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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
ELVVISKSIVNPRSLKKPTSVKKIQLTPWDLSRLRFGYLQRGLLFHKIEVKQLQASLSVALDRFYPLAGRLVKLKNDDDT
VSFFISCDGSGVEFVHAVAKNIELSDVLELSGSVPGFFASFFPATGIKNYHGVSRSLLMVQVTEMKDGVFIGFGYNSTVA
DATSIWKFINAWSEICSKDSSGSQTFQRRLHLKGWFFDEIDYPIHIPDPETKPTSYVTTPTNLQEKMFHVTKENVLKLDA
KANDEADQKISSIQAVLAYIWRSMVKHSGMSREEETHCRLPINMRQRLNPPLEEECFGNVSQTGIATVTVGELLDHGLGW
AAMQINNMELSQTDEKAKAFAENWVKNIKIPVSVGSKDLVVTNSHRFDVYCNDFGWGKPIAARAGPPYLNGRLVVFKGIG
EASLDFQACLLPQVVEKLVKDAEFNEYVSIV

The query sequence (length=431) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6wao:A 431 431 1.0000 1.0000 1.0000 0.0
2 6wao:B 406 431 0.9420 1.0000 0.9420 0.0
3 8h8i:A 431 418 0.3805 0.3805 0.3923 3.98e-96 8hbt:A
4 5kjt:A 431 381 0.2483 0.2483 0.2808 1.83e-28 5kju:A
5 6lpv:A 434 389 0.2459 0.2442 0.2725 2.12e-24
6 5kjw:A 425 346 0.2274 0.2306 0.2832 2.38e-24 5kjw:B
7 5fal:A 435 346 0.2088 0.2069 0.2601 3.35e-23 5fan:A, 4kec:A
8 8dqo:B 437 335 0.1972 0.1945 0.2537 8.06e-19 8dqo:A, 8dqp:A, 8dqp:B, 8dqq:A, 8dqq:B, 8dqr:A
9 2e1t:A 440 411 0.2506 0.2455 0.2628 1.02e-15 2e1t:B
10 6lpw:B 436 340 0.1972 0.1950 0.2500 7.64e-15
11 7dex:A 460 428 0.2599 0.2435 0.2617 1.16e-13
12 6mk2:A 407 351 0.2088 0.2211 0.2564 6.22e-13
13 2xr7:A 452 406 0.2181 0.2080 0.2315 1.08e-11
14 8j9h:A1 137 42 0.0394 0.1241 0.4048 0.94 8j9j:A1
15 3dtn:A 220 99 0.0650 0.1273 0.2828 3.0 3dtn:B
16 7egh:A 630 51 0.0441 0.0302 0.3725 3.2 7edx:A, 7eg7:A, 7eg8:A, 7eg9:A, 7ega:A, 7egd:A, 7egj:A, 7ena:DA, 5fur:G, 6mzm:A
17 2zba:D 391 199 0.0951 0.1049 0.2060 3.3
18 6tvo:A 1011 50 0.0348 0.0148 0.3000 4.3 2l1l:B
19 8qlp:B 452 35 0.0302 0.0288 0.3714 8.9 8qlp:F, 8qlp:J, 8qlp:N
20 8wuw:H 529 81 0.0650 0.0529 0.3457 9.2 8wuw:A, 8wuw:B, 8wuw:I, 8wuw:C, 8wuw:J, 8wuw:D, 8wuw:K, 8wuw:E, 8wuw:L, 8wuw:F, 8wuw:M, 8wuw:G, 8wuw:N, 8wux:A, 8wux:H, 8wux:B, 8wux:I, 8wux:C, 8wux:J, 8wux:D, 8wux:K, 8wux:E, 8wux:L, 8wux:F, 8wux:M, 8wux:G, 8wux:N

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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