0.0173 0.3333 3.0 8ap1:A, 8att:A, 8atv:A, 8atw:A, 8c5u:A, 8q63:A, 6ymw:A
29 1lkx:C 679 97 0.0576 0.0383 0.2680 3.1 1lkx:A, 1lkx:B, 1lkx:D
30 7s6c:C 480 99 0.0554 0.0521 0.2525 3.2 7s6d:C
31 3hqp:A 498 57 0.0399 0.0361 0.3158 3.3 3hqo:K, 3hqo:A, 3hqo:B, 3hqo:C, 3hqp:B, 3hqp:C, 3hqp:D, 3hqp:E, 3hqp:F, 3hqp:G, 3hqp:H, 3hqp:I, 3hqp:J, 3hqp:K, 3hqp:L, 3hqp:M, 3hqp:N, 3hqp:O, 3hqp:P, 3hqq:A, 3hqq:B, 3hqq:C, 3hqq:D, 3hqq:E, 3hqq:F, 3hqq:G, 3hqq:H, 3hqq:I, 3hqq:J, 3hqq:K, 3hqq:L, 3hqq:M, 3hqq:N, 3hqq:O, 3hqq:P, 3hqq:Q, 3hqq:R, 3hqq:S, 3hqq:T, 3hqq:U, 3hqq:V, 3hqq:W, 3hqq:X, 3pp7:B, 3qv6:A, 3qv7:D, 3qv7:A, 3qv8:D, 3srk:A
32 4r7y:A 591 66 0.0421 0.0321 0.2879 3.4 4r7y:B, 4r7z:A, 4r7z:B, 4r7z:C, 4r7z:D, 4r7z:E, 4r7z:F, 4r7z:G, 4r7z:H, 4r7z:I, 4r7z:P, 4r7z:J, 4r7z:K, 4r7z:L, 4r7z:M, 4r7z:N, 4r7z:O
33 3i5o:A 582 80 0.0532 0.0412 0.3000 6.1 3i5o:B, 4jsd:A, 4jso:A, 2o7i:A
34 8ef9:A 599 39 0.0266 0.0200 0.3077 8.6 8efc:A, 8efk:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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